ATE408398T1 - Nanopartikele für dna verabreichung zu einem zielorgan - Google Patents
Nanopartikele für dna verabreichung zu einem zielorganInfo
- Publication number
- ATE408398T1 ATE408398T1 AT02767270T AT02767270T ATE408398T1 AT E408398 T1 ATE408398 T1 AT E408398T1 AT 02767270 T AT02767270 T AT 02767270T AT 02767270 T AT02767270 T AT 02767270T AT E408398 T1 ATE408398 T1 AT E408398T1
- Authority
- AT
- Austria
- Prior art keywords
- nanoparticles
- target organ
- dna administration
- dna
- administration
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
- A61K48/0008—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'non-active' part of the composition delivered, e.g. wherein such 'non-active' part is not delivered simultaneously with the 'active' part of the composition
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5107—Excipients; Inactive ingredients
- A61K9/513—Organic macromolecular compounds; Dendrimers
- A61K9/5138—Organic macromolecular compounds; Dendrimers obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5107—Excipients; Inactive ingredients
- A61K9/513—Organic macromolecular compounds; Dendrimers
- A61K9/5161—Polysaccharides, e.g. alginate, chitosan, cellulose derivatives; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Wood Science & Technology (AREA)
- Nanotechnology (AREA)
- Optics & Photonics (AREA)
- General Engineering & Computer Science (AREA)
- Zoology (AREA)
- Plant Pathology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Manufacturing Of Micro-Capsules (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/EP2002/008434 WO2004017945A1 (en) | 2002-07-29 | 2002-07-29 | Nanoparticles for dna administration to a target organ |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE408398T1 true ATE408398T1 (de) | 2008-10-15 |
Family
ID=31896790
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT02767270T ATE408398T1 (de) | 2002-07-29 | 2002-07-29 | Nanopartikele für dna verabreichung zu einem zielorgan |
Country Status (10)
Country | Link |
---|---|
US (1) | US7402573B2 (de) |
EP (1) | EP1526840B1 (de) |
JP (1) | JP2006500015A (de) |
AT (1) | ATE408398T1 (de) |
AU (1) | AU2002331356A1 (de) |
CA (1) | CA2492807A1 (de) |
DE (1) | DE60229003D1 (de) |
DK (1) | DK1526840T3 (de) |
ES (1) | ES2314097T3 (de) |
WO (1) | WO2004017945A1 (de) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2314097T3 (es) | 2002-07-29 | 2009-03-16 | Nanodel Technologies Gmbh | Nanoparticulas para la administracion de adn a un organo diana. |
PL1796650T3 (pl) * | 2004-09-14 | 2009-06-30 | Nanodel Tech Gmbh | Nanocząstki zawierające dostarczające podłoże |
EP1661559A1 (de) * | 2004-11-25 | 2006-05-31 | NanoDel Technologies GmbH | Verabreichungssystem hergestellt durch ein Miniemulsionsverfahren |
WO2006056362A2 (en) * | 2004-11-25 | 2006-06-01 | Nanodel Technologies Gmbh | Delivery vehicle manufactured by the miniemulsion method |
WO2006130943A1 (en) * | 2005-06-10 | 2006-12-14 | The Governors Of The University Of Alberta | Respirable dried powder formulation comprising drug loaded nanoparticles |
EP1815851A1 (de) * | 2006-02-03 | 2007-08-08 | NanoDel Technologies GmbH | Nanopartikel zur Arzneistoffverabreichung |
EP2029119A2 (de) * | 2006-06-08 | 2009-03-04 | Bayer Schering Pharma Aktiengesellschaft | Funktionalisierte, feste polymernanopartikel für diagnostische und therapeutische anwendungen |
JP4963221B2 (ja) * | 2006-11-24 | 2012-06-27 | 公立大学法人横浜市立大学 | シアノアクリレート系ポリマー粒子及びその製造方法 |
JP5224313B2 (ja) * | 2007-02-27 | 2013-07-03 | 公立大学法人横浜市立大学 | プラスミド送達用粒子 |
RU2617059C2 (ru) * | 2014-11-11 | 2017-04-19 | Федеральное государственное бюджетное научное учреждение "Научно-исследовательский институт вакцин и сывороток им. И.И. Мечникова" (ФГБНУ НИИВС им. И.И. Мечникова) | Способ получения амфифильных блок-сополимеров N,N-диметиламиноэтилметакрилата для доставки нуклеиновых кислот в живые клетки |
JP2020517638A (ja) | 2017-04-20 | 2020-06-18 | エータイアー ファーマ, インコーポレイテッド | 肺の炎症を治療するための組成物および方法 |
DK3615023T3 (da) | 2017-04-25 | 2023-09-25 | Ischemix Llc | Lipoyl-glu-ala til behandlingen af neurodegenerativ skade forårsaget af traumatisk hjerneskade |
CN118063599A (zh) | 2018-07-03 | 2024-05-24 | 吉利德科学公司 | 靶向hiv gp120的抗体和使用方法 |
CR20210687A (es) | 2019-06-25 | 2022-03-03 | Gilead Sciences Inc | PROTEÍNAS DE FUSIÓN FLT3L-Fc Y MÉTODOS DE USO |
CN114761041A (zh) | 2019-07-16 | 2022-07-15 | 吉利德科学公司 | Hiv疫苗及其制备和使用方法 |
KR20220074917A (ko) | 2019-09-30 | 2022-06-03 | 길리애드 사이언시즈, 인코포레이티드 | Hbv 백신 및 hbv를 치료하는 방법 |
CA3128035A1 (en) | 2020-08-13 | 2022-02-13 | Bioasis Technologies, Inc. | Combination therapies for delivery across the blood brain barrier |
TWI815194B (zh) | 2020-10-22 | 2023-09-11 | 美商基利科學股份有限公司 | 介白素2-Fc融合蛋白及使用方法 |
WO2024015741A1 (en) | 2022-07-12 | 2024-01-18 | Gilead Sciences, Inc. | Hiv immunogenic polypeptides and vaccines and uses thereof |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2184242C (en) * | 1994-02-28 | 2000-05-02 | Jorg Kreuter | Drug targeting system, method for preparing same and its use |
US6248720B1 (en) * | 1996-07-03 | 2001-06-19 | Brown University Research Foundation | Method for gene therapy using nucleic acid loaded polymeric microparticles |
WO1997003702A1 (en) * | 1995-07-21 | 1997-02-06 | Brown University Research Foundation | A method for gene therapy using nucleic acid loaded polymeric microparticles |
CA2295177C (en) * | 1997-06-13 | 2007-01-09 | Medinova Medical Consulting Gmbh | Drug targeting system, method of its preparation and its use |
US6265546B1 (en) * | 1997-12-22 | 2001-07-24 | Genset | Prostate cancer gene |
JP2003501379A (ja) * | 1999-06-02 | 2003-01-14 | ナノファーマ アーゲー | ガン治療のための薬剤を充填したナノパーティクルの使用 |
ES2314097T3 (es) | 2002-07-29 | 2009-03-16 | Nanodel Technologies Gmbh | Nanoparticulas para la administracion de adn a un organo diana. |
-
2002
- 2002-07-29 ES ES02767270T patent/ES2314097T3/es not_active Expired - Lifetime
- 2002-07-29 DE DE60229003T patent/DE60229003D1/de not_active Expired - Fee Related
- 2002-07-29 CA CA002492807A patent/CA2492807A1/en not_active Abandoned
- 2002-07-29 EP EP02767270A patent/EP1526840B1/de not_active Expired - Lifetime
- 2002-07-29 DK DK02767270T patent/DK1526840T3/da active
- 2002-07-29 AU AU2002331356A patent/AU2002331356A1/en not_active Abandoned
- 2002-07-29 WO PCT/EP2002/008434 patent/WO2004017945A1/en active IP Right Grant
- 2002-07-29 JP JP2004529738A patent/JP2006500015A/ja active Pending
- 2002-07-29 AT AT02767270T patent/ATE408398T1/de not_active IP Right Cessation
-
2005
- 2005-01-24 US US11/041,606 patent/US7402573B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
WO2004017945A1 (en) | 2004-03-04 |
ES2314097T3 (es) | 2009-03-16 |
CA2492807A1 (en) | 2004-03-04 |
EP1526840B1 (de) | 2008-09-17 |
DE60229003D1 (de) | 2008-10-30 |
US20050175710A1 (en) | 2005-08-11 |
DK1526840T3 (da) | 2008-11-03 |
JP2006500015A (ja) | 2006-01-05 |
EP1526840A1 (de) | 2005-05-04 |
US7402573B2 (en) | 2008-07-22 |
AU2002331356A1 (en) | 2004-03-11 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ATE408398T1 (de) | Nanopartikele für dna verabreichung zu einem zielorgan | |
EP2172549A3 (de) | Rnai expressionskonstrukte | |
RS51213B (sr) | Farmaceutski vaginalni gel koji sadrži tenofovir | |
CY1115525T1 (el) | Συνθεση και χρηση αντι-αντιστροφων φωσφοροθειοϊκων αναλογων της καλυπτρας αγγελιοφορου rna | |
MX2007005200A (es) | Plaquetas a partir de celulas germinales. | |
TR201909609T4 (tr) | Modifiye edilmiş nükleosidleri içeren rna ve kullanım yöntemleri. | |
EP2029754A4 (de) | Magnetosomen-genexpression in eukaryontischen zellen | |
WO2007055905A3 (en) | Compositions and methods of vascular injury repair | |
EP2732819A3 (de) | Verbindungen zur Verstärkung der ATOH-1-Expression | |
EP2446862A3 (de) | Amphiphile Peptide und Hydrogelmatrizen daraus zur Knochenreparatur | |
CY1118073T1 (el) | Συνθεσεις και μεθοδοι για την αυξηση της δρασης της τελομερασης | |
EP2366787A3 (de) | Codonoptimierte IL-15- und IL-15R-Alpha-Gene zur Expression von Säugetierzellen | |
GB2472964A (en) | Vectors for delivery of light-sensitive proteins and methods of use | |
WO2008118392A3 (en) | Synthetic cell platforms and methods of use thereof | |
WO2003093469A3 (en) | Methods for delivering nucleic acid molecules into cells and assessment thereof | |
NZ592688A (en) | Modified blood factors comprising a low degree of water soluble polymer | |
EP1987165A4 (de) | Gene mit einfluss auf die menschliche gedächtnisleistung | |
WO2004094610A3 (en) | Wnt as a factor for cardiac myogenesis | |
NO20070780L (no) | Celloverflateprotein. | |
WO2006128885A3 (en) | Uses of oligonucleotides stimulatory of the mesenchymal stem cell proliferation | |
WO2004099364A3 (en) | Multicellular compositions of pluripotent human embryonic stem cells and cancer cells | |
CA2441535A1 (en) | Methods for delivering nucleic acid molecules into cells and assessment thereof | |
WO2006042005A3 (en) | Global gene expression profiling of circulating tumor cells | |
ATE239749T1 (de) | Phosphor-enthaltende dendrimere als transfektionsagente | |
NO20063715L (no) | Syntese av spongosin |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties | ||
REN | Ceased due to non-payment of the annual fee |