ATE453399T1 - Isolierte dipeptide mit ace-inhibitionseffekt - Google Patents
Isolierte dipeptide mit ace-inhibitionseffektInfo
- Publication number
- ATE453399T1 ATE453399T1 AT05104422T AT05104422T ATE453399T1 AT E453399 T1 ATE453399 T1 AT E453399T1 AT 05104422 T AT05104422 T AT 05104422T AT 05104422 T AT05104422 T AT 05104422T AT E453399 T1 ATE453399 T1 AT E453399T1
- Authority
- AT
- Austria
- Prior art keywords
- isolated
- dipeptides
- inhibition effect
- ace inhibition
- val
- Prior art date
Links
- 230000000694 effects Effects 0.000 title abstract 2
- 108010016626 Dipeptides Proteins 0.000 title 1
- 230000005764 inhibitory process Effects 0.000 title 1
- BCXBIONYYJCSDF-CIUDSAMLSA-N Ile-Val Chemical compound CC[C@H](C)[C@H](N)C(=O)N[C@@H](C(C)C)C(O)=O BCXBIONYYJCSDF-CIUDSAMLSA-N 0.000 abstract 2
- MDSUKZSLOATHMH-IUCAKERBSA-N Leu-Val Chemical compound CC(C)C[C@H]([NH3+])C(=O)N[C@@H](C(C)C)C([O-])=O MDSUKZSLOATHMH-IUCAKERBSA-N 0.000 abstract 2
- MDSUKZSLOATHMH-UHFFFAOYSA-N N-L-leucyl-L-valine Natural products CC(C)CC(N)C(=O)NC(C(C)C)C(O)=O MDSUKZSLOATHMH-UHFFFAOYSA-N 0.000 abstract 2
- 108010078274 isoleucylvaline Proteins 0.000 abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 2
- 229940044094 angiotensin-converting-enzyme inhibitor Drugs 0.000 abstract 1
- 230000003276 anti-hypertensive effect Effects 0.000 abstract 1
- 235000013376 functional food Nutrition 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/05—Dipeptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/005—Enzyme inhibitors
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP05104422A EP1726659B1 (de) | 2005-05-24 | 2005-05-24 | Isolierte Dipeptide mit ACE-Inhibitionseffekt |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE453399T1 true ATE453399T1 (de) | 2010-01-15 |
Family
ID=35589590
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT05104422T ATE453399T1 (de) | 2005-05-24 | 2005-05-24 | Isolierte dipeptide mit ace-inhibitionseffekt |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20080207529A1 (de) |
| EP (2) | EP1726659B1 (de) |
| CN (1) | CN101180401A (de) |
| AT (1) | ATE453399T1 (de) |
| DE (1) | DE602005018612D1 (de) |
| WO (1) | WO2006125441A1 (de) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1907412B1 (de) * | 2005-06-30 | 2012-04-11 | Campina Nederland Holding B.V. | Das angiotensin-converting enzyme inhibierende peptide |
| ATE493999T1 (de) * | 2008-09-09 | 2011-01-15 | Unilever Nv | Nahrungsmittel enthaltend dipeptide mit blutdrucksenkenden eigenschaften. |
| CN110655553B (zh) * | 2019-10-10 | 2023-02-21 | 河南省农业科学院 | 一种芝麻来源的ace抑制肽、制备方法及其在制备降血压药物方面的应用 |
| CN112961212B (zh) * | 2021-02-01 | 2024-03-29 | 河南省农业科学院农副产品加工研究中心 | 一类ace抑制肽及其制备方法和应用 |
| CN114149485B (zh) * | 2021-05-28 | 2023-06-13 | 中国科学院大连化学物理研究所 | 一种抗菌肽mamp-02及其应用 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5243027A (en) * | 1990-02-26 | 1993-09-07 | Unitika, Ltd. | Method of preparing angiotensin converting enzyme inhibitors |
| JP4633876B2 (ja) * | 1999-11-11 | 2011-02-16 | カルピス株式会社 | トリペプチドの製造方法 |
| EP1529114A1 (de) | 2002-08-09 | 2005-05-11 | Chr. Hansen A/S | Verfahren für die herstellung von peptiden mit blutdrucksenkenden eigenschaften |
| TWI411441B (zh) * | 2003-03-18 | 2013-10-11 | Suntory Holdings Ltd | 血管收縮素轉化酶抑制性肽類 |
-
2005
- 2005-05-24 AT AT05104422T patent/ATE453399T1/de not_active IP Right Cessation
- 2005-05-24 EP EP05104422A patent/EP1726659B1/de not_active Expired - Lifetime
- 2005-05-24 DE DE602005018612T patent/DE602005018612D1/de not_active Expired - Lifetime
-
2006
- 2006-05-24 EP EP06722958A patent/EP1888762A1/de not_active Withdrawn
- 2006-05-24 US US11/913,092 patent/US20080207529A1/en not_active Abandoned
- 2006-05-24 CN CNA2006800176801A patent/CN101180401A/zh active Pending
- 2006-05-24 WO PCT/DK2006/000288 patent/WO2006125441A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| US20080207529A1 (en) | 2008-08-28 |
| EP1726659B1 (de) | 2009-12-30 |
| WO2006125441A1 (en) | 2006-11-30 |
| DE602005018612D1 (de) | 2010-02-11 |
| EP1888762A1 (de) | 2008-02-20 |
| CN101180401A (zh) | 2008-05-14 |
| EP1726659A1 (de) | 2006-11-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |