ATE322896T1 - Verbesserte pharmazeutische zusammensetzung mit einem ppar-alpha-mittel und verfahren zu ihrer herstellung - Google Patents

Verbesserte pharmazeutische zusammensetzung mit einem ppar-alpha-mittel und verfahren zu ihrer herstellung

Info

Publication number
ATE322896T1
ATE322896T1 AT02748487T AT02748487T ATE322896T1 AT E322896 T1 ATE322896 T1 AT E322896T1 AT 02748487 T AT02748487 T AT 02748487T AT 02748487 T AT02748487 T AT 02748487T AT E322896 T1 ATE322896 T1 AT E322896T1
Authority
AT
Austria
Prior art keywords
pharmaceutical composition
ppar
production
composition containing
improved pharmaceutical
Prior art date
Application number
AT02748487T
Other languages
English (en)
Inventor
Francis Vanderbist
Philippe Baudier
Antonio Sereno
Original Assignee
Smb Sa Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smb Sa Lab filed Critical Smb Sa Lab
Application granted granted Critical
Publication of ATE322896T1 publication Critical patent/ATE322896T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/225—Polycarboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/216—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT02748487T 2001-08-07 2002-07-17 Verbesserte pharmazeutische zusammensetzung mit einem ppar-alpha-mittel und verfahren zu ihrer herstellung ATE322896T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
BE0100133 2001-08-07
PCT/BE2002/000051 WO2003013501A1 (en) 2001-08-07 2002-04-05 Improved pharmaceutical composition containing a ppar alpha agent and a process for preparing it

Publications (1)

Publication Number Publication Date
ATE322896T1 true ATE322896T1 (de) 2006-04-15

Family

ID=3862570

Family Applications (2)

Application Number Title Priority Date Filing Date
AT02748487T ATE322896T1 (de) 2001-08-07 2002-07-17 Verbesserte pharmazeutische zusammensetzung mit einem ppar-alpha-mittel und verfahren zu ihrer herstellung
AT02766983T ATE485058T1 (de) 2001-08-07 2002-08-07 Zusammensetzung enthaltend eine kombination aus einem ppar-alpha, pravastatin und polyglykolisiertem glyzerid

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT02766983T ATE485058T1 (de) 2001-08-07 2002-08-07 Zusammensetzung enthaltend eine kombination aus einem ppar-alpha, pravastatin und polyglykolisiertem glyzerid

Country Status (7)

Country Link
US (2) US20070092567A1 (de)
AT (2) ATE322896T1 (de)
DE (1) DE60238059D1 (de)
DK (1) DK1414496T3 (de)
ES (1) ES2352189T3 (de)
PT (1) PT1414496E (de)
WO (2) WO2003013607A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2534660A1 (en) * 2003-08-05 2005-02-10 Galephar M/F Single unit pharmaceutical composition comprising a mixture of a fibrate and an homocysteine reducing agent
WO2005013940A1 (en) * 2003-08-06 2005-02-17 Galephar M/F Stable controlled release pharmaceutical compositions containing fenofibrate and pravastatin
CN103040798A (zh) * 2011-11-08 2013-04-17 深圳信立泰药业股份有限公司 一种苯扎贝特缓释药物组合物
CN110496108A (zh) * 2011-12-14 2019-11-26 Lts勒曼治疗系统股份公司 用于非诺贝特的具有提高的溶出度的糯米纸囊制剂和胶囊制剂
KR102501636B1 (ko) * 2021-12-07 2023-02-21 에이스바이오팜 주식회사 페노피브린산을 포함하는 경구용 정제 및 이의 제조방법

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2039763A1 (en) * 1990-04-30 1991-10-31 Henry Y. Pan Combination of pravastatin and a fibric acid derivative, and method for treating dyslipidemia using such combination
CA2048395A1 (en) * 1990-08-23 1992-02-24 Henry Y. Pan Method for preventing onset of or treating type iii hyperlipoproteinemia employing pravastatin
BE1011363A3 (fr) * 1997-09-11 1999-08-03 Smb Technology Capsules semi-solides autoemulsionnables matricielles a action prolongee.
DE19858789A1 (de) * 1998-12-18 2000-06-21 Bayer Ag Kombination von Cerivastatin und Fibraten
US6383471B1 (en) * 1999-04-06 2002-05-07 Lipocine, Inc. Compositions and methods for improved delivery of ionizable hydrophobic therapeutic agents
US6368620B2 (en) * 1999-06-11 2002-04-09 Abbott Laboratories Formulations comprising lipid-regulating agents
US6372251B2 (en) * 1999-06-11 2002-04-16 Abbott Laboratories Formulations comprising lipid-regulating agents
JP2003509453A (ja) * 1999-09-21 2003-03-11 アールティーピー・ファーマ・インコーポレーテッド 生物学的に活性な物質の、表面改質された粒状組成物
HRP20020950A2 (en) * 2000-06-09 2004-12-31 Lek Tovarna Farmacevtskih Stabilized pharmaceutically effective composition and pharmaceutical formulation comprising the same
US6534088B2 (en) * 2001-02-22 2003-03-18 Skyepharma Canada Inc. Fibrate-statin combinations with reduced fed-fasted effects
US6576256B2 (en) * 2001-08-28 2003-06-10 The Brigham And Women's Hospital, Inc. Treatment of patients at elevated cardiovascular risk with a combination of a cholesterol-lowering agent, an inhibitor of the renin-angiotensin system, and aspirin

Also Published As

Publication number Publication date
WO2003013501A1 (en) 2003-02-20
US20150037414A1 (en) 2015-02-05
PT1414496E (pt) 2012-04-20
WO2003013607A1 (en) 2003-02-20
DE60238059D1 (de) 2010-12-02
DK1414496T3 (da) 2011-01-24
US20070092567A1 (en) 2007-04-26
ES2352189T3 (es) 2011-02-16
ATE485058T1 (de) 2010-11-15

Similar Documents

Publication Publication Date Title
DE3381680D1 (de) 1,4-dihydropyridincarbonsaeure-ester, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zusammensetzungen.
DE59906017D1 (de) Benzocycloheptene, verfahren zu ihrer herstellung, pharmazeutische präparate die diese enthalten sowie deren verwendung zur herstellung von arzneimitteln
EP1452172A3 (de) Aus mehreren Einzeleinheiten zusammengesetztes pharmazeutisches Präparat.
EA199600028A2 (ru) Оральная композиция, содержащая s(+)-ибупрофен, и способ ее получения
LV12399A (lv) Uzlabotas vienreiz diena lietojamas pulsejosas miniciklina mogades sistemas
BRPI9509286B8 (pt) microcápsulas medicamentosas e/ou nutricionais para administração per si.
HUT57541A (en) Fungicidal compositions comprising substituted acrylic acid esters as active ingredient and process for producing the active ingredients
ATE128028T1 (de) Pharmazeutische zubereitung in form einer brause- und/oder zerfallstablette oder eines instantgranulats, sowie verfahren zu ihrer herstellung.
GB8819110D0 (en) Antihypertensive drug & method for production
EP0656776A1 (de) Mehrschichttabletten mit gesteuerter wirkstoffabgabe enthaltend sowohl naproxen als auch naproxen natriumsalz.
AU4846690A (en) Polyunsaturated fatty acid derivatives, pharmaceutical compositions containing the same, method for the preparation thereof, and their use as medicament
NZ217703A (en) 2-(2-fluoro-4-biphenylyl) propionic acid compositions
ATE258792T1 (de) Diät mit hohem lipidgehalt
DE59400446D1 (de) Brausesystem mit einem alkali- und/oder metallempfindlichen, pharmazeutischen Wirkstoff, und Verfahren zur Herstellung
BRPI0412697A (pt) composições farmacêuticas que apresentam um revestimento expansìvel
EP0341707A3 (en) Phenylethanol ester of ortho-cinnamic acid, its preparation and use as fragrance compound
BR0107899A (pt) Processo para produzir uma preparação de ingrediente ativo compreendendo ibuprofeno, preparação de ingrediente ativo, uso da mesma, preparação farmacêutica, uso da mesma, processo para produzir formas de dosagem sólidas, e, forma de dosagem sólida
EP1637137A3 (de) Verfahren und Zusammensetzung zur Verabreichung eines Cyclooxygenase-2-Inhibitors an Tiere
GB8812653D0 (en) Pharmaceutical composition based on high concentration esters of docosahexaenoic acid
ES2125215T3 (es) Procedimiento para la preparacion de un producto de retardo que contiene diltiazem para una administracion diaria unica.
SI1651194T1 (sl) Stabilni farmacevtski sestavki za nadzorovano sproščanje, ki vsebujejo fenofibrat in pravastatin
JPS6468316A (en) External plaster containing salbutamol
ATE485058T1 (de) Zusammensetzung enthaltend eine kombination aus einem ppar-alpha, pravastatin und polyglykolisiertem glyzerid
HUT51105A (en) Pesticide comprising substituted acrylic acid ester derivatives as active ingredient and process for producing the active ingredients
DE59404739D1 (de) Dextranester, verfahren zu ihrer herstellung und ihre verwendung zur umhüllung oder einbettung von arzneimitteln

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties