ATE328280T1 - Verfahren und zusammensetzungen zur karzinomdiagnose - Google Patents
Verfahren und zusammensetzungen zur karzinomdiagnoseInfo
- Publication number
- ATE328280T1 ATE328280T1 AT00908795T AT00908795T ATE328280T1 AT E328280 T1 ATE328280 T1 AT E328280T1 AT 00908795 T AT00908795 T AT 00908795T AT 00908795 T AT00908795 T AT 00908795T AT E328280 T1 ATE328280 T1 AT E328280T1
- Authority
- AT
- Austria
- Prior art keywords
- mra
- compositions
- methods
- mesothelin
- subject
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- 239000000203 mixture Substances 0.000 title abstract 2
- 201000009030 Carcinoma Diseases 0.000 title 1
- 238000003745 diagnosis Methods 0.000 title 1
- 102000003735 Mesothelin Human genes 0.000 abstract 3
- 108090000015 Mesothelin Proteins 0.000 abstract 3
- 230000003211 malignant effect Effects 0.000 abstract 2
- 238000012216 screening Methods 0.000 abstract 2
- 108091028043 Nucleic acid sequence Proteins 0.000 abstract 1
- 239000000427 antigen Substances 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 238000001514 detection method Methods 0.000 abstract 1
- 238000009396 hybridization Methods 0.000 abstract 1
- 150000007523 nucleic acids Chemical group 0.000 abstract 1
- 239000002773 nucleotide Substances 0.000 abstract 1
- 125000003729 nucleotide group Chemical group 0.000 abstract 1
- 230000009257 reactivity Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
- C07K16/3069—Reproductive system, e.g. ovaria, uterus, testes, prostate
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/57449—Specifically defined cancers of ovaries
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
- G01N33/57488—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving compounds identifable in body fluids
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Cell Biology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Hospice & Palliative Care (AREA)
- Food Science & Technology (AREA)
- Organic Chemistry (AREA)
- Pathology (AREA)
- Oncology (AREA)
- General Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Reproductive Health (AREA)
- Gynecology & Obstetrics (AREA)
- Pregnancy & Childbirth (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US12176799P | 1999-02-26 | 1999-02-26 | |
| US14740499P | 1999-08-05 | 1999-08-05 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE328280T1 true ATE328280T1 (de) | 2006-06-15 |
Family
ID=26819780
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT00908795T ATE328280T1 (de) | 1999-02-26 | 2000-02-25 | Verfahren und zusammensetzungen zur karzinomdiagnose |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP1169645B1 (de) |
| JP (3) | JP4813661B2 (de) |
| AT (1) | ATE328280T1 (de) |
| AU (1) | AU3007200A (de) |
| CA (1) | CA2369433A1 (de) |
| DE (1) | DE60028361T2 (de) |
| ES (1) | ES2269105T3 (de) |
| WO (1) | WO2000050900A2 (de) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7030219B2 (en) | 2000-04-28 | 2006-04-18 | Johns Hopkins University | B7-DC, Dendritic cell co-stimulatory molecules |
| US7270960B2 (en) | 2001-08-29 | 2007-09-18 | Pacific Northwest Research Institute | Diagnosis of ovarian carcinomas |
| US20090110702A1 (en) | 2002-07-12 | 2009-04-30 | The Johns Hopkins University | Mesothelin Vaccines and Model Systems and Control of Tumors |
| US9200036B2 (en) | 2002-07-12 | 2015-12-01 | The Johns Hopkins University | Mesothelin vaccines and model systems |
| JP2006521090A (ja) | 2002-07-12 | 2006-09-21 | ザ ジョンズ ホプキンス ユニバーシティー | メゾテリンワクチンおよびモデルシステム |
| US20040180387A1 (en) * | 2003-03-13 | 2004-09-16 | Fujirebio Diagnostics, Inc. | Detection of urinary mesothelin-/megakaryocyte potentiating factor-related peptides for assessment of ovarian cancer |
| WO2005014652A1 (en) * | 2003-08-05 | 2005-02-17 | Morphotek, Inc. | A variant cell surface molecule associated with cancer |
| EP1716168A4 (de) * | 2004-01-21 | 2009-06-24 | Fujirebio America Inc | Nachweis von mit dem urinary mesothelin-/ megakaryocyte potentiating factor verwandten peptiden zur untersuchung von mesotheliomen |
| EP2444805A3 (de) | 2004-01-21 | 2012-06-20 | Fujirebio America, Inc. | Erkennung von Mesothelin-/Megakaryozyten zur Potenzierung von faktorbezogenen Peptiden in peritonealer Flüssigkeit zur Bewertung des Peritoneum und Peritonealhöhle |
| CN101473041B (zh) | 2006-01-04 | 2017-11-14 | 富士瑞必欧美国公司 | He4与其它生化标记物在评估子宫内膜癌和子宫癌中的应用 |
| JP5207437B2 (ja) * | 2006-06-27 | 2013-06-12 | 独立行政法人理化学研究所 | 中皮由来組織特異的マーカーの同定及び検出方法 |
| US8268970B2 (en) | 2007-10-01 | 2012-09-18 | Bristol-Myers Squibb Company | Human antibodies that bind mesothelin, and uses thereof |
| PL2215121T3 (pl) * | 2007-11-26 | 2016-07-29 | Bayer Ip Gmbh | Przeciwciała przeciwko mezotelinie i ich zastosowania |
| WO2010080909A1 (en) | 2009-01-08 | 2010-07-15 | Yale University | Compositions and methods of use of an oncolytic vesicular stomatitis virus |
| AR076284A1 (es) | 2009-04-29 | 2011-06-01 | Bayer Schering Pharma Ag | Inmunoconjugados de antimesotelina y usos de los mismos |
| WO2011032003A1 (en) | 2009-09-10 | 2011-03-17 | Yale University | Immunization to reduce neurotoxicity during treatment with cytolytic viruses |
| WO2011056993A1 (en) | 2009-11-04 | 2011-05-12 | Yale University | Compositions and methods for treating cancer with attenuated oncolytic viruses |
| US10874621B2 (en) | 2013-10-17 | 2020-12-29 | The Brigham And Women's Hospital, Inc. | Cationic nanoparticles for co-delivery of nucleic acids and therapeutic agents |
| ES3007997T3 (en) | 2014-05-09 | 2025-03-21 | Univ Yale | Hyperbranched polyglycerol-coated particles |
| US11918695B2 (en) | 2014-05-09 | 2024-03-05 | Yale University | Topical formulation of hyperbranched polymer-coated particles |
| WO2016168197A1 (en) | 2015-04-15 | 2016-10-20 | Yale University | Compositions for enhancing delivery of agents across the blood brain barrier and methods of use thereof |
| WO2017095751A1 (en) | 2015-12-02 | 2017-06-08 | Partikula Llc | Compositions and methods for modulating cancer cell metabolism |
| WO2017173453A1 (en) | 2016-04-01 | 2017-10-05 | The Brigham And Women's Hospital, Inc. | Stimuli-responsive nanoparticles for biomedical applications |
| CN106248767B (zh) * | 2016-07-15 | 2018-12-07 | 济南大学 | 一种用于检测癌细胞中h2s的三维纸分析器件的制备方法 |
| JP2019533645A (ja) | 2016-09-16 | 2019-11-21 | ザ・ジョンズ・ホプキンス・ユニバーシティー | 標的組織および細胞内送達のための増大した粘膜浸透のタンパク質ナノケージ |
| US20200085758A1 (en) | 2016-12-16 | 2020-03-19 | The Brigham And Women's Hospital, Inc. | Co-delivery of nucleic acids for simultaneous suppression and expression of target genes |
| WO2018196782A1 (en) | 2017-04-27 | 2018-11-01 | The University Of Hong Kong | Use of hcn inhibitors for treatment of cancer |
| US11478433B2 (en) | 2017-06-23 | 2022-10-25 | Yale University | Nanomaterials with enhanced drug delivery efficiency |
| JP2024527977A (ja) | 2021-07-27 | 2024-07-26 | ノヴァブ， インコーポレイテッド | 免疫エフェクター機能を有する操作されたｖｌｒｂ抗体 |
| US20250114455A1 (en) | 2022-01-28 | 2025-04-10 | University Of Georgia Research Foundation, Inc. | Radiosensitizing compositions and methods of use thereof |
| EP4622631A1 (de) | 2022-11-23 | 2025-10-01 | University of Georgia Research Foundation, Inc. | Zusammensetzungen und verfahren zur verwendung davon zur erhöhung der immunreaktionen |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1992007081A2 (en) * | 1990-10-12 | 1992-04-30 | THE UNITED STATES OF AMERICA as represented by TH E SECRETARY, U.S. DEPARTMENT OF COMMERCE | A monoclonal antibody |
| IL107366A (en) * | 1992-10-23 | 2003-03-12 | Chugai Pharmaceutical Co Ltd | Genes coding for megakaryocyte potentiator |
| CA2241604C (en) * | 1996-01-05 | 2010-03-30 | Ira Pastan | Mesothelium antigen and methods and kits for targeting it |
-
2000
- 2000-02-25 AT AT00908795T patent/ATE328280T1/de not_active IP Right Cessation
- 2000-02-25 JP JP2000601444A patent/JP4813661B2/ja not_active Expired - Lifetime
- 2000-02-25 CA CA002369433A patent/CA2369433A1/en not_active Abandoned
- 2000-02-25 DE DE60028361T patent/DE60028361T2/de not_active Expired - Lifetime
- 2000-02-25 EP EP00908795A patent/EP1169645B1/de not_active Expired - Lifetime
- 2000-02-25 AU AU30072/00A patent/AU3007200A/en not_active Abandoned
- 2000-02-25 ES ES00908795T patent/ES2269105T3/es not_active Expired - Lifetime
- 2000-02-25 WO PCT/US2000/004834 patent/WO2000050900A2/en not_active Ceased
-
2010
- 2010-01-25 JP JP2010013579A patent/JP2010096774A/ja not_active Withdrawn
-
2011
- 2011-07-25 JP JP2011162531A patent/JP2011206062A/ja not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| WO2000050900A2 (en) | 2000-08-31 |
| DE60028361D1 (de) | 2006-07-06 |
| EP1169645B1 (de) | 2006-05-31 |
| EP1169645A2 (de) | 2002-01-09 |
| ES2269105T3 (es) | 2007-04-01 |
| WO2000050900A3 (en) | 2001-08-23 |
| JP4813661B2 (ja) | 2011-11-09 |
| CA2369433A1 (en) | 2000-08-31 |
| DE60028361T2 (de) | 2007-05-10 |
| JP2002538434A (ja) | 2002-11-12 |
| AU3007200A (en) | 2000-09-14 |
| JP2011206062A (ja) | 2011-10-20 |
| JP2010096774A (ja) | 2010-04-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |