ATE321565T1 - Behandlung von osteoporose - Google Patents

Behandlung von osteoporose

Info

Publication number
ATE321565T1
ATE321565T1 AT99923352T AT99923352T ATE321565T1 AT E321565 T1 ATE321565 T1 AT E321565T1 AT 99923352 T AT99923352 T AT 99923352T AT 99923352 T AT99923352 T AT 99923352T AT E321565 T1 ATE321565 T1 AT E321565T1
Authority
AT
Austria
Prior art keywords
bone
receptor
cell surface
formation
condition
Prior art date
Application number
AT99923352T
Other languages
English (en)
Inventor
Stephen Shaughnessy
Richard Carl Austin
Original Assignee
Hamilton Civic Hospitals Res
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hamilton Civic Hospitals Res filed Critical Hamilton Civic Hospitals Res
Application granted granted Critical
Publication of ATE321565T1 publication Critical patent/ATE321565T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C07K14/5431—IL-11
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7155—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for interleukins [IL]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Cell Biology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Display Devices Of Pinball Game Machines (AREA)
  • Superconductors And Manufacturing Methods Therefor (AREA)
AT99923352T 1998-05-19 1999-05-19 Behandlung von osteoporose ATE321565T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CA002237915A CA2237915A1 (en) 1998-05-19 1998-05-19 Osteoporosis treatment

Publications (1)

Publication Number Publication Date
ATE321565T1 true ATE321565T1 (de) 2006-04-15

Family

ID=4162449

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99923352T ATE321565T1 (de) 1998-05-19 1999-05-19 Behandlung von osteoporose

Country Status (8)

Country Link
US (3) US6998123B1 (de)
EP (2) EP1674108A3 (de)
JP (1) JP2002515444A (de)
AT (1) ATE321565T1 (de)
AU (1) AU767749B2 (de)
CA (1) CA2237915A1 (de)
DE (1) DE69930622D1 (de)
WO (1) WO1999059608A2 (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2237915A1 (en) 1998-05-19 1999-11-19 Stephen Shaughnessy Osteoporosis treatment
WO2003099322A2 (en) * 2002-05-24 2003-12-04 Isis Innovation Limited Il-11 derivatives and therapeutic uses thereof
WO2005065418A2 (en) * 2003-12-31 2005-07-21 Board Of Regents, The University Of Texas System Compositions and methods of use of targeting peptides for diagnosis and therapy
US8518888B2 (en) * 2008-10-14 2013-08-27 Csl Limited Method of treatment of gastrointestinal-type cancer with antagonistic antibodies to IL-11R
WO2011154413A1 (en) 2010-06-07 2011-12-15 Fritz-Lipmann-Insitut E. V. Leibniz-Institut Für Altersforschung Agent against glucocorticoid-induced osteoporosis
JP6959274B2 (ja) * 2013-02-07 2021-11-02 シーエスエル、リミテッド Ｉｌ−１１ｒ結合タンパク質及びその使用
EP4219552A3 (de) * 2013-02-07 2023-09-13 CSL Ltd. Il-11r-bindende proteine und verwendungen davon
GB201522186D0 (en) 2015-12-16 2016-01-27 Singapore Health Services Pte Ltd And Nat University Of Singapore The Treatment of fibrosis
GB201621439D0 (en) 2016-12-16 2017-02-01 Singapore Health Services Pte Ltd And Nat Univ Of Singapore IL-11Ra Antibodies
JP7181870B2 (ja) * 2016-12-16 2022-12-01 シンガポール・ヘルス・サービシーズ・ピーティーイー・リミテッド Ｉｌ－１１抗体
EP3914621A1 (de) 2019-01-21 2021-12-01 Singapore Health Services Pte. Ltd. Behandlung von hepatotoxizität
GB201902419D0 (en) 2019-02-22 2019-04-10 Singapore Health Serv Pte Ltd Treatment of kidney injury
CN114364693A (zh) 2019-05-03 2022-04-15 新加坡保健服务私人有限公司 代谢性疾病的治疗和预防
GB201906291D0 (en) 2019-05-03 2019-06-19 Singapore Health Serv Pte Ltd Treatment and prevention of metabolic diseases
GB202009292D0 (en) 2020-06-18 2020-08-05 Singapore Health Serv Pte Ltd Treatment and prevention of disease caused by type IV collagen dysfunction
GB202017244D0 (en) 2020-10-30 2020-12-16 Nat Univ Singapore Methods to extend health-span and treat age-related diseases
KR20230150287A (ko) 2021-02-26 2023-10-30 바이엘 악티엔게젤샤프트 비정상적 자궁 출혈의 치료에 사용하기 위한 il-11 또는 il-11ra의 억제제
EP4376948A1 (de) 2021-07-26 2024-06-05 Boehringer Ingelheim International GmbH Behandlung und prävention von alkoholischer lebererkrankung
EP4448096A1 (de) 2021-12-16 2024-10-23 Singapore Health Services Pte. Ltd. Behandlung und prävention von glomerulärer erkrankung

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4683195A (en) 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US5530101A (en) * 1988-12-28 1996-06-25 Protein Design Labs, Inc. Humanized immunoglobulins
US5215895A (en) 1989-11-22 1993-06-01 Genetics Institute, Inc. Dna encoding a mammalian cytokine, interleukin-11
US5292646A (en) 1991-02-06 1994-03-08 Genetics Institute, Inc. Peptide and protein fusions to thioredoxin and thioredoxin-like molecules
US5270181A (en) 1991-02-06 1993-12-14 Genetics Institute, Inc. Peptide and protein fusions to thioredoxin and thioredoxin-like molecules
US5888510A (en) * 1993-07-21 1999-03-30 Chugai Seiyaku Kabushiki Kaisha Chronic rheumatoid arthritis therapy containing IL-6 antagonist as effective component
IT1274350B (it) 1994-12-06 1997-07-17 Angeletti P Ist Richerche Bio Antagonisti di interleuchina-6(il-6) che consistono di forme solubili del ricettore alfa di il-6, mutate nell'interfaccia che si lega a gp 130
IT1274782B (it) * 1994-12-14 1997-07-24 Angeletti P Ist Richerche Bio Metodo per selezionare superagonisti, antagonisti e superantagonisti di ormoni del cui complesso recettoriale fa parte gp 130
JPH10511266A (ja) * 1994-12-22 1998-11-04 ジェネティックス・インスティテュート・インコーポレイテッド ヒト・インターロイキン−１１受容体
GB9621095D0 (en) * 1996-10-09 1996-11-27 Imperial College Novel system
CA2237915A1 (en) 1998-05-19 1999-11-19 Stephen Shaughnessy Osteoporosis treatment
US6777539B2 (en) * 2000-04-05 2004-08-17 Zymogenetics, Inc. Soluble zalpha11 cytokine receptors

Also Published As

Publication number Publication date
EP1079847A2 (de) 2001-03-07
CA2237915A1 (en) 1999-11-19
WO1999059608A2 (en) 1999-11-25
EP1674108A3 (de) 2006-08-02
DE69930622D1 (de) 2006-05-18
AU4027799A (en) 1999-12-06
US6846907B1 (en) 2005-01-25
US20040142871A1 (en) 2004-07-22
WO1999059608A3 (en) 2000-04-06
EP1079847B1 (de) 2006-03-29
JP2002515444A (ja) 2002-05-28
AU767749B2 (en) 2003-11-20
EP1674108A2 (de) 2006-06-28
US6998123B1 (en) 2006-02-14

Similar Documents

Publication Publication Date Title
ATE321565T1 (de) Behandlung von osteoporose
RU2002124123A (ru) Модифицированный фактор viii
BR0011103A (pt) Composição farmacêutica, e, métodos para prevenção ou tratamento de um distúrbio caracterizado por deposição amilóide em um sujeito mamìfero, para determinar o prognóstico de um paciente que está sendo submetido a tratamento de um distúrbio amilóide e para prevenção ou tratamento de uma doença caracterizada por um depósito amilóide em um paciente
HK1041268A1 (en) Connective tissue growth factor (ctgf) fragment
DK0592521T3 (da) Marv-afledte humane mesenchymal-stamceller og monoklonale antistoffer specifikke for nævnte celler
EP0815125A4 (de) gC1q-REZEPTOR, DARAN BINDENDE HIV-1 gp120-REGION, VERWANDTE PEPTIDE UND ANTIKÖRPER
FI963805A (fi) Hermotukisoluista peräisin olevaa neurotrofista tekijää (GDNF) koodaavat yhdistelmä-DNA-tekniset adenovirukset
Castronovo et al. Identification of a 14-kDa laminin binding protein (HLBP14) in human melanoma cells that is identical to the 14-kDa galactoside binding lectin
ATE349523T1 (de) Verfahren zur verwendung eines humanen il-17 verwandten polypeptids zur behandlung von krankheiten
ZA200107283B (en) Vascular adhesion molecules and modulation of their function.
AU4278299A (en) Human receptor tyrosine kinase
ATE265226T1 (de) Verwendung von wolinella succinogenes asparaginase zur behandlung von asparagin- abhängiger krankheiten
WO2003040296A3 (en) Men protein, gst2, rab-rp1, csp, f-box protein lilina/fbl7, abc50, coronin, sec61 alpha, or vhappa1-1, or homologous proteins involved in the regulation of energy homeostasis
IL134436A0 (en) Neisseria lactoferrin binding protein
DE69634994D1 (de) Bindegewebe-wachstumsfaktor 3.
WO2000038706A3 (en) Methods for treating cancer and for mediating chemotaxis of dendritic cells
DE69728654D1 (de) Verwendung von il-7 zur behandlung von autoimmunkrankheiten, insbesondere insulinabhängigem diabetes mellitus
WO1998019160A3 (de) VERFAHREN ZUR INDIREKTEN BESTIMMUNG DER TYP I INTERFERON-PRODUKTION IN VIVO MITTELS ANTIKÖRPER GEGEN HUMANE Mx-PROTEINE SOWIE ANTIKÖRPER HIERZU
NO20015751D0 (no) Nevrotrofiske faktorer i behandlingen av perifer nervedysfunksjon i bekkenområdet
Asokan et al. Neoplastic association of enhanced type V collagen production in rat fibrosarcoma
Mardon et al. A tissue‐specific protein in rat osteogenic tissues
EP1226279A4 (de) Modulation der neurokrinen differenzierung durch protein 25.1
Guyda Final height attainment in normal children with short stature treated with growth hormone
ATE357520T1 (de) Biologisches material zur behandlung eines säugetieres durch transfer einesfür einen antikörper kodierendes gen und eine pharmazeutische zusammensetzungdie diese enthält
Theintz et al. Bone mass growth during normal pubertal development

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties