ATE427489T1 - Diagnostische marker fur ischamie und mortalitatsrisiken - Google Patents
Diagnostische marker fur ischamie und mortalitatsrisikenInfo
- Publication number
- ATE427489T1 ATE427489T1 AT02768861T AT02768861T ATE427489T1 AT E427489 T1 ATE427489 T1 AT E427489T1 AT 02768861 T AT02768861 T AT 02768861T AT 02768861 T AT02768861 T AT 02768861T AT E427489 T1 ATE427489 T1 AT E427489T1
- Authority
- AT
- Austria
- Prior art keywords
- ischemia
- diagnostic markers
- mortality risk
- concentration
- ischemic
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/92—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving lipids, e.g. cholesterol, lipoproteins, or their receptors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/28—Neurological disorders
- G01N2800/2871—Cerebrovascular disorders, e.g. stroke, cerebral infarct, cerebral haemorrhage, transient ischemic event
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/32—Cardiovascular disorders
- G01N2800/324—Coronary artery diseases, e.g. angina pectoris, myocardial infarction
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/805—Optical property
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/815—Test for named compound or class of compounds
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Veterinary Medicine (AREA)
- Biophysics (AREA)
- Endocrinology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Diabetes (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US32252301P | 2001-09-14 | 2001-09-14 | |
US10/243,566 US7262017B2 (en) | 2001-09-14 | 2002-09-13 | Diagnostic markers for ischemia |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE427489T1 true ATE427489T1 (de) | 2009-04-15 |
Family
ID=26935946
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT02768861T ATE427489T1 (de) | 2001-09-14 | 2002-09-16 | Diagnostische marker fur ischamie und mortalitatsrisiken |
Country Status (10)
Country | Link |
---|---|
US (2) | US7262017B2 (de) |
EP (1) | EP1425582B1 (de) |
JP (2) | JP4579537B2 (de) |
KR (1) | KR20040039177A (de) |
CN (1) | CN100554963C (de) |
AT (1) | ATE427489T1 (de) |
AU (1) | AU2002331867B2 (de) |
CA (1) | CA2425784A1 (de) |
DE (1) | DE60231814D1 (de) |
WO (1) | WO2003025571A1 (de) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20050154407A1 (en) * | 2000-12-20 | 2005-07-14 | Fox Hollow Technologies, Inc. | Method of evaluating drug efficacy for treating atherosclerosis |
US7699790B2 (en) * | 2000-12-20 | 2010-04-20 | Ev3, Inc. | Debulking catheters and methods |
US20100121360A9 (en) * | 2000-12-20 | 2010-05-13 | Fox Hollow Technologies, Inc | Testing a patient population having a cardiovascular condition for drug efficacy |
US7202089B2 (en) * | 2001-09-14 | 2007-04-10 | Alan Kleinfeld | Early diagnosis of stroke |
US7063782B2 (en) | 2001-11-26 | 2006-06-20 | Ischemia Technologies, Inc. | Electrochemical detection of ischemia |
US7074194B2 (en) | 2003-05-19 | 2006-07-11 | Ischemia Technologies, Inc. | Apparatus and method for risk stratification of patients with chest pain of suspected cardiac origin |
US7634360B2 (en) * | 2003-09-23 | 2009-12-15 | Prediction Sciences, LL | Cellular fibronectin as a diagnostic marker in stroke and methods of use thereof |
US7274772B2 (en) * | 2004-05-27 | 2007-09-25 | Cabot Microelectronics Corporation | X-ray source with nonparallel geometry |
WO2006036476A2 (en) * | 2004-09-07 | 2006-04-06 | The General Hospital Corporation | Methods of detecting myocardial ischemia and myocardial infarction |
US7794413B2 (en) * | 2005-04-19 | 2010-09-14 | Ev3, Inc. | Libraries and data structures of materials removed by debulking catheters |
US20080117416A1 (en) * | 2006-10-27 | 2008-05-22 | Hunter Ian W | Use of coherent raman techniques for medical diagnostic and therapeutic purposes, and calibration techniques for same |
WO2008060841A2 (en) * | 2006-10-27 | 2008-05-22 | Ffa Sciences, Llc | Use of probes for unbound metabolites |
US20100179066A1 (en) * | 2007-06-07 | 2010-07-15 | Inserm (Institut National De La Santé Et De La Rec | Method for Assessing the Risk of a Cardiovascular Disease and for Diagnosing Dyslipidemia |
WO2009036376A1 (en) * | 2007-09-13 | 2009-03-19 | University Of Hawaii | Fatty acid markers for the diagnosis, prognosis and management of cardiovascular disease |
JP5481023B2 (ja) * | 2007-10-25 | 2014-04-23 | 株式会社小松製作所 | 作業車両および作業車両の制御方法 |
WO2010077741A1 (en) * | 2008-12-09 | 2010-07-08 | The Trustees Of Columbia University In The City Of New York | Diagnosis and therapy of organ dysfunction using sphinganine-1-phosphate |
US20100228101A1 (en) * | 2009-03-04 | 2010-09-09 | Michael Maschke | Workflow for stroke diagnosis combining in-vitro diagnosis (ivd) with an imaging modality |
CN103154742B (zh) | 2010-06-20 | 2017-11-21 | 佐拉生物科学公司 | 用于鉴定高风险冠状动脉疾病患者的脂质组学标志 |
ES2595028T3 (es) | 2011-10-17 | 2016-12-27 | F. Hoffmann-La Roche Ag | Diagnóstico basado en Troponina y BNP de pacientes en riesgo y causa de ictus |
GB201304460D0 (en) | 2013-03-13 | 2013-04-24 | Univ Leeds | Biomarker |
EP3077827B1 (de) | 2013-12-03 | 2023-11-01 | Kleinfeld, Alan M. | Bestimmung der ungebundenen freien fettsäureprofile in biologischen und industriellen proben |
GB201509974D0 (en) * | 2015-06-09 | 2015-07-22 | Sarissa Biomedical Ltd | Methods and device to detect the presence of ischaemia in a subject |
Family Cites Families (42)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5217085A (en) | 1975-07-30 | 1977-02-08 | Ono Pharmaceut Co Ltd | Method of quantitative determination of free fatty acids in serum usin g fatty acid activating enzymes |
FR2508487B1 (fr) | 1981-06-25 | 1986-06-27 | Toyo Jozo Kk | Procede de dosage pour composant apparente aux lipides, composition pour dosage et procede de production d'enzyme utilisee a cet effet |
US4369250A (en) | 1981-07-31 | 1983-01-18 | Sherwood Medical Industries Inc. | Fatty acid determination |
SU1270706A1 (ru) | 1981-09-30 | 1986-11-15 | Украинский научно-исследовательский институт кардиологии им.акад.Н.Д.Стражеско | Способ определени фосфолипидов в инфарктной зоне сердечной мышцы |
AT390840B (de) | 1983-06-08 | 1990-07-10 | Avl Verbrennungskraft Messtech | Verfahren zur fluorimetrischen bestimmung der konzentration von in einer substanz enthaltenen stoffen und anordnung zur durchfuehrung dieses verfahrens |
JP2657225B2 (ja) * | 1987-03-31 | 1997-09-24 | 株式会社 日本抗体研究所 | 脂質代謝異常の検出方法 |
US4833332A (en) | 1987-06-12 | 1989-05-23 | E. I. Du Pont De Nemours And Company | Scanning fluorescent detection system |
US5512429A (en) | 1989-09-19 | 1996-04-30 | British Technology Group Limited | Assay for enzyme activity |
DE69023488T2 (de) | 1989-12-12 | 1996-05-09 | Lidak Pharmaceuticals | BESTIMMUNG FREIER FETTSäUREN. |
US5470714A (en) | 1989-12-12 | 1995-11-28 | Lidak Pharmaceuticals | One-step free fatty acid determination method |
US5604105B1 (en) | 1990-10-12 | 1999-08-24 | Spectral Diagnostics Inc | Method and device for diagnosingand distinguishing chest pain in early onset thereof |
GB9105707D0 (en) | 1991-03-18 | 1991-05-01 | Wilton David C | Assay |
US5227307A (en) * | 1991-07-26 | 1993-07-13 | Diagnostic Markers, Inc. | Test for the rapid evaluation of ischemic state |
US5225329A (en) | 1991-10-18 | 1993-07-06 | Yale University | Method for early detection of intestinal ischemia |
WO1994006014A1 (en) | 1992-09-02 | 1994-03-17 | Kleinfeld Alan M | Diagnostic aid for early detection of cancer and diabetes |
US5362649A (en) | 1993-02-16 | 1994-11-08 | The United States Of America As Represented By The Secretary Of The Air Force | Method for concentration based analysis of lipid fatty acids and its use in determining the likelihood that a patient is at risk for coronary artery disease |
US5914112A (en) | 1996-01-23 | 1999-06-22 | Genentech, Inc. | Anti-CD18 antibodies in stroke |
WO1998057179A1 (en) * | 1997-06-10 | 1998-12-17 | Medlyte Diagnostics, Inc. | Methods for early detection of heart disease |
AU3395697A (en) | 1997-06-13 | 1998-12-30 | Medical Biology Institute | Method of detection of cardiac ischemia using fatty acid binding protein |
US6444432B1 (en) | 1997-06-13 | 2002-09-03 | Alan M. Kleinfeld | Method of detection of cardiac ischemia using fatty acid binding protein |
US6727258B2 (en) | 1997-10-29 | 2004-04-27 | King Pharmaceutical Research & Development, Inc. | Allosteric adenosine receptor modulators |
TW562926B (en) | 1997-11-26 | 2003-11-21 | Tanabe Seiyaku Co | Method for testing renal diseases |
US5977174A (en) | 1997-11-26 | 1999-11-02 | Neuromedica, Inc. | Cholinergic compositions and uses thereof |
DE19836617C2 (de) * | 1998-08-12 | 2001-02-08 | Ulrich Frei | In vitro Verfahren zur Erkennung und Diagnostik akuter koronarer Syndrome |
US6461875B1 (en) * | 1998-10-02 | 2002-10-08 | Ischemia Technologies, Inc. | Test for rapid evaluation of ischemic states and kit |
US6475743B1 (en) * | 1998-10-02 | 2002-11-05 | Ischemia Technologies, Inc. | Marker useful for detection and measurement of free radical damage and method |
US6492179B1 (en) * | 1998-10-02 | 2002-12-10 | Ischemia Techologies, Inc. | Test for rapid evaluation of ischemic states and kit |
WO2000020840A1 (en) | 1998-10-02 | 2000-04-13 | Ischemia Technologies, Inc. | Tests for the rapid evaluation of ischemic states and kits |
US6264960B1 (en) | 1998-11-10 | 2001-07-24 | Sander J. Robins | Treatment of vascular events using lipid-modifying compositions |
JP2002536459A (ja) | 1999-02-12 | 2002-10-29 | プレジデント アンド フェローズ オブ ハーヴァード カレッジ | アテローム性動脈硬化症性病変の形成の阻害 |
US6663862B1 (en) | 1999-06-04 | 2003-12-16 | Duke University | Reagents for detection and purification of antibody fragments |
GB9923146D0 (en) | 1999-09-30 | 1999-12-01 | Imperial College | Detector array |
US6563585B1 (en) | 1999-11-24 | 2003-05-13 | University Of Maryland Biotechnology Institute | Ratiometric fluorometer |
US20040077017A1 (en) | 2001-01-12 | 2004-04-22 | Amelie Karlstrom | Detection methods |
WO2002072872A2 (en) | 2001-03-14 | 2002-09-19 | Clf Medical Technology Acceleration Program, Inc. | System for screening fatty acid transport inhibitors, methods of use and modulators identified thereby |
WO2002089656A2 (en) | 2001-05-04 | 2002-11-14 | Ischemia Technologies, Inc. | Diagnosis of acute myocardial infarction |
US7202089B2 (en) | 2001-09-14 | 2007-04-10 | Alan Kleinfeld | Early diagnosis of stroke |
US20050239155A1 (en) | 2002-01-04 | 2005-10-27 | Javier Alarcon | Entrapped binding protein as biosensors |
AU2003228817A1 (en) | 2002-05-01 | 2003-11-17 | Adipogenix, Inc. | Human adipocyte cell populations and methods for identifying modulators of same |
US7335481B2 (en) | 2002-07-24 | 2008-02-26 | Christer Owman | Methods of identifying compounds that affect a fatty acid cell-surface receptor |
AU2005227312B2 (en) | 2004-03-22 | 2011-04-07 | Ffa Sciences, Llp | Development and use of fluorescent probes of unbound analytes |
US20060257938A1 (en) | 2005-05-10 | 2006-11-16 | Kleinfeld Alan M | Method of screening for drugs that block ligand binding to a lipid binding protein |
-
2002
- 2002-09-13 US US10/243,566 patent/US7262017B2/en active Active
- 2002-09-16 WO PCT/US2002/029477 patent/WO2003025571A1/en active IP Right Grant
- 2002-09-16 JP JP2003529149A patent/JP4579537B2/ja not_active Expired - Fee Related
- 2002-09-16 EP EP02768861A patent/EP1425582B1/de not_active Expired - Lifetime
- 2002-09-16 AT AT02768861T patent/ATE427489T1/de not_active IP Right Cessation
- 2002-09-16 AU AU2002331867A patent/AU2002331867B2/en not_active Ceased
- 2002-09-16 CN CNB02802866XA patent/CN100554963C/zh not_active Expired - Fee Related
- 2002-09-16 KR KR10-2003-7006578A patent/KR20040039177A/ko active Search and Examination
- 2002-09-16 CA CA002425784A patent/CA2425784A1/en not_active Abandoned
- 2002-09-16 DE DE60231814T patent/DE60231814D1/de not_active Expired - Lifetime
-
2007
- 2007-08-20 US US11/841,480 patent/US7879558B2/en not_active Expired - Lifetime
-
2010
- 2010-06-30 JP JP2010149527A patent/JP5244156B2/ja not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
CN1630818A (zh) | 2005-06-22 |
WO2003025571A1 (en) | 2003-03-27 |
JP2010223972A (ja) | 2010-10-07 |
CA2425784A1 (en) | 2003-03-27 |
US7262017B2 (en) | 2007-08-28 |
JP5244156B2 (ja) | 2013-07-24 |
EP1425582A4 (de) | 2005-02-16 |
US20030064522A1 (en) | 2003-04-03 |
US7879558B2 (en) | 2011-02-01 |
US20080004210A1 (en) | 2008-01-03 |
EP1425582B1 (de) | 2009-04-01 |
EP1425582A1 (de) | 2004-06-09 |
JP4579537B2 (ja) | 2010-11-10 |
KR20040039177A (ko) | 2004-05-10 |
DE60231814D1 (de) | 2009-05-14 |
JP2005504277A (ja) | 2005-02-10 |
AU2002331867B2 (en) | 2007-08-02 |
CN100554963C (zh) | 2009-10-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |