ATE354576T1 - Neues, aus kulturfermentierungen isoliertes sordarinderivat und wirkungen als antipilzmittel - Google Patents
Neues, aus kulturfermentierungen isoliertes sordarinderivat und wirkungen als antipilzmittelInfo
- Publication number
- ATE354576T1 ATE354576T1 AT02786991T AT02786991T ATE354576T1 AT E354576 T1 ATE354576 T1 AT E354576T1 AT 02786991 T AT02786991 T AT 02786991T AT 02786991 T AT02786991 T AT 02786991T AT E354576 T1 ATE354576 T1 AT E354576T1
- Authority
- AT
- Austria
- Prior art keywords
- sordarine
- effects
- new
- antifungal agent
- derivative isolated
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/10—Spiro-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
- A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
- A61K31/7072—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid having two oxo groups directly attached to the pyrimidine ring, e.g. uridine, uridylic acid, thymidine, zidovudine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Oncology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Saccharide Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Fertilizers (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US34036701P | 2001-12-14 | 2001-12-14 |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE354576T1 true ATE354576T1 (de) | 2007-03-15 |
Family
ID=23333054
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT02786991T ATE354576T1 (de) | 2001-12-14 | 2002-12-10 | Neues, aus kulturfermentierungen isoliertes sordarinderivat und wirkungen als antipilzmittel |
Country Status (8)
Country | Link |
---|---|
US (1) | US20040242904A1 (de) |
EP (1) | EP1458725B1 (de) |
JP (1) | JP2005519039A (de) |
AT (1) | ATE354576T1 (de) |
AU (1) | AU2002351340A1 (de) |
CA (1) | CA2469879A1 (de) |
DE (1) | DE60218341D1 (de) |
WO (1) | WO2003051889A1 (de) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2010074101A1 (ja) * | 2008-12-25 | 2010-07-01 | 住友化学株式会社 | アミノピリジン化合物及びその用途 |
KR102526812B1 (ko) * | 2021-01-11 | 2023-04-27 | 고려대학교 산학협력단 | 모리니아펀진을 유효성분으로 포함하는 식물병 방제용 조성물 |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3146899A1 (de) * | 1981-11-26 | 1983-06-01 | Boehringer Mannheim Gmbh, 6800 Mannheim | Neue ketale von 3'''-dehydro-cardenolid-tridigitoxosiden, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
DE3431195A1 (de) * | 1984-08-24 | 1986-03-06 | Troponwerke GmbH & Co KG, 5000 Köln | Neue benzodiazepine, verfahren zu ihrer herstellung sowie ihre verwendung |
EP0711783A1 (de) * | 1994-11-08 | 1996-05-15 | Glaxo, S.A. | Antifungale Sordarinderivate |
US5854280A (en) * | 1994-11-08 | 1998-12-29 | Glaxo Wellcome S.A. | Antifungal sordaridin derivatives |
US6069126A (en) * | 1996-09-12 | 2000-05-30 | Merck & Co., Inc. | Antifungal combination therapy |
US6436395B1 (en) * | 1996-09-18 | 2002-08-20 | Merck & Co., Inc. | Rosellinia subiculata ATCC 74386 and fungus ATCC 74387 for producing sordarin compounds for fungi control |
US6040463A (en) * | 1996-10-07 | 2000-03-21 | Merck & Co., Inc. | Sordarin derivatives |
US5965612A (en) * | 1997-08-22 | 1999-10-12 | Merck & Co., Inc. | 4-cyano-4-deformylsordaricin derivatives |
US5972996A (en) * | 1997-08-22 | 1999-10-26 | Merck & Co., Inc. | 4-cyano-4-deformylsordarin derivatives |
US6136853A (en) * | 1997-10-03 | 2000-10-24 | Merck & Co., Inc. | Sordarin derivatives |
AU760975B2 (en) * | 1998-10-26 | 2003-05-22 | Merck & Co., Inc. | Microbial transformation product |
-
2002
- 2002-12-10 DE DE60218341T patent/DE60218341D1/de not_active Expired - Lifetime
- 2002-12-10 CA CA002469879A patent/CA2469879A1/en not_active Abandoned
- 2002-12-10 US US10/497,370 patent/US20040242904A1/en not_active Abandoned
- 2002-12-10 AT AT02786991T patent/ATE354576T1/de not_active IP Right Cessation
- 2002-12-10 JP JP2003552771A patent/JP2005519039A/ja not_active Withdrawn
- 2002-12-10 AU AU2002351340A patent/AU2002351340A1/en not_active Abandoned
- 2002-12-10 WO PCT/US2002/039411 patent/WO2003051889A1/en active IP Right Grant
- 2002-12-10 EP EP02786991A patent/EP1458725B1/de not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
EP1458725A4 (de) | 2005-09-07 |
EP1458725B1 (de) | 2007-02-21 |
DE60218341D1 (de) | 2007-04-05 |
WO2003051889A1 (en) | 2003-06-26 |
EP1458725A1 (de) | 2004-09-22 |
AU2002351340A1 (en) | 2003-06-30 |
US20040242904A1 (en) | 2004-12-02 |
CA2469879A1 (en) | 2003-06-26 |
JP2005519039A (ja) | 2005-06-30 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |