ATE453611T1 - Vitamin-d-analoga - Google Patents

Vitamin-d-analoga

Info

Publication number
ATE453611T1
ATE453611T1 AT02735556T AT02735556T ATE453611T1 AT E453611 T1 ATE453611 T1 AT E453611T1 AT 02735556 T AT02735556 T AT 02735556T AT 02735556 T AT02735556 T AT 02735556T AT E453611 T1 ATE453611 T1 AT E453611T1
Authority
AT
Austria
Prior art keywords
bis
phenyl
trifluoro
carbon atoms
radical
Prior art date
Application number
AT02735556T
Other languages
English (en)
Inventor
Jean-Michel Bernardon
Original Assignee
Galderma Res & Dev
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Galderma Res & Dev filed Critical Galderma Res & Dev
Application granted granted Critical
Publication of ATE453611T1 publication Critical patent/ATE453611T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C33/00—Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
    • C07C33/28—Alcohols containing only six-membered aromatic rings as cyclic part with unsaturation outside the aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/08—Antiseborrheics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/14—Drugs for dermatological disorders for baldness or alopecia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/16—Emollients or protectives, e.g. against radiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/18—Drugs for disorders of the endocrine system of the parathyroid hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C33/00—Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
    • C07C33/40—Halogenated unsaturated alcohols
    • C07C33/46—Halogenated unsaturated alcohols containing only six-membered aromatic rings as cyclic parts
    • C07C33/48—Halogenated unsaturated alcohols containing only six-membered aromatic rings as cyclic parts with unsaturation outside the aromatic rings
    • C07C33/486—Polycyclic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
    • C07C43/23—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing hydroxy or O-metal groups
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Pulmonology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Oncology (AREA)
  • Immunology (AREA)
  • Rheumatology (AREA)
  • Urology & Nephrology (AREA)
  • Obesity (AREA)
  • Cardiology (AREA)
  • Biomedical Technology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pain & Pain Management (AREA)
  • Emergency Medicine (AREA)
  • Virology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Communicable Diseases (AREA)
  • Vascular Medicine (AREA)
  • Toxicology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT02735556T 2001-05-22 2002-05-22 Vitamin-d-analoga ATE453611T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0106731A FR2825087B1 (fr) 2001-05-22 2001-05-22 Analogues de la vitamine d
PCT/FR2002/001726 WO2002094754A1 (fr) 2001-05-22 2002-05-22 Analogues de la vitamine d

Publications (1)

Publication Number Publication Date
ATE453611T1 true ATE453611T1 (de) 2010-01-15

Family

ID=8863543

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02735556T ATE453611T1 (de) 2001-05-22 2002-05-22 Vitamin-d-analoga

Country Status (20)

Country Link
US (1) US7700657B2 (de)
EP (1) EP1395538B1 (de)
JP (1) JP4629309B2 (de)
KR (1) KR100878728B1 (de)
CN (1) CN1267394C (de)
AT (1) ATE453611T1 (de)
AU (1) AU2002310684B2 (de)
BR (1) BR0205517A (de)
CA (1) CA2446149C (de)
CY (1) CY1109843T1 (de)
DE (1) DE60234920D1 (de)
DK (1) DK1395538T3 (de)
ES (1) ES2338995T3 (de)
FR (1) FR2825087B1 (de)
MX (1) MXPA03010628A (de)
PL (1) PL215582B1 (de)
PT (1) PT1395538E (de)
RU (1) RU2266274C2 (de)
WO (1) WO2002094754A1 (de)
ZA (1) ZA200300668B (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004069134A2 (en) * 2003-02-05 2004-08-19 Galderma Research & Development, S.N.C. Invert emulsion type composition containing at least one active agent sensitive to the presence of water, and its uses in cosmetics and in dermatology
US20050148557A1 (en) * 2003-07-29 2005-07-07 Jin Tian Use of Vitamin Ds to treat kidney disease
US20050124591A1 (en) * 2003-07-29 2005-06-09 Jin Tian Use of vitamin Ds to treat kidney disease
US20050192255A1 (en) * 2003-07-30 2005-09-01 Jin Tian Use of Vitamin Ds or Vitamin D analogs to treat cardiovascular disease
US20060171983A1 (en) * 2003-07-30 2006-08-03 Jin Tian Use of Vitamin D receptor activators or Vitamin D analogs to treat cardiovascular disease
EP1686972B1 (de) 2003-11-21 2008-03-12 Galderma Research & Development Sprühbare zusammensetzung zur verabreichung von vitamin d derivaten
FR2892936A1 (fr) * 2005-11-10 2007-05-11 Galderma Res & Dev Composition pharmaceutique ou cosmetique, et procede de solubilisation mixte pour preparer la composition.
US8470304B2 (en) * 2009-08-04 2013-06-25 Avidas Pharmaceuticals Llc Therapeutic vitamin D sun-protecting formulations and methods for their use
EP3603646B1 (de) 2009-08-14 2024-04-03 BPGbio, Inc. Vitamin d3 und analoge davon zur behandlung von alopezie
WO2017102790A1 (en) * 2015-12-18 2017-06-22 Dsm Ip Assets B.V. Biaromatic vitamin d analogs
US10849838B2 (en) 2015-12-18 2020-12-01 Dsm Ip Assets B.V. Biaromatic vitamin D analogs
JP6632006B2 (ja) * 2015-12-18 2020-01-15 ディーエスエム アイピー アセッツ ビー．ブイ．Ｄｓｍ Ｉｐ Ａｓｓｅｔｓ Ｂ．Ｖ． 新規化合物
CN108430439B (zh) * 2015-12-18 2021-03-02 帝斯曼知识产权资产管理有限公司 联芳香族维生素d类似物

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5650420A (en) 1994-12-15 1997-07-22 Pharmacia & Upjohn Company Pramipexole as a neuroprotective agent
FR2741876B1 (fr) 1995-12-01 1998-01-09 Cird Galderma Composes biaromatiques portant un groupement adamantyl en para, compositions pharmaceutiques et cosmetiques les contenant et utilisations
FR2757852B1 (fr) 1996-12-31 1999-02-19 Cird Galderma Composes stilbeniques a groupement adamantyl, compositions les contenant et utilisations
FR2785284B1 (fr) * 1998-11-02 2000-12-01 Galderma Res & Dev Analogues de la vitamine d
US6659922B1 (en) 2003-04-21 2003-12-09 Jao-Hsing Tsai Resistance adjustment mechanism for easy pull exerciser

Also Published As

Publication number Publication date
DE60234920D1 (de) 2010-02-11
US7700657B2 (en) 2010-04-20
RU2003136744A (ru) 2005-04-10
EP1395538B1 (de) 2009-12-30
CA2446149A1 (fr) 2002-11-28
FR2825087A1 (fr) 2002-11-29
WO2002094754A1 (fr) 2002-11-28
FR2825087B1 (fr) 2005-01-14
AU2002310684B2 (en) 2005-07-21
CN1549803A (zh) 2004-11-24
KR100878728B1 (ko) 2009-01-14
US20040224929A1 (en) 2004-11-11
CN1267394C (zh) 2006-08-02
PL363872A1 (en) 2004-11-29
JP4629309B2 (ja) 2011-02-09
MXPA03010628A (es) 2004-04-02
PL215582B1 (pl) 2013-12-31
EP1395538A1 (de) 2004-03-10
DK1395538T3 (da) 2010-03-15
ZA200300668B (en) 2004-06-22
BR0205517A (pt) 2003-07-01
ES2338995T3 (es) 2010-05-14
RU2266274C2 (ru) 2005-12-20
CY1109843T1 (el) 2014-09-10
KR20030019601A (ko) 2003-03-06
CA2446149C (fr) 2010-07-06
JP2004534038A (ja) 2004-11-11
PT1395538E (pt) 2010-02-12

Similar Documents

Publication Publication Date Title
ATE453611T1 (de) Vitamin-d-analoga
SE9700616D0 (sv) Alkylfenylbisacylfosfinoxid och fotoinitiatorblandningar
IL105481A0 (en) Phenyl sulfonamide derivatives and pharmaceutical compositions containing the same
MEP24608A (en) Azetidine derivatives, preparation thereof and pharmaceutical compositions containing same
DE69410092D1 (en) Phenyl heterocyclen als cyclooxygenase-2 inhibitoren
DE69918404D1 (de) Aminophenoxyessigsäure derivate als neuroschützende mittel
TW200420542A (en) A compound having TGF β inhibition activity and a medicinal composition containing the same
DE59812455D1 (de) Fluorpyrazol-biphenylamide als fungizide
BR9703447A (pt) Novos compostos 3-(piperid-4-il)-1,2-benzisoxazol e 3-(piperazin-4-il) 1,2-benzisoxazol processos para a preparação dos mesmos e composições farmacêuticas contendo os mesmo
TW200744589A (en) Pharmaceutical composition
BR0207846A (pt) Derivados heterocìclicos para o tratamento de câncer e outras doenças proliferativas
BRPI0511462A (pt) medicamentos e pró-medicamentos óculo-seletivos
IL196754A0 (en) Protein kinase c activity enhancer containing alkyl ether derivative or salt thereof
HUP0101958A2 (hu) Antibakteriális hatású oxazolidinon-származékok hatásának növelése argininszármazékokkal
WO2000027337A3 (fr) Procede de photostabilisation de derives de d,3,5-triazine
HUP0402643A2 (hu) 3,4-Dihidro-1H-izokinolin-2-il-származékok, eljárás az előállításukra és az ezeket tartalmazó gyógyszerkészítmények
AU558461B2 (en) Carbamyloxybenzhyrol derivatives
IT1255207B (it) Composizioni farmaceutuche ad attivita' antiaggregante e vasodilatatrice
CA2098821A1 (en) Benzodioxane derivatives
PT1206448E (pt) Novos analogos de vitamina d
NO994107D0 (no) Preparater for behandling eller forhindring av prostatakreft
HUP0301561A2 (hu) Triazintrion-szulfoxidok alkalmazása kokcidiózis elleni készítmények elżállítására
CA2027542A1 (en) Uv-absorbing cyclic enaminoketones
DK0561927T3 (da) Farmaceutiske præparater til behandling af maligne B-celle-affektioner
AU646260B2 (en) N-sulfonylbenzotriazole microbicides

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 1395538

Country of ref document: EP