ATE394107T1 - Vorbeugung und behandlung von kolonadenom oder kolonmikroadenom mit 6-fluorursodeoxycholsäure - Google Patents
Vorbeugung und behandlung von kolonadenom oder kolonmikroadenom mit 6-fluorursodeoxycholsäureInfo
- Publication number
- ATE394107T1 ATE394107T1 AT97925934T AT97925934T ATE394107T1 AT E394107 T1 ATE394107 T1 AT E394107T1 AT 97925934 T AT97925934 T AT 97925934T AT 97925934 T AT97925934 T AT 97925934T AT E394107 T1 ATE394107 T1 AT E394107T1
- Authority
- AT
- Austria
- Prior art keywords
- colon
- prevention
- treatment
- acid
- microadenoma
- Prior art date
Links
- 230000002265 prevention Effects 0.000 title abstract 3
- 239000002253 acid Substances 0.000 title abstract 2
- 206010048832 Colon adenoma Diseases 0.000 title 1
- 210000001072 colon Anatomy 0.000 title 1
- 238000000034 method Methods 0.000 abstract 3
- 208000003200 Adenoma Diseases 0.000 abstract 1
- 206010001233 Adenoma benign Diseases 0.000 abstract 1
- 206010009944 Colon cancer Diseases 0.000 abstract 1
- 208000001333 Colorectal Neoplasms Diseases 0.000 abstract 1
- 241000124008 Mammalia Species 0.000 abstract 1
- 239000003613 bile acid Substances 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 231100000357 carcinogen Toxicity 0.000 abstract 1
- 239000003183 carcinogenic agent Substances 0.000 abstract 1
- 231100000433 cytotoxic Toxicity 0.000 abstract 1
- 230000001472 cytotoxic effect Effects 0.000 abstract 1
- KXGVEGMKQFWNSR-LLQZFEROSA-N deoxycholic acid Chemical compound C([C@H]1CC2)[C@H](O)CC[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CC[C@H]([C@@H](CCC(O)=O)C)[C@@]2(C)[C@@H](O)C1 KXGVEGMKQFWNSR-LLQZFEROSA-N 0.000 abstract 1
- 229960003964 deoxycholic acid Drugs 0.000 abstract 1
- KXGVEGMKQFWNSR-UHFFFAOYSA-N deoxycholic acid Natural products C1CC2CC(O)CCC2(C)C2C1C1CCC(C(CCC(O)=O)C)C1(C)C(O)C2 KXGVEGMKQFWNSR-UHFFFAOYSA-N 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US1820296P | 1996-05-23 | 1996-05-23 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE394107T1 true ATE394107T1 (de) | 2008-05-15 |
Family
ID=21786767
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT97925934T ATE394107T1 (de) | 1996-05-23 | 1997-05-22 | Vorbeugung und behandlung von kolonadenom oder kolonmikroadenom mit 6-fluorursodeoxycholsäure |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US6426340B1 (2) |
| EP (1) | EP0906106B1 (2) |
| JP (2) | JP2000510858A (2) |
| AT (1) | ATE394107T1 (2) |
| AU (1) | AU3091597A (2) |
| CA (1) | CA2253593C (2) |
| DE (1) | DE69738667D1 (2) |
| ES (1) | ES2306459T3 (2) |
| PT (1) | PT906106E (2) |
| WO (1) | WO1997044043A1 (2) |
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU758679B2 (en) * | 1998-07-24 | 2003-03-27 | Seo Hong Yoo | Preparation of aqueous clear solution dosage forms with bile acids |
| EP1105141B1 (de) * | 1998-08-06 | 2003-11-05 | Wolfgang Stremmel | Phosphatidylcholin als arzneimittel mit schleimhautschützender wirkung |
| RS50303B (sr) * | 1999-09-28 | 2009-09-08 | Panacea Biotec Limited, | Farmaceutska kompozicija nimesulida sa kontrolisanim oslobađanjem |
| US7053076B2 (en) | 2001-08-29 | 2006-05-30 | Xenoport, Inc. | Bile-acid derived compounds for enhancing oral absorption and systemic bioavailability of drugs |
| AU2003287300A1 (en) * | 2002-11-01 | 2004-06-07 | James Kaput | Identification of diet-regulated disease-associated genes |
| WO2008088836A2 (en) * | 2007-01-16 | 2008-07-24 | The Burnham Institute For Medical Research | Compositions and methods for treatment of colorectal cancer |
| EP2255813A1 (en) * | 2009-05-29 | 2010-12-01 | The Royal College of Surgeons in Ireland | Derivatives of ursodeoxycholic acid for the treatment of diarrhoea |
| PL3400944T3 (pl) | 2010-11-04 | 2020-11-16 | Albireo Ab | Inhibitory ibat w leczeniu chorób wątroby |
| CA2952406A1 (en) | 2014-06-25 | 2015-12-30 | Ea Pharma Co., Ltd. | Solid formulation and method for preventing or reducing coloration thereof |
| US10441604B2 (en) | 2016-02-09 | 2019-10-15 | Albireo Ab | Cholestyramine pellets and methods for preparation thereof |
| US10441605B2 (en) | 2016-02-09 | 2019-10-15 | Albireo Ab | Oral cholestyramine formulation and use thereof |
| US10786529B2 (en) | 2016-02-09 | 2020-09-29 | Albireo Ab | Oral cholestyramine formulation and use thereof |
| JP2020530448A (ja) | 2017-08-09 | 2020-10-22 | アルビレオ・アクチボラグ | コレスチラミン顆粒、経口コレスチラミン製剤、及びそれらの使用 |
| US10793534B2 (en) | 2018-06-05 | 2020-10-06 | Albireo Ab | Benzothia(di)azepine compounds and their use as bile acid modulators |
| ES2942443T3 (es) | 2018-06-05 | 2023-06-01 | Albireo Ab | Compuestos de benzotia(di)azepina y su uso como moduladores de ácidos biliares |
| US11801226B2 (en) | 2018-06-20 | 2023-10-31 | Albireo Ab | Pharmaceutical formulation of odevixibat |
| BR112020024479A2 (pt) | 2018-06-20 | 2021-03-02 | Albireo Ab | hidrato cristalino, modificações cristalinas de odevixibat, solvato misto de odevixibat, uso de modificação cristalina de odevixibat, processo para a preparação de modificação cristalina de odevixibat, e, composição farmacêutica |
| GB201812382D0 (en) | 2018-07-30 | 2018-09-12 | Nzp Uk Ltd | Compounds |
| US10722457B2 (en) | 2018-08-09 | 2020-07-28 | Albireo Ab | Oral cholestyramine formulation and use thereof |
| US11549878B2 (en) | 2018-08-09 | 2023-01-10 | Albireo Ab | In vitro method for determining the adsorbing capacity of an insoluble adsorbant |
| US11007142B2 (en) | 2018-08-09 | 2021-05-18 | Albireo Ab | Oral cholestyramine formulation and use thereof |
| US10941127B2 (en) | 2019-02-06 | 2021-03-09 | Albireo Ab | Benzothiadiazepine compounds and their use as bile acid modulators |
| HUE060905T2 (hu) | 2019-02-06 | 2023-04-28 | Albireo Ab | Benzotiadiazepin vegyületek és azok alkalmazása epesav modulátorként |
| US10975045B2 (en) | 2019-02-06 | 2021-04-13 | Aibireo AB | Benzothiazepine compounds and their use as bile acid modulators |
| US11014898B1 (en) | 2020-12-04 | 2021-05-25 | Albireo Ab | Benzothiazepine compounds and their use as bile acid modulators |
| ES2973549T3 (es) | 2019-12-04 | 2024-06-20 | Albireo Ab | Compuestos de benzoti(di)azepina y su uso como moduladores de los ácidos biliares |
| CN114786772B (zh) | 2019-12-04 | 2024-04-09 | 阿尔比里奥公司 | 苯并硫杂(二)氮杂环庚三烯化合物及其作为胆汁酸调节剂的用途 |
| CA3158181A1 (en) | 2019-12-04 | 2021-06-10 | Albireo Ab | Benzothia(di)azepine compounds and their use as bile acid modulators |
| CA3158184A1 (en) | 2019-12-04 | 2021-08-10 | Albireo Ab | Benzothiadiazepine compounds and their use as bile acid modulators |
| EP4188541B1 (en) | 2020-08-03 | 2024-12-25 | Albireo AB | Benzothia(di)azepine compounds and their use as bile acid modulators |
| JP2023549226A (ja) | 2020-11-12 | 2023-11-22 | アルビレオ エービー | 進行性家族性肝内胆汁うっ滞症（ｐｆｉｃ）を処置するためのオデビキシバット |
| JP2024500309A (ja) | 2020-12-04 | 2024-01-09 | アルビレオ エービー | ベンゾチア（ジ）アゼピン化合物および胆汁酸モジュレータとしてのその使用 |
| TW202313579A (zh) | 2021-06-03 | 2023-04-01 | 瑞典商艾爾比瑞歐公司 | 苯并噻(二)氮呯(benzothia(di)azepine)化合物及其作為膽酸調節劑之用途 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8825526D0 (en) * | 1988-11-01 | 1988-12-07 | Enzymatix Ltd | Diagnosis |
| US5175320A (en) * | 1989-04-17 | 1992-12-29 | Giuliani S.P.A. | Fluorinated bile acid derivatives, processes for the preparation thereof and pharmaceutical compositions containing them |
| US5843929A (en) | 1996-03-22 | 1998-12-01 | Mayo Foundation For Medical Education And Research | Chemoprevention of metachronous adenomatous colorectal polyps |
-
1997
- 1997-05-22 ES ES97925934T patent/ES2306459T3/es not_active Expired - Lifetime
- 1997-05-22 AT AT97925934T patent/ATE394107T1/de not_active IP Right Cessation
- 1997-05-22 WO PCT/EP1997/002632 patent/WO1997044043A1/en not_active Ceased
- 1997-05-22 DE DE69738667T patent/DE69738667D1/de not_active Expired - Lifetime
- 1997-05-22 JP JP09541562A patent/JP2000510858A/ja active Pending
- 1997-05-22 EP EP97925934A patent/EP0906106B1/en not_active Expired - Lifetime
- 1997-05-22 CA CA002253593A patent/CA2253593C/en not_active Expired - Fee Related
- 1997-05-22 PT PT97925934T patent/PT906106E/pt unknown
- 1997-05-22 AU AU30915/97A patent/AU3091597A/en not_active Abandoned
-
2000
- 2000-10-06 US US09/684,585 patent/US6426340B1/en not_active Expired - Fee Related
-
2009
- 2009-11-02 JP JP2009252071A patent/JP2010059175A/ja not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| EP0906106A1 (en) | 1999-04-07 |
| JP2010059175A (ja) | 2010-03-18 |
| AU3091597A (en) | 1997-12-09 |
| CA2253593A1 (en) | 1997-11-27 |
| DE69738667D1 (de) | 2008-06-19 |
| JP2000510858A (ja) | 2000-08-22 |
| PT906106E (pt) | 2008-08-07 |
| ES2306459T3 (es) | 2008-11-01 |
| WO1997044043A1 (en) | 1997-11-27 |
| US6426340B1 (en) | 2002-07-30 |
| EP0906106B1 (en) | 2008-05-07 |
| CA2253593C (en) | 2008-07-08 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE394107T1 (de) | Vorbeugung und behandlung von kolonadenom oder kolonmikroadenom mit 6-fluorursodeoxycholsäure | |
| BG102668A (en) | Application of ppar-alpha and prar-gamma antagonist for the treatment of syndrome x | |
| NO970039D0 (no) | Fremgangsmåte for inhibering av cancer matastaser ved oral administrering av opplöselig modifisert sitruspektin | |
| DE69909818D1 (de) | Pyrazolopyimidinon-derivate zur behandlung von impotenz | |
| IS4972A (is) | Notkun klóbindiefnisins klíókínól við að framleiða lyfjablöndu til að meðhöndla Alzheimers-sjúkdóm | |
| ATE170077T1 (de) | Verfahren zur behandlung von krebs durch kombinationstherapie mit 2'- halomethylidenderivaten und einem s- oder m-phase spezifischen antineoplastischen wirkstoff | |
| AU2740797A (en) | Androstene derivatives | |
| NO964486D0 (no) | Anvendelse av visse metanbisfosfonsyrederivater for å forhindre lösning av protese og protesemigrering | |
| MY119375A (en) | Treatment of tinnitus using neuroprotective agents | |
| BG105664A (en) | Use of apomophines for the treatment of organic erectile dysfunction in males | |
| MY118986A (en) | Use of (alpha)-1-adrenoreceptor antagonists in the prevention and treatment of benign prostatic hyperplasia | |
| DK1124566T3 (da) | Ikke-fermenteret osmotisk laxativ til behandling og forebyggelse af colorectale cancere | |
| TR199701520T1 (xx) | Ac�n�n iyile�tirilmesi i�in analjesik bile�ikleri �reten h�cre soyu. | |
| MY126321A (en) | Use of (alpha)-adrenoreceptor antagonists in the prevention and treatment of cancer. | |
| DE69329760D1 (de) | Behandlung von magen- und darmgeschwüren mit morphogenen | |
| AU3600199A (en) | A pharmaceutical composition containing ezrin mutated on tyrosine 353 | |
| RU96102110A (ru) | Способ профилактики и лечения изъязвлений роговицы | |
| AU6846300A (en) | Use of cyamemazine for cold turkey benzodiazepine treatment | |
| AU4042795A (en) | Treatment of non-small cell lung carcinoma | |
| NO984196L (no) | FremgangsmÕte for behandling av stoffmisbruk | |
| MX9604692A (es) | Derivados de quinoxalina para el tratamiento de tinnitus. | |
| AU5434899A (en) | Cancer treatment | |
| ATE306269T1 (de) | Behandlung der exzessiven aggressivität mit olanzapine | |
| DK1019066T3 (da) | Fremgangsmåder og præparater til forebyggelse og behandling af halsbrand | |
| TR200102262T2 (tr) | Koroner müdahale ile ilgili kardiovasküler olayların önlenmesi veya azaltılması için yöntem. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 0906106 Country of ref document: EP |
|
| REN | Ceased due to non-payment of the annual fee |