ATE383370T1 - Verbindungen die p-selectin binden - Google Patents
Verbindungen die p-selectin bindenInfo
- Publication number
- ATE383370T1 ATE383370T1 AT03792179T AT03792179T ATE383370T1 AT E383370 T1 ATE383370 T1 AT E383370T1 AT 03792179 T AT03792179 T AT 03792179T AT 03792179 T AT03792179 T AT 03792179T AT E383370 T1 ATE383370 T1 AT E383370T1
- Authority
- AT
- Austria
- Prior art keywords
- compounds
- selectin
- binding
- bind
- derivatives
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 6
- 238000000034 method Methods 0.000 abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 2
- 101000622137 Homo sapiens P-selectin Proteins 0.000 abstract 1
- 108010035766 P-Selectin Proteins 0.000 abstract 1
- 102000008212 P-Selectin Human genes 0.000 abstract 1
- 238000002405 diagnostic procedure Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1002—Tetrapeptides with the first amino acid being neutral
- C07K5/1016—Tetrapeptides with the first amino acid being neutral and aromatic or cycloaliphatic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Urology & Nephrology (AREA)
- Rheumatology (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pain & Pain Management (AREA)
- Vascular Medicine (AREA)
- Physical Education & Sports Medicine (AREA)
- Pulmonology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Transplantation (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Diabetes (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP02078308 | 2002-08-09 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE383370T1 true ATE383370T1 (de) | 2008-01-15 |
Family
ID=31896910
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT03792179T ATE383370T1 (de) | 2002-08-09 | 2003-07-04 | Verbindungen die p-selectin binden |
Country Status (11)
| Country | Link |
|---|---|
| US (3) | US20060217294A1 (https=) |
| EP (1) | EP1527086B1 (https=) |
| JP (2) | JP4563806B2 (https=) |
| AT (1) | ATE383370T1 (https=) |
| AU (1) | AU2003250899A1 (https=) |
| BR (1) | BR0313019A (https=) |
| CA (1) | CA2493471C (https=) |
| DE (1) | DE60318585T2 (https=) |
| ES (1) | ES2299749T3 (https=) |
| MX (1) | MXPA05001599A (https=) |
| WO (1) | WO2004018502A1 (https=) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2004018502A1 (en) * | 2002-08-09 | 2004-03-04 | Yamanouchi Europe B.V. | Compounds binding to p-selectin |
| JP4603888B2 (ja) | 2002-10-11 | 2010-12-22 | アステラス ファルマ ユーロープ ベスローテン フェンノートシャップ | Ｐ−セレクチンに対する親和性を有しグルコースをベースとする化合物 |
| EP1577289A1 (en) * | 2004-03-18 | 2005-09-21 | Revotar Biopharmaceuticals AG | Non-glycosylated/-glycosidic/-peptidic small molecule selectin inhibitors for the treament of inflammatory disorders |
| EP1764095A1 (en) | 2005-09-20 | 2007-03-21 | Revotar Biopharmaceuticals AG | Novel nitrocatechol derivatives having selectin ligand activity |
| EP1764093A1 (en) | 2005-09-20 | 2007-03-21 | Revotar Biopharmaceuticals AG | Novel aromatic compounds and their use in medical applications |
| EP1764096A1 (en) | 2005-09-20 | 2007-03-21 | Revotar Biopharmaceuticals AG | Novel phloroglucinol derivatives having selectin ligand activity |
| MX2009002492A (es) * | 2006-09-08 | 2009-08-28 | Bayer Schering Pharma Ag | Agentes que comprenden compuestos marcados con 18f y metodos relacionados. |
| US10450343B2 (en) | 2013-03-21 | 2019-10-22 | Sanofi-Aventis Deutschland Gmbh | Synthesis of cyclic imide containing peptide products |
| CA2907454C (en) | 2013-03-21 | 2021-05-04 | Sanofi-Aventis Deutschland Gmbh | Synthesis of hydantoin containing peptide products |
| AU2021208650A1 (en) * | 2020-01-16 | 2022-08-11 | Case Western Reserve University | Neutrophil elastase binding peptides and compositions thereof |
| CN115039782A (zh) * | 2022-07-20 | 2022-09-13 | 中国农业科学院植物保护研究所 | 一种化合物在大豆孢囊线虫几丁质酶抑制剂中的应用 |
| WO2025168211A1 (en) | 2023-02-10 | 2025-08-14 | Novo Nordisk A/S | P-selectin peptide ligands |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1994005314A1 (en) * | 1992-09-08 | 1994-03-17 | Centocor, Inc. | Peptide inhibitors of leukocyte adhesion |
| AU2958195A (en) * | 1994-06-29 | 1996-01-25 | Texas Biotechnology Corporation | Process to inhibit binding of the integrin alpha 4 beta 1 to vcam-1 or fibronectin |
| WO2000027420A1 (en) * | 1998-11-06 | 2000-05-18 | The Wistar Institute Of Anatomy And Biology | Compositions and methods for treatment of cancer |
| EP1288222A1 (en) * | 2001-09-03 | 2003-03-05 | Yamanouchi Europe B.V. | Peptidic compounds selectively binding to P-selectin |
| WO2004018502A1 (en) * | 2002-08-09 | 2004-03-04 | Yamanouchi Europe B.V. | Compounds binding to p-selectin |
-
2003
- 2003-07-04 WO PCT/EP2003/007260 patent/WO2004018502A1/en not_active Ceased
- 2003-07-04 DE DE60318585T patent/DE60318585T2/de not_active Expired - Lifetime
- 2003-07-04 US US10/524,172 patent/US20060217294A1/en not_active Abandoned
- 2003-07-04 JP JP2004530000A patent/JP4563806B2/ja not_active Expired - Fee Related
- 2003-07-04 CA CA2493471A patent/CA2493471C/en not_active Expired - Fee Related
- 2003-07-04 AU AU2003250899A patent/AU2003250899A1/en not_active Abandoned
- 2003-07-04 ES ES03792179T patent/ES2299749T3/es not_active Expired - Lifetime
- 2003-07-04 EP EP03792179A patent/EP1527086B1/en not_active Expired - Lifetime
- 2003-07-04 BR BR0313019-3A patent/BR0313019A/pt not_active Application Discontinuation
- 2003-07-04 MX MXPA05001599A patent/MXPA05001599A/es unknown
- 2003-07-04 AT AT03792179T patent/ATE383370T1/de not_active IP Right Cessation
-
2008
- 2008-06-25 US US12/146,302 patent/US20090062186A1/en not_active Abandoned
-
2010
- 2010-03-16 US US12/725,199 patent/US20100323969A1/en not_active Abandoned
- 2010-04-21 JP JP2010098138A patent/JP2010209088A/ja not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| MXPA05001599A (es) | 2005-08-19 |
| BR0313019A (pt) | 2005-07-12 |
| WO2004018502A1 (en) | 2004-03-04 |
| WO2004018502A8 (en) | 2005-05-12 |
| US20090062186A1 (en) | 2009-03-05 |
| EP1527086B1 (en) | 2008-01-09 |
| DE60318585D1 (de) | 2008-02-21 |
| JP2006513141A (ja) | 2006-04-20 |
| JP2010209088A (ja) | 2010-09-24 |
| US20100323969A1 (en) | 2010-12-23 |
| DE60318585T2 (de) | 2009-01-08 |
| AU2003250899A1 (en) | 2004-03-11 |
| CA2493471A1 (en) | 2004-03-04 |
| US20060217294A1 (en) | 2006-09-28 |
| JP4563806B2 (ja) | 2010-10-13 |
| EP1527086A1 (en) | 2005-05-04 |
| CA2493471C (en) | 2013-02-12 |
| ES2299749T3 (es) | 2008-06-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |