ATE382039T1 - Benzimidazolone und ihre verwendung als cytokininhibitoren - Google Patents
Benzimidazolone und ihre verwendung als cytokininhibitorenInfo
- Publication number
- ATE382039T1 ATE382039T1 AT03795649T AT03795649T ATE382039T1 AT E382039 T1 ATE382039 T1 AT E382039T1 AT 03795649 T AT03795649 T AT 03795649T AT 03795649 T AT03795649 T AT 03795649T AT E382039 T1 ATE382039 T1 AT E382039T1
- Authority
- AT
- Austria
- Prior art keywords
- sub
- compounds
- benzimidazolones
- disclosed
- processes
- Prior art date
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- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
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- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
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- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D235/26—Oxygen atoms
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- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
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- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
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- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
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Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US41042002P | 2002-09-13 | 2002-09-13 |
Publications (1)
Publication Number | Publication Date |
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ATE382039T1 true ATE382039T1 (de) | 2008-01-15 |
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ID=31994134
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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AT03795649T ATE382039T1 (de) | 2002-09-13 | 2003-09-04 | Benzimidazolone und ihre verwendung als cytokininhibitoren |
Country Status (9)
Country | Link |
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US (1) | US7115644B2 (de) |
EP (1) | EP1539708B1 (de) |
JP (1) | JP4551765B2 (de) |
AT (1) | ATE382039T1 (de) |
AU (1) | AU2003265924A1 (de) |
CA (1) | CA2498754C (de) |
DE (1) | DE60318320T2 (de) |
ES (1) | ES2297265T3 (de) |
WO (1) | WO2004024699A1 (de) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
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CN102060806A (zh) * | 2003-09-11 | 2011-05-18 | iTherX药品公司 | 细胞因子抑制剂 |
WO2007015877A2 (en) * | 2005-07-20 | 2007-02-08 | Kalypsys, Inc. | Inhibitors of p38 kinase and methods of treating inflammatory disorders |
WO2011021678A1 (ja) * | 2009-08-21 | 2011-02-24 | 武田薬品工業株式会社 | 縮合複素環化合物 |
CN104428293B (zh) * | 2012-06-11 | 2018-06-08 | Ucb生物制药私人有限公司 | 调节TNFα的苯并咪唑类 |
US8901304B1 (en) | 2013-11-05 | 2014-12-02 | King Fahd University Of Petroleum And Minerals | Benzo[D]imidazole derivatives of piperidine and piperazine |
US20190060286A1 (en) | 2016-02-29 | 2019-02-28 | University Of Florida Research Foundation, Incorpo | Chemotherapeutic Methods |
CN109563051B (zh) * | 2016-08-22 | 2024-06-11 | 南京明德新药研发有限公司 | 作为pde4抑制剂的并环类化合物 |
US10342786B2 (en) | 2017-10-05 | 2019-07-09 | Fulcrum Therapeutics, Inc. | P38 kinase inhibitors reduce DUX4 and downstream gene expression for the treatment of FSHD |
PT3691620T (pt) | 2017-10-05 | 2022-10-06 | Fulcrum Therapeutics Inc | Os inibidores da quinase p38 reduzem a expressão de dux4 e genes a jusante para o tratamento de fshd |
GB201820165D0 (en) | 2018-12-11 | 2019-01-23 | Ucb Biopharma Sprl | Therapeutic agents |
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TW203049B (de) * | 1990-04-13 | 1993-04-01 | Yamanouchi Pharma Co Ltd | |
US5281714A (en) | 1990-08-16 | 1994-01-25 | American Home Products Corporation | N,N',N'-trisubstituted-5-bisaminomethylene-1,3-dioxane-4,6-dione inhibitors of acyl-CoA: cholesterol-acyl transferase |
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TW284688B (de) | 1991-11-20 | 1996-09-01 | Takeda Pharm Industry Co Ltd | |
DE4140540A1 (de) | 1991-12-09 | 1993-06-17 | Bayer Ag | Neue azaheterocyclylmethyl-chromane |
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AU675484B2 (en) | 1993-03-24 | 1997-02-06 | Neurosearch A/S | Benzimidazole compounds, their use and preparation |
WO1998032439A1 (en) * | 1997-01-23 | 1998-07-30 | Smithkline Beecham Corporation | Il-8 receptor antagonists |
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-
2003
- 2003-09-03 US US10/654,452 patent/US7115644B2/en not_active Expired - Lifetime
- 2003-09-04 ES ES03795649T patent/ES2297265T3/es not_active Expired - Lifetime
- 2003-09-04 EP EP03795649A patent/EP1539708B1/de not_active Expired - Lifetime
- 2003-09-04 DE DE60318320T patent/DE60318320T2/de not_active Expired - Lifetime
- 2003-09-04 WO PCT/US2003/027692 patent/WO2004024699A1/en active IP Right Grant
- 2003-09-04 JP JP2004536098A patent/JP4551765B2/ja not_active Expired - Lifetime
- 2003-09-04 AT AT03795649T patent/ATE382039T1/de active
- 2003-09-04 AU AU2003265924A patent/AU2003265924A1/en not_active Abandoned
- 2003-09-04 CA CA2498754A patent/CA2498754C/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
CA2498754C (en) | 2012-03-06 |
CA2498754A1 (en) | 2004-03-25 |
JP4551765B2 (ja) | 2010-09-29 |
US20040192748A1 (en) | 2004-09-30 |
EP1539708A1 (de) | 2005-06-15 |
WO2004024699A1 (en) | 2004-03-25 |
US7115644B2 (en) | 2006-10-03 |
DE60318320D1 (de) | 2008-02-07 |
ES2297265T3 (es) | 2008-05-01 |
DE60318320T2 (de) | 2008-12-11 |
AU2003265924A1 (en) | 2004-04-30 |
JP2006503033A (ja) | 2006-01-26 |
EP1539708B1 (de) | 2007-12-26 |
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