ATE196290T1 - Pyridin- und pyrazindicarbonsäurederivate als zellwachstumsregulatoren - Google Patents
Pyridin- und pyrazindicarbonsäurederivate als zellwachstumsregulatorenInfo
- Publication number
- ATE196290T1 ATE196290T1 AT95941202T AT95941202T ATE196290T1 AT E196290 T1 ATE196290 T1 AT E196290T1 AT 95941202 T AT95941202 T AT 95941202T AT 95941202 T AT95941202 T AT 95941202T AT E196290 T1 ATE196290 T1 AT E196290T1
- Authority
- AT
- Austria
- Prior art keywords
- pyrazinecarbonic
- pyridine
- cell growth
- acid derivatives
- growth regulators
- Prior art date
Links
- JUJWROOIHBZHMG-UHFFFAOYSA-N Pyridine Chemical compound C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 title 2
- 239000002253 acid Substances 0.000 title 1
- 230000010261 cell growth Effects 0.000 title 1
- 239000003630 growth substance Substances 0.000 title 1
- UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Natural products COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 title 1
- 208000031888 Mycoses Diseases 0.000 abstract 1
- 230000001580 bacterial effect Effects 0.000 abstract 1
- 150000003216 pyrazines Chemical class 0.000 abstract 1
- 230000000638 stimulation Effects 0.000 abstract 1
- 230000003612 virological effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
- C07D213/82—Amides; Imides in position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D241/24—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9425730.0A GB9425730D0 (en) | 1994-12-20 | 1994-12-20 | Compounds |
| PCT/GB1995/002977 WO1996019457A1 (en) | 1994-12-20 | 1995-12-20 | Pyridine and pyrazinedicarboxylic-acid derivatives as cell proliferation regulators |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE196290T1 true ATE196290T1 (de) | 2000-09-15 |
Family
ID=10766245
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT95941202T ATE196290T1 (de) | 1994-12-20 | 1995-12-20 | Pyridin- und pyrazindicarbonsäurederivate als zellwachstumsregulatoren |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US5972926A (de) |
| EP (1) | EP0799208B1 (de) |
| AT (1) | ATE196290T1 (de) |
| AU (1) | AU4268696A (de) |
| DE (1) | DE69518857T2 (de) |
| ES (1) | ES2150021T3 (de) |
| GB (1) | GB9425730D0 (de) |
| WO (1) | WO1996019457A1 (de) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9425730D0 (en) * | 1994-12-20 | 1995-02-22 | Nycomed Pharma As | Compounds |
| JP2001509795A (ja) * | 1997-01-27 | 2001-07-24 | ニィコメド・オーストリア・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング | 血液調節作用を有する新規化合物 |
| US6184241B1 (en) * | 1998-08-24 | 2001-02-06 | Kansas State University Research Foundation | Aspartic protease inhibitors |
| US6989379B1 (en) | 1999-04-22 | 2006-01-24 | H. Lundbick A/S | Selective NPY (Y5) antagonists |
| US6218408B1 (en) | 1999-06-30 | 2001-04-17 | Synaptic Pharmaceutical Corporation | Selective NPY (Y5) antagonists (bicyclics) |
| US6340683B1 (en) | 1999-04-22 | 2002-01-22 | Synaptic Pharmaceutical Corporation | Selective NPY (Y5) antagonists (triazines) |
| PT1183245E (pt) | 1999-04-22 | 2007-07-12 | Lundbeck & Co As H | Antagonistas selectivos de npy (y5) |
| US6222040B1 (en) | 1999-06-30 | 2001-04-24 | Synaptic Pharmaceutical Corporation | Selective NPY (Y5) antagonists (tricyclics) |
| US6214853B1 (en) | 1999-06-30 | 2001-04-10 | Synaptic Pharmaceutical Corporation | Selective NPY (Y5) antagonists (bicyclics) |
| US6225330B1 (en) | 1999-06-30 | 2001-05-01 | Synaptic Pharmaceutical Corporation | Selective NPY (Y5) antagonists (tricyclics) |
| US7273880B2 (en) | 1999-06-30 | 2007-09-25 | H. Lunbeck A/S | Selective NPY (Y5) antagonists |
| FR2843590B1 (fr) | 2002-08-14 | 2007-10-05 | Prestwick Scient Capital Inc | Derives de l'acide r(+)-2-amino-3-hydroxypropanoique a action glycinergique |
| JP2008543953A (ja) * | 2006-04-20 | 2008-12-04 | テバ ファーマシューティカル インダストリーズ リミティド | エスゾピクロン結晶形態ａ、実質的に純粋なエスゾピクロン及び光学的に豊富なエスゾピクロンを調製するための方法 |
| WO2008002629A1 (en) * | 2006-06-26 | 2008-01-03 | Teva Pharmaceutical Industries Ltd. | Process for the preparation of zopiclone |
| US20080287447A1 (en) * | 2007-01-31 | 2008-11-20 | Nina Finkelstein | Methods for preparing eszopiclone |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL104323A0 (en) * | 1992-01-10 | 1993-05-13 | Smithkline Beecham Corp | Hemoregulatory peptides |
| GB9211677D0 (en) * | 1992-06-02 | 1992-07-15 | Nycomed Bioreg As | Peptide compounds |
| GB9211668D0 (en) * | 1992-06-02 | 1992-07-15 | Nycomed Bioreg As | Peptide compounds |
| GB9314200D0 (en) * | 1993-07-09 | 1993-08-18 | Hafslund Nycomed As | Peptide compounds |
| EP0725651B1 (de) * | 1993-10-29 | 1999-08-11 | Smithkline Beecham Corporation | Blutregulierende peptide |
| GB9324691D0 (en) * | 1993-12-01 | 1994-01-19 | Hafslund Nycomed As | Peptide compounds |
| GB9425730D0 (en) * | 1994-12-20 | 1995-02-22 | Nycomed Pharma As | Compounds |
-
1994
- 1994-12-20 GB GBGB9425730.0A patent/GB9425730D0/en active Pending
-
1995
- 1995-12-20 AT AT95941202T patent/ATE196290T1/de active
- 1995-12-20 US US08/849,456 patent/US5972926A/en not_active Expired - Fee Related
- 1995-12-20 DE DE69518857T patent/DE69518857T2/de not_active Expired - Lifetime
- 1995-12-20 AU AU42686/96A patent/AU4268696A/en not_active Abandoned
- 1995-12-20 EP EP95941202A patent/EP0799208B1/de not_active Expired - Lifetime
- 1995-12-20 ES ES95941202T patent/ES2150021T3/es not_active Expired - Lifetime
- 1995-12-20 WO PCT/GB1995/002977 patent/WO1996019457A1/en not_active Ceased
-
1999
- 1999-08-20 US US09/377,776 patent/US6124298A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| GB9425730D0 (en) | 1995-02-22 |
| DE69518857T2 (de) | 2001-04-26 |
| EP0799208B1 (de) | 2000-09-13 |
| DE69518857D1 (de) | 2000-10-19 |
| ES2150021T3 (es) | 2000-11-16 |
| WO1996019457A1 (en) | 1996-06-27 |
| US5972926A (en) | 1999-10-26 |
| AU4268696A (en) | 1996-07-10 |
| EP0799208A1 (de) | 1997-10-08 |
| US6124298A (en) | 2000-09-26 |
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