ATE324365T1 - Phenoxyphenylheterozyklen als serotonin- wiederaufnahmehemmer - Google Patents

Phenoxyphenylheterozyklen als serotonin- wiederaufnahmehemmer

Info

Publication number
ATE324365T1
ATE324365T1 AT01307032T AT01307032T ATE324365T1 AT E324365 T1 ATE324365 T1 AT E324365T1 AT 01307032 T AT01307032 T AT 01307032T AT 01307032 T AT01307032 T AT 01307032T AT E324365 T1 ATE324365 T1 AT E324365T1
Authority
AT
Austria
Prior art keywords
heteroatoms
c6alkyl
nitrogen
heterocyclic ring
atoms
Prior art date
Application number
AT01307032T
Other languages
English (en)
Inventor
Mark David Andrews
David Hepworth
Donald Stuart Middleton
Alan Stobie
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0021594A external-priority patent/GB0021594D0/en
Priority claimed from GB0105634A external-priority patent/GB0105634D0/en
Application filed by Pfizer filed Critical Pfizer
Application granted granted Critical
Publication of ATE324365T1 publication Critical patent/ATE324365T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
    • C07D207/09—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
AT01307032T 2000-08-31 2001-08-17 Phenoxyphenylheterozyklen als serotonin- wiederaufnahmehemmer ATE324365T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0021594A GB0021594D0 (en) 2000-08-31 2000-08-31 Diphenyl ether compounds useful in therapy
GB0105634A GB0105634D0 (en) 2001-03-07 2001-03-07 Novel compounds

Publications (1)

Publication Number Publication Date
ATE324365T1 true ATE324365T1 (de) 2006-05-15

Family

ID=26244954

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01307032T ATE324365T1 (de) 2000-08-31 2001-08-17 Phenoxyphenylheterozyklen als serotonin- wiederaufnahmehemmer

Country Status (7)

Country Link
EP (1) EP1184372B1 (de)
JP (1) JP3802782B2 (de)
AT (1) ATE324365T1 (de)
BR (1) BR0103797A (de)
CA (1) CA2356065C (de)
DE (1) DE60119047D1 (de)
MX (1) MXPA01008860A (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6436938B1 (en) * 2001-01-22 2002-08-20 Pfizer Inc. Combination treatment for depression
US7550485B2 (en) * 2003-10-14 2009-06-23 Wyeth Substituted N-heterocycle derivatives and methods of their use
ES2340130B1 (es) * 2008-11-27 2011-03-22 Consejo Superior De Investigaciones Cientificas (Csic) Funcionalizacion de 1-vinil-2 pirrolidona en posicion 3 mediante apertura de precursores ciclicos.
CA2803090A1 (en) * 2010-07-09 2012-01-12 Theravance, Inc. Crystalline form of a 3-phenoxymethylpyrrolidine compound
AU2020282757A1 (en) * 2019-05-31 2021-12-23 Ikena Oncology, Inc. TEAD inhibitors and uses thereof
MX2021014441A (es) 2019-05-31 2022-01-06 Ikena Oncology Inc Inhibidores del dominio asociado mejorador de la transcripcion (tead) y usos de los mismos.
US20240083903A1 (en) * 2021-02-18 2024-03-14 Merck Sharp & Dohme Llc Aryl ether compounds as tead modulators

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4536518A (en) * 1979-11-01 1985-08-20 Pfizer Inc. Antidepressant derivatives of cis-4-phenyl-1,2,3,4-tetrahydro-1-naphthalenamine
ZA923283B (en) * 1991-05-29 1993-01-27 Akzo Nv Phenoxyphenyl derivatives
GB2276162A (en) * 1993-03-17 1994-09-21 Glaxo Group Ltd Aniline and benazilide derivatives
JP3916871B2 (ja) * 1999-02-23 2007-05-23 ファイザー・プロダクツ・インク Ｃｎｓ障害の治療のためのモノアミン再吸収阻害剤

Also Published As

Publication number Publication date
EP1184372B1 (de) 2006-04-26
DE60119047D1 (de) 2006-06-01
JP3802782B2 (ja) 2006-07-26
CA2356065C (en) 2005-04-12
EP1184372A1 (de) 2002-03-06
JP2002114762A (ja) 2002-04-16
MXPA01008860A (es) 2002-08-20
CA2356065A1 (en) 2002-02-28
BR0103797A (pt) 2002-06-04

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Legal Events

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