ATE384117T1 - Verwendung einer miniaturvorrichtung zur trennung und isolierung biologischer objekte und trennungsverfahren - Google Patents

Verwendung einer miniaturvorrichtung zur trennung und isolierung biologischer objekte und trennungsverfahren

Info

Publication number
ATE384117T1
ATE384117T1 AT02735507T AT02735507T ATE384117T1 AT E384117 T1 ATE384117 T1 AT E384117T1 AT 02735507 T AT02735507 T AT 02735507T AT 02735507 T AT02735507 T AT 02735507T AT E384117 T1 ATE384117 T1 AT E384117T1
Authority
AT
Austria
Prior art keywords
separation
isolation
biological objects
miniature device
separation method
Prior art date
Application number
AT02735507T
Other languages
English (en)
Inventor
Patrice Caillat
Alexandra Fuchs
Frederic Revol-Cavalier
Daniel Dupret
Fabrice Lefevre
Original Assignee
Commissariat Energie Atomique
Proteus
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Commissariat Energie Atomique, Proteus filed Critical Commissariat Energie Atomique
Application granted granted Critical
Publication of ATE384117T1 publication Critical patent/ATE384117T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • G01N33/5438—Electrodes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502753—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by bulk separation arrangements on lab-on-a-chip devices, e.g. for filtration or centrifugation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C5/00—Separating dispersed particles from liquids by electrostatic effect
    • B03C5/02—Separators
    • B03C5/022—Non-uniform field separators
    • B03C5/026—Non-uniform field separators using open-gradient differential dielectric separation, i.e. using electrodes of special shapes for non-uniform field creation, e.g. Fluid Integrated Circuit [FIC]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M47/00—Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
    • C12M47/04—Cell isolation or sorting
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0819—Microarrays; Biochips
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0887—Laminated structure
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0415—Moving fluids with specific forces or mechanical means specific forces electrical forces, e.g. electrokinetic
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5025—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures for parallel transport of multiple samples
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C2201/00—Details of magnetic or electrostatic separation
    • B03C2201/26—Details of magnetic or electrostatic separation for use in medical applications

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Urology & Nephrology (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Sustainable Development (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Food Science & Technology (AREA)
  • Dispersion Chemistry (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microelectronics & Electronic Packaging (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Electrostatic Separation (AREA)
  • Processing And Handling Of Plastics And Other Materials For Molding In General (AREA)
  • Sampling And Sample Adjustment (AREA)
AT02735507T 2001-04-27 2002-04-26 Verwendung einer miniaturvorrichtung zur trennung und isolierung biologischer objekte und trennungsverfahren ATE384117T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0105706A FR2824143B1 (fr) 2001-04-27 2001-04-27 Utilisations d'un dispositif miniature de separation et d'isolement d'objets biologiques et procedes mis en oeuvre

Publications (1)

Publication Number Publication Date
ATE384117T1 true ATE384117T1 (de) 2008-02-15

Family

ID=8862776

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02735507T ATE384117T1 (de) 2001-04-27 2002-04-26 Verwendung einer miniaturvorrichtung zur trennung und isolierung biologischer objekte und trennungsverfahren

Country Status (7)

Country Link
US (1) US20040175708A1 (de)
EP (1) EP1390467B1 (de)
JP (1) JP2004535177A (de)
AT (1) ATE384117T1 (de)
DE (1) DE60224663D1 (de)
FR (1) FR2824143B1 (de)
WO (1) WO2002088300A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2847581B1 (fr) * 2002-11-21 2007-03-23 Commissariat Energie Atomique Procede de fixation d'une proteine sur un polymere a base de pyrrole et son utilisation pour la fabrication d'un capteur
FR2855269B1 (fr) * 2003-05-21 2007-06-08 Commissariat Energie Atomique Dispositif et procedes d'accrochage/decrochage d'une cible ou d'un objet present dans un echantillon
KR100597870B1 (ko) * 2004-04-01 2006-07-06 한국과학기술원 고속 스크리닝 또는 고속 분석을 위한 미소 유체 칩
KR101138472B1 (ko) 2009-12-15 2012-04-25 가천대학교 산학협력단 바이오 칩의 미세환경 내에서 세포를 공배양하는 방법
US10571475B2 (en) 2010-12-03 2020-02-25 Cellply S.R.L. Rapid screening of monoclonal antibodies
CA3027317A1 (en) 2016-06-14 2017-12-21 Cellply S.R.L. Screening kit and method
DE102018211001A1 (de) * 2018-07-04 2020-01-09 Robert Bosch Gmbh Vorrichtung zum dielektrophoretischen Einfang von Teilchen

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4400955C2 (de) * 1993-12-23 1999-04-01 Fraunhofer Ges Forschung Adhäsionssteuerbare Oberflächenstruktur
FR2781886B1 (fr) * 1998-07-31 2001-02-16 Commissariat Energie Atomique Micro-systeme a multiple points d'analyse chimique ou biologique
DE19841125A1 (de) * 1998-09-09 2000-03-16 Inst Oberflaechenmodifizierung Verfahren und Anordnung zur Beweglichkeitseinschränkung von lebenden Zellen
FR2787582B1 (fr) * 1998-12-16 2001-01-12 Commissariat Energie Atomique Procede de fabrication d'une biopuce et biopuce

Also Published As

Publication number Publication date
FR2824143A1 (fr) 2002-10-31
EP1390467B1 (de) 2008-01-16
US20040175708A1 (en) 2004-09-09
FR2824143B1 (fr) 2003-06-27
WO2002088300A1 (fr) 2002-11-07
DE60224663D1 (de) 2008-03-06
EP1390467A1 (de) 2004-02-25
JP2004535177A (ja) 2004-11-25

Similar Documents

Publication Publication Date Title
ATE540114T1 (de) Verfahren und zusammensetzungen zur schnellen isolierung kleiner rna-moleküle
DE60219074D1 (de) Mehrstufige vorrichtung und verfahren zur trennung von fluiden
ATE449186T1 (de) Zusammensetzungen und verfahren zur selektiven nukleinsäureisolierung
ATE350488T1 (de) Verfahren und testsysteme zur identifizierung von elite event gat-zm1 in biologischen proben
WO2005012574A3 (en) Biological bar-code
DE602004010240D1 (de) Tupfer zur aufnahme von biologischen proben
AU2002218166A1 (en) Collections of repeat proteins comprising repeat modules
ATE419388T1 (de) Nukleinsäureanreicherung
ATE469219T1 (de) Zusammensetzungen, methoden und reagentien zur nukleinsäureisolierung mittels oberflächenaktiven substanzen und proteasen
CA2545989A1 (en) Method and device for purifying nucleic acids
AU6380001A (en) Porous ferro- or ferrimagnetic glass particles for isolating molecules
ATE465811T1 (de) Methode zur trennung von komponenten eines gemisches
DE50307634D1 (de) Vorrichtung zur Herstellung von Klebebindungen von Blocks und Broschüren insbesondere für Kleinauflagen
DE60232618D1 (de) Mikrofluidische Vorrichtung, Verfahren zur Herstellung und Verwendung desselben
DE60125710D1 (de) Manipulationssichere Methode zur modularen Multiplikation
DE60223704D1 (de) Vorrichtung zur extraktion von nukleinsäuren
AU2002223841A1 (en) Method of separating extra-chromosomal dna from other cellular components
ATE437486T1 (de) Verfahren zur konfiguration von physischen kanälen
DE60325381D1 (de) Proteine die cross-beta-struktur enthaltendes amyloid binden, sowie verfahren zur modulation der cross-beta-struktur, ihrer bildung und der damit zusammenhängenden toxizität
DK1523243T3 (da) Mælkeproteinisolat og metode til fremstilling af samme
DE60323579D1 (de) Methode zur Separierung von Nukleinsäuren und dafür verwendbare Reagenz
ATE384117T1 (de) Verwendung einer miniaturvorrichtung zur trennung und isolierung biologischer objekte und trennungsverfahren
DE50204289D1 (de) Vorrichtung und verfahren zur selektion von selbstbeweglichen biologischen spezies, insbesondere von samenzellen
DE60234250D1 (de) Vorrichtung zur Zell- bzw. Gewebezüchtung
DE60124836D1 (de) Element, Vorrichtung, Verfahren und Bausatz zur Trennung von Partikeln

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties