ATE440108T1 - Plasmin-inhibitoren von der australischen braunen schlange, pseudonaja textilis textilis - Google Patents
Plasmin-inhibitoren von der australischen braunen schlange, pseudonaja textilis textilisInfo
- Publication number
- ATE440108T1 ATE440108T1 AT99918966T AT99918966T ATE440108T1 AT E440108 T1 ATE440108 T1 AT E440108T1 AT 99918966 T AT99918966 T AT 99918966T AT 99918966 T AT99918966 T AT 99918966T AT E440108 T1 ATE440108 T1 AT E440108T1
- Authority
- AT
- Austria
- Prior art keywords
- textilis
- inhibitors
- pseudonaja
- brown snake
- plasmin
- Prior art date
Links
- 241000427953 Pseudonaja textilis textilis Species 0.000 title abstract 2
- 241001074017 Storeria dekayi Species 0.000 title abstract 2
- 239000002806 plasmin inhibitor Substances 0.000 title abstract 2
- 239000003112 inhibitor Substances 0.000 abstract 2
- 102000040430 polynucleotide Human genes 0.000 abstract 2
- 108091033319 polynucleotide Proteins 0.000 abstract 2
- 239000002157 polynucleotide Substances 0.000 abstract 2
- 239000008280 blood Substances 0.000 abstract 1
- 210000004369 blood Anatomy 0.000 abstract 1
- 230000002860 competitive effect Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 229940012957 plasmin Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
- A61K47/6801—Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent
- A61K47/6803—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates
- A61K47/6811—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates the drug being a protein or peptide, e.g. transferrin or bleomycin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
- A61K47/6835—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site
- A61K47/6843—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting a material from animals or humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biochemistry (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AUPP3450A AUPP345098A0 (en) | 1998-05-11 | 1998-05-11 | Novel anti-fibrinolytic agents |
| PCT/AU1999/000343 WO1999058569A1 (en) | 1998-05-11 | 1999-05-07 | PLASMIN INHIBITORS FROM THE AUSTRALIAN BROWN SNAKE $i(PSEUDONAJA TEXTILIS TEXTILIS) |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE440108T1 true ATE440108T1 (de) | 2009-09-15 |
Family
ID=3807704
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99918966T ATE440108T1 (de) | 1998-05-11 | 1999-05-07 | Plasmin-inhibitoren von der australischen braunen schlange, pseudonaja textilis textilis |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US7070969B1 (enExample) |
| EP (1) | EP1078003B1 (enExample) |
| JP (1) | JP4542705B2 (enExample) |
| AT (1) | ATE440108T1 (enExample) |
| AU (1) | AUPP345098A0 (enExample) |
| CA (1) | CA2328431C (enExample) |
| DE (1) | DE69941292D1 (enExample) |
| DK (1) | DK1078003T3 (enExample) |
| ES (1) | ES2332249T3 (enExample) |
| NZ (1) | NZ508770A (enExample) |
| WO (1) | WO1999058569A1 (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AUPP345098A0 (en) * | 1998-05-11 | 1998-06-04 | National Institute Of Biological Standards And Control, United Kingdom | Novel anti-fibrinolytic agents |
| US6506365B1 (en) * | 2000-09-25 | 2003-01-14 | Baxter Aktiengesellschaft | Fibrin/fibrinogen binding conjugate |
| US7745192B2 (en) * | 2002-04-03 | 2010-06-29 | Venomics Pty Limited | Prothrombin activating protein |
| EP3088522B1 (en) | 2005-12-29 | 2017-11-29 | The Regents of the University of California | Methods and compositions related to mutant kunitz domain i of tfpi-2 |
| EP2154152A1 (en) * | 2008-08-08 | 2010-02-17 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Use of Conkunitzin-S1 for the modulation of glucose-induced insulin secretion |
| WO2010055950A1 (ja) * | 2008-11-17 | 2010-05-20 | 財団法人ヒューマンサイエンス振興財団 | 癌間質の構成因子に対して特異的結合能を有する物質と抗腫瘍性化合物との複合体による新規の癌ターゲティング治療 |
| CN102850451B (zh) * | 2011-06-29 | 2014-05-07 | 辽宁诺康生物制药有限责任公司 | 具有抑制纤溶酶活性的重组textilinin-1及其制备方法和应用 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5342830A (en) * | 1990-11-16 | 1994-08-30 | Cor Therapeutics, Inc. | Antithrombosis agents |
| EP0585504A1 (en) * | 1992-09-04 | 1994-03-09 | Pentapharm A.G. | Phospholipid dependant prothrombin activator and its use in lupus anticoagulant testing |
| AUPP076797A0 (en) * | 1997-12-05 | 1998-01-08 | Active (Pla) R&D Pty Ltd | Phospholipase inhibitor |
| AUPP345098A0 (en) * | 1998-05-11 | 1998-06-04 | National Institute Of Biological Standards And Control, United Kingdom | Novel anti-fibrinolytic agents |
-
1998
- 1998-05-11 AU AUPP3450A patent/AUPP345098A0/en not_active Abandoned
-
1999
- 1999-05-07 EP EP99918966A patent/EP1078003B1/en not_active Expired - Lifetime
- 1999-05-07 NZ NZ508770A patent/NZ508770A/en unknown
- 1999-05-07 JP JP2000548371A patent/JP4542705B2/ja not_active Expired - Fee Related
- 1999-05-07 WO PCT/AU1999/000343 patent/WO1999058569A1/en not_active Ceased
- 1999-05-07 AT AT99918966T patent/ATE440108T1/de not_active IP Right Cessation
- 1999-05-07 CA CA2328431A patent/CA2328431C/en not_active Expired - Fee Related
- 1999-05-07 DK DK99918966T patent/DK1078003T3/da active
- 1999-05-07 ES ES99918966T patent/ES2332249T3/es not_active Expired - Lifetime
- 1999-05-07 US US09/700,179 patent/US7070969B1/en not_active Expired - Lifetime
- 1999-05-07 DE DE69941292T patent/DE69941292D1/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| US7070969B1 (en) | 2006-07-04 |
| EP1078003B1 (en) | 2009-08-19 |
| DE69941292D1 (de) | 2009-10-01 |
| JP2002514404A (ja) | 2002-05-21 |
| CA2328431C (en) | 2010-04-27 |
| AUPP345098A0 (en) | 1998-06-04 |
| WO1999058569A1 (en) | 1999-11-18 |
| EP1078003A1 (en) | 2001-02-28 |
| NZ508770A (en) | 2003-12-19 |
| JP4542705B2 (ja) | 2010-09-15 |
| DK1078003T3 (da) | 2009-12-07 |
| ES2332249T3 (es) | 2010-01-29 |
| CA2328431A1 (en) | 1999-11-18 |
| EP1078003A4 (en) | 2004-08-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |