ATE406917T1 - Zusammensetzung, enthaltend feine teilchen als träger von biologischen wirkstoffen, und herstellungsverfahren dafür - Google Patents
Zusammensetzung, enthaltend feine teilchen als träger von biologischen wirkstoffen, und herstellungsverfahren dafürInfo
- Publication number
- ATE406917T1 ATE406917T1 AT02796357T AT02796357T ATE406917T1 AT E406917 T1 ATE406917 T1 AT E406917T1 AT 02796357 T AT02796357 T AT 02796357T AT 02796357 T AT02796357 T AT 02796357T AT E406917 T1 ATE406917 T1 AT E406917T1
- Authority
- AT
- Austria
- Prior art keywords
- carrier
- fine particles
- production method
- composition containing
- active ingredients
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
- A61K47/645—Polycationic or polyanionic oligopeptides, polypeptides or polyamino acids, e.g. polylysine, polyarginine, polyglutamic acid or peptide TAT
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
- A61K47/6921—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a particulate, a powder, an adsorbate, a bead or a sphere
- A61K47/6927—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a particulate, a powder, an adsorbate, a bead or a sphere the form being a solid microparticle having no hollow or gas-filled cores
- A61K47/6929—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a particulate, a powder, an adsorbate, a bead or a sphere the form being a solid microparticle having no hollow or gas-filled cores the form being a nanoparticle, e.g. an immuno-nanoparticle
- A61K47/6931—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a particulate, a powder, an adsorbate, a bead or a sphere the form being a solid microparticle having no hollow or gas-filled cores the form being a nanoparticle, e.g. an immuno-nanoparticle the material constituting the nanoparticle being a polymer
- A61K47/6935—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a particulate, a powder, an adsorbate, a bead or a sphere the form being a solid microparticle having no hollow or gas-filled cores the form being a nanoparticle, e.g. an immuno-nanoparticle the material constituting the nanoparticle being a polymer the polymer being obtained otherwise than by reactions involving carbon to carbon unsaturated bonds, e.g. polyesters, polyamides or polyglycerol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1611—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Nanotechnology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Inorganic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Processes Of Treating Macromolecular Substances (AREA)
- Other Resins Obtained By Reactions Not Involving Carbon-To-Carbon Unsaturated Bonds (AREA)
- Dry Development In Electrophotography (AREA)
- Electrophotography Configuration And Component (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2001256125 | 2001-08-27 |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE406917T1 true ATE406917T1 (de) | 2008-09-15 |
Family
ID=19083982
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT02796357T ATE406917T1 (de) | 2001-08-27 | 2002-08-27 | Zusammensetzung, enthaltend feine teilchen als träger von biologischen wirkstoffen, und herstellungsverfahren dafür |
Country Status (7)
Country | Link |
---|---|
US (1) | US7897176B2 (de) |
EP (1) | EP1431347B1 (de) |
JP (2) | JP2003523544A (de) |
AT (1) | ATE406917T1 (de) |
CA (1) | CA2458837C (de) |
DE (1) | DE60228742D1 (de) |
WO (1) | WO2003018690A1 (de) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2003083478A1 (fr) * | 2002-04-03 | 2003-10-09 | Japan Science And Technology Agency | Face de capteur pour biopuce porteuse de nanoparticules de polyethylene glycolate |
WO2007116965A1 (ja) * | 2006-04-12 | 2007-10-18 | Toray Industries, Inc. | グラフトポリマーとカルシウム化合物とを含む微粒子 |
EP2082754A4 (de) * | 2006-11-11 | 2012-10-31 | Univ Tokyo | Knochendefekt-füller, träger mit kontrollierter freisetzung und ihre produktionsverfahren |
JP5081439B2 (ja) * | 2006-12-07 | 2012-11-28 | 独立行政法人科学技術振興機構 | 造影剤含有有機−無機ハイブリッド型粒子 |
CA2682135A1 (en) * | 2007-04-17 | 2008-10-30 | Baxter International Inc. | Nucleic acid microparticles for pulmonary delivery |
JP2011010549A (ja) * | 2007-10-29 | 2011-01-20 | Univ Of Tokyo | ポリエチレングリコールの結合した核酸のコンジュゲートとリン酸カルシウムの有機−無機ハイブリッド型ナノ粒子 |
JP2010018772A (ja) * | 2008-01-25 | 2010-01-28 | Ebara Corp | ペグ修飾ハイドロキシアパタイト及びそれを基材とする医薬とその製造方法 |
US8309134B2 (en) * | 2008-10-03 | 2012-11-13 | Southwest Research Institute | Modified calcium phosphate nanoparticle formation |
EP2457588A1 (de) | 2010-11-05 | 2012-05-30 | UMC Utrecht Holding B.V. | Mikrosphäre mit Lanthanid-Metallkomplex |
CN113908137B (zh) * | 2021-10-27 | 2023-04-11 | 高州市人民医院 | 一种注射用硬核软膜型纳米缓释递药系统的制备方法 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH0517111A (ja) | 1991-02-21 | 1993-01-26 | Ricoh Co Ltd | 水酸アパタイト超微粒子 |
US5368869A (en) * | 1993-03-09 | 1994-11-29 | Utah State University Foundation | Compositions and methods for manufacturing a skim or lowfat milk product with increased creaminess, color, mouthfeel, and taste sensations similar to milk with a higher fat content |
US6436386B1 (en) * | 2000-11-14 | 2002-08-20 | Shearwater Corporation | Hydroxyapatite-targeting poly (ethylene glycol) and related polymers |
US6939564B2 (en) | 2001-06-08 | 2005-09-06 | Labopharm, Inc. | Water-soluble stabilized self-assembled polyelectrolytes |
US7094810B2 (en) | 2001-06-08 | 2006-08-22 | Labopharm, Inc. | pH-sensitive block copolymers for pharmaceutical compositions |
KR100566911B1 (ko) * | 2001-06-25 | 2006-04-03 | 주식회사 삼양사 | 약물 전달체용 음이온기-함유 양친성 블록 공중합체 및 그의 양이온성 약물과의 복합체 |
-
2001
- 2001-02-14 JP JP2001560747A patent/JP2003523544A/ja active Pending
-
2002
- 2002-08-27 CA CA002458837A patent/CA2458837C/en not_active Expired - Fee Related
- 2002-08-27 US US10/487,713 patent/US7897176B2/en not_active Expired - Fee Related
- 2002-08-27 EP EP02796357A patent/EP1431347B1/de not_active Expired - Lifetime
- 2002-08-27 WO PCT/JP2002/008619 patent/WO2003018690A1/ja active IP Right Grant
- 2002-08-27 DE DE60228742T patent/DE60228742D1/de not_active Expired - Lifetime
- 2002-08-27 AT AT02796357T patent/ATE406917T1/de not_active IP Right Cessation
- 2002-08-27 JP JP2003523544A patent/JP4641721B2/ja not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
JPWO2003018690A1 (ja) | 2004-12-09 |
JP2003523544A (ja) | 2003-08-05 |
CA2458837C (en) | 2009-12-15 |
US7897176B2 (en) | 2011-03-01 |
US20040197360A1 (en) | 2004-10-07 |
CA2458837A1 (en) | 2003-03-06 |
JP4641721B2 (ja) | 2011-03-02 |
WO2003018690A1 (fr) | 2003-03-06 |
EP1431347B1 (de) | 2008-09-03 |
EP1431347A4 (de) | 2006-08-30 |
EP1431347A1 (de) | 2004-06-23 |
DE60228742D1 (de) | 2008-10-16 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |