DE60119905D1 - Verfahren zur herstellung fester dispersionen - Google Patents

Verfahren zur herstellung fester dispersionen

Info

Publication number
DE60119905D1
DE60119905D1 DE60119905T DE60119905T DE60119905D1 DE 60119905 D1 DE60119905 D1 DE 60119905D1 DE 60119905 T DE60119905 T DE 60119905T DE 60119905 T DE60119905 T DE 60119905T DE 60119905 D1 DE60119905 D1 DE 60119905D1
Authority
DE
Germany
Prior art keywords
methods
solid dispersions
substances
preparing solid
dispersions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60119905T
Other languages
English (en)
Other versions
DE60119905T2 (de
Inventor
Arne Brodin
Sylvan Frank
Chao Ye
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ohio State University Research Foundation
Original Assignee
Ohio State University Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from SE0000934A external-priority patent/SE0000934D0/xx
Application filed by Ohio State University Research Foundation filed Critical Ohio State University Research Foundation
Application granted granted Critical
Publication of DE60119905D1 publication Critical patent/DE60119905D1/de
Publication of DE60119905T2 publication Critical patent/DE60119905T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A61P23/02—Local anaesthetics
DE60119905T 2000-03-09 2001-03-08 Verfahren zur Herstellung von Feststoffdispersionen Expired - Lifetime DE60119905T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US18798400P 2000-03-09 2000-03-09
US187984P 2000-03-09
SE0000934A SE0000934D0 (sv) 2000-03-21 2000-03-21 Method of preparing pharmaceutical compositions
SE0000934 2000-03-21
PCT/SE2001/000499 WO2001066091A1 (en) 2000-03-09 2001-03-08 Method of preparing solid dispersions

Publications (2)

Publication Number Publication Date
DE60119905D1 true DE60119905D1 (de) 2006-06-29
DE60119905T2 DE60119905T2 (de) 2007-01-11

Family

ID=26655029

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60119905T Expired - Lifetime DE60119905T2 (de) 2000-03-09 2001-03-08 Verfahren zur Herstellung von Feststoffdispersionen

Country Status (11)

Country Link
US (1) US20030104065A1 (de)
EP (1) EP1263413B1 (de)
JP (1) JP2003525895A (de)
AT (1) ATE326949T1 (de)
AU (1) AU2001239625A1 (de)
CY (1) CY1105515T1 (de)
DE (1) DE60119905T2 (de)
DK (1) DK1263413T3 (de)
ES (1) ES2263600T3 (de)
PT (1) PT1263413E (de)
WO (1) WO2001066091A1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10026698A1 (de) 2000-05-30 2001-12-06 Basf Ag Selbstemulgierende Wirkstoffformulierung und Verwendung dieser Formulierung
US8377952B2 (en) 2003-08-28 2013-02-19 Abbott Laboratories Solid pharmaceutical dosage formulation
US8025899B2 (en) 2003-08-28 2011-09-27 Abbott Laboratories Solid pharmaceutical dosage form
DE10358749A1 (de) 2003-12-12 2005-07-14 Lts Lohmann Therapie-Systeme Ag Darreichungsform zur Bekämpfung von primären Kopfschmerzen
US8475845B2 (en) 2005-07-15 2013-07-02 Map Pharmaceuticals, Inc. Method of particle formation
WO2009011584A2 (en) * 2007-07-18 2009-01-22 Feyecon Development & Implementation B.V. A method of preparing a pharmaceutical co-crystal composition
US20120093925A1 (en) * 2009-05-29 2012-04-19 Morishita Jintan Co., Ltd. Oral medicinal composition and oral medicinal capsule having the composition encapsulated therein
EP2683359B1 (de) * 2011-03-07 2015-04-22 3M Innovative Properties Company Mikronadelvorrichtungen und verfahren
FR2987266B1 (fr) * 2012-02-28 2014-12-19 Debregeas Et Associes Pharma Procede d'obtention d'une composition pharmaceutique a base de modafinil, composition pharmaceutique ainsi obtenue et son application
WO2015071841A1 (en) 2013-11-12 2015-05-21 Druggability Technologies Holdings Limited Complexes of dabigatran and its derivatives, process for the preparation thereof and pharmaceutical compositions containing them
CN108096195B (zh) * 2018-01-08 2020-01-24 中国药科大学 超临界抗溶剂法制备阿齐沙坦固体分散体的方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5169433A (en) * 1990-07-18 1992-12-08 Formulogics, Inc. Method of preparing mixtures of active ingredients and excipients using liquid carbon dioxide
WO1994008599A1 (en) * 1992-10-14 1994-04-28 The Regents Of The University Of Colorado Ion-pairing of drugs for improved efficacy and delivery
SI9400079B (sl) * 1994-02-15 2003-02-28 Dr. Weidner Eckhard, Dipl. Ing. Postopek in naprava za pridobivanje in frakcioniranje majhnih delcev iz raztopin nasičenih s plinom
EP1097705A2 (de) * 1996-10-14 2001-05-09 F. Hoffmann-La Roche Ag Verfahren zur Herstellung eines pulverförmigen Präparates
US5955475A (en) * 1997-06-30 1999-09-21 Endo Pharmaceuticals Inc. Process for manufacturing paroxetine solid dispersions
DK1071402T3 (da) * 1998-04-09 2007-02-19 Hoffmann La Roche Fremgangsmåde til af partikler med (sub)mikronstörrelse ved oplösning i komprimeret gas og overfladeaktive stoffer
JP4693238B2 (ja) * 1998-06-19 2011-06-01 オバン・エナジー・リミテッド 水に溶けない化合物のサブミクロン粒子を生成させる方法
US20020041898A1 (en) * 2000-01-05 2002-04-11 Unger Evan C. Novel targeted delivery systems for bioactive agents

Also Published As

Publication number Publication date
AU2001239625A1 (en) 2001-09-17
CY1105515T1 (el) 2010-07-28
DE60119905T2 (de) 2007-01-11
WO2001066091A1 (en) 2001-09-13
PT1263413E (pt) 2006-08-31
DK1263413T3 (da) 2006-09-11
US20030104065A1 (en) 2003-06-05
JP2003525895A (ja) 2003-09-02
ES2263600T3 (es) 2006-12-16
EP1263413B1 (de) 2006-05-24
EP1263413A1 (de) 2002-12-11
ATE326949T1 (de) 2006-06-15

Similar Documents

Publication Publication Date Title
CY1105515T1 (el) Μεθοδος παρασκευης στερεων διασπορων
DE69906269T2 (de) Wässriges verfahren zur herstellung fester paroxetin-dispersionen
WO2007128923A3 (fr) Procede de preparation d'un gel biocompatible a libération contrôlée d'un ou de plusieurs principes actifs peu solubles dans l'eau, gels ainsi obtenus et leur utilisation
AR033548A1 (es) Composicion farmaceutica que comprende un inhibidor de lipasa, un procedimiento para su preparacion, equipo transportable a modo de ''kit'', el uso de dicha composicion en la fabricacion de medicamentos, un inhibidor de lipasa y un secuestrante de acidos biliares
TR200102314T2 (tr) Damar gelişimi inhibitörleri olarak kuinazolin türevleri.
BR9808888A (pt) Formas de dosagem e método de melhorar disfunção erétil masculina
CA2372339A1 (en) Pharmaceutical product comprising the active substance diamorphine, and its use in a process for treating opiate addiction
DE69519664D1 (de) Verfahren zur herstellung fester pharmazeutischer dosierungsform
MY129798A (en) Process for preparing a pharmaceutical composition
CR9704A (es) Composicion farmaceutica de liberacion modificada, proceso de preparacion y metodo para emplear la misma.
BRPI0716436B8 (pt) sistema de liberação controlada e método para fabricação do mesmo
DE60312333D1 (de) Einen lipophilen wirkstoff enthaltende feste pharmazeutische zusammensetzung sowie deren herstellung
BR122014001142B8 (pt) processo de produzir uma formulação em comprimido purgativa colônica para administração oral
AR082579A2 (es) Una composicion farmaceutica espontaneamente dispersable para la administracion oral, uso para la preparacion de un medicamento para el tratamiento del cancer, metodo para incrementar los niveles de biodisponibilidad o reducir su variabilidad
WO2006007354A3 (en) A drug/polymer complex, preferably ciprofloxacin/hpmc, its method of manufacturing using lyophilization and its use in an osmotic device
ATE432063T1 (de) Verfahren zur herstellung von physiologisch aktiven substanzen enthaltenden dispersionen unter anwendung von hochdruck und hochscherkraft
DE50014164D1 (de) Verfahren zur herstellung einer wasserunlöslichen amorphen retardmatrix
CN107296822A (zh) 一种中药难溶性有效成分的固体分散体及其制备方法
ATE289801T1 (de) Verabreichungssystem für wasserunlösliche arzneistoffe
KR960028917A (ko) 경구투여용 사이클로스포린 에이 고체미셀분산체, 이의 제조 방법 및 고형제제
DE60000286T2 (de) Lipide enthaltende sojaextrakte, verfahren zu deren herstellung und pharmazeutische und kosmetische zusammensetzung
ATE355069T1 (de) Verfahren zur herstellung polyvalenter bakteriophagenpräparationen zur behandlung bakterieller infektionen
DE602004030131D1 (de) Mahonia aquifolium extrakt, extraktionsverfahren und diesen enthaltende pharmazeutische zusammensetzung
WO2001028589A3 (de) Formkörper mit amphiphilen äusseren phase und lipophilen inneren phase
MXPA02009056A (es) Proceso para la preparacion de formulaciones de liberacion acelerada usando fluidos comprimidos.

Legal Events

Date Code Title Description
8364 No opposition during term of opposition