ATE334699T1 - Photosensitize funktionalisierte nanopartikel - Google Patents

Photosensitize funktionalisierte nanopartikel

Info

Publication number
ATE334699T1
ATE334699T1 AT02774962T AT02774962T ATE334699T1 AT E334699 T1 ATE334699 T1 AT E334699T1 AT 02774962 T AT02774962 T AT 02774962T AT 02774962 T AT02774962 T AT 02774962T AT E334699 T1 ATE334699 T1 AT E334699T1
Authority
AT
Austria
Prior art keywords
monolayer
metallic
nanoparticle
nanoparticles
functionalized
Prior art date
Application number
AT02774962T
Other languages
English (en)
Inventor
David Andrew Russell
Duncan Christopher Hone
Original Assignee
Cancer Rec Tech Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cancer Rec Tech Ltd filed Critical Cancer Rec Tech Ltd
Application granted granted Critical
Publication of ATE334699T1 publication Critical patent/ATE334699T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • A61K33/38Silver; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • A61K33/242Gold; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • A61K33/243Platinum; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • A61K33/26Iron; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • A61K33/34Copper; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • A61K41/0071PDT with porphyrins having exactly 20 ring atoms, i.e. based on the non-expanded tetrapyrrolic ring system, e.g. bacteriochlorin, chlorin-e6, or phthalocyanines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6921Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a particulate, a powder, an adsorbate, a bead or a sphere
    • A61K47/6923Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a particulate, a powder, an adsorbate, a bead or a sphere the form being an inorganic particle, e.g. ceramic particles, silica particles, ferrite or synsorb
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6921Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a particulate, a powder, an adsorbate, a bead or a sphere
    • A61K47/6927Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a particulate, a powder, an adsorbate, a bead or a sphere the form being a solid microparticle having no hollow or gas-filled cores
    • A61K47/6929Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a particulate, a powder, an adsorbate, a bead or a sphere the form being a solid microparticle having no hollow or gas-filled cores the form being a nanoparticle, e.g. an immuno-nanoparticle
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y30/00Nanotechnology for materials or surface science, e.g. nanocomposites
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00Nanotechnology
    • Y10S977/70Nanostructure
    • Y10S977/773Nanoparticle, i.e. structure having three dimensions of 100 nm or less
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00Nanotechnology
    • Y10S977/902Specified use of nanostructure
    • Y10S977/904Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00Nanotechnology
    • Y10S977/902Specified use of nanostructure
    • Y10S977/904Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
    • Y10S977/908Mechanical repair performed/surgical
    • Y10S977/911Cancer cell destruction

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Nanotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Materials Engineering (AREA)
  • Ceramic Engineering (AREA)
  • Condensed Matter Physics & Semiconductors (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Composite Materials (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Inorganic Compounds Of Heavy Metals (AREA)
  • Luminescent Compositions (AREA)
  • Steroid Compounds (AREA)
  • Light Receiving Elements (AREA)
  • Polymerisation Methods In General (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
AT02774962T 2001-11-01 2002-10-31 Photosensitize funktionalisierte nanopartikel ATE334699T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0126236.9A GB0126236D0 (en) 2001-11-01 2001-11-01 Photosensitiser functionalised nanoparticles

Publications (1)

Publication Number Publication Date
ATE334699T1 true ATE334699T1 (de) 2006-08-15

Family

ID=9924949

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02774962T ATE334699T1 (de) 2001-11-01 2002-10-31 Photosensitize funktionalisierte nanopartikel

Country Status (9)

Country Link
US (1) US7563818B2 (de)
EP (1) EP1455828B1 (de)
AT (1) ATE334699T1 (de)
AU (1) AU2002341159A1 (de)
CA (1) CA2465401A1 (de)
DE (1) DE60213655T2 (de)
ES (1) ES2268100T3 (de)
GB (1) GB0126236D0 (de)
WO (1) WO2003037297A2 (de)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007004033A2 (en) * 2005-07-01 2007-01-11 National University Of Singapore An electrically conductive composite
EP1779891A1 (de) * 2005-10-28 2007-05-02 Abdula Kurkayev Verfahren zum Aktivieren eines Photosensibilisators
US20070238660A1 (en) * 2006-03-31 2007-10-11 Stephen Michielsen Light activated antiviral materials and devices and methods for decontaminating virus infected environments
GB0712287D0 (en) 2007-06-22 2007-08-01 Ucl Business Plc Antimicrobial Conjugates
WO2008015445A2 (en) 2006-08-04 2008-02-07 Ucl Business Plc Computer devices and accessories
US20080181851A1 (en) * 2006-12-18 2008-07-31 Samira Guccione Photoacoustic contrast agents for molecular imaging
US9339485B2 (en) * 2007-03-02 2016-05-17 University Of Maryland, Baltimore County Plasmonic engineering of singlet oxygen and/or superoxide generation
US9358292B2 (en) 2007-04-08 2016-06-07 Immunolight, Llc Methods and systems for treating cell proliferation disorders
US8376013B2 (en) * 2008-03-11 2013-02-19 Duke University Plasmonic assisted systems and methods for interior energy-activation from an exterior source
AU2016210665B2 (en) * 2007-04-08 2017-12-07 Immunolight, Llc Methods and systems for treating cell proliferation disorders
WO2010009106A1 (en) 2008-07-14 2010-01-21 Bourke Frederic A Jr Advanced methods and systems for treating cell proliferation disorders
EP2351471A1 (de) * 2008-09-29 2011-08-03 Nederlandse Organisatie voor toegepast -natuurwetenschappelijk onderzoek TNO Kit zum erstellen einer leitfähigen struktur
GB2464958A (en) * 2008-10-31 2010-05-05 Univ Muenster Wilhelms A method for the manufacture of a photosensitising nano-material
US9216198B2 (en) * 2009-03-30 2015-12-22 The Board Of Regents, The University Of Texas System Compositions and medical devices for controlled release of nitric oxide and methods of production thereof
US20110206737A1 (en) * 2010-02-24 2011-08-25 Empire Technology Development Llc Photosensitizer-containing composition
US9368250B2 (en) * 2010-03-15 2016-06-14 Masayuki Kanehara Nanoink composition
WO2013192609A1 (en) 2012-06-22 2013-12-27 Cornell University Mesoporous oxide nanoparticles and methods of making and using same
JP2015128096A (ja) * 2013-12-27 2015-07-09 ソニー株式会社 分散体、光電変換素子および撮像装置
US10420346B2 (en) 2014-03-07 2019-09-24 University Of Cincinnati Silver nanoparticle-enhanced photosensitizers
WO2015134204A1 (en) * 2014-03-07 2015-09-11 University Of Cincinnati Silver nanoparticle-enhanced photosensitizers
ES2575127B2 (es) * 2014-12-23 2016-10-05 Universidad Miguel Hernández De Elche Mercaptoftalocianinas, procedimiento de preparación de las mismas y su anclaje a nanopartículas metálicas
WO2016203431A1 (en) 2015-06-18 2016-12-22 Universita' Ca' Foscari Luminescent bismuth silicates, use and method for producing thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5178986A (en) * 1988-10-17 1993-01-12 Shipley Company Inc. Positive photoresist composition with naphthoquinonediazidesulfonate of oligomeric phenol
WO1997010811A1 (en) 1995-09-21 1997-03-27 Novartis Ag Nanoparticles in photodynamic therapy
CA2329859A1 (en) 1998-04-20 1999-12-02 Allen C. Templeton Nanometer particles containing a reactive monolayer
EP1206288B1 (de) * 1999-08-02 2007-01-10 The Regents Of The University Of Michigan Zielgerichtete fiberlose radiative effektoren

Also Published As

Publication number Publication date
WO2003037297A2 (en) 2003-05-08
US20050058713A1 (en) 2005-03-17
EP1455828B1 (de) 2006-08-02
GB0126236D0 (en) 2002-01-02
AU2002341159A1 (en) 2003-05-12
WO2003037297A3 (en) 2003-08-28
ES2268100T3 (es) 2007-03-16
AU2002341159A8 (en) 2005-10-13
DE60213655T2 (de) 2007-10-04
US7563818B2 (en) 2009-07-21
EP1455828A2 (de) 2004-09-15
DE60213655D1 (de) 2006-09-14
CA2465401A1 (en) 2003-05-08

Similar Documents

Publication Publication Date Title
ATE334699T1 (de) Photosensitize funktionalisierte nanopartikel
Yuan et al. Luminescent noble metal nanoclusters as an emerging optical probe for sensor development
Yang et al. Efficient and Monochromatic Electrochemiluminescence of Aqueous‐Soluble Au Nanoclusters via Host–Guest Recognition
Dai et al. Nanozymes for regulation of reactive oxygen species and disease therapy
Cui et al. Synthesis, optical properties and applications of ultra-small luminescent gold nanoclusters
Si et al. A mechanistic and kinetic study of the formation of metal nanoparticles by using synthetic tyrosine‐based oligopeptides
Himmelwright et al. Chemical and spectroscopic comparison of the binuclear copper active site of mollusc and arthropod hemocyanins
Qi et al. Nanomaterials-modulated Fenton reactions: Strategies, chemodynamic therapy and future trends
Xiang et al. Transition‐metal nitrosyls for photocontrolled nitric oxide delivery
Himmelwright et al. Comparison of half-met and met apo hemocyanin. Ligand bridging at the binuclear copper active site
Habeeb Muhammed et al. Au25@ SiO2: quantum clusters of gold embedded in silica
CN102191034A (zh) 一种n-(4-氨基丁基)-n-乙基异鲁米诺发光功能化的纳米金及其制备方法和应用
AU2002367579A8 (en) Synthesis of stable colloidal nanocrystals using organic dendrons
BR0316886A (pt) Composição, processo para a preparação de uma composição, produto para contraste, usos de uma composição e uso de partìculas magnéticas
Dumur et al. Functionalization of gold nanoparticles by inorganic entities
Mooi et al. Amplified production of singlet oxygen in aqueous solution using metal enhancement effects
Shi et al. Strategies for the functionalisation of gold nanorods to reduce toxicity and aid clinical translation
Mapukata et al. The photodynamic antimicrobial chemotherapy of Stapphylococcus aureus using an asymmetrical zinc phthalocyanine conjugated to silver and iron oxide based nanoparticles
Kumar et al. A three-component supramolecular nanocomposite as a heavy-atom-free photosensitizer
Farkhani et al. Tailoring gold nanocluster properties for biomedical applications: from sensing to bioimaging and theranostics
Bhunia et al. Gold nanocluster-grafted cyclodextrin suprastructures: formation of nanospheres to nanocubes with intriguing photophysics
CN110975796A (zh) 一种纳米马达及其制备方法和应用
Hollingsworth et al. Preparation of metalloporphyrin-bound superparamagnetic silica particles via “Click” reaction
Do et al. Photodynamic and photothermal effects of carbon dot-coated magnetite-and porphyrin-conjugated confeito-like gold nanoparticles
CN109283168A (zh) 一种基于两性纳米颗粒的高灵敏度sers分子检测方法

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties