ATE369840T1 - Orale zusammensetzungen von itraconazol und verfahren zu herstellung derselbigen - Google Patents

Orale zusammensetzungen von itraconazol und verfahren zu herstellung derselbigen

Info

Publication number
ATE369840T1
ATE369840T1 AT02700887T AT02700887T ATE369840T1 AT E369840 T1 ATE369840 T1 AT E369840T1 AT 02700887 T AT02700887 T AT 02700887T AT 02700887 T AT02700887 T AT 02700887T AT E369840 T1 ATE369840 T1 AT E369840T1
Authority
AT
Austria
Prior art keywords
itraconazole
acid
working solution
particles
coated particles
Prior art date
Application number
AT02700887T
Other languages
English (en)
Inventor
Ranga Namburi
John Kerr
Original Assignee
Stiefel Laboratories
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Stiefel Laboratories filed Critical Stiefel Laboratories
Application granted granted Critical
Publication of ATE369840T1 publication Critical patent/ATE369840T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
    • A61K9/1676—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface having a drug-free core with discrete complete coating layer containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
AT02700887T 2001-02-06 2002-02-01 Orale zusammensetzungen von itraconazol und verfahren zu herstellung derselbigen ATE369840T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US26665301P 2001-02-06 2001-02-06
US09/933,032 US6663897B2 (en) 2001-02-06 2001-08-20 Oral itraconazole formulations and methods of making the same

Publications (1)

Publication Number Publication Date
ATE369840T1 true ATE369840T1 (de) 2007-09-15

Family

ID=26951964

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02700887T ATE369840T1 (de) 2001-02-06 2002-02-01 Orale zusammensetzungen von itraconazol und verfahren zu herstellung derselbigen

Country Status (9)

Country Link
US (1) US6663897B2 (de)
EP (1) EP1357899B1 (de)
JP (1) JP2004521897A (de)
AT (1) ATE369840T1 (de)
AU (1) AU2002233822A1 (de)
CA (1) CA2437372A1 (de)
DE (1) DE60221795T2 (de)
MX (1) MXPA03006980A (de)
WO (1) WO2002062318A2 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0015239D0 (en) * 2000-06-21 2000-08-16 Biochemie Gmbh Organic compounds
US8071133B2 (en) 2001-08-20 2011-12-06 Stiefel Laboratories, Inc. Oral dosage forms of water insoluble drugs and methods of making the same
US20040115266A1 (en) * 2002-02-01 2004-06-17 Namburi Ranga Raju Oral itraconazole formulations and methods of making the same
WO2003101392A2 (en) 2002-05-31 2003-12-11 Transform Pharmaceuticals, Inc. Novel conazole crystalline forms and related processes, pharmaceutical compositions and methods
US7927613B2 (en) 2002-02-15 2011-04-19 University Of South Florida Pharmaceutical co-crystal compositions
US7446107B2 (en) 2002-02-15 2008-11-04 Transform Pharmaceuticals, Inc. Crystalline forms of conazoles and methods of making and using the same
US7790905B2 (en) 2002-02-15 2010-09-07 Mcneil-Ppc, Inc. Pharmaceutical propylene glycol solvate compositions
US20030224006A1 (en) 2002-03-01 2003-12-04 Zaworotko Michael J. Multiple-component solid phases containing at least one active pharmaceutical ingredient
GB0205253D0 (en) * 2002-03-06 2002-04-17 Univ Gent Immediate release pharmaceutical granule compositions and a continuous process for making them
JP2006500377A (ja) 2002-06-21 2006-01-05 トランスフォーム・ファーマシューティカルズ・インコーポレイテッド 改善された溶解性を有する医薬組成物
EP1539111A1 (de) * 2002-08-05 2005-06-15 DSM IP Assets B.V. Orale dosierformen von wasserunl slichen arzneimitteln und herstellungsverfahren daf r
US8183290B2 (en) 2002-12-30 2012-05-22 Mcneil-Ppc, Inc. Pharmaceutically acceptable propylene glycol solvate of naproxen
US20050074494A1 (en) * 2003-10-06 2005-04-07 Xiu-Xiu Cheng Itraconazole immediate release formulation
US20050118265A1 (en) * 2003-11-28 2005-06-02 Anandi Krishnan Antifungal oral dosage forms and the methods for preparation
GB0612695D0 (en) * 2006-06-27 2006-08-09 Univ Gent Process for preparing a solid dosage form

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4791111A (en) 1985-12-23 1988-12-13 Janssen Pharmaceutica, N.V. [[4-[4-(4-phenyl-1-piperazinyl)phenoxymethyl]-1,3-dioxolan-2-yl]methyl]-1H-imidazoles and 1H-1,2,4-triazoles having anti-microbial properties
PH30929A (en) * 1992-09-03 1997-12-23 Janssen Pharmaceutica Nv Beads having a core coated with an antifungal and a polymer.
IT1263831B (it) 1993-01-29 1996-09-04 Paolo Chiesi Complessi di inclusione multicomponente ad elevata solubilita' costituiti da un farmaco di tipo basico, un acido ed una ciclodestrina
HUP9903869A3 (en) * 1996-06-28 2000-07-28 Schering Corp Oral composition comprising a triazole antifungal compound
FR2758461A1 (fr) 1997-01-17 1998-07-24 Pharma Pass Composition pharmaceutique presentant une biodisponibilite elevee et son procede de preparation
PT969821E (pt) * 1997-03-26 2003-10-31 Janssen Pharmaceutica Nv Pastilhas tendo um nucleo revestido com um antifungico e um polimero
SI1104291T1 (sl) * 1998-07-17 2006-02-28 Janssen Pharmaceutica Nv Pelete, ki imajo jedro oblozeno s fungicidom in polimerom
WO2000030616A1 (en) 1998-11-20 2000-06-02 Rtp Pharma Inc. Dispersible phospholipid stabilized microparticles
BR0009176A (pt) 1999-03-24 2001-12-18 Fmc Corp Partìcula granular, forma de dosagem, métodopara preparar uma partìcula granular, misturaseca, e, formulação granular
US6383471B1 (en) * 1999-04-06 2002-05-07 Lipocine, Inc. Compositions and methods for improved delivery of ionizable hydrophobic therapeutic agents
KR100331529B1 (ko) 1999-06-16 2002-04-06 민경윤 난용성 항진균제의 경구투여용 조성물 및 그의 제조 방법

Also Published As

Publication number Publication date
DE60221795D1 (de) 2007-09-27
DE60221795T2 (de) 2007-12-27
JP2004521897A (ja) 2004-07-22
WO2002062318A2 (en) 2002-08-15
MXPA03006980A (es) 2004-10-15
CA2437372A1 (en) 2002-08-15
US6663897B2 (en) 2003-12-16
EP1357899B1 (de) 2007-08-15
AU2002233822A1 (en) 2002-08-19
WO2002062318A3 (en) 2002-11-21
EP1357899A2 (de) 2003-11-05
US20020150620A1 (en) 2002-10-17

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Legal Events

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