ATE329691T1 - Verfahren zur behandlung einer matrixnukleinsäure unter verwendung einer integrierten mikrofluidischen platte - Google Patents

Verfahren zur behandlung einer matrixnukleinsäure unter verwendung einer integrierten mikrofluidischen platte

Info

Publication number
ATE329691T1
ATE329691T1 AT00991793T AT00991793T ATE329691T1 AT E329691 T1 ATE329691 T1 AT E329691T1 AT 00991793 T AT00991793 T AT 00991793T AT 00991793 T AT00991793 T AT 00991793T AT E329691 T1 ATE329691 T1 AT E329691T1
Authority
AT
Austria
Prior art keywords
nucleic acid
treating
integrated microfluidic
thermocycling reaction
microfluidic plate
Prior art date
Application number
AT00991793T
Other languages
English (en)
Inventor
Nigel Eric Tooke
Per Andersson
Original Assignee
Gyros Patent Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/EP1999/010347 external-priority patent/WO2000040750A1/en
Priority claimed from GBGB0011425.6A external-priority patent/GB0011425D0/en
Application filed by Gyros Patent Ab filed Critical Gyros Patent Ab
Application granted granted Critical
Publication of ATE329691T1 publication Critical patent/ATE329691T1/de

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0631—Purification arrangements, e.g. solid phase extraction [SPE]
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0803—Disc shape
    • B01L2300/0806—Standardised forms, e.g. compact disc [CD] format
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/087—Multiple sequential chambers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0409—Moving fluids with specific forces or mechanical means specific forces centrifugal forces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0415—Moving fluids with specific forces or mechanical means specific forces electrical forces, e.g. electrokinetic
    • B01L2400/0421—Moving fluids with specific forces or mechanical means specific forces electrical forces, e.g. electrokinetic electrophoretic flow
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/08—Regulating or influencing the flow resistance
    • B01L2400/084—Passive control of flow resistance
    • B01L2400/088—Passive control of flow resistance by specific surface properties
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L7/00—Heating or cooling apparatus; Heat insulating devices
    • B01L7/52—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Clinical Laboratory Science (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Saccharide Compounds (AREA)
  • Purification Treatments By Anaerobic Or Anaerobic And Aerobic Bacteria Or Animals (AREA)
  • Cereal-Derived Products (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
AT00991793T 1999-12-23 2000-12-20 Verfahren zur behandlung einer matrixnukleinsäure unter verwendung einer integrierten mikrofluidischen platte ATE329691T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PCT/EP1999/010347 WO2000040750A1 (en) 1998-12-30 1999-12-23 Method for sequencing dna using a microfluidic device
GBGB0011425.6A GB0011425D0 (en) 1999-12-23 2000-05-12 Integrated microfluidic disc

Publications (1)

Publication Number Publication Date
ATE329691T1 true ATE329691T1 (de) 2006-07-15

Family

ID=26070393

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00991793T ATE329691T1 (de) 1999-12-23 2000-12-20 Verfahren zur behandlung einer matrixnukleinsäure unter verwendung einer integrierten mikrofluidischen platte

Country Status (5)

Country Link
JP (1) JP4791670B2 (de)
AT (1) ATE329691T1 (de)
AU (1) AU3537001A (de)
DE (1) DE60028819T2 (de)
WO (1) WO2001047638A2 (de)

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US7014815B1 (en) 1998-10-30 2006-03-21 Burstein Technologies, Inc. Trackable optical discs with concurrently readable nonoperational features
WO2001087487A2 (en) * 2000-05-15 2001-11-22 Tecan Trading Ag Bidirectional flow centrifugal microfluidic devices
US7087203B2 (en) 2000-11-17 2006-08-08 Nagaoka & Co., Ltd. Methods and apparatus for blood typing with optical bio-disc
US7026131B2 (en) 2000-11-17 2006-04-11 Nagaoka & Co., Ltd. Methods and apparatus for blood typing with optical bio-discs
WO2002046721A2 (en) 2000-12-08 2002-06-13 Burstein Technologies, Inc. Optical discs for measuring analytes
US7054258B2 (en) 2000-12-08 2006-05-30 Nagaoka & Co., Ltd. Optical disc assemblies for performing assays
US7091034B2 (en) 2000-12-15 2006-08-15 Burstein Technologies, Inc. Detection system for disk-based laboratory and improved optical bio-disc including same
US7429354B2 (en) 2001-03-19 2008-09-30 Gyros Patent Ab Structural units that define fluidic functions
JP4323806B2 (ja) 2001-03-19 2009-09-02 ユィロス・パテント・アクチボラグ 反応可変要素の特徴付け
US6726820B1 (en) 2001-09-19 2004-04-27 Applera Corporation Method of separating biomolecule-containing samples with a microdevice with integrated memory
US20080288178A1 (en) 2001-08-24 2008-11-20 Applera Corporation Sequencing system with memory
EP2281633A1 (de) 2001-08-28 2011-02-09 Gyros Patent Ab Mikrokammern und mikrofluidische Strukturen zur Handhabung kleiner Flüssigkeitsmengen
US6919058B2 (en) 2001-08-28 2005-07-19 Gyros Ab Retaining microfluidic microcavity and other microfluidic structures
DE60237289D1 (de) 2001-09-17 2010-09-23 Gyros Patent Ab Einen kontrollierten strom in einer mikrofluidvorrichtung ermöglichende funktionseinheit
US7662340B2 (en) * 2001-12-28 2010-02-16 Hitachi High-Technologies Corporation Extractor chemical analyzer and chemical analyzing method
US6532997B1 (en) 2001-12-28 2003-03-18 3M Innovative Properties Company Sample processing device with integral electrophoresis channels
AU2003224586A1 (en) * 2002-04-30 2003-11-17 Gyros Ab Integrated microfluidic device (ea)
US7005265B1 (en) 2002-06-20 2006-02-28 Wenhong Fan Nonenzymatic catalytic signal amplification for nucleic acid hybridization assays
JP2004354364A (ja) 2002-12-02 2004-12-16 Nec Corp 微粒子操作ユニット、それを搭載したチップと検出装置、ならびにタンパク質の分離、捕獲、および検出方法
US7390464B2 (en) 2003-06-19 2008-06-24 Burstein Technologies, Inc. Fluidic circuits for sample preparation including bio-discs and methods relating thereto
US7238269B2 (en) 2003-07-01 2007-07-03 3M Innovative Properties Company Sample processing device with unvented channel
US7776272B2 (en) 2003-10-03 2010-08-17 Gyros Patent Ab Liquid router
US7837947B2 (en) * 2003-12-12 2010-11-23 3M Innovative Properties Company Sample mixing on a microfluidic device
SE0400181D0 (sv) * 2004-01-29 2004-01-29 Gyros Ab Segmented porous and preloaded microscale devices
US7187286B2 (en) 2004-03-19 2007-03-06 Applera Corporation Methods and systems for using RFID in biological field
TWI295730B (en) * 2004-11-25 2008-04-11 Ind Tech Res Inst Microfluidic chip for sample assay and method thereof
EP1874469A4 (de) 2005-04-14 2014-02-26 Gyros Patent Ab Mikrofluidvorrichtung mit fingerventilen
DK1883474T3 (da) 2005-05-25 2021-06-21 Boehringer Ingelheim Vetmedica Gmbh System til integreret og automatiseret dna- eller proteinanalyse og fremgangsmåde til at drive et sådan system
US10816563B2 (en) 2005-05-25 2020-10-27 Boehringer Ingelheim Vetmedica Gmbh System for operating a system for the integrated and automated analysis of DNA or protein
US20090075801A1 (en) * 2007-09-19 2009-03-19 Dalibor Hodko Counter-centrifugal force device
WO2012033765A1 (en) 2010-09-07 2012-03-15 The Arizona Board Of Regents On Behalf Of The University Of Arizona Microdroplet-manipulation systems and methods for automated execution of molecular biological protocols
US9993819B2 (en) 2014-12-30 2018-06-12 Stmicroelectronics S.R.L. Apparatus for actuating and reading a centrifugal microfluidic disk for biological and biochemical analyses, and use of the apparatus
TW201818076A (zh) 2016-10-07 2018-05-16 德商百靈佳殷格翰維美迪加股份有限公司 用於檢測樣本之分析裝置及方法
WO2018065102A1 (en) 2016-10-07 2018-04-12 Boehringer Ingelheim Vetmedica Gmbh Method and analysis system for testing a sample
US11112416B2 (en) 2018-01-30 2021-09-07 Life Technologies Corporation Instruments, devices and consumables for use in a workflow of a smart molecular analysis system

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US5585069A (en) * 1994-11-10 1996-12-17 David Sarnoff Research Center, Inc. Partitioned microelectronic and fluidic device array for clinical diagnostics and chemical synthesis
EP0862647A1 (de) * 1995-11-03 1998-09-09 Sarnoff Corporation Testsystem und verfahren zur ausführung von testverfahren
CA2239613A1 (en) * 1995-12-05 1997-06-12 Alec Mian Devices and methods for using centripetal acceleration to drive fluid movement in a microfluidics system with on-board informatics
TR199902440T2 (xx) * 1997-02-28 2000-02-21 Burstein Laboratories, Inc. Disk �zerinde laboratuar.
US6013513A (en) * 1997-10-30 2000-01-11 Motorola, Inc. Molecular detection apparatus
GB9828785D0 (en) * 1998-12-30 1999-02-17 Amersham Pharm Biotech Ab Sequencing systems
EP1192006B1 (de) * 1999-06-22 2008-05-14 Tecan Trading AG Vorrichtungen zur durchfuehrung von miniaturisierten in vitro amplifizierungsassays

Also Published As

Publication number Publication date
WO2001047638A3 (en) 2002-05-30
DE60028819T2 (de) 2007-01-11
WO2001047638A2 (en) 2001-07-05
AU3537001A (en) 2001-07-09
JP2003520582A (ja) 2003-07-08
JP4791670B2 (ja) 2011-10-12
DE60028819D1 (de) 2006-07-27

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