ATE354173T1 - Verfahren und vorrichtung zur bestimmung von reaktionsraten in flüssigkeiten mittels massenspektrometrie - Google Patents

Verfahren und vorrichtung zur bestimmung von reaktionsraten in flüssigkeiten mittels massenspektrometrie

Info

Publication number
ATE354173T1
ATE354173T1 AT98958132T AT98958132T ATE354173T1 AT E354173 T1 ATE354173 T1 AT E354173T1 AT 98958132 T AT98958132 T AT 98958132T AT 98958132 T AT98958132 T AT 98958132T AT E354173 T1 ATE354173 T1 AT E354173T1
Authority
AT
Austria
Prior art keywords
determined
reactants
reaction time
reaction
liquids
Prior art date
Application number
AT98958132T
Other languages
German (de)
English (en)
Inventor
Donald J Douglas
Lars Konermann
Bruce Collings
Original Assignee
Univ British Columbia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ British Columbia filed Critical Univ British Columbia
Application granted granted Critical
Publication of ATE354173T1 publication Critical patent/ATE354173T1/de

Links

Classifications

    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/02—Details
    • H01J49/04—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components
    • H01J49/0431—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components for liquid samples
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/08—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a stream of discrete samples flowing along a tube system, e.g. flow injection analysis
    • G01N35/085—Flow Injection Analysis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Electron Tubes For Measurement (AREA)
AT98958132T 1997-12-05 1998-12-03 Verfahren und vorrichtung zur bestimmung von reaktionsraten in flüssigkeiten mittels massenspektrometrie ATE354173T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/986,140 US6054709A (en) 1997-12-05 1997-12-05 Method and apparatus for determining the rates of reactions in liquids by mass spectrometry

Publications (1)

Publication Number Publication Date
ATE354173T1 true ATE354173T1 (de) 2007-03-15

Family

ID=25532120

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98958132T ATE354173T1 (de) 1997-12-05 1998-12-03 Verfahren und vorrichtung zur bestimmung von reaktionsraten in flüssigkeiten mittels massenspektrometrie

Country Status (8)

Country Link
US (1) US6054709A (https=)
EP (1) EP1036404B1 (https=)
JP (1) JP2001526398A (https=)
AT (1) ATE354173T1 (https=)
AU (1) AU1431099A (https=)
CA (1) CA2312891A1 (https=)
DE (1) DE69837106T2 (https=)
WO (1) WO1999030349A1 (https=)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6350987B1 (en) * 1998-03-31 2002-02-26 Dexter B. Northrup Enzymatic reaction mechanisms by quenched-flow mass spectrometry
US6630664B1 (en) * 1999-02-09 2003-10-07 Syagen Technology Atmospheric pressure photoionizer for mass spectrometry
JP4527353B2 (ja) * 2000-10-23 2010-08-18 サイモン フレーザー ユニバーシティー 個別液滴を生成する方法及び機器
JP4586275B2 (ja) * 2001-01-17 2010-11-24 味の素株式会社 複合体の界面を同定する方法
CA2387316A1 (en) * 2002-05-31 2003-11-30 The University Of Western Ontario Method and apparatus for the detection of noncovalent interactions by mass spectrometry - based diffusion measurements
US20060228696A1 (en) * 2002-06-27 2006-10-12 Robert Rohwer Methods for detecting and inactivating a prion
WO2004038752A2 (en) * 2002-10-21 2004-05-06 The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Contiguous capillary electrospray sources and analytical device
US20090068640A1 (en) * 2003-06-27 2009-03-12 Robert Rohwer Methods for detecting and inactivating a prion
JP3787578B2 (ja) * 2003-10-29 2006-06-21 アイダエンジニアリング株式会社 マイクロチップの微細流路における液体送液方法
US6870154B1 (en) 2004-02-27 2005-03-22 The University Of Western Ontario Capillary mixer with adjustable reaction chamber volume for mass spectrometry
WO2011146425A1 (en) * 2010-05-17 2011-11-24 Ohio University Microsecond time-resolved mass spectrometry
GB201019337D0 (en) * 2010-11-16 2010-12-29 Micromass Ltd Controlling hydrogen-deuterium exchange on a spectrum by spectrum basis
CN104737025B (zh) 2012-07-07 2018-02-27 建奥迪斯有限公司 用于生物化学传感器的流动管道系统
CN105164783A (zh) * 2013-04-30 2015-12-16 佳能株式会社 液滴喷射装置和离子源
WO2015019159A1 (en) * 2013-08-07 2015-02-12 Dh Technologies Development Pte. Ltd. Bubble removal from liquid flow into a mass spectrometer source
CN106683973A (zh) * 2017-01-17 2017-05-17 中国科学技术大学 一种用于质谱仪的电喷雾电离源装置及系统
JP7064746B2 (ja) * 2018-02-14 2022-05-11 国立大学法人浜松医科大学 イオン化装置、イオン化方法、プログラム、及び分析システム
US20220250102A1 (en) * 2019-07-31 2022-08-11 National Institute Of Advanced Industrial Science And Technology Spray ionization device, analysis device, and surface coating device

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5009849A (en) * 1984-12-14 1991-04-23 Monsanto Company Apparatus for carrying out catalyzed chemical reactions and for studying catalysis
DE3672710D1 (de) * 1985-08-21 1990-08-23 Kratos Analytical Ltd Vorrichtung und verfahren zum gebrauch bei der massenanalyse von chemischen proben.
US4861988A (en) * 1987-09-30 1989-08-29 Cornell Research Foundation, Inc. Ion spray apparatus and method
US4935624A (en) * 1987-09-30 1990-06-19 Cornell Research Foundation, Inc. Thermal-assisted electrospray interface (TAESI) for LC/MS
US5245186A (en) * 1991-11-18 1993-09-14 The Rockefeller University Electrospray ion source for mass spectrometry
US5608217A (en) * 1994-03-10 1997-03-04 Bruker-Franzen Analytik Gmbh Electrospraying method for mass spectrometric analysis
DE4415480C2 (de) * 1994-05-02 1999-09-02 Bruker Daltonik Gmbh Vorrichtung und Verfahren zur massenspektrometrischen Untersuchung von Substanzgemischen durch Kopplung kapillarelektrophoretischer Separation (CE) mit Elektrospray-Ionisierung (ESI)

Also Published As

Publication number Publication date
US6054709A (en) 2000-04-25
DE69837106T2 (de) 2007-08-30
AU1431099A (en) 1999-06-28
EP1036404A1 (en) 2000-09-20
JP2001526398A (ja) 2001-12-18
EP1036404B1 (en) 2007-02-14
CA2312891A1 (en) 1999-06-17
DE69837106D1 (de) 2007-03-29
WO1999030349A1 (en) 1999-06-17

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