ATE373240T1 - Auf fluoreszenzpolarisation beruhender homogener assay für aflatoxine - Google Patents

Auf fluoreszenzpolarisation beruhender homogener assay für aflatoxine

Info

Publication number
ATE373240T1
ATE373240T1 AT02752236T AT02752236T ATE373240T1 AT E373240 T1 ATE373240 T1 AT E373240T1 AT 02752236 T AT02752236 T AT 02752236T AT 02752236 T AT02752236 T AT 02752236T AT E373240 T1 ATE373240 T1 AT E373240T1
Authority
AT
Austria
Prior art keywords
fluorescence polarization
aflatoxin
aflatoxins
tracer
mixture
Prior art date
Application number
AT02752236T
Other languages
English (en)
Inventor
Mohammad Nasir
Michael Jolley
Original Assignee
Diachemix Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Diachemix Llc filed Critical Diachemix Llc
Application granted granted Critical
Publication of ATE373240T1 publication Critical patent/ATE373240T1/de

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/542Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT02752236T 2001-07-13 2002-07-10 Auf fluoreszenzpolarisation beruhender homogener assay für aflatoxine ATE373240T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US90545201A 2001-07-13 2001-07-13

Publications (1)

Publication Number Publication Date
ATE373240T1 true ATE373240T1 (de) 2007-09-15

Family

ID=25420843

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02752236T ATE373240T1 (de) 2001-07-13 2002-07-10 Auf fluoreszenzpolarisation beruhender homogener assay für aflatoxine

Country Status (10)

Country Link
US (1) US7811775B2 (de)
EP (1) EP1407272B1 (de)
CN (1) CN1245629C (de)
AT (1) ATE373240T1 (de)
BR (1) BRPI0211116B1 (de)
CA (1) CA2452493C (de)
DE (1) DE60222423T2 (de)
ES (2) ES2292787T3 (de)
PT (1) PT1407272E (de)
WO (1) WO2003006994A1 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1322327C (zh) * 2005-04-15 2007-06-20 中国农业科学院油料作物研究所 一种黄曲霉毒素b1的速测方法
ITMO20110109A1 (it) * 2011-05-11 2012-11-12 Generon S R L Metodo per l'analisi di aflatossine nel latte e nei derivati del latte
US11035764B2 (en) * 2012-02-03 2021-06-15 Charm Sciences, Inc. Extraction of mycotoxins
CN103217528B (zh) * 2012-11-30 2014-04-09 中国农业科学院油料作物研究所 一种检测黄曲霉毒素b1含量的非标记免疫分析方法
CN103116024B (zh) * 2012-11-30 2014-04-09 中国农业科学院油料作物研究所 抗黄曲霉毒素通用单克隆抗体1c11在黄曲霉毒素b1荧光淬灭中的应用及方法
CN103743913B (zh) * 2014-01-23 2015-07-08 福建农林大学 快速鉴定与黄曲霉毒素b1互作的宿主蛋白的方法
CN104341432B (zh) * 2014-09-26 2016-04-27 安徽省农业科学院农产品加工研究所 一种黄曲霉毒素半抗原、人工抗原及其制备方法
CA2962710C (en) * 2014-10-20 2021-05-04 Foss Analytical A/S Determination of analytes in a sample matrix by solvent extraction
CN107129989B (zh) * 2017-05-17 2021-02-05 中国科学院生态环境研究中心 检测黄曲霉毒素的核酸适配体、试剂盒及其检测方法
CN112230001A (zh) * 2020-10-10 2021-01-15 河南农业大学 一种检测黄曲霉m1的可视化免疫分析方法
CN113640510B (zh) * 2021-06-01 2023-06-27 中国农业科学院油料作物研究所 农产品黄曲霉毒素分子预警方法
CN114140422B (zh) * 2021-11-26 2024-08-20 合肥工业大学 一种荧光与多光谱成像融合的黄曲霉毒素检测建模方法

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4444879A (en) * 1981-01-29 1984-04-24 Science Research Center, Inc. Immunoassay with article having support film and immunological counterpart of analyte
US4772551A (en) 1985-12-26 1988-09-20 Neogen Corporation Method and test kit for detecting a trichothecene using novel monoclonal antibodies
US5166078A (en) * 1986-08-19 1992-11-24 Idexx Laboratories, Inc. Hapten-macromolecule conjugates useful in hapten assays
US4835100A (en) * 1986-10-31 1989-05-30 Neogen Corporation Method and test kit for detecting an aflatoxin B1 and G1 using novel monoclonal antibodies
US5427960A (en) * 1987-03-27 1995-06-27 Abbott Laboratories Fluorescence polarization assay for cyclosporin A and metabolites and related immunogens and antibodies
US5051361A (en) * 1988-10-19 1991-09-24 Sigma Chemical Company AZT immunoassays, derivatives, conjugates and antibodies
US5262333A (en) * 1988-10-28 1993-11-16 Abbott Laboratories Method and reagents for detecting amphetamine and/or D-methamphetamine in biological samples
US5171686A (en) 1989-11-29 1992-12-15 The United States Of America As Represented By The United States Department Of Agriculture Use of native Aspergillus flavus strains to prevent aflatoxin contamination
US5314804A (en) * 1992-03-24 1994-05-24 Serim Research Corporation Test for Helicobacter pylori
EP0651253A1 (de) * 1993-11-02 1995-05-03 Abbott Laboratories Immunoassay zum Nachweis menschlicher Autoantikörper
US5976820A (en) 1995-08-28 1999-11-02 Jolley; Michael E. Detection of antibodies to bacterial antigens by flourescence polarization
US5952187A (en) * 1995-12-01 1999-09-14 Oxis International, Inc. Topiramate immunoassay
CN1157602C (zh) 1997-09-05 2004-07-14 松下电器产业株式会社 荧光偏振法检测样品的方法及其中使用的试剂
US6812036B2 (en) 2000-09-11 2004-11-02 Diachemix Llc Fluorescence polarization-based homogeneous assay for deoxynivalenol determination in grains
US6482601B1 (en) 2000-09-11 2002-11-19 Diachemix Llc Fluorescence polarization-based homogeneous assay for fumonisin determination in grains
US7087389B2 (en) 2001-02-09 2006-08-08 Council Of Scientific & Industrial Research Highly cost-effective analytical device for performing immunoassays with ultra high sensitivity

Also Published As

Publication number Publication date
US20080227221A1 (en) 2008-09-18
ES2356379T3 (es) 2011-04-07
PT1407272E (pt) 2007-11-21
EP1407272A1 (de) 2004-04-14
ES2292787T3 (es) 2008-03-16
CA2452493C (en) 2008-04-15
BRPI0211116B1 (pt) 2015-10-13
BR0211116A (pt) 2004-12-14
WO2003006994A1 (en) 2003-01-23
CN1527942A (zh) 2004-09-08
CA2452493A1 (en) 2003-01-23
DE60222423T2 (de) 2008-06-19
EP1407272B1 (de) 2007-09-12
US7811775B2 (en) 2010-10-12
EP1407272A4 (de) 2005-09-14
DE60222423D1 (de) 2007-10-25
CN1245629C (zh) 2006-03-15

Similar Documents

Publication Publication Date Title
CY1107872T1 (el) Βασισμενη σε πολωση φθορισμου ομοioγενης δοκιμασια για τον προσδιορισμο δεοξυνιβαλενολης στα δημητριακα
ATE373240T1 (de) Auf fluoreszenzpolarisation beruhender homogener assay für aflatoxine
ATE386936T1 (de) Selbst-kalibrierendes system für magnetisches bindungs-verfahren
CN101256191A (zh) 基于磁珠和纳米金探针的微量蛋白质的测定方法
ATE206520T1 (de) Empfindlicher immuntest, der antikörperkonjugate mit replizierbaren dns-matrizen verwendet
ATE447712T1 (de) Immunoassay mit doppelter standardkurve
ATE469351T1 (de) Turbidimetrischer immunoassay zur beurteilung von humanem cystatin c
Zhang et al. An indirect competitive fluorescence immunoassay for determination of dicyclohexyl phthalate in water samples
WO2012159072A3 (en) Fluorescent molecular probes for use in assays that measure test compound competitive binding with sam-utilizing proteins
Hu et al. Detection of microcystins in environmental samples using surface plasmon resonance biosensor
Li et al. Enzyme–antibody dual labeled gold nanoparticles probe for ultrasensitive detection of κ-casein in bovine milk samples
CN205193076U (zh) 一种生物素-亲和素系统快速检测卡
Liu et al. Rapid detection of Escherichia coli O157: H7 in milk, bread, and jelly by lac dye coloration‐based bidirectional lateral flow immunoassay strip
Kim et al. In situ immuno-magnetic concentration-based biosensor systems for the rapid detection of Listeria monocytogenes
ATE313795T1 (de) Auf fluoreszenz-polarisation basierender homogener test für die fumonisinbestimmung in körnern
ATE240522T1 (de) Chemilumineszenz-immunoassay zum nachweis eines mit der chagas-erkränkung verbundenen analyts in einer probe
CN204330781U (zh) 脂蛋白磷脂酶a2免疫层析定量检测试纸条
CN102942519B (zh) 烯啶虫胺半抗原、人工抗原和抗体及其制备方法与应用
EP0380019A3 (de) Fluoreszenz-Polarisationsimmunoassay für Methadon
CN204287192U (zh) 髓过氧化物酶免疫层析定量检测试纸条
CN107219216A (zh) 一种化学发光免疫检测婴儿米粉中黄曲霉毒素b1的方法
WO2003008929A3 (en) Particle analysis as a detection system for particle-enhanced assays
CN107202891B (zh) 一种黄曲霉毒素b1免疫快速检测装置和检测方法
Liu et al. Portable system for rapid field test of CEA in human serum based on chemiluminescence enzyme immunoassay
EP1881324A3 (de) Polarisationsbasierter, homogener Fluoreszenz-Assay zur Bestimmung von Deoxynivalenol in Körnern

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties