ATE424394T1 - 1h-indol-3-carbonsäurederivate und deren verwendung als ppar-agonisten - Google Patents
1h-indol-3-carbonsäurederivate und deren verwendung als ppar-agonistenInfo
- Publication number
- ATE424394T1 ATE424394T1 AT05817577T AT05817577T ATE424394T1 AT E424394 T1 ATE424394 T1 AT E424394T1 AT 05817577 T AT05817577 T AT 05817577T AT 05817577 T AT05817577 T AT 05817577T AT E424394 T1 ATE424394 T1 AT E424394T1
- Authority
- AT
- Austria
- Prior art keywords
- indole
- acid derivatives
- carbonic acid
- ppar agonists
- compounds
- Prior art date
Links
- 102000003728 Peroxisome Proliferator-Activated Receptors Human genes 0.000 title 1
- 108090000029 Peroxisome Proliferator-Activated Receptors Proteins 0.000 title 1
- 239000000556 agonist Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- 201000001320 Atherosclerosis Diseases 0.000 abstract 1
- 208000032928 Dyslipidaemia Diseases 0.000 abstract 1
- 206010012601 diabetes mellitus Diseases 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Diabetes (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Cardiology (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0500422A FR2880889B1 (fr) | 2005-01-14 | 2005-01-14 | Derives de l'acide 1h-indole-3-carboxylique, procedes pour leur preparation, compositions pharmaceutiques les contenant et applications en therapeutique |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE424394T1 true ATE424394T1 (de) | 2009-03-15 |
Family
ID=34953245
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT05817577T ATE424394T1 (de) | 2005-01-14 | 2005-12-17 | 1h-indol-3-carbonsäurederivate und deren verwendung als ppar-agonisten |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US7754740B2 (de) |
| EP (1) | EP1836187B1 (de) |
| JP (1) | JP5042855B2 (de) |
| KR (1) | KR20070104353A (de) |
| CN (1) | CN101098865A (de) |
| AT (1) | ATE424394T1 (de) |
| AU (1) | AU2005324895B2 (de) |
| BR (1) | BRPI0519839A2 (de) |
| CA (1) | CA2594377C (de) |
| DE (1) | DE602005013118D1 (de) |
| ES (1) | ES2321745T3 (de) |
| FR (1) | FR2880889B1 (de) |
| MX (1) | MX2007008350A (de) |
| WO (1) | WO2006074789A1 (de) |
| ZA (1) | ZA200706707B (de) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7994331B2 (en) | 2005-07-13 | 2011-08-09 | Msd K.K. | Heterocycle-substituted benzimidazole derivative |
| CN103880730A (zh) * | 2014-02-26 | 2014-06-25 | 南通大学 | 一种7-硝基吲哚-3-甲酸叔丁酯的化学合成方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2427499A1 (en) * | 2000-10-10 | 2002-04-18 | Smithkline Beecham Corporation | Substituted indoles, pharmaceutical compositions containing such indoles and their use as ppar-.gamma. binding agents |
| WO2002046154A1 (fr) * | 2000-12-05 | 2002-06-13 | Nippon Chemiphar Co., Ltd. | Activateurs $g(d) de recepteur active par un proliferateur du peroxysome |
| WO2005042497A2 (en) * | 2003-10-28 | 2005-05-12 | Vertex Pharmaceuticals, Incorporated | Benzimidazoles useful as modulators of ion channels |
-
2005
- 2005-01-14 FR FR0500422A patent/FR2880889B1/fr not_active Expired - Fee Related
- 2005-12-17 AT AT05817577T patent/ATE424394T1/de not_active IP Right Cessation
- 2005-12-17 MX MX2007008350A patent/MX2007008350A/es not_active Application Discontinuation
- 2005-12-17 JP JP2007550701A patent/JP5042855B2/ja not_active Expired - Fee Related
- 2005-12-17 BR BRPI0519839-9A patent/BRPI0519839A2/pt not_active Application Discontinuation
- 2005-12-17 US US11/813,922 patent/US7754740B2/en not_active Expired - Fee Related
- 2005-12-17 AU AU2005324895A patent/AU2005324895B2/en not_active Ceased
- 2005-12-17 DE DE602005013118T patent/DE602005013118D1/de not_active Expired - Lifetime
- 2005-12-17 EP EP05817577A patent/EP1836187B1/de not_active Expired - Lifetime
- 2005-12-17 CA CA2594377A patent/CA2594377C/en not_active Expired - Fee Related
- 2005-12-17 ES ES05817577T patent/ES2321745T3/es not_active Expired - Lifetime
- 2005-12-17 KR KR1020077016037A patent/KR20070104353A/ko not_active Withdrawn
- 2005-12-17 CN CNA2005800465385A patent/CN101098865A/zh active Pending
- 2005-12-17 WO PCT/EP2005/013634 patent/WO2006074789A1/en not_active Ceased
-
2007
- 2007-08-13 ZA ZA200706707A patent/ZA200706707B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE602005013118D1 (de) | 2009-04-16 |
| EP1836187A1 (de) | 2007-09-26 |
| BRPI0519839A2 (pt) | 2009-03-17 |
| JP2008526902A (ja) | 2008-07-24 |
| US20080114034A1 (en) | 2008-05-15 |
| ZA200706707B (en) | 2008-09-25 |
| FR2880889A1 (fr) | 2006-07-21 |
| CA2594377A1 (en) | 2006-07-20 |
| JP5042855B2 (ja) | 2012-10-03 |
| CN101098865A (zh) | 2008-01-02 |
| AU2005324895A1 (en) | 2006-07-20 |
| WO2006074789A1 (en) | 2006-07-20 |
| MX2007008350A (es) | 2007-07-25 |
| CA2594377C (en) | 2014-02-18 |
| FR2880889B1 (fr) | 2007-04-06 |
| US7754740B2 (en) | 2010-07-13 |
| AU2005324895B2 (en) | 2011-08-04 |
| EP1836187B1 (de) | 2009-03-04 |
| ES2321745T3 (es) | 2009-06-10 |
| KR20070104353A (ko) | 2007-10-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |