ATE433321T1 - Verwendung von amtolmetin guacyl für die behandlung von intestinalen entzündungen - Google Patents
Verwendung von amtolmetin guacyl für die behandlung von intestinalen entzündungenInfo
- Publication number
- ATE433321T1 ATE433321T1 AT99959678T AT99959678T ATE433321T1 AT E433321 T1 ATE433321 T1 AT E433321T1 AT 99959678 T AT99959678 T AT 99959678T AT 99959678 T AT99959678 T AT 99959678T AT E433321 T1 ATE433321 T1 AT E433321T1
- Authority
- AT
- Austria
- Prior art keywords
- treatment
- amtolmetin guacyl
- intestinal inflammation
- guacyl
- amtolmetin
- Prior art date
Links
- CWJNMKKMGIAGDK-UHFFFAOYSA-N amtolmetin guacil Chemical compound COC1=CC=CC=C1OC(=O)CNC(=O)CC(N1C)=CC=C1C(=O)C1=CC=C(C)C=C1 CWJNMKKMGIAGDK-UHFFFAOYSA-N 0.000 title abstract 3
- 229950003227 amtolmetin guacil Drugs 0.000 title abstract 3
- 206010061218 Inflammation Diseases 0.000 title 1
- 230000004054 inflammatory process Effects 0.000 title 1
- 230000000968 intestinal effect Effects 0.000 title 1
- 206010047141 Vasodilatation Diseases 0.000 abstract 1
- 230000000146 antalgic effect Effects 0.000 abstract 1
- 239000002260 anti-inflammatory agent Substances 0.000 abstract 1
- 229940124599 anti-inflammatory drug Drugs 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 229940127218 antiplatelet drug Drugs 0.000 abstract 1
- 210000001772 blood platelet Anatomy 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 208000010110 spontaneous platelet aggregation Diseases 0.000 abstract 1
- 201000005060 thrombophlebitis Diseases 0.000 abstract 1
- 230000001732 thrombotic effect Effects 0.000 abstract 1
- 230000024883 vasodilation Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Pyrrole Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT1998RM000745A IT1302898B1 (it) | 1998-12-03 | 1998-12-03 | Uso di amtolmetine guacil per la produzione di farmaci ad effettoantiinfiammatorio nelle infiammazioni intestinali. |
| PCT/IT1999/000398 WO2000032188A2 (en) | 1998-12-03 | 1999-12-03 | Use of amtolmetin guacyl as an antiinflammatory drug |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE433321T1 true ATE433321T1 (de) | 2009-06-15 |
Family
ID=11406239
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99959678T ATE433321T1 (de) | 1998-12-03 | 1999-12-03 | Verwendung von amtolmetin guacyl für die behandlung von intestinalen entzündungen |
| AT05111060T ATE433748T1 (de) | 1998-12-03 | 1999-12-03 | Verwendung von amtolmetin guacyl zur herstellung eines medikamentes zur verhinderung von blutplättchenaggregation |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT05111060T ATE433748T1 (de) | 1998-12-03 | 1999-12-03 | Verwendung von amtolmetin guacyl zur herstellung eines medikamentes zur verhinderung von blutplättchenaggregation |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US6495590B1 (de) |
| EP (2) | EP1135122B1 (de) |
| JP (1) | JP2003512293A (de) |
| KR (2) | KR100660487B1 (de) |
| AT (2) | ATE433321T1 (de) |
| AU (1) | AU1680100A (de) |
| BG (1) | BG65575B1 (de) |
| CA (2) | CA2634658A1 (de) |
| DE (2) | DE69941019D1 (de) |
| HU (1) | HUP0104491A3 (de) |
| IT (1) | IT1302898B1 (de) |
| PL (2) | PL201414B1 (de) |
| TR (1) | TR200101566T2 (de) |
| WO (1) | WO2000032188A2 (de) |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1210673B (it) * | 1982-02-26 | 1989-09-20 | Medosan Ind Biochimi | Antinfiammatoria amidi pirrolacetiche ad attivita' |
| IT1278144B1 (it) * | 1995-07-14 | 1997-11-17 | Medosan Ricerca Srl | Impiego dell'amtolmetineguacil (med 15) come farmaco antisecretivo sulla secrezione gastrica e quindi gastroprotettivo. |
| US5889041A (en) * | 1995-07-14 | 1999-03-30 | Medosan Ricerca S.R.L. | Method for treating an inflammatory pathological condition |
| US6180658B1 (en) * | 1995-07-14 | 2001-01-30 | Medosan Ricerca S.R.L. | Method for counteracting blood platelet aggregation in a patient in need thereof |
| ITMI962356A1 (it) * | 1996-11-13 | 1998-05-13 | Uni Degli Studi Di Brescia D I | Uso di composti derivati da molecole ad attivita' antinfiammatoria di tipo non steroideo per la prevenzione e il trattamento di |
| JP2001513497A (ja) * | 1997-08-08 | 2001-09-04 | メドサン、リセルカ エス．アール．エル． | 胃分泌過多および腎損傷の予防作用を有する抗炎症剤の製造のための化合物２−メトキシフェニル−１−メチル−５ｐ−メチルベンゾイル−ピロール−２−アセトアミドアセテートの使用 |
| EP1310250A1 (de) * | 1997-08-08 | 2003-05-14 | MEDOSAN RICERCA S.r.l. | Verwendung von 2-methoxyphenyl-1-methyl-5p-methyl-benzoylpyrrol-2-acetamido-acetat zur Herstellung eines Antientzündungsmittels mit Vorbeugung von Magenhypersekretion und Nierenfunktionsstörung |
-
1998
- 1998-12-03 IT IT1998RM000745A patent/IT1302898B1/it active IP Right Grant
-
1999
- 1999-12-03 JP JP2000584883A patent/JP2003512293A/ja active Pending
- 1999-12-03 WO PCT/IT1999/000398 patent/WO2000032188A2/en active IP Right Grant
- 1999-12-03 KR KR1020067014455A patent/KR100660487B1/ko not_active IP Right Cessation
- 1999-12-03 TR TR2001/01566T patent/TR200101566T2/xx unknown
- 1999-12-03 CA CA002634658A patent/CA2634658A1/en not_active Abandoned
- 1999-12-03 CA CA002353727A patent/CA2353727C/en not_active Expired - Fee Related
- 1999-12-03 PL PL381264A patent/PL201414B1/pl not_active IP Right Cessation
- 1999-12-03 US US09/857,432 patent/US6495590B1/en not_active Expired - Fee Related
- 1999-12-03 DE DE69941019T patent/DE69941019D1/de not_active Expired - Fee Related
- 1999-12-03 KR KR1020017006919A patent/KR100627750B1/ko not_active IP Right Cessation
- 1999-12-03 AT AT99959678T patent/ATE433321T1/de not_active IP Right Cessation
- 1999-12-03 DE DE69940979T patent/DE69940979D1/de not_active Expired - Fee Related
- 1999-12-03 AU AU16801/00A patent/AU1680100A/en not_active Abandoned
- 1999-12-03 EP EP99959678A patent/EP1135122B1/de not_active Expired - Lifetime
- 1999-12-03 EP EP05111060A patent/EP1709963B1/de not_active Expired - Lifetime
- 1999-12-03 HU HU0104491A patent/HUP0104491A3/hu unknown
- 1999-12-03 AT AT05111060T patent/ATE433748T1/de not_active IP Right Cessation
- 1999-12-03 PL PL99348645A patent/PL195790B1/pl not_active IP Right Cessation
-
2001
- 2001-05-31 BG BG105552A patent/BG65575B1/bg unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US6495590B1 (en) | 2002-12-17 |
| EP1135122B1 (de) | 2009-06-10 |
| BG65575B1 (bg) | 2009-01-30 |
| DE69941019D1 (de) | 2009-07-30 |
| KR100627750B1 (ko) | 2006-09-26 |
| DE69940979D1 (de) | 2009-07-23 |
| TR200101566T2 (tr) | 2001-10-22 |
| CA2353727C (en) | 2009-09-22 |
| CA2353727A1 (en) | 2000-06-08 |
| PL201414B1 (pl) | 2009-04-30 |
| WO2000032188A3 (en) | 2000-10-26 |
| EP1709963B1 (de) | 2009-06-17 |
| HUP0104491A3 (en) | 2002-12-28 |
| EP1135122A2 (de) | 2001-09-26 |
| KR20010108001A (ko) | 2001-12-07 |
| CA2634658A1 (en) | 2000-06-08 |
| WO2000032188A2 (en) | 2000-06-08 |
| IT1302898B1 (it) | 2000-10-10 |
| AU1680100A (en) | 2000-06-19 |
| ATE433748T1 (de) | 2009-07-15 |
| EP1709963A2 (de) | 2006-10-11 |
| KR20060089247A (ko) | 2006-08-08 |
| HUP0104491A2 (hu) | 2002-04-29 |
| ITRM980745A1 (it) | 2000-06-03 |
| JP2003512293A (ja) | 2003-04-02 |
| EP1709963A3 (de) | 2007-12-26 |
| KR100660487B1 (ko) | 2006-12-22 |
| PL195790B1 (pl) | 2007-10-31 |
| PL348645A1 (en) | 2002-06-03 |
| ITRM980745A0 (it) | 1998-12-03 |
| BG105552A (en) | 2001-12-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |