ATE335757T1 - Verfahren zur herstellung von lisinopril - Google Patents
Verfahren zur herstellung von lisinoprilInfo
- Publication number
- ATE335757T1 ATE335757T1 AT02744085T AT02744085T ATE335757T1 AT E335757 T1 ATE335757 T1 AT E335757T1 AT 02744085 T AT02744085 T AT 02744085T AT 02744085 T AT02744085 T AT 02744085T AT E335757 T1 ATE335757 T1 AT E335757T1
- Authority
- AT
- Austria
- Prior art keywords
- sup
- lisinopril
- lysine
- trifluoroacetyl
- derivative
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/022—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2
- C07K5/0222—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2 with the first amino acid being heterocyclic, e.g. Pro, Trp
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/TR2002/000023 WO2004000874A1 (en) | 2002-06-19 | 2002-06-19 | Process for the production of lisinopril |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE335757T1 true ATE335757T1 (de) | 2006-09-15 |
Family
ID=29997777
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT02744085T ATE335757T1 (de) | 2002-06-19 | 2002-06-19 | Verfahren zur herstellung von lisinopril |
Country Status (7)
Country | Link |
---|---|
US (1) | US20070093664A1 (de) |
EP (1) | EP1513868B1 (de) |
AT (1) | ATE335757T1 (de) |
AU (1) | AU2002345522A1 (de) |
DE (1) | DE60213880T2 (de) |
ES (1) | ES2269728T3 (de) |
WO (1) | WO2004000874A1 (de) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2008132759A2 (en) * | 2007-04-27 | 2008-11-06 | Matrix Laboratories Ltd | Industrially advantageous process for the production of lisinopril dihydrate |
CN104045687B (zh) * | 2014-05-21 | 2016-08-24 | 丽珠医药集团股份有限公司 | 一种赖诺普利的提纯方法 |
CN106699592B (zh) * | 2016-11-17 | 2020-12-08 | 浙江华海药业股份有限公司 | 一种制备赖诺普利中间体的方法 |
CN109422797B (zh) * | 2017-08-30 | 2023-12-19 | 上海科胜药物研发有限公司 | 一种赖诺普利中间体的制备方法 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL58849A (en) * | 1978-12-11 | 1983-03-31 | Merck & Co Inc | Carboxyalkyl dipeptides and derivatives thereof,their preparation and pharmaceutical compositions containing them |
US4925969A (en) * | 1985-02-04 | 1990-05-15 | Kanegafuchi Kagaku Kogyo Kabushiki Kaisha | Process for preparing ethyl-alpha-amino-gamma-oxo-gamma-phenybutyrate derivatives |
US5227497A (en) * | 1988-04-04 | 1993-07-13 | Kanegafuchi Kagaku Kogyo Kabushiki Kaisha | Process for preparing N2 -(1-carboxy-3-phenylpropyl)-L-lysine derivative |
JP3792777B2 (ja) * | 1996-05-10 | 2006-07-05 | 株式会社カネカ | 1−アルコキシカルボニル−3−フェニルプロピル誘導体の製造方法 |
IT1307265B1 (it) * | 1999-08-09 | 2001-10-30 | P F C Italiana Srl Speciality | Procedimento per la preparazione di prodotti intermedi nella sintesidi lisinopril. |
-
2002
- 2002-06-19 EP EP02744085A patent/EP1513868B1/de not_active Expired - Lifetime
- 2002-06-19 WO PCT/TR2002/000023 patent/WO2004000874A1/en active IP Right Grant
- 2002-06-19 AU AU2002345522A patent/AU2002345522A1/en not_active Abandoned
- 2002-06-19 AT AT02744085T patent/ATE335757T1/de not_active IP Right Cessation
- 2002-06-19 DE DE60213880T patent/DE60213880T2/de not_active Expired - Fee Related
- 2002-06-19 ES ES02744085T patent/ES2269728T3/es not_active Expired - Lifetime
- 2002-06-19 US US10/514,570 patent/US20070093664A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
EP1513868B1 (de) | 2006-08-09 |
ES2269728T3 (es) | 2007-04-01 |
AU2002345522A1 (en) | 2004-01-06 |
EP1513868A1 (de) | 2005-03-16 |
WO2004000874A1 (en) | 2003-12-31 |
DE60213880T2 (de) | 2007-01-18 |
DE60213880D1 (de) | 2006-09-21 |
US20070093664A1 (en) | 2007-04-26 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |