ATE445404T1 - Verwendung von adefovir oder tenofovir zur hemmung von mmtv-artigen viren im zusammenhang mit brustkrebs und primärer biliärer zirrhose - Google Patents
Verwendung von adefovir oder tenofovir zur hemmung von mmtv-artigen viren im zusammenhang mit brustkrebs und primärer biliärer zirrhoseInfo
- Publication number
- ATE445404T1 ATE445404T1 AT05706024T AT05706024T ATE445404T1 AT E445404 T1 ATE445404 T1 AT E445404T1 AT 05706024 T AT05706024 T AT 05706024T AT 05706024 T AT05706024 T AT 05706024T AT E445404 T1 ATE445404 T1 AT E445404T1
- Authority
- AT
- Austria
- Prior art keywords
- adefovir
- tenofovir
- mmtv
- breast cancer
- inhibit
- Prior art date
Links
- WOZSCQDILHKSGG-UHFFFAOYSA-N adefovir depivoxil Chemical compound N1=CN=C2N(CCOCP(=O)(OCOC(=O)C(C)(C)C)OCOC(=O)C(C)(C)C)C=NC2=C1N WOZSCQDILHKSGG-UHFFFAOYSA-N 0.000 title abstract 3
- 229960004556 tenofovir Drugs 0.000 title abstract 3
- 206010006187 Breast cancer Diseases 0.000 title abstract 2
- 208000026310 Breast neoplasm Diseases 0.000 title abstract 2
- 229960001997 adefovir Drugs 0.000 title abstract 2
- 208000008439 Biliary Liver Cirrhosis Diseases 0.000 title 1
- 208000033222 Biliary cirrhosis primary Diseases 0.000 title 1
- 208000012654 Primary biliary cholangitis Diseases 0.000 title 1
- 241000700605 Viruses Species 0.000 title 1
- SGOIRFVFHAKUTI-ZCFIWIBFSA-N tenofovir (anhydrous) Chemical compound N1=CN=C2N(C[C@@H](C)OCP(O)(O)=O)C=NC2=C1N SGOIRFVFHAKUTI-ZCFIWIBFSA-N 0.000 title 1
- VCMJCVGFSROFHV-WZGZYPNHSA-N tenofovir disoproxil fumarate Chemical compound OC(=O)\C=C\C(O)=O.N1=CN=C2N(C[C@@H](C)OCP(=O)(OCOC(=O)OC(C)C)OCOC(=O)OC(C)C)C=NC2=C1N VCMJCVGFSROFHV-WZGZYPNHSA-N 0.000 abstract 2
- MELHEUHXJKQZNC-UHFFFAOYSA-N 2-(6-aminopurin-9-yl)ethoxymethyl-[hydroxy(phosphonooxy)phosphoryl]oxyphosphinic acid Chemical compound NC1=NC=NC2=C1N=CN2CCOCP(O)(=O)OP(O)(=O)OP(O)(O)=O MELHEUHXJKQZNC-UHFFFAOYSA-N 0.000 abstract 1
- 241000713333 Mouse mammary tumor virus Species 0.000 abstract 1
- IACQCQDWSIQSRP-ZCFIWIBFSA-N [(2r)-1-(6-aminopurin-9-yl)propan-2-yl]oxymethyl-[hydroxy(phosphonooxy)phosphoryl]oxyphosphinic acid Chemical compound N1=CN=C2N(C[C@@H](C)OCP(O)(=O)OP(O)(=O)OP(O)(O)=O)C=NC2=C1N IACQCQDWSIQSRP-ZCFIWIBFSA-N 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 230000003389 potentiating effect Effects 0.000 abstract 1
- 241001430294 unidentified retrovirus Species 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/14—Drugs for genital or sexual disorders; Contraceptives for lactation disorders, e.g. galactorrhoea
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Virology (AREA)
- Gynecology & Obstetrics (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Pregnancy & Childbirth (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Gastroenterology & Hepatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US53806604P | 2004-01-21 | 2004-01-21 | |
| PCT/US2005/002043 WO2005072748A1 (en) | 2004-01-21 | 2005-01-21 | Use of adefovir or tenofovir for inhibiting mmtv-like viruses involved in breast cancer and primary biliary cirrhosis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE445404T1 true ATE445404T1 (de) | 2009-10-15 |
Family
ID=34825960
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT05706024T ATE445404T1 (de) | 2004-01-21 | 2005-01-21 | Verwendung von adefovir oder tenofovir zur hemmung von mmtv-artigen viren im zusammenhang mit brustkrebs und primärer biliärer zirrhose |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US20070281911A1 (de) |
| EP (1) | EP1732569B1 (de) |
| JP (1) | JP2007518815A (de) |
| AT (1) | ATE445404T1 (de) |
| AU (1) | AU2005209256B2 (de) |
| CA (1) | CA2553455A1 (de) |
| DE (1) | DE602005017131D1 (de) |
| ES (1) | ES2334149T3 (de) |
| NZ (1) | NZ548532A (de) |
| WO (1) | WO2005072748A1 (de) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2606399A1 (en) * | 2005-04-25 | 2006-11-02 | Institute Of Organic Chemistry And Biochemistry Of The Academy Of Scienc Es Of The Czech Republic | Use of compounds to enhance processivity of telomerase |
| RU2301088C2 (ru) * | 2005-09-01 | 2007-06-20 | Ростовский научно-исследовательский онкологический институт МЗ РФ | Способ лечения рецидива рака молочной железы |
| KR101424832B1 (ko) | 2006-05-16 | 2014-08-06 | 길리애드 사이언시즈, 인코포레이티드 | 악성 혈액 종양 치료 방법 및 악성 혈액 종양 치료용 조성물 |
| ES2566762T3 (es) * | 2009-10-05 | 2016-04-15 | Ambergen Inc. | Un procedimiento de diagnóstico de cirrosis biliar primaria (PBC) usando nuevos autoantígenos |
| CN103517990A (zh) | 2010-10-07 | 2014-01-15 | 通用医疗公司 | 癌症生物标志物 |
| CA3131037A1 (en) | 2011-11-30 | 2013-06-06 | Emory University | Antiviral jak inhibitors useful in treating or preventing retroviral and other viral infections |
| US10301624B2 (en) | 2014-06-25 | 2019-05-28 | The General Hospital Corporation | Targeting human satellite II (HSATII) |
| JP7381190B2 (ja) | 2014-12-26 | 2023-11-15 | エモリー・ユニバーシテイ | Ｎ４－ヒドロキシシチジン及び誘導体並びにそれに関連する抗ウイルス用途 |
| GB201509431D0 (en) * | 2015-06-01 | 2015-07-15 | Equigerminal Sa | Antiviral composition |
| KR102626210B1 (ko) | 2017-12-07 | 2024-01-18 | 에모리 유니버시티 | N4-하이드록시사이티딘 및 유도체 및 이와 관련된 항-바이러스 용도 |
| KR102196711B1 (ko) * | 2018-08-30 | 2020-12-30 | 가톨릭대학교 산학협력단 | 테노포비르 디소프록실 푸마르산을 유효성분으로 함유하는, 간섬유증 예방 또는 치료용 약학적 조성물 |
| WO2020171225A1 (ja) * | 2019-02-22 | 2020-08-27 | 一素 村田 | ｍＴＯＲ阻害剤 |
| EP3993873A4 (de) * | 2019-07-02 | 2023-09-20 | Virago Vax Inc. | Unterdrückung von brusttumoren |
| US12016844B2 (en) | 2019-07-02 | 2024-06-25 | Virago Vax Inc. | Mammary tumor virus suppression |
| US12029783B2 (en) | 2019-07-02 | 2024-07-09 | Virago Vax Inc. | Mammary tumor virus vaccine |
| JP2025509635A (ja) | 2022-03-15 | 2025-04-11 | ローム・セラピューティクス・インコーポレイテッド | 疾患を治療するための化合物及び方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE395432T1 (de) * | 1999-06-01 | 2008-05-15 | Ochsner Med Found Alton | Identifizierung eines neuartigen retrovirus welcher mit primärer leberzirrhose sowie autoimmunerkrankungen einhergeht |
| DK1190055T3 (da) * | 1999-06-30 | 2008-09-22 | Univ Tulane | Human endogen retrovirus |
| MXPA03000587A (es) * | 2000-07-21 | 2004-04-05 | Gilead Sciences Inc | Profarmacos de analogos de nucleotido de fosfonato y metodos para seleccionar y elaborar los mismos. |
| IL164809A0 (en) * | 2002-05-13 | 2005-12-18 | Metabasis Therapeutics Inc | Novel phosphonic acid basdrugs of pmea and its analogues |
-
2005
- 2005-01-21 AU AU2005209256A patent/AU2005209256B2/en not_active Ceased
- 2005-01-21 ES ES05706024T patent/ES2334149T3/es not_active Expired - Lifetime
- 2005-01-21 CA CA002553455A patent/CA2553455A1/en not_active Abandoned
- 2005-01-21 WO PCT/US2005/002043 patent/WO2005072748A1/en not_active Ceased
- 2005-01-21 JP JP2006551327A patent/JP2007518815A/ja active Pending
- 2005-01-21 US US10/586,627 patent/US20070281911A1/en not_active Abandoned
- 2005-01-21 US US11/040,929 patent/US20050239753A1/en not_active Abandoned
- 2005-01-21 AT AT05706024T patent/ATE445404T1/de not_active IP Right Cessation
- 2005-01-21 NZ NZ548532A patent/NZ548532A/en unknown
- 2005-01-21 EP EP05706024A patent/EP1732569B1/de not_active Expired - Lifetime
- 2005-01-21 DE DE602005017131T patent/DE602005017131D1/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| US20070281911A1 (en) | 2007-12-06 |
| EP1732569A1 (de) | 2006-12-20 |
| DE602005017131D1 (de) | 2009-11-26 |
| CA2553455A1 (en) | 2005-08-11 |
| ES2334149T3 (es) | 2010-03-05 |
| US20050239753A1 (en) | 2005-10-27 |
| AU2005209256B2 (en) | 2010-11-18 |
| NZ548532A (en) | 2009-09-25 |
| EP1732569B1 (de) | 2009-10-14 |
| AU2005209256A1 (en) | 2005-08-11 |
| JP2007518815A (ja) | 2007-07-12 |
| HK1099228A1 (en) | 2007-08-10 |
| WO2005072748A1 (en) | 2005-08-11 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE445404T1 (de) | Verwendung von adefovir oder tenofovir zur hemmung von mmtv-artigen viren im zusammenhang mit brustkrebs und primärer biliärer zirrhose | |
| PH12020551244A1 (en) | Pd-1/pd-l1 inhibitors | |
| JOP20220024A1 (ar) | مركبات مساعدة لـ gipr | |
| BR112023000205A2 (pt) | Misturas fungicidas | |
| CR20190478A (es) | Inhibidores de pd-1/pd-l1 | |
| CL2004002050A1 (es) | Compuestos derivados de piridinonas sustituidas; su uso en el tratamiento de afecciones causadas o exacerbadas por actividad p38 map kinasa y/o tnf no regulada, tales como inflamaciones, tumores, sida y otros. | |
| EA201000777A1 (ru) | Ингибиторы репликации вируса иммунодефицита человека | |
| ITMI20052171A1 (it) | Composti e-amminocarbonil bicicloepten pirimidindiamminici stereoisomericamente arricchiti e loro uso | |
| DK1866324T3 (da) | Phosphoramidatderivater af nukleosidforbindelser til anvendelse i behandlingen af cancer | |
| ZA200709481B (en) | Diaryl-purine, azapurines and -deazapurines as non-nucleoside reverse transcriptase inhibitors for treatment of HIV | |
| IS7997A (is) | Granisetron lyfjaplástur | |
| NO20064547L (no) | Fremgangsmater for behandling av HIV infeksjon | |
| MY204310A (en) | Mast cell stabilizers for treatment of hypercytokinemia and viral infection | |
| CO2022000481A2 (es) | Inhibidores de enzimas | |
| EA202191257A1 (ru) | Противораковая терапия на основе иммуноцитов, связывающих liv1 | |
| MX339783B (es) | Cuchilla doble para segueta manual y metodo para su manufactura. | |
| CY1109440T1 (el) | Φωσφοϊνδολες ως αναστολεις hiv | |
| BRPI0515319A (pt) | análogos de quinolona | |
| MX2022000811A (es) | Inhibidores de enzimas. | |
| ATE400319T1 (de) | Tetrahydropyridothiophene | |
| ATE397000T1 (de) | Tetrahydropyridothiophenen zur verwendung in der behandlung von krebs | |
| UY29417A1 (es) | Agentes endoparasiticidas | |
| PH12019502290A1 (en) | Therapeutic agent for blood cancer | |
| UA117563C2 (uk) | Композиція для лікування або профілактики хвороби, асоційованої з інфекцією впл | |
| CL2008001819A1 (es) | Compuestos derivados de fenoxi-fluorobenceno sustituido; composicion farmaceutica; y uso en el tratamiento de enfermedades virales tales como vih y sida. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |