ATE387187T1 - Mikrogranulat auf wirkstoffbasis und verfahren zu seiner herstellung - Google Patents
Mikrogranulat auf wirkstoffbasis und verfahren zu seiner herstellungInfo
- Publication number
- ATE387187T1 ATE387187T1 AT01996363T AT01996363T ATE387187T1 AT E387187 T1 ATE387187 T1 AT E387187T1 AT 01996363 T AT01996363 T AT 01996363T AT 01996363 T AT01996363 T AT 01996363T AT E387187 T1 ATE387187 T1 AT E387187T1
- Authority
- AT
- Austria
- Prior art keywords
- production
- active ingredients
- core
- microgranules
- coated
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0014803A FR2816507B1 (fr) | 2000-11-16 | 2000-11-16 | Microgranules a base de principe actif, procede de fabrication et compositons pharmaceutiques integrant lesdits microgranules |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE387187T1 true ATE387187T1 (de) | 2008-03-15 |
Family
ID=8856551
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT01996363T ATE387187T1 (de) | 2000-11-16 | 2001-11-15 | Mikrogranulat auf wirkstoffbasis und verfahren zu seiner herstellung |
Country Status (15)
Country | Link |
---|---|
US (1) | US7829122B2 (de) |
EP (1) | EP1333812B1 (de) |
JP (1) | JP4234427B2 (de) |
CN (1) | CN1222277C (de) |
AT (1) | ATE387187T1 (de) |
AU (2) | AU2307402A (de) |
CA (1) | CA2427899C (de) |
DE (1) | DE60133028T2 (de) |
DK (1) | DK1333812T3 (de) |
ES (1) | ES2300384T3 (de) |
FR (1) | FR2816507B1 (de) |
HK (1) | HK1063017A1 (de) |
MX (1) | MXPA03004300A (de) |
PT (1) | PT1333812E (de) |
WO (1) | WO2002039981A1 (de) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2796840B1 (fr) * | 1999-07-26 | 2003-06-20 | Ethypharm Lab Prod Ethiques | Comprimes faiblement doses et procede de preparation |
EP1279402B1 (de) * | 2001-07-26 | 2006-11-29 | Ethypharm | Umgehüllte Allylamine oder Benzylamine enthaltende Granulate, Verfahren zur Herstellung und in der Mundhöhle dispergierbare Tabletten enthaltend die umgehüllten Granulate |
FR2831820B1 (fr) * | 2001-11-05 | 2004-08-20 | Ethypharm Sa | Comprime orodispersible presentant une grande homogeneite et son procede de preparation |
US6723348B2 (en) * | 2001-11-16 | 2004-04-20 | Ethypharm | Orodispersible tablets containing fexofenadine |
FR2850576B1 (fr) * | 2003-02-05 | 2007-03-23 | Ethypharm Sa | Composition comprenant un melange de principes actifs, et procede de preparation |
WO2005011707A1 (en) * | 2003-07-25 | 2005-02-10 | Warner Chilcott Company, Inc. | A doxycycline metal complex in a solid dosage form |
US8758816B2 (en) | 2004-11-24 | 2014-06-24 | Meda Pharmaceuticals Inc. | Compositions comprising azelastine and methods of use thereof |
US20070020330A1 (en) | 2004-11-24 | 2007-01-25 | Medpointe Healthcare Inc. | Compositions comprising azelastine and methods of use thereof |
PT2522365T (pt) | 2004-11-24 | 2017-02-08 | Meda Pharmaceuticals Inc | Composições que compreendem azelastina e seus métodos de utilização |
CN101128206A (zh) * | 2005-01-21 | 2008-02-20 | 沃纳奇尔科特公司 | 固体剂型形式的四环素类金属络合物 |
CN101912360A (zh) * | 2010-07-13 | 2010-12-15 | 山东达因海洋生物制药股份有限公司 | 布洛芬混悬液及其制备方法 |
US8808736B2 (en) | 2011-02-11 | 2014-08-19 | Zx Pharma, Llc | Enteric coated multiparticulate controlled release peppermint oil composition and related methods |
US8911780B2 (en) | 2011-02-11 | 2014-12-16 | Zx Pharma, Llc | Multiparticulate L-menthol formulations and related methods |
PL2672981T3 (pl) | 2011-02-11 | 2018-09-28 | Zx Pharma, Llc | Wielocząstkowe preparaty l-mentolu i powiązane sposoby |
DE102012007671A1 (de) | 2012-04-16 | 2013-10-17 | Acino Pharma Ag | Pellets mit hohem Wirkstoffgehalt |
FR2999432B1 (fr) | 2012-12-17 | 2014-12-12 | Ethypharm Sa | Comprimes orodispersibles obtenus par compression moulage |
WO2014175852A1 (en) | 2013-04-23 | 2014-10-30 | Zx Pharma, Llc | Enteric coated multiparticulate controlled release peppermint oil composition and related methods |
KR102019645B1 (ko) * | 2019-02-21 | 2019-09-09 | 한국화학연구원 | 염기성오염물질 제거용 비드 및 이의 제조방법 |
CN111184694A (zh) * | 2020-01-19 | 2020-05-22 | 广东青云山药业有限公司 | 一种口腔速溶颗粒的制备方法 |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3558768A (en) * | 1969-12-19 | 1971-01-26 | Sterling Drug Inc | Sustained release pharmaceutical compositions |
IT1115596B (it) | 1978-03-13 | 1986-02-03 | Bayer Italia Spa | Metodo per la preparazione di microgranuli gastoresistenti ed enterosolubili di sostanze farmaceutiche,in particolare di sostanze proteiche e microgranuli preparati con detto metodo |
US4248858A (en) * | 1979-08-09 | 1981-02-03 | American Home Products Corporation | Sustained release pharmaceutical compositions |
IT1180507B (it) * | 1984-06-29 | 1987-09-23 | Roberto Valducci | Procedimento per la preparazione di etofibrato o sostanze di pari o simili caratteristiche, in microgunuli-ritardo e prodotto ottenuto con tale procedimento |
JPS63188621A (ja) * | 1987-01-30 | 1988-08-04 | Taisho Pharmaceut Co Ltd | 矯味経口製剤 |
US5026560A (en) * | 1987-01-29 | 1991-06-25 | Takeda Chemical Industries, Ltd. | Spherical granules having core and their production |
US4853229A (en) * | 1987-10-26 | 1989-08-01 | Alza Corporation | Method for adminstering tiny pills |
US5344657A (en) * | 1988-04-27 | 1994-09-06 | Elf Sanofi | Microbeads of diltiazem, a process for their manufacture and a substained-release pharmaceutical composition containing them |
JP3078859B2 (ja) | 1990-02-23 | 2000-08-21 | 武田薬品工業株式会社 | 安定な放出制御性製剤用コーティング剤 |
SE9003296L (sv) * | 1990-10-16 | 1992-04-17 | Kabi Pharmacia Ab | Foerfarande foer att formulera laekemedel |
WO1995022319A1 (en) | 1994-02-16 | 1995-08-24 | Abbott Laboratories | Process for preparing fine particle pharmaceutical formulations |
US5837292A (en) * | 1996-07-03 | 1998-11-17 | Yamanouchi Europe B.V. | Granulate for the preparation of fast-disintegrating and fast-dissolving compositions containing a high amount of drug |
-
2000
- 2000-11-16 FR FR0014803A patent/FR2816507B1/fr not_active Expired - Lifetime
-
2001
- 2001-11-15 ES ES01996363T patent/ES2300384T3/es not_active Expired - Lifetime
- 2001-11-15 DE DE60133028T patent/DE60133028T2/de not_active Expired - Lifetime
- 2001-11-15 AU AU2307402A patent/AU2307402A/xx active Pending
- 2001-11-15 AT AT01996363T patent/ATE387187T1/de active
- 2001-11-15 US US10/416,848 patent/US7829122B2/en active Active
- 2001-11-15 PT PT01996363T patent/PT1333812E/pt unknown
- 2001-11-15 EP EP01996363A patent/EP1333812B1/de not_active Expired - Lifetime
- 2001-11-15 JP JP2002542356A patent/JP4234427B2/ja not_active Expired - Fee Related
- 2001-11-15 WO PCT/FR2001/003584 patent/WO2002039981A1/fr active IP Right Grant
- 2001-11-15 AU AU2002223074A patent/AU2002223074B2/en not_active Ceased
- 2001-11-15 MX MXPA03004300A patent/MXPA03004300A/es active IP Right Grant
- 2001-11-15 CA CA2427899A patent/CA2427899C/fr not_active Expired - Lifetime
- 2001-11-15 CN CN01820962.9A patent/CN1222277C/zh not_active Expired - Lifetime
- 2001-11-15 DK DK01996363T patent/DK1333812T3/da active
-
2004
- 2004-08-06 HK HK04105869D patent/HK1063017A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
US7829122B2 (en) | 2010-11-09 |
DE60133028D1 (de) | 2008-04-10 |
AU2307402A (en) | 2002-05-27 |
MXPA03004300A (es) | 2004-09-10 |
CN1481235A (zh) | 2004-03-10 |
EP1333812B1 (de) | 2008-02-27 |
AU2002223074B2 (en) | 2005-03-10 |
CN1222277C (zh) | 2005-10-12 |
JP4234427B2 (ja) | 2009-03-04 |
EP1333812A1 (de) | 2003-08-13 |
WO2002039981A1 (fr) | 2002-05-23 |
FR2816507A1 (fr) | 2002-05-17 |
JP2004517064A (ja) | 2004-06-10 |
FR2816507B1 (fr) | 2003-02-28 |
US20040101568A1 (en) | 2004-05-27 |
ES2300384T3 (es) | 2008-06-16 |
HK1063017A1 (en) | 2004-12-10 |
CA2427899C (fr) | 2011-05-10 |
DK1333812T3 (da) | 2008-03-31 |
DE60133028T2 (de) | 2009-03-12 |
CA2427899A1 (fr) | 2002-05-23 |
PT1333812E (pt) | 2008-03-17 |
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Legal Events
Date | Code | Title | Description |
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UEP | Publication of translation of european patent specification |
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