ATE449173T1 - 32144, eine humane fettsäureamid-hydrolase und deren verwendungen - Google Patents
32144, eine humane fettsäureamid-hydrolase und deren verwendungenInfo
- Publication number
- ATE449173T1 ATE449173T1 AT01979491T AT01979491T ATE449173T1 AT E449173 T1 ATE449173 T1 AT E449173T1 AT 01979491 T AT01979491 T AT 01979491T AT 01979491 T AT01979491 T AT 01979491T AT E449173 T1 ATE449173 T1 AT E449173T1
- Authority
- AT
- Austria
- Prior art keywords
- nucleic acid
- fatty acid
- acid amide
- acid molecules
- amide hydrolase
- Prior art date
Links
- 108010046094 fatty-acid amide hydrolase Proteins 0.000 title abstract 2
- 102000039446 nucleic acids Human genes 0.000 abstract 4
- 108020004707 nucleic acids Proteins 0.000 abstract 4
- 150000007523 nucleic acids Chemical class 0.000 abstract 4
- 239000013604 expression vector Substances 0.000 abstract 2
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 102100029111 Fatty-acid amide hydrolase 1 Human genes 0.000 abstract 1
- 241001465754 Metazoa Species 0.000 abstract 1
- 230000000692 anti-sense effect Effects 0.000 abstract 1
- 230000000890 antigenic effect Effects 0.000 abstract 1
- 238000002405 diagnostic procedure Methods 0.000 abstract 1
- 108020001507 fusion proteins Proteins 0.000 abstract 1
- 102000037865 fusion proteins Human genes 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 238000003259 recombinant expression Methods 0.000 abstract 1
- 230000009261 transgenic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
- C12N9/80—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in linear amides (3.5.1)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Biomedical Technology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US23805400P | 2000-10-05 | 2000-10-05 | |
| PCT/US2001/031188 WO2002029057A2 (en) | 2000-10-05 | 2001-09-27 | 32144, a human fatty acid amide hydrolase and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE449173T1 true ATE449173T1 (de) | 2009-12-15 |
Family
ID=22896307
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT01979491T ATE449173T1 (de) | 2000-10-05 | 2001-09-27 | 32144, eine humane fettsäureamid-hydrolase und deren verwendungen |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20020164769A1 (de) |
| EP (1) | EP1332214B1 (de) |
| AT (1) | ATE449173T1 (de) |
| AU (1) | AU2002211446A1 (de) |
| DE (1) | DE60140559D1 (de) |
| ES (1) | ES2335478T3 (de) |
| WO (1) | WO2002029057A2 (de) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JO3598B1 (ar) | 2006-10-10 | 2020-07-05 | Infinity Discovery Inc | الاحماض والاسترات البورونية كمثبطات اميد هيدروليز الحامض الدهني |
| JP5637982B2 (ja) * | 2008-04-09 | 2014-12-10 | インフィニティー ファーマシューティカルズ， インコーポレイテッド | 脂肪酸アミド加水分解酵素の阻害剤 |
| US8207226B1 (en) * | 2008-06-03 | 2012-06-26 | Alcon Research, Ltd. | Use of FAAH antagonists for treating dry eye and ocular pain |
| EP2416660B1 (de) | 2009-04-07 | 2014-07-02 | Infinity Pharmaceuticals, Inc. | Fettsäureamidhydrolase-hemmer |
| JP2012523425A (ja) | 2009-04-07 | 2012-10-04 | インフイニトイ プハルマセウトイカルス インコーポレイテッド | 脂肪酸アミドヒドロラーゼの阻害薬 |
| US9062116B2 (en) | 2009-04-23 | 2015-06-23 | Infinity Pharmaceuticals, Inc. | Anti-fatty acid amide hydrolase-2 antibodies and uses thereof |
| US8765735B2 (en) * | 2009-05-18 | 2014-07-01 | Infinity Pharmaceuticals, Inc. | Isoxazolines as inhibitors of fatty acid amide hydrolase |
| US9149465B2 (en) * | 2009-05-18 | 2015-10-06 | Infinity Pharmaceuticals, Inc. | Isoxazolines as inhibitors of fatty acid amide hydrolase |
| US8927551B2 (en) * | 2009-05-18 | 2015-01-06 | Infinity Pharmaceuticals, Inc. | Isoxazolines as inhibitors of fatty acid amide hydrolase |
| KR101888026B1 (ko) | 2010-02-03 | 2018-08-13 | 인피니티 파마슈티컬스, 인코포레이티드 | 지방산 아미드 하이드롤라제 저해제 |
| US11078528B2 (en) | 2015-10-12 | 2021-08-03 | Advanced Cell Diagnostics, Inc. | In situ detection of nucleotide variants in high noise samples, and compositions and methods related thereto |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2003518920A (ja) * | 1999-07-02 | 2003-06-17 | カイロン コーポレイション | 新規なヒト遺伝子および遺伝子発現産物 |
| WO2001051628A2 (en) * | 2000-01-14 | 2001-07-19 | Millennium Pharmaceuticals, Inc. | Genes compositions, kits, and methods for identification, assessment, prevention, and therapy of breast cancer |
| AU2001257427A1 (en) * | 2000-04-28 | 2001-11-12 | Incyte Genomics, Inc. | Rna metabolism proteins |
-
2001
- 2001-09-27 AU AU2002211446A patent/AU2002211446A1/en not_active Abandoned
- 2001-09-27 ES ES01979491T patent/ES2335478T3/es not_active Expired - Lifetime
- 2001-09-27 US US09/966,614 patent/US20020164769A1/en not_active Abandoned
- 2001-09-27 AT AT01979491T patent/ATE449173T1/de not_active IP Right Cessation
- 2001-09-27 WO PCT/US2001/031188 patent/WO2002029057A2/en not_active Ceased
- 2001-09-27 DE DE60140559T patent/DE60140559D1/de not_active Expired - Lifetime
- 2001-09-27 EP EP01979491A patent/EP1332214B1/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| WO2002029057A2 (en) | 2002-04-11 |
| AU2002211446A1 (en) | 2002-04-15 |
| DE60140559D1 (de) | 2009-12-31 |
| WO2002029057A3 (en) | 2003-01-23 |
| EP1332214A2 (de) | 2003-08-06 |
| US20020164769A1 (en) | 2002-11-07 |
| EP1332214B1 (de) | 2009-11-18 |
| ES2335478T3 (es) | 2010-03-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |