ATE454404T1 - Intrazelluläre antikörper - Google Patents
Intrazelluläre antikörperInfo
- Publication number
- ATE454404T1 ATE454404T1 AT03776984T AT03776984T ATE454404T1 AT E454404 T1 ATE454404 T1 AT E454404T1 AT 03776984 T AT03776984 T AT 03776984T AT 03776984 T AT03776984 T AT 03776984T AT E454404 T1 ATE454404 T1 AT E454404T1
- Authority
- AT
- Austria
- Prior art keywords
- intracellular
- molecule
- immunoglobulin
- target
- domain
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/32—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/569—Single domain, e.g. dAb, sdAb, VHH, VNAR or nanobody®
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
- C07K2317/622—Single chain antibody (scFv)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Oncology (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0226729.2A GB0226729D0 (en) | 2002-11-15 | 2002-11-15 | Intracellular antibodies |
PCT/GB2003/004942 WO2004046185A2 (en) | 2002-11-15 | 2003-11-14 | Intracellular antibodies |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE454404T1 true ATE454404T1 (de) | 2010-01-15 |
Family
ID=9947935
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT03776984T ATE454404T1 (de) | 2002-11-15 | 2003-11-14 | Intrazelluläre antikörper |
Country Status (10)
Country | Link |
---|---|
US (2) | US20050272107A1 (de) |
EP (1) | EP1560853B1 (de) |
JP (1) | JP2006518188A (de) |
AT (1) | ATE454404T1 (de) |
AU (1) | AU2003286241A1 (de) |
CA (1) | CA2506124A1 (de) |
DE (1) | DE60330893D1 (de) |
ES (1) | ES2337570T3 (de) |
GB (1) | GB0226729D0 (de) |
WO (1) | WO2004046185A2 (de) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2004033485A2 (en) * | 2002-10-09 | 2004-04-22 | The Trustees Of Boston University | Nucleic acid supported protein complementation |
US20090029370A1 (en) * | 2005-10-27 | 2009-01-29 | Trustees Of Boston University | Real time nucleic acid detection in vivo using protein complementation |
US20090220942A1 (en) * | 2005-10-27 | 2009-09-03 | Natalia Broude | Activated split-polypeptides and methods for their production and use |
AU2007352344A1 (en) * | 2006-10-27 | 2008-11-06 | St. Jude Children's Research Hospital | Targeted split biomolecular conjugates for the treatment of diseases, malignancies and disorders, and methods of their production |
GB0911215D0 (en) | 2009-06-29 | 2009-08-12 | Univ Erasmus Medical Ct | Gamma globin therapy |
TWI450415B (zh) * | 2010-03-23 | 2014-08-21 | Lg Innotek Co Ltd | 發光裝置、發光裝置封裝件及照明系統 |
GB201103631D0 (en) * | 2011-03-03 | 2011-04-13 | Univ Leeds | Identification of candidate therapeutics |
TWI591074B (zh) * | 2011-12-05 | 2017-07-11 | X 染色體有限公司 | PDGF受體β結合多肽 |
JP6073038B2 (ja) | 2012-08-22 | 2017-02-01 | モガム バイオテクノロジー リサーチ インスティチュート | 安定化された免疫グロブリン可変ドメイン選別方法及び選別されたドメインの応用 |
BR112015010911A2 (pt) | 2012-11-16 | 2022-10-25 | Transposagen Biopharmaceuticals Inc | Enzimas específicas de sítio e métodos de uso |
SG10201800800YA (en) | 2013-05-06 | 2018-03-28 | Scholar Rock Inc | Compositions and methods for growth factor modulation |
US20170107541A1 (en) * | 2014-06-17 | 2017-04-20 | Poseida Therapeutics, Inc. | A method for directing proteins to specific loci in the genome and uses thereof |
LT3209685T (lt) | 2014-10-23 | 2019-08-26 | Singh Molecular Medicine, Llc | Antikūnai su vienu duomenu, nukreipti prieš viduląstelinius antigenus |
US20170267784A1 (en) | 2014-10-23 | 2017-09-21 | Singh Molecular Medicine, Llc | Single domain antibodies directed against intracellular antigens |
US9879087B2 (en) | 2014-11-12 | 2018-01-30 | Siamab Therapeutics, Inc. | Glycan-interacting compounds and methods of use |
DK3218005T3 (da) | 2014-11-12 | 2023-03-27 | Seagen Inc | Glycan-interagerende forbindelser og anvendelsesfremgangsmåder |
AU2016278226B2 (en) | 2015-06-17 | 2021-08-12 | Poseida Therapeutics, Inc. | Compositions and methods for directing proteins to specific loci in the genome |
TWI746473B (zh) | 2015-11-02 | 2021-11-21 | 美商辛分子醫藥有限公司 | 針對細胞內抗原之單域抗體 |
IL258768B2 (en) | 2015-11-12 | 2023-11-01 | Siamab Therapeutics Inc | Compounds interacting with glycans and methods of use |
JP6293829B2 (ja) * | 2016-08-05 | 2018-03-14 | モガム インスティチュート フォー バイオメディカル リサーチMOGAM Institute for Biomedical Research | 安定化された免疫グロブリン可変ドメイン選別方法及び選別されたドメインの応用 |
WO2018094143A1 (en) | 2016-11-17 | 2018-05-24 | Siamab Therapeutics, Inc. | Glycan-interacting compounds and methods of use |
KR20240044544A (ko) | 2017-03-03 | 2024-04-04 | 씨젠 인크. | 글리칸-상호작용 화합물 및 사용 방법 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5919650A (en) * | 1990-04-22 | 1999-07-06 | Bristol-Myers Squibb Co. | Method for inactivation of protein function |
DK0859841T3 (da) * | 1995-08-18 | 2002-09-09 | Morphosys Ag | Protein/(poly)peptidbiblioteker |
GB2344886B (en) * | 1999-03-10 | 2000-11-01 | Medical Res Council | Selection of intracellular immunoglobulins |
AU2003219277A1 (en) * | 2002-03-14 | 2003-09-29 | Medical Research Council | Intracellular antibodies |
US6919650B2 (en) * | 2002-05-31 | 2005-07-19 | Ballard Power Systems Corporation | Hybrid synchronization phase angle generation method |
-
2002
- 2002-11-15 GB GBGB0226729.2A patent/GB0226729D0/en not_active Ceased
-
2003
- 2003-11-14 WO PCT/GB2003/004942 patent/WO2004046185A2/en active Application Filing
- 2003-11-14 ES ES03776984T patent/ES2337570T3/es not_active Expired - Lifetime
- 2003-11-14 JP JP2004552863A patent/JP2006518188A/ja active Pending
- 2003-11-14 CA CA002506124A patent/CA2506124A1/en not_active Abandoned
- 2003-11-14 AU AU2003286241A patent/AU2003286241A1/en not_active Abandoned
- 2003-11-14 DE DE60330893T patent/DE60330893D1/de not_active Expired - Lifetime
- 2003-11-14 AT AT03776984T patent/ATE454404T1/de not_active IP Right Cessation
- 2003-11-14 EP EP03776984A patent/EP1560853B1/de not_active Expired - Lifetime
-
2005
- 2005-05-12 US US11/127,677 patent/US20050272107A1/en not_active Abandoned
-
2009
- 2009-06-22 US US12/456,845 patent/US20100143939A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
WO2004046185A3 (en) | 2004-09-23 |
AU2003286241A1 (en) | 2004-06-15 |
US20050272107A1 (en) | 2005-12-08 |
JP2006518188A (ja) | 2006-08-10 |
DE60330893D1 (de) | 2010-02-25 |
WO2004046185A2 (en) | 2004-06-03 |
US20100143939A1 (en) | 2010-06-10 |
ES2337570T3 (es) | 2010-04-27 |
EP1560853A2 (de) | 2005-08-10 |
CA2506124A1 (en) | 2004-06-03 |
GB0226729D0 (en) | 2002-12-24 |
EP1560853B1 (de) | 2010-01-06 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |