ATE380553T1 - Aminpolymere zur behandlung von gicht und zur senkung des harnsäuregehaltes - Google Patents
Aminpolymere zur behandlung von gicht und zur senkung des harnsäuregehaltesInfo
- Publication number
- ATE380553T1 ATE380553T1 AT02726732T AT02726732T ATE380553T1 AT E380553 T1 ATE380553 T1 AT E380553T1 AT 02726732 T AT02726732 T AT 02726732T AT 02726732 T AT02726732 T AT 02726732T AT E380553 T1 ATE380553 T1 AT E380553T1
- Authority
- AT
- Austria
- Prior art keywords
- uric acid
- polymer
- patient
- treating gout
- acid content
- Prior art date
Links
- 229920000642 polymer Polymers 0.000 title abstract 7
- LEHOTFFKMJEONL-UHFFFAOYSA-N Uric Acid Chemical compound N1C(=O)NC(=O)C2=C1NC(=O)N2 LEHOTFFKMJEONL-UHFFFAOYSA-N 0.000 title abstract 4
- TVWHNULVHGKJHS-UHFFFAOYSA-N Uric acid Natural products N1C(=O)NC(=O)C2NC(=O)NC21 TVWHNULVHGKJHS-UHFFFAOYSA-N 0.000 title abstract 4
- 229940116269 uric acid Drugs 0.000 title abstract 4
- 150000001412 amines Chemical class 0.000 title abstract 3
- 210000002966 serum Anatomy 0.000 abstract 2
- VTAKZNRDSPNOAU-UHFFFAOYSA-M 2-(chloromethyl)oxirane;hydron;prop-2-en-1-amine;n-prop-2-enyldecan-1-amine;trimethyl-[6-(prop-2-enylamino)hexyl]azanium;dichloride Chemical compound Cl.[Cl-].NCC=C.ClCC1CO1.CCCCCCCCCCNCC=C.C[N+](C)(C)CCCCCCNCC=C VTAKZNRDSPNOAU-UHFFFAOYSA-M 0.000 abstract 1
- 229920002905 Colesevelam Polymers 0.000 abstract 1
- 201000005569 Gout Diseases 0.000 abstract 1
- KHNXRSIBRKBJDI-UHFFFAOYSA-N Sevelamer hydrochloride Chemical compound Cl.NCC=C.ClCC1CO1 KHNXRSIBRKBJDI-UHFFFAOYSA-N 0.000 abstract 1
- 229960001152 colesevelam Drugs 0.000 abstract 1
- 229920001577 copolymer Polymers 0.000 abstract 1
- 229920006037 cross link polymer Polymers 0.000 abstract 1
- ZBCBWPMODOFKDW-UHFFFAOYSA-N diethanolamine Chemical compound OCCNCCO ZBCBWPMODOFKDW-UHFFFAOYSA-N 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000002243 precursor Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 229960003027 sevelamer hydrochloride Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/74—Synthetic polymeric materials
- A61K31/785—Polymers containing nitrogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
Landscapes
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Dental Preparations (AREA)
- Adhesives Or Adhesive Processes (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US28444501P | 2001-04-18 | 2001-04-18 | |
| US30556701P | 2001-07-13 | 2001-07-13 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE380553T1 true ATE380553T1 (de) | 2007-12-15 |
Family
ID=26962624
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02726732T ATE380553T1 (de) | 2001-04-18 | 2002-04-10 | Aminpolymere zur behandlung von gicht und zur senkung des harnsäuregehaltes |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US20030039627A1 (enExample) |
| EP (1) | EP1416942B1 (enExample) |
| JP (1) | JP2004528332A (enExample) |
| AT (1) | ATE380553T1 (enExample) |
| BR (1) | BR0209133A (enExample) |
| CA (1) | CA2444347A1 (enExample) |
| DE (1) | DE60224052T2 (enExample) |
| MX (1) | MXPA03009571A (enExample) |
| WO (1) | WO2002085381A1 (enExample) |
Families Citing this family (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6733780B1 (en) | 1999-10-19 | 2004-05-11 | Genzyme Corporation | Direct compression polymer tablet core |
| US7220406B2 (en) * | 2002-10-22 | 2007-05-22 | Genzyme Corporation | Method for promoting bone formation |
| WO2004099288A1 (en) * | 2003-05-09 | 2004-11-18 | Carlsberg A/S | Polyethyleneimine polymers |
| US7449605B2 (en) * | 2003-11-03 | 2008-11-11 | Ilypsa, Inc. | Crosslinked amine polymers |
| US7459502B2 (en) * | 2003-11-03 | 2008-12-02 | Ilypsa, Inc. | Pharmaceutical compositions comprising crosslinked polyamine polymers |
| US7767768B2 (en) * | 2003-11-03 | 2010-08-03 | Ilypsa, Inc. | Crosslinked amine polymers |
| US7385012B2 (en) | 2003-11-03 | 2008-06-10 | Ilypsa, Inc. | Polyamine polymers |
| US7608674B2 (en) * | 2003-11-03 | 2009-10-27 | Ilypsa, Inc. | Pharmaceutical compositions comprising cross-linked small molecule amine polymers |
| US7335795B2 (en) * | 2004-03-22 | 2008-02-26 | Ilypsa, Inc. | Crosslinked amine polymers |
| US7985418B2 (en) | 2004-11-01 | 2011-07-26 | Genzyme Corporation | Aliphatic amine polymer salts for tableting |
| WO2006072054A1 (en) * | 2004-12-30 | 2006-07-06 | Genzyme Corporation | Zinc-containing treatments for hyperphosphatemia |
| WO2006121995A2 (en) * | 2005-05-09 | 2006-11-16 | Tap Pharmaceutical Products, Inc. | Methods for treating nephrolithiasis |
| JP2009507019A (ja) * | 2005-09-02 | 2009-02-19 | ジェンザイム・コーポレーション | リン酸塩を除去する方法およびそれに使用される重合体 |
| CN103027896B (zh) | 2005-09-15 | 2016-01-20 | 基酶有限公司 | 胺聚合物的小袋制剂 |
| CA2626734A1 (en) * | 2005-11-08 | 2007-05-18 | Genzyme Corporation | Magnesium-containing polymers for the treatment of hyperphosphatemia |
| JP2009536246A (ja) * | 2006-05-05 | 2009-10-08 | ゲンズイメ コーポレーション | ホスフェート捕捉剤としてのアミン縮合重合体 |
| US20100135950A1 (en) * | 2006-07-05 | 2010-06-03 | Genzyme Corporation | Iron(II)-Containing Treatments for Hyperphosphatemia |
| US20100124542A1 (en) * | 2006-07-18 | 2010-05-20 | Genzyme Corporation | Amine dendrimers |
| BRPI0717545A2 (pt) | 2006-09-29 | 2013-10-22 | Gezyme Corp | Composição farmacêutica, método para tratar uma doença, polímero de amida, rede de polímero, e, método para preparar um polímero de amida |
| US20090124623A1 (en) * | 2006-11-13 | 2009-05-14 | Christopher Lademacher | Methods for preserving and/or increasing renal function using xanthine oxidoreductase inhibitors |
| CA2669935A1 (en) * | 2006-11-13 | 2008-05-29 | Takeda Pharmaceuticals North America, Inc. | Methods for preserving renal function using xanthine oxidoreductase inhibitors |
| JP2010513271A (ja) * | 2006-12-14 | 2010-04-30 | ゲンズイメ コーポレーション | アミド−アミンポリマー組成物 |
| RU2009131454A (ru) * | 2007-01-19 | 2011-02-27 | Такеда Фармасьютикалз Норт Америка, Инк. (Us) | Способы предупреждения или уменьшения числа обострений подагры с применением ингибиторов ксантиноксидоредуктазы и противовоспалительных средств |
| US20100129309A1 (en) * | 2007-02-23 | 2010-05-27 | Dhal Pradeep K | Amine polymer compositions |
| US20100196305A1 (en) * | 2007-03-08 | 2010-08-05 | Dhal Pradeep K | Sulfone polymer compositions |
| EP2152277A1 (en) * | 2007-04-27 | 2010-02-17 | Genzyme Corporation | Amido-amine dendrimer compositions |
| JP2011506449A (ja) * | 2007-12-14 | 2011-03-03 | ジェンザイム コーポレーション | コーティング医薬組成物 |
| WO2009154747A1 (en) * | 2008-06-20 | 2009-12-23 | Genzyme Corporation | Pharmaceutical compositions |
| US20100311756A1 (en) * | 2009-01-22 | 2010-12-09 | Takeda Pharmaceuticals North America, Inc. | Methods for delaying the progression of at least one of cardiac hypertrophy, cardiac remodeling or left ventricular function or the onset of heart failure in subjects in need of treatment thereof |
| JP5978216B2 (ja) | 2010-09-10 | 2016-08-24 | タケダ ファーマシューティカルズ ユー．エス．エー． インコーポレイティド | テオフィリンとフェブキソスタットの併用療法のための方法 |
| KR102633597B1 (ko) | 2013-06-05 | 2024-02-06 | 트리시다, 인크. | 경구 투여를 위한 양성자-결합 중합체 |
| IL322207A (en) | 2014-12-10 | 2025-09-01 | Tricida Inc | Proton-binding polymers for oral administration |
| IL262660B2 (en) | 2016-05-06 | 2024-04-01 | Tricida Inc | Compositions for and method of treating acid-base disorders |
| JP6792640B2 (ja) | 2016-12-28 | 2020-11-25 | 富士フイルム株式会社 | 窒素原子含有ポリマー又はその塩の乳化液、その製造方法、及び粒子の製造方法 |
| EP3698799B1 (en) | 2017-10-16 | 2022-01-26 | FUJIFILM Corporation | Hyperphosphatemia treatment agent |
| IL319146A (en) | 2017-11-03 | 2025-04-01 | Tricida Inc | Compositions for and method of treating acid-base disorders |
| EP4164659B1 (en) * | 2021-08-24 | 2024-03-27 | Waterstone Pharmaceuticals (Wuhan) Co., Ltd. | Polymers, compositions and methods for treating hyperuricemia |
| ES2995007T3 (en) * | 2021-08-24 | 2025-02-05 | Waterstone Pharmaceuticals Wuhan Co Ltd | Polymers, compositions and methods for treating hyperuricemia |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4271191A (en) * | 1979-12-19 | 1981-06-02 | Pierre Fabre S.A. | Method of treating hyperuricemia and gout |
| DE3727082A1 (de) * | 1987-08-14 | 1989-02-23 | Goedecke Ag | Pharmazeutische zubereitungen zur behandlung der urolithiasis |
| WO1998017707A1 (en) * | 1996-10-23 | 1998-04-30 | The Dow Chemical Company | Water-soluble polymers for the reduction of dietary phosphate or oxalate absorption |
| US5985938A (en) * | 1997-11-05 | 1999-11-16 | Geltex Pharmaceuticals, Inc. | Method for reducing oxalate |
| WO2002085380A1 (en) * | 2001-04-18 | 2002-10-31 | Geltex Pharmaceuticals, Inc. | Method for treating gout and reducing serum uric acid |
-
2002
- 2002-04-10 CA CA002444347A patent/CA2444347A1/en not_active Abandoned
- 2002-04-10 JP JP2002582954A patent/JP2004528332A/ja active Pending
- 2002-04-10 AT AT02726732T patent/ATE380553T1/de not_active IP Right Cessation
- 2002-04-10 WO PCT/US2002/011492 patent/WO2002085381A1/en not_active Ceased
- 2002-04-10 EP EP02726732A patent/EP1416942B1/en not_active Expired - Lifetime
- 2002-04-10 MX MXPA03009571A patent/MXPA03009571A/es unknown
- 2002-04-10 BR BR0209133-0A patent/BR0209133A/pt not_active IP Right Cessation
- 2002-04-10 DE DE60224052T patent/DE60224052T2/de not_active Expired - Lifetime
- 2002-04-17 US US10/125,685 patent/US20030039627A1/en not_active Abandoned
-
2007
- 2007-06-18 US US11/820,292 patent/US20080112918A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20030039627A1 (en) | 2003-02-27 |
| WO2002085381A1 (en) | 2002-10-31 |
| US20080112918A1 (en) | 2008-05-15 |
| DE60224052D1 (de) | 2008-01-24 |
| DE60224052T2 (de) | 2008-11-06 |
| EP1416942A1 (en) | 2004-05-12 |
| CA2444347A1 (en) | 2002-10-31 |
| BR0209133A (pt) | 2004-06-15 |
| EP1416942B1 (en) | 2007-12-12 |
| JP2004528332A (ja) | 2004-09-16 |
| MXPA03009571A (es) | 2004-02-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |