ATE371014T1 - Verfahren zur herstellung von biologischen substanzen durch perfusionskultivierung von suspendierten tierischen zellen - Google Patents
Verfahren zur herstellung von biologischen substanzen durch perfusionskultivierung von suspendierten tierischen zellenInfo
- Publication number
- ATE371014T1 ATE371014T1 AT04730939T AT04730939T ATE371014T1 AT E371014 T1 ATE371014 T1 AT E371014T1 AT 04730939 T AT04730939 T AT 04730939T AT 04730939 T AT04730939 T AT 04730939T AT E371014 T1 ATE371014 T1 AT E371014T1
- Authority
- AT
- Austria
- Prior art keywords
- animal cells
- biological substances
- producing biological
- suspended animal
- culture medium
- Prior art date
Links
- 239000000126 substance Substances 0.000 title abstract 3
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 230000010412 perfusion Effects 0.000 title abstract 2
- 239000006143 cell culture medium Substances 0.000 abstract 3
- 239000002736 nonionic surfactant Substances 0.000 abstract 2
- 210000004102 animal cell Anatomy 0.000 abstract 1
- 210000004027 cell Anatomy 0.000 abstract 1
- 238000012258 culturing Methods 0.000 abstract 1
- 238000001914 filtration Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 210000002966 serum Anatomy 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/0018—Culture media for cell or tissue culture
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/26—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against hormones ; against hormone releasing or inhibiting factors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M3/00—Tissue, human, animal or plant cell, or virus culture apparatus
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/50—Soluble polymers, e.g. polyethyleneglycol [PEG]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2510/00—Genetically modified cells
- C12N2510/02—Cells for production
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Cell Biology (AREA)
- Biophysics (AREA)
- Immunology (AREA)
- Endocrinology (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Virology (AREA)
- Sustainable Development (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP03101205 | 2003-05-01 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE371014T1 true ATE371014T1 (de) | 2007-09-15 |
Family
ID=33395963
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT04730939T ATE371014T1 (de) | 2003-05-01 | 2004-05-03 | Verfahren zur herstellung von biologischen substanzen durch perfusionskultivierung von suspendierten tierischen zellen |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20070065907A1 (de) |
| EP (1) | EP1620549B1 (de) |
| JP (1) | JP2006525015A (de) |
| KR (1) | KR20060015568A (de) |
| CN (1) | CN100432217C (de) |
| AT (1) | ATE371014T1 (de) |
| AU (1) | AU2004235017B2 (de) |
| CA (1) | CA2523792A1 (de) |
| DE (1) | DE602004008451T2 (de) |
| DK (1) | DK1620549T3 (de) |
| ES (1) | ES2290705T3 (de) |
| WO (1) | WO2004097006A1 (de) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ITRM20060020A1 (it) * | 2006-01-18 | 2007-07-19 | Andrea Masotti | Metodo per la coltura di cellule |
| PT2634243T (pt) | 2006-07-14 | 2017-12-18 | Patheon Holdings I B V | Método para melhorar a cultura de células |
| EP2625262B1 (de) * | 2010-10-05 | 2015-09-23 | Novo Nordisk Health Care AG | Verfahren zur proteinherstellung |
| WO2012149197A2 (en) | 2011-04-27 | 2012-11-01 | Abbott Laboratories | Methods for controlling the galactosylation profile of recombinantly-expressed proteins |
| US9150645B2 (en) | 2012-04-20 | 2015-10-06 | Abbvie, Inc. | Cell culture methods to reduce acidic species |
| US9067990B2 (en) | 2013-03-14 | 2015-06-30 | Abbvie, Inc. | Protein purification using displacement chromatography |
| US9181572B2 (en) | 2012-04-20 | 2015-11-10 | Abbvie, Inc. | Methods to modulate lysine variant distribution |
| US9249182B2 (en) | 2012-05-24 | 2016-02-02 | Abbvie, Inc. | Purification of antibodies using hydrophobic interaction chromatography |
| AU2013309506A1 (en) | 2012-09-02 | 2015-03-12 | Abbvie Inc. | Methods to control protein heterogeneity |
| US9512214B2 (en) | 2012-09-02 | 2016-12-06 | Abbvie, Inc. | Methods to control protein heterogeneity |
| SG11201507230PA (en) | 2013-03-12 | 2015-10-29 | Abbvie Inc | Human antibodies that bind human tnf-alpha and methods of preparing the same |
| US20140271633A1 (en) * | 2013-03-14 | 2014-09-18 | Abbvie Inc. | Mammalian cell culture performance through surfactant supplementation of feed media |
| US9499614B2 (en) | 2013-03-14 | 2016-11-22 | Abbvie Inc. | Methods for modulating protein glycosylation profiles of recombinant protein therapeutics using monosaccharides and oligosaccharides |
| US9017687B1 (en) | 2013-10-18 | 2015-04-28 | Abbvie, Inc. | Low acidic species compositions and methods for producing and using the same using displacement chromatography |
| WO2015051293A2 (en) | 2013-10-04 | 2015-04-09 | Abbvie, Inc. | Use of metal ions for modulation of protein glycosylation profiles of recombinant proteins |
| US9085618B2 (en) | 2013-10-18 | 2015-07-21 | Abbvie, Inc. | Low acidic species compositions and methods for producing and using the same |
| US9181337B2 (en) | 2013-10-18 | 2015-11-10 | Abbvie, Inc. | Modulated lysine variant species compositions and methods for producing and using the same |
| US20150139988A1 (en) | 2013-11-15 | 2015-05-21 | Abbvie, Inc. | Glycoengineered binding protein compositions |
| WO2022026451A1 (en) * | 2020-07-30 | 2022-02-03 | Amgen Inc. | Cell culture media and methods of making and using the same |
| CN114317392A (zh) * | 2021-12-27 | 2022-04-12 | 无锡药明生物技术股份有限公司 | 优化细胞培养的方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5372943A (en) * | 1987-07-24 | 1994-12-13 | Cetus Corporation | Lipid microemulsions for culture media |
| US5378612A (en) * | 1990-05-11 | 1995-01-03 | Juridical Foundation The Chemo-Sero-Therapeutic Research Institute | Culture medium for production of recombinant protein |
| EP0968284B1 (de) * | 1996-11-20 | 2006-12-13 | Introgen Therapeutics, Inc. | Ein verbessertes verfahren zur produktion und reinigung von adenoviralen vektoren |
-
2004
- 2004-05-03 AT AT04730939T patent/ATE371014T1/de not_active IP Right Cessation
- 2004-05-03 KR KR1020057020674A patent/KR20060015568A/ko not_active Ceased
- 2004-05-03 ES ES04730939T patent/ES2290705T3/es not_active Expired - Lifetime
- 2004-05-03 EP EP04730939A patent/EP1620549B1/de not_active Expired - Lifetime
- 2004-05-03 CN CNB2004800117912A patent/CN100432217C/zh not_active Expired - Fee Related
- 2004-05-03 WO PCT/NL2004/000300 patent/WO2004097006A1/en not_active Ceased
- 2004-05-03 DK DK04730939T patent/DK1620549T3/da active
- 2004-05-03 JP JP2006507879A patent/JP2006525015A/ja not_active Withdrawn
- 2004-05-03 AU AU2004235017A patent/AU2004235017B2/en not_active Expired - Fee Related
- 2004-05-03 US US10/554,293 patent/US20070065907A1/en not_active Abandoned
- 2004-05-03 DE DE602004008451T patent/DE602004008451T2/de not_active Expired - Fee Related
- 2004-05-03 CA CA002523792A patent/CA2523792A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| WO2004097006A1 (en) | 2004-11-11 |
| JP2006525015A (ja) | 2006-11-09 |
| AU2004235017B2 (en) | 2009-06-04 |
| DE602004008451T2 (de) | 2008-05-15 |
| DE602004008451D1 (de) | 2007-10-04 |
| DK1620549T3 (da) | 2007-11-05 |
| CA2523792A1 (en) | 2004-11-11 |
| CN1780905A (zh) | 2006-05-31 |
| EP1620549A1 (de) | 2006-02-01 |
| KR20060015568A (ko) | 2006-02-17 |
| AU2004235017A1 (en) | 2004-11-11 |
| EP1620549B1 (de) | 2007-08-22 |
| US20070065907A1 (en) | 2007-03-22 |
| CN100432217C (zh) | 2008-11-12 |
| ES2290705T3 (es) | 2008-02-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 1620549 Country of ref document: EP |
|
| REN | Ceased due to non-payment of the annual fee |