ATE348336T1 - Mikrokavitätsbiosensor, herstellungsverfahren und verwendungen davon - Google Patents

Mikrokavitätsbiosensor, herstellungsverfahren und verwendungen davon

Info

Publication number
ATE348336T1
ATE348336T1 AT02706399T AT02706399T ATE348336T1 AT E348336 T1 ATE348336 T1 AT E348336T1 AT 02706399 T AT02706399 T AT 02706399T AT 02706399 T AT02706399 T AT 02706399T AT E348336 T1 ATE348336 T1 AT E348336T1
Authority
AT
Austria
Prior art keywords
biological sensor
probes
production method
methods
binding
Prior art date
Application number
AT02706399T
Other languages
English (en)
Inventor
Selena Chan
Phillipe M Fauchet
Scott R Horner
Benjamin L Miller
Original Assignee
Univ Rochester
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Rochester filed Critical Univ Rochester
Application granted granted Critical
Publication of ATE348336T1 publication Critical patent/ATE348336T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/551—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being inorganic
    • G01N33/552—Glass or silica
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C12Q1/6825—Nucleic acid detection involving sensors

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Inorganic Chemistry (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Cosmetics (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
AT02706399T 2001-02-21 2002-02-21 Mikrokavitätsbiosensor, herstellungsverfahren und verwendungen davon ATE348336T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US27052701P 2001-02-21 2001-02-21

Publications (1)

Publication Number Publication Date
ATE348336T1 true ATE348336T1 (de) 2007-01-15

Family

ID=23031652

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02706399T ATE348336T1 (de) 2001-02-21 2002-02-21 Mikrokavitätsbiosensor, herstellungsverfahren und verwendungen davon

Country Status (5)

Country Link
US (1) US7226733B2 (de)
EP (1) EP1373894B1 (de)
AT (1) ATE348336T1 (de)
DE (1) DE60216735D1 (de)
WO (1) WO2002068957A1 (de)

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WO2004111612A2 (en) 2003-03-05 2004-12-23 The Regents Of The University Of California Porous nanostructures and methods involving the same
US7266284B2 (en) * 2003-04-17 2007-09-04 University Of Rochester Method for controlling one or more temperature dependent optical properties of a structure and a system and product thereof
US7444045B2 (en) * 2003-10-14 2008-10-28 3M Innovative Properties Company Hybrid sphere-waveguide resonators
US7259855B2 (en) * 2003-10-14 2007-08-21 3M Innovative Properties Company Porous microsphere resonators
WO2005081707A2 (en) 2003-11-20 2005-09-09 Biowarn, Llc Methodology and apparatus for the detection of biological substances
JP4374447B2 (ja) * 2003-12-25 2009-12-02 独立行政法人産業技術総合研究所 タンパク質と糖鎖との相互作用を分析する方法
US7271896B2 (en) * 2003-12-29 2007-09-18 Intel Corporation Detection of biomolecules using porous biosensors and raman spectroscopy
US20070184222A1 (en) * 2004-04-20 2007-08-09 University Of Rochester Hydrogel-supported porous semiconductor devices
US7352933B2 (en) * 2004-05-27 2008-04-01 3M Innovative Properties Company Dielectric microcavity sensors
US7271379B2 (en) * 2004-05-27 2007-09-18 3M Innovative Properties Company Dielectric microcavity fluorosensors excited with a broadband light source
US7257279B2 (en) * 2004-09-20 2007-08-14 3M Innovative Properties Company Systems and methods for biosensing and microresonator sensors for same
WO2006044957A2 (en) * 2004-10-19 2006-04-27 The Regents Of The University Of California Porous photonic crystal with light scattering domains and methods of synthesis and use thereof
US7875426B2 (en) * 2005-02-04 2011-01-25 University Of South Florida DNA biochip and methods of use
US20060234391A1 (en) * 2005-02-18 2006-10-19 University Of Rochester Optical sensor based on resonant porous silicon structures
US20070108465A1 (en) * 2005-03-10 2007-05-17 The Regents Of The University Of California Porous microstructure multi layer spectroscopy and biosensing
US20060276047A1 (en) * 2005-03-14 2006-12-07 University Of Rochester Macroporous silicon microcavity with tunable pore size
JP2009543023A (ja) * 2005-07-18 2009-12-03 コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ マルチレイヤ基板構造を用いた発光センサ
US7330252B2 (en) * 2005-12-30 2008-02-12 Intel Corporation Porous silicon on-chip spectroscopy system
WO2007082075A2 (en) * 2006-01-11 2007-07-19 The Regents Of The University Of California Optical sensor for detecting chemical reaction activity
EP1999247A4 (de) * 2006-03-14 2011-08-31 Univ Rochester Zellkulturvorrichtungen mit ultradünner poröser membran und anwendungen davon
ITTO20060213A1 (it) * 2006-03-21 2007-09-22 Consiglio Nazionale Ricerche Apparato per la determinazione del contenuto di etanolo in sostanze liquide o aeriformi e relativo procedimento
US7532790B2 (en) * 2006-03-29 2009-05-12 3M Innovative Properties Company Method of coupling light into microresonators
US7389025B2 (en) * 2006-03-29 2008-06-17 3M Innovative Properties Company Coupling light into microresonators
WO2008034070A2 (en) 2006-09-15 2008-03-20 Pathologics Associates, Inc. Improved method for biomolecular detection and system thereof
US20100279886A1 (en) * 2007-04-03 2010-11-04 University Of Rochester Two-dimensional photonic bandgap structures for ultrahigh-sensitivity biosensing
WO2009020682A2 (en) 2007-05-08 2009-02-12 The Trustees Of Boston University Chemical functionalization of solid-state nanopores and nanopore arrays and applications thereof
EP2185480A4 (de) * 2007-07-30 2010-09-08 Trex Entpr Corp Verfahren zur chemischen behandlung von porösen siliciumoberflächen
US8702640B2 (en) 2007-08-17 2014-04-22 The Invention Science Fund I, Llc System, devices, and methods including catheters configured to monitor and inhibit biofilm formation
US8734718B2 (en) 2007-08-17 2014-05-27 The Invention Science Fund I, Llc Systems, devices, and methods including catheters having an actively controllable therapeutic agent delivery component
US8706211B2 (en) 2007-08-17 2014-04-22 The Invention Science Fund I, Llc Systems, devices, and methods including catheters having self-cleaning surfaces
US8647292B2 (en) 2007-08-17 2014-02-11 The Invention Science Fund I, Llc Systems, devices, and methods including catheters having components that are actively controllable between two or more wettability states
US8366652B2 (en) 2007-08-17 2013-02-05 The Invention Science Fund I, Llc Systems, devices, and methods including infection-fighting and monitoring shunts
US8753304B2 (en) 2007-08-17 2014-06-17 The Invention Science Fund I, Llc Systems, devices, and methods including catheters having acoustically actuatable waveguide components for delivering a sterilizing stimulus to a region proximate a surface of the catheter
US8192600B2 (en) 2007-09-27 2012-06-05 The Board Of Trustees Of The University Of Illinois Solid state device
US8092855B2 (en) * 2007-11-28 2012-01-10 California Institute Of Technology Click chemistry surface functionalization for resonant micro-cavity sensors
US8003403B1 (en) 2008-03-19 2011-08-23 Emitech, Inc Optochemical sensors for the detection of low pressure vapors based on porous semiconductors and emissive organics
US8697437B1 (en) 2008-08-29 2014-04-15 University Of South Florida Magnetic metabolite and diagnostic transfer disks
US8506887B2 (en) * 2008-10-17 2013-08-13 Vanderbilt University Porous membrane waveguide sensors and sensing systems therefrom for detecting biological or chemical targets
US8585627B2 (en) 2008-12-04 2013-11-19 The Invention Science Fund I, Llc Systems, devices, and methods including catheters configured to monitor biofilm formation having biofilm spectral information configured as a data structure
US20110295088A1 (en) 2008-12-04 2011-12-01 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Systems, devices, and methods including implantable devices with anti-microbial properties
EP2384168B1 (de) 2008-12-04 2014-10-08 Searete LLC Aktiv kontrollierbare sterilisierende erregungsabgabe-implantate
CA2706063A1 (en) * 2009-05-29 2010-11-29 Vanderbilt University Diffraction gratings comprising porous materials and diffraction-based sensors comprising porous materials
US20100328646A1 (en) * 2009-06-26 2010-12-30 Emitech, Inc. Optical nanoporous sensors for detection of water based vapors and their leakage from sealed containers
US9007593B2 (en) 2010-07-20 2015-04-14 The Regents Of The University Of California Temperature response sensing and classification of analytes with porous optical films
CA2811600A1 (en) 2010-09-20 2012-03-29 Vanderbilt University Nanoscale porous gold film sers template
EP2487490A1 (de) * 2011-02-11 2012-08-15 FZMB GmbH Forschungszentrum für Medizintechnik und Biotechnologie Heterogener Bindungsassay mit verbesserter optischer Auswertbarkeit oder poröse Festphase für Bindungsassays mit verbesserter optischer Auswertbarkeit
CN102809498A (zh) * 2012-07-20 2012-12-05 浙江大学 一种低丰度低分子量蛋白富集材料的制备方法
US9889504B2 (en) 2012-12-11 2018-02-13 Vanderbilt University Porous nanomaterials having three-dimensional patterning
WO2014155381A1 (en) 2013-03-25 2014-10-02 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Method and apparatus for bacterial monitoring
US10215753B2 (en) 2013-08-05 2019-02-26 University Of Rochester Method for the topographically-selective passivation of micro- and nanoscale devices
US10209254B2 (en) 2013-10-09 2019-02-19 University Of Rochester Chips, detection systems, and methods for multiplex pneumococcus serology
CN104406936B (zh) * 2014-11-17 2017-03-15 新疆大学 一种基于多孔硅的阵列生物芯片及其制备方法和应用
US10656085B2 (en) 2015-04-08 2020-05-19 Bactusense Technologies Ltd. High sensitivity real-time bacterial monitor
WO2017161224A1 (en) * 2016-03-18 2017-09-21 Massachusetts Institute Of Technology Nanoporous semiconductor materials and manufacture thereof
CN108387424B (zh) * 2018-02-27 2021-08-03 杭州汇健科技有限公司 一种用于生物样本预处理的多孔硅材料的制备方法及其应用
US11004943B2 (en) 2018-04-05 2021-05-11 Massachusetts Institute Of Technology Porous and nanoporous semiconductor materials and manufacture thereof
WO2020037307A1 (en) 2018-08-17 2020-02-20 University Of Rochester Optical biosensor comprising disposable diagnostic membrane and permanent photonic sensing device
CN111795948B (zh) * 2020-07-03 2022-04-19 西湖大学 光学生物传感器及covid-19病毒检测装置

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Also Published As

Publication number Publication date
DE60216735D1 (de) 2007-01-25
EP1373894A4 (de) 2004-04-21
US20020192680A1 (en) 2002-12-19
EP1373894A1 (de) 2004-01-02
US7226733B2 (en) 2007-06-05
EP1373894B1 (de) 2006-12-13
WO2002068957A1 (en) 2002-09-06

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