ATE401322T1 - Imidazolderivate als faktor-xa-inhibitoren - Google Patents
Imidazolderivate als faktor-xa-inhibitorenInfo
- Publication number
- ATE401322T1 ATE401322T1 AT03778324T AT03778324T ATE401322T1 AT E401322 T1 ATE401322 T1 AT E401322T1 AT 03778324 T AT03778324 T AT 03778324T AT 03778324 T AT03778324 T AT 03778324T AT E401322 T1 ATE401322 T1 AT E401322T1
- Authority
- AT
- Austria
- Prior art keywords
- inhibitors
- factor
- imidazole derivatives
- imidazole
- derivatives
- Prior art date
Links
- RAXXELZNTBOGNW-UHFFFAOYSA-N 1H-imidazole Chemical class C1=CNC=N1 RAXXELZNTBOGNW-UHFFFAOYSA-N 0.000 title 1
- 229940123583 Factor Xa inhibitor Drugs 0.000 title 1
- 229940079865 intestinal antiinfectives imidazole derivative Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP02027120A EP1426364A1 (en) | 2002-12-04 | 2002-12-04 | Imidazole-derivatives as factor Xa inhibitors |
| EP03011307A EP1479674A1 (en) | 2003-05-19 | 2003-05-19 | Imidiazole-derivatives as factor xa inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE401322T1 true ATE401322T1 (de) | 2008-08-15 |
Family
ID=32471891
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT03778324T ATE401322T1 (de) | 2002-12-04 | 2003-11-20 | Imidazolderivate als faktor-xa-inhibitoren |
Country Status (12)
| Country | Link |
|---|---|
| EP (1) | EP1569927B1 (enExample) |
| JP (1) | JP4504820B2 (enExample) |
| AR (1) | AR042261A1 (enExample) |
| AT (1) | ATE401322T1 (enExample) |
| AU (1) | AU2003285336B2 (enExample) |
| BR (1) | BR0317003A (enExample) |
| CA (1) | CA2507624A1 (enExample) |
| DE (1) | DE60322254D1 (enExample) |
| MX (1) | MXPA05005498A (enExample) |
| PE (1) | PE20040700A1 (enExample) |
| TW (1) | TW200504027A (enExample) |
| WO (1) | WO2004050636A2 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI372050B (en) | 2003-07-03 | 2012-09-11 | Astex Therapeutics Ltd | (morpholin-4-ylmethyl-1h-benzimidazol-2-yl)-1h-pyrazoles |
| WO2006047415A2 (en) | 2004-10-26 | 2006-05-04 | Janssen Pharmaceutica, N.V. | Factor xa compounds |
| US8110573B2 (en) | 2004-12-30 | 2012-02-07 | Astex Therapeutics Limited | Pyrazole compounds that modulate the activity of CDK, GSK and aurora kinases |
| JP5474354B2 (ja) | 2005-12-30 | 2014-04-16 | アステックス、セラピューティックス、リミテッド | 医薬化合物 |
| JP5523829B2 (ja) | 2006-06-29 | 2014-06-18 | アステックス、セラピューティックス、リミテッド | 複合薬剤 |
| WO2009105504A2 (en) | 2008-02-21 | 2009-08-27 | Schering Corporation | Functionally selective alpha2c adrenoreceptor agonists |
| JP5996532B2 (ja) | 2010-07-15 | 2016-09-21 | バイエル・インテレクチュアル・プロパティ・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツングＢａｙｅｒ Ｉｎｔｅｌｌｅｃｔｕａｌ Ｐｒｏｐｅｒｔｙ ＧｍｂＨ | 有害生物防除剤としての新規複素環式化合物 |
| CN114105881B (zh) * | 2020-08-31 | 2024-01-26 | 沈阳海诺威医药科技有限公司 | 血小板聚集抑制剂及其制备方法和用途 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6020357A (en) * | 1996-12-23 | 2000-02-01 | Dupont Pharmaceuticals Company | Nitrogen containing heteroaromatics as factor Xa inhibitors |
| WO2001032628A1 (en) * | 1999-11-03 | 2001-05-10 | Bristol-Myers Squibb Pharma Company | Cyano compounds as factor xa inhibitors |
| WO2002000651A2 (en) * | 2000-06-27 | 2002-01-03 | Bristol-Myers Squibb Pharma Company | Factor xa inhibitors |
-
2003
- 2003-11-20 EP EP03778324A patent/EP1569927B1/en not_active Expired - Lifetime
- 2003-11-20 AT AT03778324T patent/ATE401322T1/de not_active IP Right Cessation
- 2003-11-20 BR BR0317003-9A patent/BR0317003A/pt unknown
- 2003-11-20 MX MXPA05005498A patent/MXPA05005498A/es unknown
- 2003-11-20 DE DE60322254T patent/DE60322254D1/de not_active Expired - Lifetime
- 2003-11-20 WO PCT/EP2003/012996 patent/WO2004050636A2/en not_active Ceased
- 2003-11-20 CA CA002507624A patent/CA2507624A1/en not_active Abandoned
- 2003-11-20 AU AU2003285336A patent/AU2003285336B2/en not_active Ceased
- 2003-11-20 JP JP2004570676A patent/JP4504820B2/ja not_active Expired - Fee Related
- 2003-11-24 PE PE2003001185A patent/PE20040700A1/es not_active Application Discontinuation
- 2003-12-02 TW TW092133762A patent/TW200504027A/zh unknown
- 2003-12-02 AR ARP030104430A patent/AR042261A1/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| BR0317003A (pt) | 2005-10-25 |
| AU2003285336A1 (en) | 2004-06-23 |
| WO2004050636A3 (en) | 2004-10-14 |
| EP1569927B1 (en) | 2008-07-16 |
| WO2004050636A2 (en) | 2004-06-17 |
| TW200504027A (en) | 2005-02-01 |
| JP4504820B2 (ja) | 2010-07-14 |
| EP1569927A2 (en) | 2005-09-07 |
| CA2507624A1 (en) | 2004-06-17 |
| PE20040700A1 (es) | 2004-11-25 |
| AR042261A1 (es) | 2005-06-15 |
| JP2006514093A (ja) | 2006-04-27 |
| MXPA05005498A (es) | 2005-07-25 |
| DE60322254D1 (de) | 2008-08-28 |
| AU2003285336B2 (en) | 2009-11-26 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE444292T1 (de) | Pyrazolderivate als faktor-xa-inhibitoren | |
| DE60315862D1 (de) | Dihydropyridinonderivate als hne-inhibitoren | |
| DE60330227D1 (de) | N3-alkylierte benzimidazol-derivate als mek-hemmer | |
| DE60329282D1 (de) | Cyano-pyrrolidine als DPP-IV Inhibitoren | |
| ATE416171T1 (de) | 2-hydroxy-3-heteroarylindole derivate als gsk3 inhibitoren | |
| ATE452891T1 (de) | Pyrimidopyrimidone als kinaseinhibitoren | |
| ATE489387T1 (de) | Pyridoä2,1-aü-isochinolinderivate als dpp-iv inhibitoren | |
| ATE426599T1 (de) | Thiazolylpiperidin derivate als mtp inhibitoren | |
| IS7625A (is) | Nýjar samrunnar imídazól afleiður | |
| ATE404564T1 (de) | Diazepinoindolderivate als kinaseinhibitoren | |
| ATE437876T1 (de) | Hexahydropyridoisochinoline als dpp-iv- inhibitoren | |
| DE60315516D1 (de) | Pyridazinon-derivate als cdk2-hemmer | |
| DE60313872D1 (de) | Pyrazoloä1,5-aüpyrimidine als hemmstoffe cyclin-abhängiger kinasen | |
| DK1490355T3 (da) | Indolylmaleimidderivater | |
| ATE400271T1 (de) | Aryl-pyridinderivate als 11-beta-hsd1-hemmer | |
| DE602004024420D1 (de) | Chinazolinderivate als antitumormittel | |
| DE602004008303D1 (de) | Triazolopyrimidinderivate als inhibitoren von glycogensynthasekinase-3 | |
| ATE529428T1 (de) | Thioxanthinderivate als myeloperoxidaseinhibitoren | |
| DE60308670D1 (de) | Substituierte indole als alpha-1 agonisten | |
| ATE420076T1 (de) | Indozolonderivate als 11b-hsd1-inhibitoren | |
| ATE393159T1 (de) | Heterobicyclische pyrazolderivate als kinaseinhibitoren | |
| ATE538787T1 (de) | Benzimidazol-derivative als raf-kinase-hemmer | |
| DE60203529D1 (de) | Indolderivate als cox-ii-inhibitoren | |
| ATE402700T1 (de) | Glycinamid-derivate als raf-kinase-hemmer | |
| ATE386737T1 (de) | Imidazol-derivate als tafia-inhibitoren |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |