ATE401411T1 - ßFROG-PRINCEß - EIN TRANSPOSONVEKTOR FÜR DEN GENTRANSFER BEI WIRBELTIEREN - Google Patents
ßFROG-PRINCEß - EIN TRANSPOSONVEKTOR FÜR DEN GENTRANSFER BEI WIRBELTIERENInfo
- Publication number
- ATE401411T1 ATE401411T1 AT03732512T AT03732512T ATE401411T1 AT E401411 T1 ATE401411 T1 AT E401411T1 AT 03732512 T AT03732512 T AT 03732512T AT 03732512 T AT03732512 T AT 03732512T AT E401411 T1 ATE401411 T1 AT E401411T1
- Authority
- AT
- Austria
- Prior art keywords
- transposon
- selectable marker
- gene
- integration system
- based dna
- Prior art date
Links
- 108090000623 proteins and genes Proteins 0.000 title abstract 6
- 241000251539 Vertebrata <Metazoa> Species 0.000 title abstract 2
- 230000010354 integration Effects 0.000 abstract 5
- 239000003550 marker Substances 0.000 abstract 4
- 108091033319 polynucleotide Proteins 0.000 abstract 4
- 102000040430 polynucleotide Human genes 0.000 abstract 4
- 239000002157 polynucleotide Substances 0.000 abstract 4
- 102000008579 Transposases Human genes 0.000 abstract 3
- 108010020764 Transposases Proteins 0.000 abstract 3
- 238000000034 method Methods 0.000 abstract 3
- 108091030071 RNAI Proteins 0.000 abstract 2
- 230000009368 gene silencing by RNA Effects 0.000 abstract 2
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 abstract 1
- 230000004568 DNA-binding Effects 0.000 abstract 1
- 108020004459 Small interfering RNA Proteins 0.000 abstract 1
- 239000004055 small Interfering RNA Substances 0.000 abstract 1
- 238000013518 transcription Methods 0.000 abstract 1
- 230000035897 transcription Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
- C12N15/90—Stable introduction of foreign DNA into chromosome
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2800/00—Nucleic acids vectors
- C12N2800/60—Vectors containing traps for, e.g. exons, promoters
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2800/00—Nucleic acids vectors
- C12N2800/90—Vectors containing a transposable element
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2840/00—Vectors comprising a special translation-regulating system
- C12N2840/44—Vectors comprising a special translation-regulating system being a specific part of the splice mechanism, e.g. donor, acceptor
Landscapes
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Mycology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10224242A DE10224242A1 (de) | 2002-05-29 | 2002-05-29 | Frog Prince, ein Transposonvektor für den Gentransfer bei Wirbeltieren |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE401411T1 true ATE401411T1 (de) | 2008-08-15 |
Family
ID=29432501
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT03732512T ATE401411T1 (de) | 2002-05-29 | 2003-05-30 | ßFROG-PRINCEß - EIN TRANSPOSONVEKTOR FÜR DEN GENTRANSFER BEI WIRBELTIEREN |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20050241007A1 (de) |
| EP (1) | EP1507865B1 (de) |
| JP (1) | JP4493492B2 (de) |
| AT (1) | ATE401411T1 (de) |
| AU (1) | AU2003238444A1 (de) |
| DE (2) | DE10224242A1 (de) |
| DK (1) | DK1507865T3 (de) |
| WO (1) | WO2003100070A2 (de) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5320546B2 (ja) | 2006-12-13 | 2013-10-23 | 国立大学法人名古屋大学 | Ｔｏｌ１因子のトランスポザーゼ及びそれを用いたＤＮＡ導入システム |
| HU0700675D0 (en) | 2007-10-15 | 2007-12-28 | Mta Tamogatott Kutatohelyek Ir | Method for monitoring stem cell differentiation |
| EP2067402A1 (de) | 2007-12-07 | 2009-06-10 | Max Delbrück Centrum für Molekulare Medizin (MDC) Berlin-Buch; | Transposon-vermittelte Mutagenese in Spermatogoniestammzellen |
| WO2010008562A2 (en) | 2008-07-16 | 2010-01-21 | Recombinetics | Methods and materials for producing transgenic animals |
| US20100105140A1 (en) * | 2008-07-16 | 2010-04-29 | Fahrenkrug Scott C | Plaice dna transposon system |
| EP2539450B1 (de) * | 2010-02-25 | 2016-02-17 | Advanced Liquid Logic, Inc. | Verfahren zur herstellung von nukleinsäure-bibliotheken |
| US20110312001A1 (en) | 2010-06-15 | 2011-12-22 | Emile Nuwaysir | Compendium of ready-built stem cell models for interrogation of biological response |
| CA2804595C (en) | 2010-07-07 | 2018-11-13 | Cellular Dynamics International, Inc. | Endothelial cell production by programming |
| EP2601289B1 (de) | 2010-08-04 | 2017-07-12 | Cellular Dynamics International, Inc. | Neuprogrammierung immortalisierter b-zellen |
| EP2673358B1 (de) | 2011-02-08 | 2019-01-09 | FUJIFILM Cellular Dynamics, Inc. | Herstellung blutbildender vorläuferzellen durch programmierung |
| EP2732029B1 (de) | 2011-07-11 | 2019-01-16 | FUJIFILM Cellular Dynamics, Inc. | Verfahren zur zellprogrammierung und genommanipulation |
| JP2016508726A (ja) | 2013-02-22 | 2016-03-24 | セルラー ダイナミクス インターナショナル， インコーポレイテッド | 組み合わせた遺伝的および化学的操作によるフォワードプログラミングを介した肝細胞の産生 |
| US20160010094A1 (en) | 2013-03-01 | 2016-01-14 | University Of Pretoria | Transgenic cell selection |
| US20170107486A1 (en) | 2014-04-21 | 2017-04-20 | Cellular Dynamics International, Inc. | Hepatocyte production via forward programming by combined genetic and chemical engineering |
| EP3365435B1 (de) | 2015-10-20 | 2021-01-13 | FUJIFILM Cellular Dynamics, Inc. | Herstellung von hämatopoitischen vorläuferzellen mit mehreren abstammungslinien durch genetische programmierung |
| GB201518910D0 (en) | 2015-10-26 | 2015-12-09 | Rieke Packaging Systems Ltd | Dispensers |
| WO2017096363A1 (en) | 2015-12-04 | 2017-06-08 | Board Of Regents, The University Of Texas System | Reporter system for detecting and targeting activated cells |
| WO2018067826A1 (en) | 2016-10-05 | 2018-04-12 | Cellular Dynamics International, Inc. | Generating mature lineages from induced pluripotent stem cells with mecp2 disruption |
| KR102598351B1 (ko) | 2016-10-05 | 2023-11-08 | 후지필름 셀룰러 다이내믹스, 인코포레이티드 | 만능 줄기 세포를 hla 동형 접합 면역 세포로 직접 분화시키기 위한 방법 |
| EP4083063A3 (de) | 2017-04-18 | 2023-01-04 | FUJIFILM Cellular Dynamics, Inc. | Antigenspezifische immuneffektorzellen |
| US11649455B2 (en) | 2018-03-30 | 2023-05-16 | University Of Geneva | Micro RNA expression constructs and uses thereof |
| US20220257796A1 (en) | 2019-07-02 | 2022-08-18 | Fred Hutchinson Cancer Research Center | Recombinant ad35 vectors and related gene therapy improvements |
| US20230144097A1 (en) * | 2020-03-30 | 2023-05-11 | Institute Of Zoology, Chinese Academy Of Sciences | Active dna transposon systems and methods for use thereof |
| CA3179599A1 (en) | 2020-05-27 | 2021-12-02 | Marco ALESSANDRINI | Adapter molecules to re-direct car t cells to an antigen of interest |
| CN117242173A (zh) | 2021-05-03 | 2023-12-15 | 安斯泰来再生医药协会 | 产生成熟角膜内皮细胞的方法 |
| AU2022270117A1 (en) | 2021-05-07 | 2023-11-02 | Astellas Institute For Regenerative Medicine | Methods of generating mature hepatocytes |
| GB202206507D0 (en) | 2022-05-04 | 2022-06-15 | Antion Biosciences Sa | Expression construct |
| GB202306619D0 (en) | 2023-05-04 | 2023-06-21 | Antion Biosciences Sa | Cell |
| GB202402745D0 (en) | 2024-02-27 | 2024-04-10 | Antion Biosciences Sa | Cell |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6489458B2 (en) * | 1997-03-11 | 2002-12-03 | Regents Of The University Of Minnesota | DNA-based transposon system for the introduction of nucleic acid into DNA of a cell |
| JP2001523450A (ja) * | 1997-11-13 | 2001-11-27 | リージェンツ・オブ・ザ・ユニバーシティ・オブ・ミネソタ | 細胞のｄｎａへの核酸の導入のための核酸転移ベクター |
-
2002
- 2002-05-29 DE DE10224242A patent/DE10224242A1/de not_active Withdrawn
-
2003
- 2003-05-30 EP EP03732512A patent/EP1507865B1/de not_active Expired - Lifetime
- 2003-05-30 JP JP2004507510A patent/JP4493492B2/ja not_active Expired - Fee Related
- 2003-05-30 DE DE60322214T patent/DE60322214D1/de not_active Expired - Lifetime
- 2003-05-30 AT AT03732512T patent/ATE401411T1/de not_active IP Right Cessation
- 2003-05-30 AU AU2003238444A patent/AU2003238444A1/en not_active Abandoned
- 2003-05-30 US US10/515,405 patent/US20050241007A1/en not_active Abandoned
- 2003-05-30 WO PCT/EP2003/005707 patent/WO2003100070A2/en not_active Ceased
- 2003-05-30 DK DK03732512T patent/DK1507865T3/da active
Also Published As
| Publication number | Publication date |
|---|---|
| AU2003238444A8 (en) | 2003-12-12 |
| JP2005527216A (ja) | 2005-09-15 |
| JP4493492B2 (ja) | 2010-06-30 |
| EP1507865B1 (de) | 2008-07-16 |
| AU2003238444A1 (en) | 2003-12-12 |
| WO2003100070A2 (en) | 2003-12-04 |
| DK1507865T3 (da) | 2008-10-13 |
| DE60322214D1 (de) | 2008-08-28 |
| EP1507865A2 (de) | 2005-02-23 |
| US20050241007A1 (en) | 2005-10-27 |
| DE10224242A1 (de) | 2003-12-11 |
| WO2003100070A3 (en) | 2004-12-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |