ATE459355T1 - Verfahren zur behandlung von erkrankungen mit mangel an thiolhaltiger verbindung - Google Patents
Verfahren zur behandlung von erkrankungen mit mangel an thiolhaltiger verbindungInfo
- Publication number
- ATE459355T1 ATE459355T1 AT03781632T AT03781632T ATE459355T1 AT E459355 T1 ATE459355 T1 AT E459355T1 AT 03781632 T AT03781632 T AT 03781632T AT 03781632 T AT03781632 T AT 03781632T AT E459355 T1 ATE459355 T1 AT E459355T1
- Authority
- AT
- Austria
- Prior art keywords
- compounds
- deficiencing
- thiole
- thiol
- treating diseases
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- YTPLMLYBLZKORZ-UHFFFAOYSA-N Thiophene Chemical class C=1C=CSC=1 YTPLMLYBLZKORZ-UHFFFAOYSA-N 0.000 title 1
- 201000010099 disease Diseases 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- 150000003573 thiols Chemical class 0.000 abstract 3
- 201000003883 Cystic fibrosis Diseases 0.000 abstract 2
- 238000002560 therapeutic procedure Methods 0.000 abstract 2
- 108010006533 ATP-Binding Cassette Transporters Proteins 0.000 abstract 1
- 102000005416 ATP-Binding Cassette Transporters Human genes 0.000 abstract 1
- 108010078791 Carrier Proteins Proteins 0.000 abstract 1
- 101000946797 Mus musculus C-C motif chemokine 9 Proteins 0.000 abstract 1
- 230000000638 stimulation Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/63—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
- A61K31/635—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide having a heterocyclic ring, e.g. sulfadiazine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
- A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
- A61K31/366—Lactones having six-membered rings, e.g. delta-lactones
- A61K31/37—Coumarins, e.g. psoralen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/428—Thiazoles condensed with carbocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/60—Salicylic acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/60—Salicylic acid; Derivatives thereof
- A61K31/606—Salicylic acid; Derivatives thereof having amino groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2121/00—Preparations for use in therapy
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Steroid Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US42280202P | 2002-10-31 | 2002-10-31 | |
US10/400,980 US20040087527A1 (en) | 2002-10-31 | 2003-03-27 | Methods for treatment of thiol-containing compound deficient conditions |
PCT/US2003/034723 WO2004042020A2 (en) | 2002-10-31 | 2003-10-30 | Methods for treatment of thiol-containing compound deficient conditions |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE459355T1 true ATE459355T1 (de) | 2010-03-15 |
Family
ID=32179655
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT03781632T ATE459355T1 (de) | 2002-10-31 | 2003-10-30 | Verfahren zur behandlung von erkrankungen mit mangel an thiolhaltiger verbindung |
Country Status (6)
Country | Link |
---|---|
US (3) | US20040087527A1 (de) |
EP (1) | EP1562563B1 (de) |
AT (1) | ATE459355T1 (de) |
AU (1) | AU2003287398A1 (de) |
DE (1) | DE60331574D1 (de) |
WO (1) | WO2004042020A2 (de) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7790762B2 (en) * | 2002-10-31 | 2010-09-07 | National Jewish Health | Compounds and methods for thiol-containing compound efflux and cancer treatment |
US20040087527A1 (en) * | 2002-10-31 | 2004-05-06 | Day Brian J. | Methods for treatment of thiol-containing compound deficient conditions |
US20080221029A1 (en) * | 2002-10-31 | 2008-09-11 | Regents Of The University Of Colorado | Methods for treatment of thiol-containing compound deficient conditions |
WO2004104022A2 (en) * | 2003-05-16 | 2004-12-02 | The General Hospital Corporation | Compositions comprising pathogen elicited epithelial chemoattractant (eicosanoid hepoxilin a3), inhibitors thereof and methods of use thereof |
WO2005044984A2 (en) * | 2003-10-15 | 2005-05-19 | Trustees Of Dartmouth College | Modulators of the abc transporter family and methods for their use |
US20070275894A1 (en) * | 2006-05-24 | 2007-11-29 | Bruce Stanton | Modulators of the ABC Transporter Family and Methods for Their Use |
WO2007024741A2 (en) * | 2005-08-24 | 2007-03-01 | National Jewish Medical And Research Center | Methods for treatment of thiol-containing compound deficient conditions |
WO2008154012A2 (en) * | 2007-06-11 | 2008-12-18 | University Of Vermont And State Agricultural College | Treatments involving glutaredoxins and similar agents |
CN101322700B (zh) * | 2007-06-13 | 2010-08-25 | 中国科学院生物物理研究所 | 柚皮素和柚皮苷作为转化生长因子-β1信号通路抑制剂在制备药物中的应用 |
US20130345312A1 (en) * | 2010-08-06 | 2013-12-26 | Orion D. Jankowski | Treatment of mitochondrial diseases with naphthoquinones |
JP6393684B2 (ja) | 2012-09-07 | 2018-09-19 | バイオエレクトロン テクノロジー コーポレイション | 個体のレドックス状態の調節において使用するためのキノン誘導体 |
CN109406467B (zh) * | 2018-10-16 | 2021-01-29 | 商丘师范学院 | 用于atp检测的分裂适配体传感器及其应用 |
WO2020124152A1 (en) * | 2018-12-19 | 2020-06-25 | Monash University | Assay for screening drugs |
CN113476437A (zh) * | 2021-08-10 | 2021-10-08 | 江南大学 | 刺芒柄花素在制备用于防治急性胰腺炎类疾病的药物中的应用 |
CN113797195B (zh) * | 2021-08-20 | 2022-09-13 | 山东第一医科大学(山东省医学科学院) | 3-芳基香豆素类化合物的应用、抗癌增敏组合物及抗癌组合物 |
Family Cites Families (35)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US594814A (en) * | 1897-11-30 | Island | ||
US5310732A (en) * | 1986-02-03 | 1994-05-10 | The Scripps Research Institute | 2-halo-2'-deoxyadenosines in the treatment of rheumatoid arthritis |
US5075116A (en) | 1989-04-20 | 1991-12-24 | Lahaye Laboratories, Inc. | Composition and method for treatment of macular degeneration |
US5010069A (en) * | 1989-05-15 | 1991-04-23 | Marion Laboratories, Inc. | Stable liquid form of 5-aminosalicylic acid |
US5238683A (en) | 1989-11-24 | 1993-08-24 | The United States Of America As Represented By The Department Of Health And Human Services | Aerosol preparation of glutathione and a method for augmenting glutathione level in lungs |
US6025473A (en) | 1992-10-27 | 2000-02-15 | Queen's University At Kingston | Multidrug resistance proteins |
US5489519A (en) | 1992-10-27 | 1996-02-06 | Queen's University At Kingston | Multidrug resistance protein |
US5766880A (en) | 1992-10-27 | 1998-06-16 | Queen's University At Kingston | Isolated nucleic acid molecules encoding multidrug resistance proteins |
CA2140660A1 (en) * | 1993-06-13 | 1994-12-22 | Uwe R. Juergens | Use of terpene compounds for reduced release of arachidonic acid and of inflammation mediators |
US5994339A (en) | 1993-10-15 | 1999-11-30 | University Of Alabama At Birmingham Research Foundation | Oxidant scavengers |
US6127356A (en) | 1993-10-15 | 2000-10-03 | Duke University | Oxidant scavengers |
WO1997016441A1 (en) | 1995-10-31 | 1997-05-09 | Merck & Co., Inc. | Substituted aryl pyrroles, compositions containing such compounds and methods of use |
RU2089179C1 (ru) | 1995-12-14 | 1997-09-10 | Закрытое акционерное общество "ВАМ" | Стимулятор эндогенной продукции цитокинов и гепопоэтических факторов и способ его использования |
CA2197058A1 (en) * | 1996-06-05 | 1997-12-06 | Avery B. Nathens | Anti-inflammatory agent |
US5985261A (en) | 1996-06-28 | 1999-11-16 | National Jewish Medical And Research Center | Use of thioredoxin-like molecules for induction of MnSOD to treat oxidative damage |
US5948814A (en) * | 1997-02-20 | 1999-09-07 | The Curators Of The University Of Missouri | Genistein for the treatment of cystic fibrosis |
FR2763845B1 (fr) | 1997-05-30 | 2003-04-18 | Centre Nat Rech Scient | Produits anti-cancereux pour le traitement de la mucoviscidose |
US6372772B1 (en) | 1997-08-01 | 2002-04-16 | Prolx Pharmaceuticals Corporation | Inhibitors of redox signaling and methods of using same |
US5972995A (en) * | 1997-10-16 | 1999-10-26 | Children's Hospital Medical Center Of Northern California | Compositions and methods for cystic fibrosis therapy |
US6407065B1 (en) * | 1998-01-23 | 2002-06-18 | Novartis Ag | VLA-4 antagonists |
US6448472B1 (en) | 1999-02-05 | 2002-09-10 | Board Of Regents, The University Of Texas System | Genetic and epigenetic manipulation of ABC transporters and ectophosphatases for the conference of hormone and herbicide resistance |
CA2395191A1 (en) | 1999-12-23 | 2001-06-28 | Tedman Ehlers | Chalcone and its analogs as agents for the inhibition of angiogenesis and related disease states |
GB2362101A (en) * | 2000-05-12 | 2001-11-14 | Astrazeneca Ab | Treatment of chronic obstructive pulmonary disease |
WO2002032374A2 (en) * | 2000-10-18 | 2002-04-25 | Immunex Corporation | Methods for treating il-18 mediated disorders |
US7122544B2 (en) * | 2000-12-06 | 2006-10-17 | Signal Pharmaceuticals, Llc | Anilinopyrimidine derivatives as IKK inhibitors and compositions and methods related thereto |
US7129242B2 (en) * | 2000-12-06 | 2006-10-31 | Signal Pharmaceuticals, Llc | Anilinopyrimidine derivatives as JNK pathway inhibitors and compositions and methods related thereto |
AUPR363301A0 (en) * | 2001-03-08 | 2001-04-05 | Novogen Research Pty Ltd | Dimeric isoflavones |
AU2002254342A1 (en) * | 2001-03-23 | 2002-10-08 | The Board Of Trustees Of The University Of Illinois | Compounds capable of modulating the activity of multidrug transporters and therapeutic use of the same |
WO2002085297A2 (en) * | 2001-04-24 | 2002-10-31 | East Carolina University | Compositions & formulations with a non-glucocorticoid steroid &/or a ubiquinone & kit for treatment of respiratory & lung disease |
CA2442969A1 (en) * | 2001-05-09 | 2002-11-14 | Novartis Ag | Methods for selective immunomodulation using pimecrolimus |
JP2005528383A (ja) * | 2002-04-10 | 2005-09-22 | ミラー,フレッド,エイチ. | 多重相・複数コンパートメントカプセルシステム |
US20040081647A1 (en) * | 2002-08-27 | 2004-04-29 | Afeyan Noubar B. | Adzymes and uses thereof |
MXPA05004580A (es) * | 2002-10-29 | 2005-07-26 | Transave Inc | Liberacion sostenida de anti - infecciosos. |
US20040087527A1 (en) * | 2002-10-31 | 2004-05-06 | Day Brian J. | Methods for treatment of thiol-containing compound deficient conditions |
DE102005044156A1 (de) | 2005-09-15 | 2007-03-29 | Riemser Arzneimittel Ag | Substituierte Acetophenonderivate |
-
2003
- 2003-03-27 US US10/400,980 patent/US20040087527A1/en not_active Abandoned
- 2003-10-30 DE DE60331574T patent/DE60331574D1/de not_active Expired - Lifetime
- 2003-10-30 WO PCT/US2003/034723 patent/WO2004042020A2/en not_active Application Discontinuation
- 2003-10-30 AT AT03781632T patent/ATE459355T1/de not_active IP Right Cessation
- 2003-10-30 AU AU2003287398A patent/AU2003287398A1/en not_active Abandoned
- 2003-10-30 EP EP03781632A patent/EP1562563B1/de not_active Expired - Lifetime
-
2005
- 2005-08-24 US US11/211,369 patent/US7498047B2/en not_active Expired - Lifetime
-
2014
- 2014-02-13 US US14/180,281 patent/US20140162986A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
US20060058245A1 (en) | 2006-03-16 |
EP1562563A4 (de) | 2005-12-28 |
US20040087527A1 (en) | 2004-05-06 |
WO2004042020A2 (en) | 2004-05-21 |
US7498047B2 (en) | 2009-03-03 |
AU2003287398A1 (en) | 2004-06-07 |
US20140162986A1 (en) | 2014-06-12 |
AU2003287398A8 (en) | 2004-06-07 |
WO2004042020A3 (en) | 2005-02-03 |
EP1562563B1 (de) | 2010-03-03 |
DE60331574D1 (de) | 2010-04-15 |
EP1562563A2 (de) | 2005-08-17 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |