ATE443065T1 - Benzodiazepinderivate und anwendungen davon auf dem medizinischen gebiet - Google Patents

Benzodiazepinderivate und anwendungen davon auf dem medizinischen gebiet

Info

Publication number
ATE443065T1
ATE443065T1 AT06756301T AT06756301T ATE443065T1 AT E443065 T1 ATE443065 T1 AT E443065T1 AT 06756301 T AT06756301 T AT 06756301T AT 06756301 T AT06756301 T AT 06756301T AT E443065 T1 ATE443065 T1 AT E443065T1
Authority
AT
Austria
Prior art keywords
sub
alkyl
alkynyl
alkenyl
alkoxy
Prior art date
Application number
AT06756301T
Other languages
English (en)
Inventor
Romano Silvestri
Gabriella Marfe
Elisabetta Abruzzese
Gianfranco Catalano
Stefano Carla Di
Ettore Novellino
Salimei Paola Sinibaldi
Regina Giuseppe La
Antonio Lavecchia
Original Assignee
Uni Degli Studi Di Roma S Tor
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Uni Degli Studi Di Roma S Tor filed Critical Uni Degli Studi Di Roma S Tor
Application granted granted Critical
Publication of ATE443065T1 publication Critical patent/ATE443065T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
AT06756301T 2005-08-03 2006-05-26 Benzodiazepinderivate und anwendungen davon auf dem medizinischen gebiet ATE443065T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT000416A ITRM20050416A1 (it) 2005-08-03 2005-08-03 Derivati delle benzodiazepine e loro usi in campo medico.
PCT/IT2006/000401 WO2007015280A1 (en) 2005-08-03 2006-05-26 Benzodiazepine derivatives and uses thereof in medical field

Publications (1)

Publication Number Publication Date
ATE443065T1 true ATE443065T1 (de) 2009-10-15

Family

ID=36889076

Family Applications (1)

Application Number Title Priority Date Filing Date
AT06756301T ATE443065T1 (de) 2005-08-03 2006-05-26 Benzodiazepinderivate und anwendungen davon auf dem medizinischen gebiet

Country Status (6)

Country Link
US (1) US20080249080A1 (de)
EP (1) EP1910383B1 (de)
AT (1) ATE443065T1 (de)
DE (1) DE602006009276D1 (de)
IT (1) ITRM20050416A1 (de)
WO (1) WO2007015280A1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL271761B (en) 2009-02-05 2022-09-01 Immunogen Inc (12as)-8-methoxy-9-benzyloxy-11,12,12a,13-tetrahydro-6h-indolo[2,1-c][1,4]benzodiazepine-6-one, 4-benzyloxy-5-methoxy -2-nitrobenzoic acid and a process for their preparation
RU2748733C2 (ru) 2011-02-15 2021-05-31 Иммуноджен, Инк. Цитотоксические производные бензодиазепина
EP2887965A1 (de) 2012-08-22 2015-07-01 ImmunoGen, Inc. Zytotoxische benzodiazepin-derivate
WO2016036804A1 (en) 2014-09-03 2016-03-10 Immunogen, Inc. Cytotoxic benzodiazepine derivatives
TWI697493B (zh) 2014-09-03 2020-07-01 美商免疫原公司 細胞毒性苯并二氮呯衍生物
TW201839001A (zh) 2017-04-20 2018-11-01 美商伊繆諾金公司 細胞毒性苯并二氮平衍生物及其綴合物
WO2019133652A1 (en) 2017-12-28 2019-07-04 Immunogen, Inc. Benzodiazepine derivatives
JP2022529583A (ja) 2019-03-29 2022-06-23 イミュノジェン・インコーポレーテッド 異常細胞増殖を阻害するまたは増殖性疾患を治療するための細胞毒性ビス－ベンゾジアゼピン誘導体及び細胞結合剤とのその複合体

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6156746A (en) * 1998-08-25 2000-12-05 Bristol-Myers Squibb Company 1,2,5-benzothiadiazepine-1,1-dioxides with n-2 imidazolylalkyl substituents

Also Published As

Publication number Publication date
US20080249080A1 (en) 2008-10-09
EP1910383B1 (de) 2009-09-16
WO2007015280A1 (en) 2007-02-08
DE602006009276D1 (de) 2009-10-29
ITRM20050416A1 (it) 2007-02-04
WO2007015280A8 (en) 2008-04-10
EP1910383A1 (de) 2008-04-16

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