ATE348171T1 - Proteine mit lecithin-cholesterin acetyltransferase-ähnlicher aktivität, deren herstellung und verwendung - Google Patents
Proteine mit lecithin-cholesterin acetyltransferase-ähnlicher aktivität, deren herstellung und verwendungInfo
- Publication number
- ATE348171T1 ATE348171T1 AT98912745T AT98912745T ATE348171T1 AT E348171 T1 ATE348171 T1 AT E348171T1 AT 98912745 T AT98912745 T AT 98912745T AT 98912745 T AT98912745 T AT 98912745T AT E348171 T1 ATE348171 T1 AT E348171T1
- Authority
- AT
- Austria
- Prior art keywords
- protein
- salt
- partial peptide
- lecithin
- activity
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1025—Acyltransferases (2.3)
- C12N9/1029—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y203/00—Acyltransferases (2.3)
- C12Y203/01—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
- C12Y203/01043—Phosphatidylcholine-sterol O-acyltransferase (2.3.1.43), i.e. lecithin-cholesterol acyltransferase or LCAT
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2799/00—Uses of viruses
- C12N2799/02—Uses of viruses as vector
- C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
- Y10T436/104165—Lipid, cholesterol, or triglyceride standard or control
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP9335597 | 1997-04-11 | ||
JP18488597 | 1997-07-10 | ||
JP1028998 | 1998-01-22 |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE348171T1 true ATE348171T1 (de) | 2007-01-15 |
Family
ID=27278908
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT98912745T ATE348171T1 (de) | 1997-04-11 | 1998-04-09 | Proteine mit lecithin-cholesterin acetyltransferase-ähnlicher aktivität, deren herstellung und verwendung |
Country Status (8)
Country | Link |
---|---|
US (2) | US6498019B1 (de) |
EP (1) | EP0973914B1 (de) |
JP (1) | JP2008148708A (de) |
AT (1) | ATE348171T1 (de) |
AU (1) | AU6748198A (de) |
CA (1) | CA2284832A1 (de) |
DE (1) | DE69836626T2 (de) |
WO (1) | WO1998046767A1 (de) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20030104559A1 (en) * | 1998-03-27 | 2003-06-05 | Genentech, Inc. | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US6940003B1 (en) | 1998-12-03 | 2005-09-06 | E. I. Du Pont De Nemours And Company | Plan lecithin: cholesterol acyltransferases |
WO2000032791A2 (en) * | 1998-12-03 | 2000-06-08 | E.I. Du Pont De Nemours And Company | Plan lecithin:cholesterol acyltransferases |
US7462757B2 (en) * | 2001-05-22 | 2008-12-09 | Takeda Chemical Industries, Ltd. | Animal with gene hypoexpression |
WO2003062416A1 (fr) * | 2002-01-21 | 2003-07-31 | Takeda Chemical Industries, Ltd. | Procede de criblage d'agents preventifs et de remedes pour l'arteriosclerose |
AU2003221402A1 (en) * | 2002-03-18 | 2003-09-29 | Takeda Chemical Industries, Ltd. | Llpl gene and novel use of its gene product |
CA2787343C (en) * | 2006-06-26 | 2016-08-02 | Amgen Inc. | Compositions comprising modified lcat and uses thereof |
DK2489731T3 (en) | 2007-07-26 | 2014-11-17 | Amgen Inc | Modified lecithin-cholesterol acyltransferase enzymes |
EP2318036B1 (de) * | 2008-06-30 | 2015-06-03 | The Regents of the University of Michigan | Aktivität von lysosomaler phospholipase a2 (lpla2) als diagnostisches und therapeutisches target zur identifizierung und behandlung von systemischem lupus erythematodes |
GB2463925A (en) * | 2008-07-11 | 2010-04-07 | Eisai London Res Lab Ltd | Screening for agents for the treatment of Alzheimers Disease |
JP6174995B2 (ja) * | 2010-05-06 | 2017-08-02 | メディミューン,エルエルシー | コレステリルエステルのステロイド産生組織への送達 |
AU2012347540A1 (en) * | 2011-12-08 | 2014-06-26 | Amgen Inc. | Agonistic human LCAT antigen binding proteins and their use in therapy |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS51129293A (en) * | 1975-05-02 | 1976-11-10 | Nippon Shoji Kk | Measurement method of activity of lecithin cholesteral acyl transferas e |
US4163011A (en) * | 1978-08-28 | 1979-07-31 | Orts Richard J | Peptide compounds and compositions |
US5049488A (en) * | 1985-11-08 | 1991-09-17 | Genentech, Inc. | Method and nucleic acid for the preparation of lecithin:cholesterol acyltransferase |
JPH08176007A (ja) * | 1994-12-27 | 1996-07-09 | Snow Brand Milk Prod Co Ltd | 脂質代謝異常治療剤 |
FR2731710B1 (fr) * | 1995-03-14 | 1997-04-30 | Rhone Poulenc Rorer Sa | Virus recombinants exprimant la lecithine cholesterol acyltransferase et utilisations en therapie genique |
DE69636907T2 (de) * | 1995-11-09 | 2007-11-22 | The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Verwendung von lezithin-cholesterin-azetyltransferase für die behandlung von atherosklerose |
-
1998
- 1998-04-09 WO PCT/JP1998/001643 patent/WO1998046767A1/en active IP Right Grant
- 1998-04-09 CA CA002284832A patent/CA2284832A1/en not_active Abandoned
- 1998-04-09 US US09/402,532 patent/US6498019B1/en not_active Expired - Fee Related
- 1998-04-09 AT AT98912745T patent/ATE348171T1/de not_active IP Right Cessation
- 1998-04-09 DE DE69836626T patent/DE69836626T2/de not_active Expired - Lifetime
- 1998-04-09 AU AU67481/98A patent/AU6748198A/en not_active Abandoned
- 1998-04-09 EP EP98912745A patent/EP0973914B1/de not_active Expired - Lifetime
-
2002
- 2002-12-18 US US10/323,051 patent/US7157259B2/en not_active Expired - Fee Related
-
2007
- 2007-12-28 JP JP2007340674A patent/JP2008148708A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
CA2284832A1 (en) | 1998-10-22 |
DE69836626T2 (de) | 2007-04-05 |
AU6748198A (en) | 1998-11-11 |
US20030175905A1 (en) | 2003-09-18 |
US7157259B2 (en) | 2007-01-02 |
EP0973914A1 (de) | 2000-01-26 |
JP2008148708A (ja) | 2008-07-03 |
US6498019B1 (en) | 2002-12-24 |
DE69836626D1 (de) | 2007-01-25 |
EP0973914B1 (de) | 2006-12-13 |
WO1998046767A1 (en) | 1998-10-22 |
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Legal Events
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RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |