ATE441643T1 - N-ä(4,5-diphenylpyrimidin-2- yl)methylüaminderivate, deren herstellung und deren therapeutische verwendung - Google Patents
N-ä(4,5-diphenylpyrimidin-2- yl)methylüaminderivate, deren herstellung und deren therapeutische verwendungInfo
- Publication number
- ATE441643T1 ATE441643T1 AT06778797T AT06778797T ATE441643T1 AT E441643 T1 ATE441643 T1 AT E441643T1 AT 06778797 T AT06778797 T AT 06778797T AT 06778797 T AT06778797 T AT 06778797T AT E441643 T1 ATE441643 T1 AT E441643T1
- Authority
- AT
- Austria
- Prior art keywords
- diphenylpyrimidine
- production
- therapeutic use
- amine derivatives
- methyl amine
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
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- A—HUMAN NECESSITIES
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- A61P1/12—Antidiarrhoeals
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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- A61P11/06—Antiasthmatics
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P15/06—Antiabortive agents; Labour repressants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/26—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Diabetes (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Hematology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Addiction (AREA)
- Psychiatry (AREA)
- Obesity (AREA)
- Endocrinology (AREA)
- Pulmonology (AREA)
- Urology & Nephrology (AREA)
- Oncology (AREA)
- Ophthalmology & Optometry (AREA)
- Hospice & Palliative Care (AREA)
- Reproductive Health (AREA)
- Communicable Diseases (AREA)
- Immunology (AREA)
- Pain & Pain Management (AREA)
- Gynecology & Obstetrics (AREA)
- Child & Adolescent Psychology (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0507359A FR2888237B1 (fr) | 2005-07-08 | 2005-07-08 | Derives de n-[(4,5-diphenylpyrimidin-2-yl)methyl] amine, leur preparation et leur application en therapeutique |
PCT/FR2006/001621 WO2007006928A1 (fr) | 2005-07-08 | 2006-07-06 | Derives de n-[(4,5-diphenylpyrimidin-2-yl)methyl] amine, leur preparation et leur application en therapeutique |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE441643T1 true ATE441643T1 (de) | 2009-09-15 |
Family
ID=35954079
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT06778797T ATE441643T1 (de) | 2005-07-08 | 2006-07-06 | N-ä(4,5-diphenylpyrimidin-2- yl)methylüaminderivate, deren herstellung und deren therapeutische verwendung |
Country Status (15)
Country | Link |
---|---|
US (1) | US7541361B2 (de) |
EP (1) | EP1937672B1 (de) |
JP (1) | JP2009500381A (de) |
AR (1) | AR054824A1 (de) |
AT (1) | ATE441643T1 (de) |
DE (1) | DE602006008971D1 (de) |
DO (1) | DOP2006000160A (de) |
FR (1) | FR2888237B1 (de) |
GT (1) | GT200600298A (de) |
JO (1) | JO2715B1 (de) |
PA (1) | PA8685401A1 (de) |
PE (1) | PE20070346A1 (de) |
TW (1) | TW200738691A (de) |
UY (1) | UY29658A1 (de) |
WO (1) | WO2007006928A1 (de) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BRPI0912539A2 (pt) * | 2008-05-05 | 2015-10-13 | Amgen Inc | composto, composição farmacêutica , método para tratar uma doença, e, uso do composto. |
GB201103419D0 (de) | 2011-02-28 | 2011-04-13 | Univ Aberdeen | |
TW201444798A (zh) | 2013-02-28 | 2014-12-01 | 必治妥美雅史谷比公司 | 作爲強效rock1及rock2抑制劑之苯基吡唑衍生物 |
JP6423372B2 (ja) | 2013-02-28 | 2018-11-14 | ブリストル−マイヤーズ スクイブ カンパニーBristol−Myers Squibb Company | 強力なrock1およびrock2阻害剤としてのフェニルピラゾール誘導体 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH06501926A (ja) * | 1990-08-06 | 1994-03-03 | 藤沢薬品工業株式会社 | 複素環式化合物 |
CA2499497A1 (en) * | 2002-09-27 | 2004-04-08 | Merck & Co., Inc. | Substituted pyrimidines |
US20040259887A1 (en) * | 2003-06-18 | 2004-12-23 | Pfizer Inc | Cannabinoid receptor ligands and uses thereof |
-
2005
- 2005-07-08 FR FR0507359A patent/FR2888237B1/fr not_active Expired - Fee Related
-
2006
- 2006-07-02 JO JOP/2006/0207A patent/JO2715B1/ar active
- 2006-07-04 DO DO2006000160A patent/DOP2006000160A/es unknown
- 2006-07-06 WO PCT/FR2006/001621 patent/WO2007006928A1/fr active Application Filing
- 2006-07-06 PE PE2006000806A patent/PE20070346A1/es not_active Application Discontinuation
- 2006-07-06 EP EP06778797A patent/EP1937672B1/de active Active
- 2006-07-06 JP JP2008519965A patent/JP2009500381A/ja active Pending
- 2006-07-06 PA PA20068685401A patent/PA8685401A1/es unknown
- 2006-07-06 GT GT200600298A patent/GT200600298A/es unknown
- 2006-07-06 DE DE602006008971T patent/DE602006008971D1/de active Active
- 2006-07-06 AT AT06778797T patent/ATE441643T1/de not_active IP Right Cessation
- 2006-07-07 UY UY29658A patent/UY29658A1/es unknown
- 2006-07-07 AR ARP060102939A patent/AR054824A1/es not_active Application Discontinuation
- 2006-07-07 TW TW095124916A patent/TW200738691A/zh unknown
-
2008
- 2008-01-03 US US11/968,855 patent/US7541361B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
JP2009500381A (ja) | 2009-01-08 |
PE20070346A1 (es) | 2007-05-04 |
WO2007006928A1 (fr) | 2007-01-18 |
UY29658A1 (es) | 2007-01-31 |
GT200600298A (es) | 2007-07-10 |
DOP2006000160A (es) | 2007-01-31 |
PA8685401A1 (es) | 2007-01-17 |
FR2888237A1 (fr) | 2007-01-12 |
TW200738691A (en) | 2007-10-16 |
US20080176867A1 (en) | 2008-07-24 |
AR054824A1 (es) | 2007-07-18 |
EP1937672A1 (de) | 2008-07-02 |
DE602006008971D1 (de) | 2009-10-15 |
JO2715B1 (ar) | 2014-03-15 |
FR2888237B1 (fr) | 2007-08-31 |
EP1937672B1 (de) | 2009-09-02 |
US7541361B2 (en) | 2009-06-02 |
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