ATE424224T1 - Dezellularisierung von gewebematrixen - Google Patents
Dezellularisierung von gewebematrixenInfo
- Publication number
- ATE424224T1 ATE424224T1 AT02735577T AT02735577T ATE424224T1 AT E424224 T1 ATE424224 T1 AT E424224T1 AT 02735577 T AT02735577 T AT 02735577T AT 02735577 T AT02735577 T AT 02735577T AT E424224 T1 ATE424224 T1 AT E424224T1
- Authority
- AT
- Austria
- Prior art keywords
- decellularization
- tissue
- implantation
- matrices
- matrixes
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
- A61L27/3687—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment characterised by the use of chemical agents in the treatment, e.g. specific enzymes, detergents, capping agents, crosslinkers, anticalcification agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
- A61L27/3633—Extracellular matrix [ECM]
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Botany (AREA)
- Dermatology (AREA)
- Medicinal Chemistry (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- General Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Biophysics (AREA)
- Enzymes And Modification Thereof (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Detergent Compositions (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Materials For Medical Uses (AREA)
- Apparatus For Radiation Diagnosis (AREA)
- Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)
- Inorganic Insulating Materials (AREA)
- Magnetic Ceramics (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB0112586A GB2375771A (en) | 2001-05-24 | 2001-05-24 | Decellularisation of tissue implant material |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE424224T1 true ATE424224T1 (de) | 2009-03-15 |
Family
ID=9915172
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT02735577T ATE424224T1 (de) | 2001-05-24 | 2002-05-20 | Dezellularisierung von gewebematrixen |
Country Status (9)
Country | Link |
---|---|
US (1) | US7354749B2 (de) |
EP (1) | EP1392372B1 (de) |
AT (1) | ATE424224T1 (de) |
AU (1) | AU2002310589B2 (de) |
CA (1) | CA2447847C (de) |
DE (1) | DE60231395D1 (de) |
ES (1) | ES2322891T3 (de) |
GB (1) | GB2375771A (de) |
WO (1) | WO2002096476A1 (de) |
Families Citing this family (46)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6214054B1 (en) * | 1998-09-21 | 2001-04-10 | Edwards Lifesciences Corporation | Method for fixation of biological tissues having mitigated propensity for post-implantation calcification and thrombosis and bioprosthetic devices prepared thereby |
US6878168B2 (en) | 2002-01-03 | 2005-04-12 | Edwards Lifesciences Corporation | Treatment of bioprosthetic tissues to mitigate post implantation calcification |
US20050013870A1 (en) * | 2003-07-17 | 2005-01-20 | Toby Freyman | Decellularized extracellular matrix of conditioned body tissues and uses thereof |
DE102004047247B3 (de) * | 2004-09-22 | 2006-03-16 | Auto Tissue Gmbh | Sterilisationsverfahren zur Herstellung von implantierbarem oder transplantierbarem biologischem Material |
CA2618731C (en) | 2005-08-26 | 2021-12-28 | Regents Of The University Of Minnesota | Decellularization and recellularization of organs and tissues |
US20100093066A1 (en) * | 2005-08-26 | 2010-04-15 | Regents Of The University Of Minnesota | Decellularization and recellularization apparatuses and systems containing the same |
GB0606231D0 (en) * | 2006-03-29 | 2006-05-10 | Univ Leeds | Improvements relating to decellurisation of tissue matrices for bladder implantation |
CN103933612B (zh) | 2006-10-27 | 2016-06-22 | 爱德华兹生命科学公司 | 用于外科植入的生物组织 |
EP2094325B1 (de) * | 2006-11-16 | 2011-08-31 | The University Of Leeds | Vorbereitung von gewebe für die meniskus-implantation |
US9101691B2 (en) * | 2007-06-11 | 2015-08-11 | Edwards Lifesciences Corporation | Methods for pre-stressing and capping bioprosthetic tissue |
JP2009050297A (ja) * | 2007-08-23 | 2009-03-12 | Tokyo Medical & Dental Univ | 脱細胞処理液、脱細胞化組織の調製方法、移植片、及び培養部材 |
US8357387B2 (en) * | 2007-12-21 | 2013-01-22 | Edwards Lifesciences Corporation | Capping bioprosthetic tissue to reduce calcification |
FR2951549B1 (fr) | 2009-10-15 | 2013-08-23 | Olivier Schussler | Procede d'obtention de bioprotheses medicales implantables |
US20110165676A1 (en) * | 2009-11-06 | 2011-07-07 | The Children's Mercy Hospital | Method for decellularization |
EP3545980A1 (de) | 2010-02-26 | 2019-10-02 | DeCell Technologies Inc. | Verfahren zur gewebeentzellularisierung |
CA2794121C (en) | 2010-03-23 | 2016-10-11 | Edwards Lifesciences Corporation | Methods of conditioning sheet bioprosthetic tissue |
WO2011160085A2 (en) * | 2010-06-17 | 2011-12-22 | Edwards Lifesciences Corporation | Methods for stabilizing a bioprosthetic tissue by chemical modification of antigenic carbohydrates |
US8906601B2 (en) * | 2010-06-17 | 2014-12-09 | Edwardss Lifesciences Corporation | Methods for stabilizing a bioprosthetic tissue by chemical modification of antigenic carbohydrates |
US8435305B2 (en) | 2010-08-31 | 2013-05-07 | Zimmer, Inc. | Osteochondral graft delivery device and uses thereof |
RU2611361C2 (ru) | 2010-09-01 | 2017-02-21 | Риджентс Оф Дзе Юниверсити Оф Миннесота | Способы рецеллюляризации ткани или органа для улучшения приживления трансплантата |
AU2011309900B2 (en) * | 2010-09-27 | 2014-07-24 | Tissue Regenix Limited | Acellular vascular products |
US9351829B2 (en) | 2010-11-17 | 2016-05-31 | Edwards Lifesciences Corporation | Double cross-linkage process to enhance post-implantation bioprosthetic tissue durability |
US9290738B2 (en) | 2012-06-13 | 2016-03-22 | Miromatrix Medical Inc. | Methods of decellularizing bone |
RU2499611C1 (ru) * | 2012-09-28 | 2013-11-27 | Федеральное государственное бюджетное учреждение науки Институт теоретической и экспериментальной биофизики Российской академии наук (ИТЭБ РАН) | Способ повышения биосовместимости трансплантатов клапанов сердца и сосудов |
US10238771B2 (en) | 2012-11-08 | 2019-03-26 | Edwards Lifesciences Corporation | Methods for treating bioprosthetic tissue using a nucleophile/electrophile in a catalytic system |
ES2831756T3 (es) | 2013-03-15 | 2021-06-09 | Miromatrix Medical Inc | Uso de hígado descelularizado por perfusión para la recelularización de células de islotes |
EP3027235A1 (de) | 2013-07-30 | 2016-06-08 | Musculoskeletal Transplant Foundation | Aus einem azellulären weichgewebe gewonnene matrizen und verfahren zur herstellung davon |
US9615922B2 (en) | 2013-09-30 | 2017-04-11 | Edwards Lifesciences Corporation | Method and apparatus for preparing a contoured biological tissue |
US10959839B2 (en) | 2013-10-08 | 2021-03-30 | Edwards Lifesciences Corporation | Method for directing cellular migration patterns on a biological tissue |
AU2014341866B2 (en) | 2013-11-04 | 2018-07-05 | Lifecell Corporation | Methods of removing alpha-galactose |
RU2586952C1 (ru) * | 2015-07-20 | 2016-06-10 | Федеральное государственное бюджетное учреждение "Федеральный научный центр трансплантологии и искусственных органов имени академика В.И. Шумакова" Министерства здравоохранения Российской Федерации | Способ лечения печеночной недостаточности |
US10912864B2 (en) | 2015-07-24 | 2021-02-09 | Musculoskeletal Transplant Foundation | Acellular soft tissue-derived matrices and methods for preparing same |
US11052175B2 (en) | 2015-08-19 | 2021-07-06 | Musculoskeletal Transplant Foundation | Cartilage-derived implants and methods of making and using same |
CN105709276B (zh) * | 2016-01-28 | 2018-08-10 | 成都清科生物科技有限公司 | 一种绒毛膜脱细胞液以及脱细胞方法 |
US11278643B2 (en) | 2016-09-06 | 2022-03-22 | Mayo Foundation For Medical Education And Research | Use of resected liver serum for whole liver-engineering |
WO2018222434A1 (en) | 2017-05-31 | 2018-12-06 | Edwards Lifesciences Corporation | Collagen fibers and articles formed therefrom |
CN107596446B (zh) * | 2017-09-16 | 2020-07-28 | 温州医科大学 | 一种维持组织超微结构和营养微环境的脱细胞试剂盒 |
SG11202003938PA (en) | 2018-01-23 | 2020-08-28 | Edwards Lifesciences Corp | Method for pre-stretching implantable biocompatible materials, and materials and devices produced thereby |
RU2678966C1 (ru) * | 2018-04-03 | 2019-02-05 | ООО "БиоИн-М" | Способ повышения биосовместимости перикардиальных биоматериалов для реконструктивной хирургии |
CN109260517B (zh) * | 2018-09-19 | 2020-10-30 | 杭州启明医疗器械股份有限公司 | 一种可预装干燥生物心脏瓣膜及其制备方法 |
EP3852683B1 (de) | 2018-11-01 | 2024-05-29 | Edwards Lifesciences Corporation | Pulmonales regeneratives transkatheterventil |
GB202003210D0 (en) | 2020-03-05 | 2020-04-22 | Tissue Regenix Ltd | A method for producing a decellularized tissue scaffold |
US11998662B1 (en) | 2021-06-09 | 2024-06-04 | Reprise Biomedical, Inc. | Biologic matrix for a wound site and related methods |
CN113368313B (zh) * | 2021-06-10 | 2022-06-03 | 吾奇生物医疗科技(江苏)有限公司 | 一种生物膜的制备方法及其产品和应用 |
CN115006594B (zh) * | 2022-06-26 | 2023-07-11 | 中国海洋大学 | 机械增强型脱细胞猪角膜后板层载体支架制备方法及应用 |
CN115453021B (zh) * | 2022-08-15 | 2023-11-14 | 首都医科大学附属北京友谊医院 | 一种sds脱细胞溶液及其在脱细胞处理或细胞外基质不可溶组分鉴定中的应用 |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IN157379B (de) * | 1981-04-30 | 1986-03-15 | Extracorporeal Med Spec | |
US4323358A (en) * | 1981-04-30 | 1982-04-06 | Vascor, Inc. | Method for inhibiting mineralization of natural tissue during implantation |
US6100064A (en) * | 1984-04-06 | 2000-08-08 | Chiron Corporation | Secreted viral proteins useful for vaccines and diagnostics |
GB8618374D0 (en) * | 1986-07-28 | 1986-09-03 | Hsc Res Dev Corp | Biological vascular prostheses |
US5336616A (en) * | 1990-09-12 | 1994-08-09 | Lifecell Corporation | Method for processing and preserving collagen-based tissues for transplantation |
AU1931495A (en) * | 1994-03-14 | 1995-10-03 | Cryolife, Inc. | Treated tissue for implantation and preparation methods |
EP0804127A1 (de) * | 1994-07-28 | 1997-11-05 | Ivan Vesely | Bioprosthetische implantate sowie herstellungs- und gebrauchsverfahren |
US5986054A (en) * | 1995-04-28 | 1999-11-16 | The Hospital For Sick Children, Hsc Research And Development Limited Partnership | Genetic sequences and proteins related to alzheimer's disease |
US6147080A (en) * | 1996-12-18 | 2000-11-14 | Vertex Pharmaceuticals Incorporated | Inhibitors of p38 |
JP2002503678A (ja) * | 1998-02-20 | 2002-02-05 | ライフセル コーポレーション | コラーゲンベース組織の処理および保存方法 |
US6962814B2 (en) * | 2000-08-16 | 2005-11-08 | Duke University | Decellularized tissue engineered constructs and tissues |
-
2001
- 2001-05-24 GB GB0112586A patent/GB2375771A/en not_active Withdrawn
-
2002
- 2002-05-20 CA CA2447847A patent/CA2447847C/en not_active Expired - Lifetime
- 2002-05-20 ES ES02735577T patent/ES2322891T3/es not_active Expired - Lifetime
- 2002-05-20 AU AU2002310589A patent/AU2002310589B2/en not_active Expired
- 2002-05-20 AT AT02735577T patent/ATE424224T1/de not_active IP Right Cessation
- 2002-05-20 US US10/478,198 patent/US7354749B2/en not_active Expired - Lifetime
- 2002-05-20 EP EP02735577A patent/EP1392372B1/de not_active Expired - Lifetime
- 2002-05-20 WO PCT/GB2002/002341 patent/WO2002096476A1/en not_active Application Discontinuation
- 2002-05-20 DE DE60231395T patent/DE60231395D1/de not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
EP1392372A1 (de) | 2004-03-03 |
ES2322891T3 (es) | 2009-07-01 |
US7354749B2 (en) | 2008-04-08 |
GB0112586D0 (en) | 2001-07-18 |
AU2002310589B2 (en) | 2007-01-25 |
EP1392372B1 (de) | 2009-03-04 |
WO2002096476A1 (en) | 2002-12-05 |
US20040157206A1 (en) | 2004-08-12 |
CA2447847A1 (en) | 2002-12-05 |
DE60231395D1 (de) | 2009-04-16 |
CA2447847C (en) | 2011-11-22 |
GB2375771A (en) | 2002-11-27 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |