ATE355362T1 - Verfahren zur induzierung der osteoblastischen differenzierung der zellen des menschlichen extramedullären fettgewebes - Google Patents

Verfahren zur induzierung der osteoblastischen differenzierung der zellen des menschlichen extramedullären fettgewebes

Info

Publication number
ATE355362T1
ATE355362T1 AT98955664T AT98955664T ATE355362T1 AT E355362 T1 ATE355362 T1 AT E355362T1 AT 98955664 T AT98955664 T AT 98955664T AT 98955664 T AT98955664 T AT 98955664T AT E355362 T1 ATE355362 T1 AT E355362T1
Authority
AT
Austria
Prior art keywords
cells
adiotive
tissue cells
osteoblastic differentiation
human extramedullary
Prior art date
Application number
AT98955664T
Other languages
English (en)
Inventor
Jean-Louis Patat
Jean Darondel
Jean-Pierre Ouhayoun
Alain Lecoeur
Original Assignee
Bio Holdings Int Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bio Holdings Int Ltd filed Critical Bio Holdings Int Ltd
Application granted granted Critical
Publication of ATE355362T1 publication Critical patent/ATE355362T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0654—Osteocytes, Osteoblasts, Odontocytes; Bones, Teeth
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/155—Bone morphogenic proteins [BMP]; Osteogenins; Osteogenic factor; Bone inducing factor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/30—Hormones
    • C12N2501/38—Hormones with nuclear receptors
    • C12N2501/39—Steroid hormones
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C12N2506/13—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells
    • C12N2506/1346—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells from mesenchymal stem cells
    • C12N2506/1384—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells from mesenchymal stem cells from adipose-derived stem cells [ADSC], from adipose stromal stem cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
AT98955664T 1997-11-14 1998-11-16 Verfahren zur induzierung der osteoblastischen differenzierung der zellen des menschlichen extramedullären fettgewebes ATE355362T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9714328A FR2771102B1 (fr) 1997-11-14 1997-11-14 Procede pour induire la differenciation osteoblastique de cellules de tissu adipeux extramedullaire humain

Publications (1)

Publication Number Publication Date
ATE355362T1 true ATE355362T1 (de) 2006-03-15

Family

ID=9513402

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98955664T ATE355362T1 (de) 1997-11-14 1998-11-16 Verfahren zur induzierung der osteoblastischen differenzierung der zellen des menschlichen extramedullären fettgewebes

Country Status (10)

Country Link
US (1) US6426222B1 (de)
EP (1) EP1029035B1 (de)
JP (1) JP3650734B2 (de)
AT (1) ATE355362T1 (de)
AU (1) AU752553B2 (de)
CA (1) CA2309907C (de)
DE (1) DE69837212T2 (de)
ES (1) ES2283078T3 (de)
FR (1) FR2771102B1 (de)
WO (1) WO1999025813A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1166773C (zh) * 1997-12-02 2004-09-15 泽恩比奥公司 分离的人脂肪组织衍生的基质细胞
KR100979664B1 (ko) * 1999-03-10 2010-09-02 유니버시티 오브 피츠버그 오브 더 커먼웰쓰 시스템 오브 하이어 에듀케이션 지방 유래 간세포 및 격자
FR2833270B1 (fr) * 2001-12-10 2004-02-27 Sympathos Modele de developpement osseux
EP1496978A4 (de) * 2002-04-03 2006-11-29 Artecel Sciences Inc Verbesserungen adipozytischer differenzierter adipositas-stammzellen von erwachsenen und ihre verwendung
US7531355B2 (en) * 2005-07-29 2009-05-12 The Regents Of The University Of California Methods and compositions for smooth muscle reconstruction
PL2101570T3 (pl) * 2006-12-14 2013-07-31 Teva Pharma Sól taninianu rasagiliny
US9650608B2 (en) 2013-02-22 2017-05-16 Medivet America, Llc Activating adipose-derived stem cells for transplantation

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5164187A (en) * 1990-04-05 1992-11-17 Norian Corporation Hydroxyapatite prosthesis coatings
US5300687A (en) * 1991-07-18 1994-04-05 Ortho Pharmaceutical Corporation Trifluoromethylbenzylphosphonates useful in treating osteoporosis
US5370692A (en) * 1992-08-14 1994-12-06 Guild Associates, Inc. Rapid, customized bone prosthesis
IT1282207B1 (it) * 1995-11-20 1998-03-16 Fidia Advanced Biopolymers Srl Sistemi di coltura di cellule staminali di midollo osseo umano in matrici tridimensionali costituiti da esteri dell'acido ialuronico
JP2000503542A (ja) * 1996-01-16 2000-03-28 デピュイ オーソピーディック，インコーポレイテッド 造血及び非造血組織からの前駆細胞の分離及び ｉｎ ｖｉｖｏ 骨及び軟骨再生におけるそれらの使用

Also Published As

Publication number Publication date
AU1242799A (en) 1999-06-07
CA2309907C (en) 2010-01-26
WO1999025813A1 (fr) 1999-05-27
JP3650734B2 (ja) 2005-05-25
EP1029035A1 (de) 2000-08-23
DE69837212T2 (de) 2007-11-22
US6426222B1 (en) 2002-07-30
DE69837212D1 (de) 2007-04-12
FR2771102B1 (fr) 2000-12-15
ES2283078T3 (es) 2007-10-16
EP1029035B1 (de) 2007-02-28
JP2001523447A (ja) 2001-11-27
FR2771102A1 (fr) 1999-05-21
CA2309907A1 (en) 1999-05-27
AU752553B2 (en) 2002-09-19

Similar Documents

Publication Publication Date Title
Li et al. Effects of flow shear stress and mass transport on the construction of a large-scale tissue-engineered bone in a perfusion bioreactor
Jagodzinski et al. Influence of perfusion and cyclic compression on proliferation and differentiation of bone marrow stromal cells in 3-dimensional culture
Kreke et al. Fluid flow stimulates expression of osteopontin and bone sialoprotein by bone marrow stromal cells in a temporally dependent manner
Tsai et al. Type I collagen promotes proliferation and osteogenesis of human mesenchymal stem cells via activation of ERK and Akt pathways
US4609551A (en) Process of and material for stimulating growth of cartilage and bony tissue at anatomical sites
Lim et al. In vitro effects of low‐intensity pulsed ultrasound stimulation on the osteogenic differentiation of human alveolar bone‐derived mesenchymal stem cells for tooth tissue engineering
RU2006145431A (ru) Композиция для репарации хрящевой и костной ткани
DE69534869D1 (de) Matrix für Gewebekultur, Verfahren zur Kultivierung von Gewebe, Verfahren zum Fixieren von kultiviertem Gewebe und fixierte Kunsthaut
Seruya et al. Clonal population of adult stem cells: life span and differentiation potential
AU1615599A (en) Differentiation of adipose stromal cells into osteoblasts and uses thereof
DE59709515D1 (de) Verfahren zur herstellung von wirkstoffhaltigen knochenzementen
WO2001068811A3 (de) Verfahren zur in vitro-herstellung von dreidimensionalem, vitalem knorpel- oder knochengewebe und dessen verwendung als transplantationsmaterial
Dimicco et al. Structure of pericellular matrix around agarose-embedded chondrocytes
ATE466072T1 (de) Bandscheibe
DE60009956D1 (de) Wachstumsfaktoren und l-glutamin enthaltendes zellkulturmedium
IL133428A (en) Hyaluronic acid derivative based cell culture and biodegradable three-dimensional matrix
Wu et al. Assessment of polyglycolic acid scaffolds for periodontal ligament regeneration
DE59912826D1 (de) Kulturvorrichtung und verfahren zur kultivierung von zellen oder gewebekomponenten
ATE355362T1 (de) Verfahren zur induzierung der osteoblastischen differenzierung der zellen des menschlichen extramedullären fettgewebes
DE69811220T2 (de) Zusammensetzungen zum konservieren von lebenden biologischen materialien und verfahren zu ihrer verwendung
DE50312433D1 (de) Gezüchtete knorpelzellen beinhaltendes implantat und verfahren zur herstellung
ATE283714T1 (de) Preadipozyten enthaltende biomaterialien zur regeneration von weichgewebe
DE69633393D1 (de) Mitteln zur behandlung von auto-immun krankheiten
ATE222122T1 (de) Verfahren zur tötung von zielzellen in geernteten zellpopulationen mit hilfe von zwei immunotoxinen
Bodhak et al. Combinatorial cassettes to systematically evaluate tissue-engineered constructs in recipient mice

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 1029035

Country of ref document: EP