ATE417934T1 - Enzymatisches verfahren zur auflösung enantiomerer gemische von beta-laktamen - Google Patents
Enzymatisches verfahren zur auflösung enantiomerer gemische von beta-laktamenInfo
- Publication number
- ATE417934T1 ATE417934T1 AT00982668T AT00982668T ATE417934T1 AT E417934 T1 ATE417934 T1 AT E417934T1 AT 00982668 T AT00982668 T AT 00982668T AT 00982668 T AT00982668 T AT 00982668T AT E417934 T1 ATE417934 T1 AT E417934T1
- Authority
- AT
- Austria
- Prior art keywords
- beta
- lactams
- dissolving
- enzymatic process
- enantiomeric mixtures
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/16—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing two or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
- C12P41/001—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by metabolizing one of the enantiomers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Wood Science & Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Analytical Chemistry (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US16010399P | 1999-10-18 | 1999-10-18 | |
US09/688,852 US6548293B1 (en) | 1999-10-18 | 2000-10-16 | Enzymatic process for the resolution of enantiomeric mixtures of β-lactams |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE417934T1 true ATE417934T1 (de) | 2009-01-15 |
Family
ID=26856603
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT00982668T ATE417934T1 (de) | 1999-10-18 | 2000-10-17 | Enzymatisches verfahren zur auflösung enantiomerer gemische von beta-laktamen |
Country Status (7)
Country | Link |
---|---|
US (2) | US6548293B1 (de) |
EP (1) | EP1222305B1 (de) |
AT (1) | ATE417934T1 (de) |
AU (1) | AU778711B2 (de) |
CA (1) | CA2386487A1 (de) |
DE (1) | DE60041143D1 (de) |
WO (1) | WO2001029245A2 (de) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6548293B1 (en) * | 1999-10-18 | 2003-04-15 | Fsu Research Foundation, Inc. | Enzymatic process for the resolution of enantiomeric mixtures of β-lactams |
US7126003B2 (en) * | 2001-03-07 | 2006-10-24 | Daiichi Pharmaceutical Co., Ltd. | Method for producing 2-azetidinone derivative |
US20060281918A1 (en) * | 2005-06-10 | 2006-12-14 | Florida State University Research Foundation, Inc. | Resolution of enantiomeric mixtures of beta-lactams |
WO2009118750A1 (en) * | 2008-03-26 | 2009-10-01 | Council Of Scientific & Industrial Research | Stereoselective hydrolysis for the resolution of racemic mixtures of (+/-) -cis-s-acetoxy-l- (4-methoxyphenyl) -4- (2-furyl) -2-azetidinone, (+/-) -cis-s-acetoxy-l- (4-methoxyphenyl) -4- (2-thienyl) -2-azetidinone, or |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5229526A (en) | 1991-09-23 | 1993-07-20 | Florida State University | Metal alkoxides |
DE69333675T2 (de) | 1992-01-15 | 2006-02-02 | E.R. Squibb & Sons, Inc. | Enzymatische Verfahren zur Trennung von Enantiomerengemischen von Verbindungen, die als Zwischenprodukte zur Herstellung von Taxanen nützlich sind |
TW397866B (en) | 1993-07-14 | 2000-07-11 | Bristol Myers Squibb Co | Enzymatic processes for the resolution of enantiomeric mixtures of compounds useful as intermediates in the preparation of taxanes |
US6277626B1 (en) | 1998-02-17 | 2001-08-21 | G.D. Searle & Co. | Process for the enzymatic resolution of lactams |
US6548293B1 (en) * | 1999-10-18 | 2003-04-15 | Fsu Research Foundation, Inc. | Enzymatic process for the resolution of enantiomeric mixtures of β-lactams |
-
2000
- 2000-10-16 US US09/688,852 patent/US6548293B1/en not_active Expired - Lifetime
- 2000-10-17 AU AU19669/01A patent/AU778711B2/en not_active Ceased
- 2000-10-17 DE DE60041143T patent/DE60041143D1/de not_active Expired - Fee Related
- 2000-10-17 CA CA002386487A patent/CA2386487A1/en not_active Abandoned
- 2000-10-17 WO PCT/US2000/041204 patent/WO2001029245A2/en active IP Right Grant
- 2000-10-17 AT AT00982668T patent/ATE417934T1/de not_active IP Right Cessation
- 2000-10-17 EP EP00982668A patent/EP1222305B1/de not_active Expired - Lifetime
-
2003
- 2003-04-11 US US10/412,114 patent/US7067305B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
AU778711B2 (en) | 2004-12-16 |
WO2001029245A2 (en) | 2001-04-26 |
EP1222305A4 (de) | 2003-05-28 |
US20030190743A1 (en) | 2003-10-09 |
CA2386487A1 (en) | 2001-04-26 |
US7067305B2 (en) | 2006-06-27 |
DE60041143D1 (de) | 2009-01-29 |
WO2001029245A8 (en) | 2001-10-04 |
US6548293B1 (en) | 2003-04-15 |
WO2001029245A3 (en) | 2001-06-21 |
AU1966901A (en) | 2001-04-30 |
EP1222305A2 (de) | 2002-07-17 |
EP1222305B1 (de) | 2008-12-17 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DE69333675D1 (de) | Enzymatische Verfahren zur Aüftrennüng von Enantiomeren-Mischungen nützlich als Zwischenprodukte zur Herstellung von Taxanen | |
MX261584B (es) | Proceso para la resolucion enzimatica de una mezcla de enantiomeros | |
DE69925862D1 (de) | Verfahren zur herstellung von azetidinonen | |
DE59811911D1 (de) | Verfahren zur Herstellung von stabilen, feinteiligen Polymerdispersionen | |
DE69826604D1 (de) | Verfahren zur fermentativen herstellung von deacylierten cephalosporinen | |
DK0958281T3 (da) | Opspaltning af ritalinsyresalt | |
DE60018902D1 (de) | Verfahren zur herstellung von nitroxymethylphenylestern von aspirinderivaten | |
ATE417934T1 (de) | Enzymatisches verfahren zur auflösung enantiomerer gemische von beta-laktamen | |
DE69934948D1 (de) | Verfahren zur cooxidation von organischen verbindungen | |
BR9714099A (pt) | Revolução enzimática de ésteres de ácido acético-benzodiazepina com lipase | |
BR0015805B1 (pt) | processo para preparar compostos opticamente ativos, e, composto opticamente ativo. | |
DE60105314D1 (de) | Verfahren zur herstellung von taxanderivaten | |
DE59914298D1 (de) | Verfahren zur Racematspaltung von Arylalkylcarbonsäureestern | |
BR0114884A (pt) | Compostos calcilìticos | |
DE69901388D1 (de) | Verfahren zur herstellung von zwischenprodukten für synthese | |
DE59902242D1 (de) | Verfahren zur Herstellung von Kompost enthaltenden Düngesubstraten | |
DE69819538D1 (de) | Verfahren zur verbesserung der optischen reinheit von 2r-[1-hydroxy-1-trifluormethyl-3-cyclopropylpropyn-2-yl]-4-chloranilin | |
DE60216616D1 (de) | Enzymatisches verfahren zur herstellung von organofluorverbindungen | |
ATE233822T1 (de) | Verfahren zur stereoselektiven herstellung von substituierten cyclohexylcyanhydrinen | |
ATE234809T1 (de) | Verfahren zur herstellung von glucoprotaminen | |
WO2004081220A3 (en) | A process for enzymatically resolving an enantiomeric mixture of alpha-hydroxy acids | |
DE50204211D1 (de) | Verfahren zur enzymatischen Herstellung von enantiomerenreinen 1,3-Dioxolan-4-on- und 1,3-Oxathiolan-5-on-Derivaten | |
DE69733209D1 (de) | Verfahren zur stereoselektiven herstellung von nitro-enamin-verbindungen | |
NO20020328L (no) | Fremgangsmåte for fremstilling av 4-cyano-2-aminometyltiazol | |
SE9901712D0 (sv) | New process |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |