ATE444304T1 - Verfahren zur herstellung von tripeptid- zwischenprodukten zur herstellung von lhrh- antagonisten - Google Patents
Verfahren zur herstellung von tripeptid- zwischenprodukten zur herstellung von lhrh- antagonistenInfo
- Publication number
- ATE444304T1 ATE444304T1 AT05004940T AT05004940T ATE444304T1 AT E444304 T1 ATE444304 T1 AT E444304T1 AT 05004940 T AT05004940 T AT 05004940T AT 05004940 T AT05004940 T AT 05004940T AT E444304 T1 ATE444304 T1 AT E444304T1
- Authority
- AT
- Austria
- Prior art keywords
- producing
- intermediate products
- lhrh antagonists
- tripeptide intermediate
- tripeptide
- Prior art date
Links
- 229940124041 Luteinizing hormone releasing hormone (LHRH) antagonist Drugs 0.000 title abstract 2
- 239000013067 intermediate product Substances 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 238000007796 conventional method Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/23—Luteinising hormone-releasing hormone [LHRH]; Related peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0827—Tripeptides containing heteroatoms different from O, S, or N
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Life Sciences & Earth Sciences (AREA)
- Endocrinology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2004066256A JP4407322B2 (ja) | 2004-03-09 | 2004-03-09 | ペプチドの製造方法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE444304T1 true ATE444304T1 (de) | 2009-10-15 |
Family
ID=34909384
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT05004940T ATE444304T1 (de) | 2004-03-09 | 2005-03-07 | Verfahren zur herstellung von tripeptid- zwischenprodukten zur herstellung von lhrh- antagonisten |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US7569548B2 (enExample) |
| EP (1) | EP1584625B1 (enExample) |
| JP (1) | JP4407322B2 (enExample) |
| AT (1) | ATE444304T1 (enExample) |
| DE (1) | DE602005016857D1 (enExample) |
| DK (1) | DK1584625T3 (enExample) |
| ES (1) | ES2332655T3 (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4407322B2 (ja) * | 2004-03-09 | 2010-02-03 | 味の素株式会社 | ペプチドの製造方法 |
| CN103524599B (zh) * | 2012-07-05 | 2016-04-20 | 中国人民解放军军事医学科学院毒物药物研究所 | 环肽lhrh拮抗剂衍生物及其药物用途 |
| US12012467B2 (en) | 2017-03-28 | 2024-06-18 | Regents Of The University Of Michigan | Small molecule DCN1 inhibitors and therapeutic methods using the same |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2012488A (en) * | 1987-07-31 | 1989-02-02 | Syntex (U.S.A.) Inc. | Combination therapy with lhrh antagonist analogs and 19nor progestational steroids |
| WO1989007450A1 (en) * | 1988-02-10 | 1989-08-24 | Abbott Laboratories | Lhrh analogs |
| US5212288A (en) * | 1990-02-20 | 1993-05-18 | Syntex (U.S.A.) Inc. | Temporary minimal protection synthesis of serine-containing polypeptides |
| JPH05508859A (ja) * | 1990-07-24 | 1993-12-09 | イーストマン コダック カンパニー | ペプチド合成方法 |
| US5843901A (en) * | 1995-06-07 | 1998-12-01 | Advanced Research & Technology Institute | LHRH antagonist peptides |
| US5710247A (en) * | 1996-03-19 | 1998-01-20 | Abbott Laboratories | Process and intermediates for the synthesis of LHRH antagonists |
| US6013764A (en) | 1996-07-17 | 2000-01-11 | Ortho Pharmaceutical Corp. | Liquid phase peptide synthesis of KL-4 pulmonary surfactant |
| AU1590699A (en) * | 1997-11-20 | 1999-06-15 | Ortho-Mcneil Pharmaceutical, Inc. | Liquid phase process for the preparation of gnrh peptides |
| SE0104463D0 (sv) * | 2001-12-29 | 2001-12-29 | Carlbiotech Ltd As | Mellanprodukter för syntes af LHRH-antagonister, sätt att framställa dem och sätt för framställning av LHRH-antagonister |
| JP4407322B2 (ja) * | 2004-03-09 | 2010-02-03 | 味の素株式会社 | ペプチドの製造方法 |
-
2004
- 2004-03-09 JP JP2004066256A patent/JP4407322B2/ja not_active Expired - Fee Related
-
2005
- 2005-03-07 ES ES05004940T patent/ES2332655T3/es not_active Expired - Lifetime
- 2005-03-07 DE DE602005016857T patent/DE602005016857D1/de active Active
- 2005-03-07 AT AT05004940T patent/ATE444304T1/de not_active IP Right Cessation
- 2005-03-07 DK DK05004940.2T patent/DK1584625T3/da active
- 2005-03-07 EP EP05004940A patent/EP1584625B1/en not_active Expired - Lifetime
- 2005-03-08 US US11/073,729 patent/US7569548B2/en not_active Expired - Fee Related
-
2009
- 2009-05-21 US US12/470,010 patent/US7915224B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US7569548B2 (en) | 2009-08-04 |
| US7915224B2 (en) | 2011-03-29 |
| EP1584625A1 (en) | 2005-10-12 |
| ES2332655T3 (es) | 2010-02-10 |
| JP2005255556A (ja) | 2005-09-22 |
| DK1584625T3 (da) | 2010-02-01 |
| US20050203028A1 (en) | 2005-09-15 |
| US20090234098A1 (en) | 2009-09-17 |
| JP4407322B2 (ja) | 2010-02-03 |
| EP1584625B1 (en) | 2009-09-30 |
| DE602005016857D1 (de) | 2009-11-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |