ATE399T1 - 7-alpha-methyl-oestrogene, verfahren zu deren herstellung und deren verwendung zur weiterverarbeitung. - Google Patents

7-alpha-methyl-oestrogene, verfahren zu deren herstellung und deren verwendung zur weiterverarbeitung.

Info

Publication number
ATE399T1
ATE399T1 AT79102371T AT79102371T ATE399T1 AT E399 T1 ATE399 T1 AT E399T1 AT 79102371 T AT79102371 T AT 79102371T AT 79102371 T AT79102371 T AT 79102371T AT E399 T1 ATE399 T1 AT E399T1
Authority
AT
Austria
Prior art keywords
general formula
denotes
compound
see diagramm
group
Prior art date
Application number
AT79102371T
Other languages
English (en)
Inventor
Ulrich Dr. Eder
Gregor Dr. Haffer
Guenter Dr. Neef
Gerhard Dr. Sauer
Rudolf Prof. Dr. Wiechert
Original Assignee
Schering Aktiengesellschaft Berlin Und Bergkamen
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Aktiengesellschaft Berlin Und Bergkamen filed Critical Schering Aktiengesellschaft Berlin Und Bergkamen
Application granted granted Critical
Publication of ATE399T1 publication Critical patent/ATE399T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0051—Estrane derivatives
    • C07J1/0066—Estrane derivatives substituted in position 17 beta not substituted in position 17 alfa
    • C07J1/007—Estrane derivatives substituted in position 17 beta not substituted in position 17 alfa the substituent being an OH group free esterified or etherified
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
    • C07C309/63—Esters of sulfonic acids
    • C07C309/72—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C309/73—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton to carbon atoms of non-condensed six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C41/00—Preparation of ethers; Preparation of compounds having groups, groups or groups
    • C07C41/01—Preparation of ethers
    • C07C41/18—Preparation of ethers by reactions not forming ether-oxygen bonds
    • C07C41/26—Preparation of ethers by reactions not forming ether-oxygen bonds by introduction of hydroxy or O-metal groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
    • C07C43/23—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing hydroxy or O-metal groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/62—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by hydrogenation of carbon-to-carbon double or triple bonds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
  • Materials For Photolithography (AREA)
AT79102371T 1978-07-21 1979-07-11 7-alpha-methyl-oestrogene, verfahren zu deren herstellung und deren verwendung zur weiterverarbeitung. ATE399T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19782832604 DE2832604A1 (de) 1978-07-21 1978-07-21 Verfahren zur herstellung von 7 alpha -methyl-oestrogenen
EP79102371A EP0007516B1 (de) 1978-07-21 1979-07-11 7-Alpha-Methyl-Östrogene, Verfahren zu deren Herstellung und deren Verwendung zur Weiterverarbeitung

Publications (1)

Publication Number Publication Date
ATE399T1 true ATE399T1 (de) 1981-11-15

Family

ID=6045334

Family Applications (1)

Application Number Title Priority Date Filing Date
AT79102371T ATE399T1 (de) 1978-07-21 1979-07-11 7-alpha-methyl-oestrogene, verfahren zu deren herstellung und deren verwendung zur weiterverarbeitung.

Country Status (3)

Country Link
EP (1) EP0007516B1 (de)
AT (1) ATE399T1 (de)
DE (2) DE2832604A1 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4386205A (en) * 1981-10-22 1983-05-31 Pfizer Inc. Resolution of racemic 5-phenyl-2-pentanol

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1443082B1 (de) * 1959-09-25 1971-03-25 Herchel Smith Tetracyclische Dienketone
FR1374699A (fr) * 1963-11-08 1964-10-09 Aspro Nicholas Ltd Synthèse des 3-éthers de la delta 8, 14-bis dehydro-oestrone
US3524886A (en) * 1967-12-04 1970-08-18 Syntex Corp Novel phosphonium halides
US4066674A (en) * 1975-11-12 1978-01-03 Schering Aktiengesellschaft Process for the preparation of 1,3-oxygenated 8α-estratrienes and novel intermediates obtained therefrom

Also Published As

Publication number Publication date
EP0007516A3 (en) 1980-04-30
EP0007516A2 (de) 1980-02-06
DE2832604A1 (de) 1980-01-31
DE2961162D1 (en) 1982-01-07
EP0007516B1 (de) 1981-10-28

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Legal Events

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