ATE445404T1 - Verwendung von adefovir oder tenofovir zur hemmung von mmtv-artigen viren im zusammenhang mit brustkrebs und primärer biliärer zirrhose - Google Patents
Verwendung von adefovir oder tenofovir zur hemmung von mmtv-artigen viren im zusammenhang mit brustkrebs und primärer biliärer zirrhoseInfo
- Publication number
- ATE445404T1 ATE445404T1 AT05706024T AT05706024T ATE445404T1 AT E445404 T1 ATE445404 T1 AT E445404T1 AT 05706024 T AT05706024 T AT 05706024T AT 05706024 T AT05706024 T AT 05706024T AT E445404 T1 ATE445404 T1 AT E445404T1
- Authority
- AT
- Austria
- Prior art keywords
- adefovir
- tenofovir
- mmtv
- breast cancer
- inhibit
- Prior art date
Links
- WOZSCQDILHKSGG-UHFFFAOYSA-N adefovir depivoxil Chemical compound N1=CN=C2N(CCOCP(=O)(OCOC(=O)C(C)(C)C)OCOC(=O)C(C)(C)C)C=NC2=C1N WOZSCQDILHKSGG-UHFFFAOYSA-N 0.000 title abstract 3
- 229960004556 tenofovir Drugs 0.000 title abstract 3
- 206010006187 Breast cancer Diseases 0.000 title abstract 2
- 208000026310 Breast neoplasm Diseases 0.000 title abstract 2
- 229960001997 adefovir Drugs 0.000 title abstract 2
- 208000008439 Biliary Liver Cirrhosis Diseases 0.000 title 1
- 208000033222 Biliary cirrhosis primary Diseases 0.000 title 1
- 208000012654 Primary biliary cholangitis Diseases 0.000 title 1
- 241000700605 Viruses Species 0.000 title 1
- SGOIRFVFHAKUTI-ZCFIWIBFSA-N tenofovir (anhydrous) Chemical compound N1=CN=C2N(C[C@@H](C)OCP(O)(O)=O)C=NC2=C1N SGOIRFVFHAKUTI-ZCFIWIBFSA-N 0.000 title 1
- VCMJCVGFSROFHV-WZGZYPNHSA-N tenofovir disoproxil fumarate Chemical compound OC(=O)\C=C\C(O)=O.N1=CN=C2N(C[C@@H](C)OCP(=O)(OCOC(=O)OC(C)C)OCOC(=O)OC(C)C)C=NC2=C1N VCMJCVGFSROFHV-WZGZYPNHSA-N 0.000 abstract 2
- MELHEUHXJKQZNC-UHFFFAOYSA-N 2-(6-aminopurin-9-yl)ethoxymethyl-[hydroxy(phosphonooxy)phosphoryl]oxyphosphinic acid Chemical compound NC1=NC=NC2=C1N=CN2CCOCP(O)(=O)OP(O)(=O)OP(O)(O)=O MELHEUHXJKQZNC-UHFFFAOYSA-N 0.000 abstract 1
- 241000713333 Mouse mammary tumor virus Species 0.000 abstract 1
- IACQCQDWSIQSRP-ZCFIWIBFSA-N [(2r)-1-(6-aminopurin-9-yl)propan-2-yl]oxymethyl-[hydroxy(phosphonooxy)phosphoryl]oxyphosphinic acid Chemical compound N1=CN=C2N(C[C@@H](C)OCP(O)(=O)OP(O)(=O)OP(O)(O)=O)C=NC2=C1N IACQCQDWSIQSRP-ZCFIWIBFSA-N 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 230000003389 potentiating effect Effects 0.000 abstract 1
- 241001430294 unidentified retrovirus Species 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/14—Drugs for genital or sexual disorders; Contraceptives for lactation disorders, e.g. galactorrhoea
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Virology (AREA)
- Gynecology & Obstetrics (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Pregnancy & Childbirth (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Gastroenterology & Hepatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US53806604P | 2004-01-21 | 2004-01-21 | |
| PCT/US2005/002043 WO2005072748A1 (en) | 2004-01-21 | 2005-01-21 | Use of adefovir or tenofovir for inhibiting mmtv-like viruses involved in breast cancer and primary biliary cirrhosis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE445404T1 true ATE445404T1 (de) | 2009-10-15 |
Family
ID=34825960
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT05706024T ATE445404T1 (de) | 2004-01-21 | 2005-01-21 | Verwendung von adefovir oder tenofovir zur hemmung von mmtv-artigen viren im zusammenhang mit brustkrebs und primärer biliärer zirrhose |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US20070281911A1 (enExample) |
| EP (1) | EP1732569B1 (enExample) |
| JP (1) | JP2007518815A (enExample) |
| AT (1) | ATE445404T1 (enExample) |
| AU (1) | AU2005209256B2 (enExample) |
| CA (1) | CA2553455A1 (enExample) |
| DE (1) | DE602005017131D1 (enExample) |
| ES (1) | ES2334149T3 (enExample) |
| NZ (1) | NZ548532A (enExample) |
| WO (1) | WO2005072748A1 (enExample) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1879657A2 (en) * | 2005-04-25 | 2008-01-23 | Institute Of Organic Chemistry And Biochemistry Of The Academy Of Sciences Of The Czech Republic | Use of compounds to enhance processivity of telomerase |
| RU2301088C2 (ru) * | 2005-09-01 | 2007-06-20 | Ростовский научно-исследовательский онкологический институт МЗ РФ | Способ лечения рецидива рака молочной железы |
| PL2020996T3 (pl) | 2006-05-16 | 2012-04-30 | Gilead Sciences Inc | Sposób i kompozycje do leczenia chorób nowotworowych układu krwiotwórczego |
| EP2486407B1 (en) * | 2009-10-05 | 2016-02-10 | Ambergen Inc. | A method for diagnosing primary biliary cirrhosis (pbc) using novel autoantigens |
| US20140031250A1 (en) | 2010-10-07 | 2014-01-30 | David Tsai Ting | Biomarkers of Cancer |
| CA2856722C (en) | 2011-11-30 | 2022-11-22 | Emory University | Antiviral jak inhibitors useful in treating or preventing retroviral and other viral infections |
| EP3760208B1 (en) | 2014-06-25 | 2024-05-29 | The General Hospital Corporation | Targeting human satellite ii (hsatii) |
| CN118286245A (zh) | 2014-12-26 | 2024-07-05 | 埃莫里大学 | N4-羟基胞苷和衍生物及与其相关的抗病毒用途 |
| GB201509431D0 (en) * | 2015-06-01 | 2015-07-15 | Equigerminal Sa | Antiviral composition |
| US11331331B2 (en) | 2017-12-07 | 2022-05-17 | Emory University | N4-hydroxycytidine and derivatives and anti-viral uses related thereto |
| KR102196711B1 (ko) * | 2018-08-30 | 2020-12-30 | 가톨릭대학교 산학협력단 | 테노포비르 디소프록실 푸마르산을 유효성분으로 함유하는, 간섬유증 예방 또는 치료용 약학적 조성물 |
| WO2020171225A1 (ja) * | 2019-02-22 | 2020-08-27 | 一素 村田 | ｍＴＯＲ阻害剤 |
| US12029783B2 (en) | 2019-07-02 | 2024-07-09 | Virago Vax Inc. | Mammary tumor virus vaccine |
| US12016844B2 (en) | 2019-07-02 | 2024-06-25 | Virago Vax Inc. | Mammary tumor virus suppression |
| WO2021003421A1 (en) * | 2019-07-02 | 2021-01-07 | Virago Vax Inc. | Mammary tumor virus suppression |
| AU2023236711A1 (en) | 2022-03-15 | 2024-10-03 | Rome Therapeutics, Inc. | Compounds and methods for treating disease |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE60038889D1 (de) * | 1999-06-01 | 2008-06-26 | Ochsner Med Found Alton | Identifizierung eines neuartigen retrovirus welcher mit primärer leberzirrhose sowie autoimmunerkrankungen einhergeht |
| MXPA01013388A (es) * | 1999-06-30 | 2002-07-02 | Tulane University Medical Ct | Retrovirus endogeno humano en cancer de pecho. |
| DK1301519T4 (da) * | 2000-07-21 | 2021-12-20 | Gilead Sciences Inc | Prodrugs af phosphonatnukleotidanaloger og fremgangsmåder til udvælgelse og fremstilling heraf |
| IL164809A0 (en) * | 2002-05-13 | 2005-12-18 | Metabasis Therapeutics Inc | Novel phosphonic acid basdrugs of pmea and its analogues |
-
2005
- 2005-01-21 WO PCT/US2005/002043 patent/WO2005072748A1/en not_active Ceased
- 2005-01-21 US US10/586,627 patent/US20070281911A1/en not_active Abandoned
- 2005-01-21 DE DE602005017131T patent/DE602005017131D1/de not_active Expired - Lifetime
- 2005-01-21 CA CA002553455A patent/CA2553455A1/en not_active Abandoned
- 2005-01-21 NZ NZ548532A patent/NZ548532A/en unknown
- 2005-01-21 ES ES05706024T patent/ES2334149T3/es not_active Expired - Lifetime
- 2005-01-21 EP EP05706024A patent/EP1732569B1/en not_active Expired - Lifetime
- 2005-01-21 JP JP2006551327A patent/JP2007518815A/ja active Pending
- 2005-01-21 AT AT05706024T patent/ATE445404T1/de not_active IP Right Cessation
- 2005-01-21 AU AU2005209256A patent/AU2005209256B2/en not_active Ceased
- 2005-01-21 US US11/040,929 patent/US20050239753A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20050239753A1 (en) | 2005-10-27 |
| HK1099228A1 (en) | 2007-08-10 |
| US20070281911A1 (en) | 2007-12-06 |
| WO2005072748A1 (en) | 2005-08-11 |
| ES2334149T3 (es) | 2010-03-05 |
| CA2553455A1 (en) | 2005-08-11 |
| AU2005209256A1 (en) | 2005-08-11 |
| AU2005209256B2 (en) | 2010-11-18 |
| DE602005017131D1 (de) | 2009-11-26 |
| EP1732569B1 (en) | 2009-10-14 |
| JP2007518815A (ja) | 2007-07-12 |
| EP1732569A1 (en) | 2006-12-20 |
| NZ548532A (en) | 2009-09-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |