ATE384045T1 - Inhibitoren von cytosolischen phospholipase a2 - Google Patents
Inhibitoren von cytosolischen phospholipase a2Info
- Publication number
- ATE384045T1 ATE384045T1 AT02786829T AT02786829T ATE384045T1 AT E384045 T1 ATE384045 T1 AT E384045T1 AT 02786829 T AT02786829 T AT 02786829T AT 02786829 T AT02786829 T AT 02786829T AT E384045 T1 ATE384045 T1 AT E384045T1
- Authority
- AT
- Austria
- Prior art keywords
- inhibitors
- cytosolic phospholipase
- cytosolic
- phospholipase
- Prior art date
Links
- 102100037611 Lysophospholipase Human genes 0.000 title 1
- 108020002496 Lysophospholipase Proteins 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
- C07D209/16—Tryptamines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/08—Bridged systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Pulmonology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Pain & Pain Management (AREA)
- Immunology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US33459101P | 2001-12-03 | 2001-12-03 | |
| US33458801P | 2001-12-03 | 2001-12-03 | |
| US33460501P | 2001-12-03 | 2001-12-03 | |
| US41966402P | 2002-10-18 | 2002-10-18 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE384045T1 true ATE384045T1 (de) | 2008-02-15 |
Family
ID=27502498
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02786829T ATE384045T1 (de) | 2001-12-03 | 2002-12-02 | Inhibitoren von cytosolischen phospholipase a2 |
Country Status (24)
| Country | Link |
|---|---|
| EP (1) | EP1451154B1 (enExample) |
| JP (1) | JP4657605B2 (enExample) |
| KR (1) | KR100973665B1 (enExample) |
| CN (1) | CN100503566C (enExample) |
| AR (1) | AR037684A1 (enExample) |
| AT (1) | ATE384045T1 (enExample) |
| AU (1) | AU2002351182B2 (enExample) |
| BR (1) | BR0214672A (enExample) |
| CA (1) | CA2469138C (enExample) |
| CO (1) | CO5580763A2 (enExample) |
| CY (1) | CY1107383T1 (enExample) |
| DE (1) | DE60224707T2 (enExample) |
| DK (2) | DK1892239T3 (enExample) |
| EC (1) | ECSP045131A (enExample) |
| ES (2) | ES2300490T3 (enExample) |
| HU (1) | HUP0402577A3 (enExample) |
| IL (2) | IL162052A0 (enExample) |
| IN (1) | IN2005KO00312A (enExample) |
| NO (1) | NO327256B1 (enExample) |
| NZ (1) | NZ533269A (enExample) |
| PL (1) | PL370445A1 (enExample) |
| PT (1) | PT1451154E (enExample) |
| TW (1) | TWI334778B (enExample) |
| WO (1) | WO2003048122A2 (enExample) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7713964B2 (en) | 2001-12-03 | 2010-05-11 | Wyeth Llc | Methods for treating asthmatic conditions |
| US7605156B2 (en) | 2001-12-03 | 2009-10-20 | Wyeth | Methods for the use of inhibitors of cytosolic phospholipase A2 |
| TW200510305A (en) * | 2003-07-25 | 2005-03-16 | Wyeth Corp | Process for the preparation of CPLA2 inhibitors |
| PL1685104T3 (pl) | 2003-11-17 | 2008-03-31 | Wyeth Corp | Sposoby wytwarzania N-podstawionych ftalimidów |
| HN2004000536A (es) * | 2003-12-16 | 2009-02-18 | Wyeth Corp | Un procediemiento de sintesis para la alquilacion reductiva de la posicon c-3 de indoles |
| AR048239A1 (es) | 2004-02-25 | 2006-04-12 | Wyeth Corp | Procesos para la preparacion de haluros de aril- y heteroaril-alquilsulfonilo e intermediarios de sintesis de los mismos |
| US20050244367A1 (en) * | 2004-05-03 | 2005-11-03 | Ilypsa, Inc. | Phospholipase inhibitors localized in the gastrointestinal lumen |
| AR053410A1 (es) * | 2004-08-19 | 2007-05-09 | Wyeth Corp | Proceso para la sintesis de indoles n-alquilados c-2, c-3 sustituidos. compuestos intermediarios |
| ATE473735T1 (de) | 2005-04-13 | 2010-07-15 | Astion Dev As | Beta-2 adrenoceptor agonisten zur behandlung von bindegewebserkrankungen der haut |
| GT200600228A (es) | 2005-05-27 | 2006-12-26 | Inhibidores de la fosfolipasa a2 citosolica | |
| TW200728262A (en) * | 2005-07-21 | 2007-08-01 | Wyeth Corp | Process for the synthesis of sulfonyl halides and sulfonamides from sulfonic acid salts |
| MX2008005666A (es) | 2005-11-03 | 2009-03-02 | Ilypsa Inc | Compuestos multivalentes de indol y uso de los mismos como inhibidores de fosfolipasa-a2. |
| FR2899471A1 (fr) * | 2006-04-06 | 2007-10-12 | Pasteur Institut | Utilisation d'au moins un inhibiteur de la phospholipase a2 cytosolique comme medicament pour le traitement des maladies respiratoires |
| WO2007140317A2 (en) * | 2006-05-26 | 2007-12-06 | Wyeth | Use of inhibitors of cytosolic ph0sph0lipase a2 in the treatment of thrombosis |
| WO2008055146A2 (en) * | 2006-10-31 | 2008-05-08 | Wyeth | Formulations of phospholipase enzyme inhibitors |
| BRPI0718066A2 (pt) * | 2006-10-31 | 2013-11-05 | Wyeth Corp | Composição farmacêutica; forma de dosagem farmacêutica; processo para preparar uma composição farmacêutica;e produto. |
| WO2008120818A1 (ja) * | 2007-03-29 | 2008-10-09 | Asubio Pharma Co., Ltd. | ｃＰＬＡ２阻害活性を有するインドール誘導体およびその用途並びに製造方法 |
| KR101269393B1 (ko) | 2008-04-28 | 2013-05-29 | 아사히 가세이 파마 가부시키가이샤 | 페닐프로피온산 유도체 및 이의 용도 |
| CA2777782C (en) * | 2009-10-15 | 2016-06-28 | Children's Medical Center Corporation | Sepiapterin reductase inhibitors for the treatment of pain |
| EP2614144B1 (en) | 2010-09-08 | 2015-07-22 | Twincore Zentrum für Experimentelle und Klinische Infektionsforschung GmbH | Use of inhibitors of phospholipase a2 for the treatment or prevention of flavivirus infection |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2079374C (en) * | 1991-09-30 | 2003-08-05 | Merck Frosst Canada Incorporated | (bicyclic-azaarylmethoxy)indoles as inhibitors of leukotriene biosynthesis |
| US5994398A (en) * | 1996-12-11 | 1999-11-30 | Elan Pharmaceuticals, Inc. | Arylsulfonamides as phospholipase A2 inhibitors |
| HRP20000552A2 (en) * | 1998-02-25 | 2001-04-30 | Genetics Inst | Inhibitors of phospholipase enzymes |
| AU765427B2 (en) * | 1998-02-25 | 2003-09-18 | Genetics Institute, Llc | Inhibitors of phospholipase enzymes |
-
2002
- 2002-12-02 DK DK07023208.7T patent/DK1892239T3/da active
- 2002-12-02 KR KR1020047008482A patent/KR100973665B1/ko not_active Expired - Lifetime
- 2002-12-02 NZ NZ533269A patent/NZ533269A/xx not_active IP Right Cessation
- 2002-12-02 TW TW091134928A patent/TWI334778B/zh not_active IP Right Cessation
- 2002-12-02 AT AT02786829T patent/ATE384045T1/de active
- 2002-12-02 IL IL16205202A patent/IL162052A0/xx unknown
- 2002-12-02 DK DK02786829T patent/DK1451154T3/da active
- 2002-12-02 ES ES02786829T patent/ES2300490T3/es not_active Expired - Lifetime
- 2002-12-02 CN CNB028276116A patent/CN100503566C/zh not_active Expired - Lifetime
- 2002-12-02 PL PL02370445A patent/PL370445A1/xx not_active Application Discontinuation
- 2002-12-02 AR ARP020104643A patent/AR037684A1/es unknown
- 2002-12-02 HU HU0402577A patent/HUP0402577A3/hu unknown
- 2002-12-02 JP JP2003549314A patent/JP4657605B2/ja not_active Expired - Lifetime
- 2002-12-02 WO PCT/US2002/038311 patent/WO2003048122A2/en not_active Ceased
- 2002-12-02 PT PT02786829T patent/PT1451154E/pt unknown
- 2002-12-02 EP EP02786829A patent/EP1451154B1/en not_active Expired - Lifetime
- 2002-12-02 DE DE60224707T patent/DE60224707T2/de not_active Expired - Lifetime
- 2002-12-02 AU AU2002351182A patent/AU2002351182B2/en not_active Expired
- 2002-12-02 ES ES07023208T patent/ES2401454T3/es not_active Expired - Lifetime
- 2002-12-02 BR BR0214672-0A patent/BR0214672A/pt not_active Application Discontinuation
- 2002-12-02 CA CA2469138A patent/CA2469138C/en not_active Expired - Lifetime
-
2004
- 2004-05-19 IL IL162052A patent/IL162052A/en active IP Right Grant
- 2004-05-31 CO CO04050432A patent/CO5580763A2/es not_active Application Discontinuation
- 2004-06-03 EC EC2004005131A patent/ECSP045131A/es unknown
- 2004-06-25 NO NO20042679A patent/NO327256B1/no not_active IP Right Cessation
-
2005
- 2005-04-12 IN IN312KO2005 patent/IN2005KO00312A/en unknown
-
2008
- 2008-03-31 CY CY20081100371T patent/CY1107383T1/el unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE370938T1 (de) | Pro-pharmakon von cox-2-inhibitoren | |
| DE60224707D1 (de) | Inhibitoren von cytosolischen phospholipase a2 | |
| DE60232994D1 (de) | Inhibitoren von mitotischem kinesin | |
| ID27280A (id) | Inhibitor-inhibitor dari enzim-enzim fosfolipase | |
| CY2015028I2 (el) | Ενας αναστολεας ν-ακυλοσφιγγοσινο γλυκοζυλοτρανσφερασης | |
| DE60234125D1 (de) | E inhibitoren | |
| NO20004217D0 (no) | Inhibitorer av fosfolipase A2 | |
| NO20034044D0 (no) | Metallproteinase-inhibitorer | |
| EE200300439A (et) | Metalloproteinaasi inhibiitorid | |
| PT1370553E (pt) | Inibidores de rhoquinase | |
| EP1444209A4 (en) | INHIBITORS OF MITOTIC KINESINS | |
| EP1465896A4 (en) | INHIBITORS OF MITOTIC KINESINE | |
| ID26250A (id) | Inhibitor-inhibitor dari enzim-enzim fosfolipase | |
| EE200300450A (et) | Metalloproteinaasi inhibiitorid | |
| EP1474093A4 (en) | Granzyme B INHIBITORS | |
| DK1458447T3 (da) | Kombination af cytokrom-p450-beroende proteasinhibitorer | |
| EP1463521A4 (en) | INHIBITOR OF GP41 | |
| DE50203046D1 (de) | Verwendung von Esterquats | |
| ATE331956T1 (de) | Nachweis von entzündungen | |
| DE60124397D1 (de) | Inhibitoren von serinproteasen | |
| DE50203105D1 (de) | Lagerung von entnahmeelementen | |
| SI1451154T1 (sl) | Zaviralci citosolne fosfolipaze a2 | |
| ITBA20010029V0 (it) | Gioiello di puglia | |
| DE60224373D1 (de) | Erfassung von objekten | |
| SE0100694D0 (sv) | DHFR inhibitors |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 1451154 Country of ref document: EP |