ATE377588T1 - Zwischenprodukt für die herstellung von pioglitazon - Google Patents

Zwischenprodukt für die herstellung von pioglitazon

Info

Publication number
ATE377588T1
ATE377588T1 AT04731028T AT04731028T ATE377588T1 AT E377588 T1 ATE377588 T1 AT E377588T1 AT 04731028 T AT04731028 T AT 04731028T AT 04731028 T AT04731028 T AT 04731028T AT E377588 T1 ATE377588 T1 AT E377588T1
Authority
AT
Austria
Prior art keywords
pioglitazone
production
intermediate product
product
Prior art date
Application number
AT04731028T
Other languages
English (en)
Inventor
Lopez Ernesto Duran
Original Assignee
Medichem Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medichem Sa filed Critical Medichem Sa
Application granted granted Critical
Publication of ATE377588T1 publication Critical patent/ATE377588T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/54Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/55Acids; Esters
AT04731028T 2003-05-09 2004-05-04 Zwischenprodukt für die herstellung von pioglitazon ATE377588T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES200301075A ES2219180B1 (es) 2003-05-09 2003-05-09 Compuesto intermedio util para la preparacion de pioglitazona.

Publications (1)

Publication Number Publication Date
ATE377588T1 true ATE377588T1 (de) 2007-11-15

Family

ID=33427384

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04731028T ATE377588T1 (de) 2003-05-09 2004-05-04 Zwischenprodukt für die herstellung von pioglitazon

Country Status (10)

Country Link
US (1) US7375231B2 (de)
EP (1) EP1623977B1 (de)
AR (1) AR044267A1 (de)
AT (1) ATE377588T1 (de)
CA (1) CA2525190A1 (de)
DE (1) DE602004009917T2 (de)
ES (2) ES2219180B1 (de)
PL (1) PL1623977T3 (de)
PT (1) PT1623977E (de)
WO (1) WO2004099147A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090111828A1 (en) * 2005-11-23 2009-04-30 Astrazeneca Ab L-alanine derivatives
WO2008093065A1 (en) * 2007-01-29 2008-08-07 Astrazeneca Ab L-ALANINE DERIVATIVES AS α5βL ANTAGONISTS
WO2008125811A1 (en) * 2007-04-11 2008-10-23 Astrazeneca Ab N-[HETEROARYLCARBONYL]-S-THIENYL-L-ALANINE DERIVATIVES AS α5β1 ANTAGONISTS
WO2012177956A1 (en) * 2011-06-23 2012-12-27 Metabolic Solutions Development Comapny, Llc Ppar-sparing compounds for use in the treatment of diabetes and other metabolic diseases

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR240698A1 (es) * 1985-01-19 1990-09-28 Takeda Chemical Industries Ltd Procedimiento para preparar compuestos de 5-(4-(2-(5-etil-2-piridil)-etoxi)benzil)-2,4-tiazolidindiona y sus sales
JPH08325263A (ja) * 1995-05-31 1996-12-10 Sumitomo Metal Ind Ltd 新規2−アミノ−3−フェニルプロピオン酸誘導体
JP2000344748A (ja) * 1999-03-29 2000-12-12 Welfide Corp 3−芳香族置換プロピオン酸またはアクリル酸化合物
ATE355286T1 (de) * 2001-04-26 2006-03-15 Zentiva As Verfahren zur herstellung von pioglitazone als antidiabetisches mitttel

Also Published As

Publication number Publication date
PT1623977E (pt) 2008-01-22
PL1623977T3 (pl) 2008-04-30
DE602004009917T2 (de) 2008-08-21
DE602004009917D1 (de) 2007-12-20
US20070083050A1 (en) 2007-04-12
US7375231B2 (en) 2008-05-20
EP1623977B1 (de) 2007-11-07
ES2219180B1 (es) 2006-03-01
AR044267A1 (es) 2005-09-07
WO2004099147A1 (es) 2004-11-18
CA2525190A1 (en) 2004-11-18
ES2297415T3 (es) 2008-05-01
EP1623977A1 (de) 2006-02-08
ES2219180A1 (es) 2004-11-16

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Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties