ATE42304T1 - 4-amino-3-halo-2-pyridinone nukleosid- und nukleotid-verbindungen. - Google Patents

4-amino-3-halo-2-pyridinone nukleosid- und nukleotid-verbindungen.

Info

Publication number
ATE42304T1
ATE42304T1 AT86110427T AT86110427T ATE42304T1 AT E42304 T1 ATE42304 T1 AT E42304T1 AT 86110427 T AT86110427 T AT 86110427T AT 86110427 T AT86110427 T AT 86110427T AT E42304 T1 ATE42304 T1 AT E42304T1
Authority
AT
Austria
Prior art keywords
pyridinone
nucleoside
halo
amino
nucleotide compounds
Prior art date
Application number
AT86110427T
Other languages
English (en)
Inventor
Dennis J Mcnamara
Phillip Dan Cook
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Application granted granted Critical
Publication of ATE42304T1 publication Critical patent/ATE42304T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/048—Pyridine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Hematology (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT86110427T 1985-07-29 1986-07-29 4-amino-3-halo-2-pyridinone nukleosid- und nukleotid-verbindungen. ATE42304T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/759,816 US4681873A (en) 1985-07-29 1985-07-29 4-amino-3-halo-2-pyridinone nucleoside and nucleotide compounds
EP86110427A EP0210639B1 (de) 1985-07-29 1986-07-29 4-Amino-3-halo-2-pyridinone Nukleosid- und Nukleotid-Verbindungen

Publications (1)

Publication Number Publication Date
ATE42304T1 true ATE42304T1 (de) 1989-05-15

Family

ID=25057063

Family Applications (1)

Application Number Title Priority Date Filing Date
AT86110427T ATE42304T1 (de) 1985-07-29 1986-07-29 4-amino-3-halo-2-pyridinone nukleosid- und nukleotid-verbindungen.

Country Status (5)

Country Link
US (1) US4681873A (de)
EP (1) EP0210639B1 (de)
JP (1) JPS6270387A (de)
AT (1) ATE42304T1 (de)
DE (1) DE3662895D1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5644043A (en) * 1988-02-16 1997-07-01 Eli Lilly And Company 2',3'-dideoxy-2',2'-difluoronucleosides and intermediates
EP0389723A1 (de) * 1989-03-29 1990-10-03 Merrell Dow Pharmaceuticals Inc. Alpha-glukosidase-Inhibitoren
US5134066A (en) * 1989-08-29 1992-07-28 Monsanto Company Improved probes using nucleosides containing 3-dezauracil analogs

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2802005A (en) * 1957-08-06 S-eluorourace
US2885396A (en) * 1957-03-21 1959-05-05 Heidelberger Charles N-glycosides of 5-fluorouracil
US3355278A (en) * 1961-03-13 1967-11-28 Hooker Chemical Corp Herbicidal composition and method
US3201389A (en) * 1962-09-24 1965-08-17 Kyowa Hakko Kogyo Kk Method for preparing ribonucleoside-5'-phosphates or their salts from ribonucleosides
GB1100825A (en) * 1964-05-11 1968-01-24 Robert Neville Haszeldine Polyfluoropyridine compounds
NL6816241A (de) * 1967-12-01 1969-06-03
US3705147A (en) * 1969-08-22 1972-12-05 Univ Utah 3-deazapyrimidine nucleosides and method of preparation thereof
BE758759A (fr) * 1969-11-12 1971-05-10 Merck & Co Inc Pyridones anti-inflammatoires
US3721676A (en) * 1969-11-12 1973-03-20 Merck & Co Inc Certain 3-amino-2(1h)pyridones
US3853897A (en) * 1971-07-16 1974-12-10 Merck & Co Inc Certain 1-substituted-3-amino-1(2h)pyridones
US3836645A (en) * 1972-06-23 1974-09-17 Icn Pharmaceuticals Anti-viral compositions containing 3-deaza nucleosides
EP0015584A3 (de) * 1979-03-12 1980-12-10 Kailash Kumar Dr. Prof. Gauri Neue Nukleotide, Verfahren zu ihrer Herstellung und Arzneimittel
US4526988A (en) * 1983-03-10 1985-07-02 Eli Lilly And Company Difluoro antivirals and intermediate therefor

Also Published As

Publication number Publication date
EP0210639B1 (de) 1989-04-19
US4681873A (en) 1987-07-21
EP0210639A3 (en) 1988-02-03
JPS6270387A (ja) 1987-03-31
EP0210639A2 (de) 1987-02-04
DE3662895D1 (en) 1989-05-24

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee