ATE318909T1 - Konstitutive expression von nicht-infektiöser hiv-ähnlicher teilchen - Google Patents
Konstitutive expression von nicht-infektiöser hiv-ähnlicher teilchenInfo
- Publication number
- ATE318909T1 ATE318909T1 AT98960976T AT98960976T ATE318909T1 AT E318909 T1 ATE318909 T1 AT E318909T1 AT 98960976 T AT98960976 T AT 98960976T AT 98960976 T AT98960976 T AT 98960976T AT E318909 T1 ATE318909 T1 AT E318909T1
- Authority
- AT
- Austria
- Prior art keywords
- particles
- hiv
- constitutive expression
- modified
- genome
- Prior art date
Links
- 239000002245 particle Substances 0.000 title abstract 3
- 208000015181 infectious disease Diseases 0.000 title abstract 2
- 210000004962 mammalian cell Anatomy 0.000 abstract 2
- 239000013604 expression vector Substances 0.000 abstract 1
- 230000002163 immunogen Effects 0.000 abstract 1
- 230000007774 longterm Effects 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 230000003362 replicative effect Effects 0.000 abstract 1
- 231100000331 toxic Toxicity 0.000 abstract 1
- 230000002588 toxic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16023—Virus like particles [VLP]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
- C12N2740/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16311—Human Immunodeficiency Virus, HIV concerning HIV regulatory proteins
- C12N2740/16322—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Virology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Oncology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- AIDS & HIV (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Saccharide Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/991,773 US6121021A (en) | 1997-12-16 | 1997-12-16 | Constitutive expression of non-infectious HIV-like particles |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE318909T1 true ATE318909T1 (de) | 2006-03-15 |
Family
ID=25537545
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT98960976T ATE318909T1 (de) | 1997-12-16 | 1998-12-14 | Konstitutive expression von nicht-infektiöser hiv-ähnlicher teilchen |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US6121021A (https=) |
| EP (1) | EP1038001B8 (https=) |
| JP (1) | JP2004509601A (https=) |
| AT (1) | ATE318909T1 (https=) |
| AU (1) | AU749174B2 (https=) |
| BR (1) | BR9813626A (https=) |
| CA (1) | CA2312943C (https=) |
| DE (1) | DE69833686T2 (https=) |
| DK (1) | DK1038001T3 (https=) |
| ES (1) | ES2262250T3 (https=) |
| PT (1) | PT1038001E (https=) |
| WO (1) | WO1999031250A2 (https=) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6080408A (en) * | 1994-08-22 | 2000-06-27 | Connaught Laboratories Limited | Human immunodeficiency virus type 1 nucleic acids devoid of long terminal repeats capable of encoding for non-infectious, immunogenic, retrovirus-like particles |
| US7135191B2 (en) * | 1997-09-04 | 2006-11-14 | Zsolt Istvan Hertelendy | Urogenital or anorectal transmucosal vaccine delivery system |
| US6121021A (en) * | 1997-12-16 | 2000-09-19 | Connaught Laboratories Limited | Constitutive expression of non-infectious HIV-like particles |
| EP1083230A1 (en) * | 1999-09-10 | 2001-03-14 | Academisch Medisch Centrum Amsterdam | Viral replicons and viruses dependent on inducing agents |
| EP2388015A1 (en) | 2000-03-02 | 2011-11-23 | Emory University | DNA expression vectors and methods of use |
| US20040105871A1 (en) * | 2000-03-02 | 2004-06-03 | Robinson Harriet L. | Compositions and methods for generating an immune response |
| US8623379B2 (en) * | 2000-03-02 | 2014-01-07 | Emory University | Compositions and methods for generating an immune response |
| EP1776961A1 (en) * | 2000-04-27 | 2007-04-25 | Sanofi Pasteur Limited | Immunizing against HIV infection |
| EP1280551B1 (en) * | 2000-04-27 | 2007-01-10 | Sanofi Pasteur Limited | Vaccines against hiv infection |
| US7122180B2 (en) * | 2000-10-23 | 2006-10-17 | Children's Medical Center Corporation | DNA vectors containing mutated HIV proviruses |
| JP4554887B2 (ja) * | 2001-03-08 | 2010-09-29 | アメリカ合衆国 | 改変HIVエンベロープ、gag、およびpol遺伝子を発現するMVA |
| WO2004042001A2 (en) * | 2002-05-17 | 2004-05-21 | Emory University | Virus-like particles, methods of preparation, and immonogenic compositions |
| US9045727B2 (en) * | 2002-05-17 | 2015-06-02 | Emory University | Virus-like particles, methods of preparation, and immunogenic compositions |
| EP2055316A1 (en) * | 2003-09-09 | 2009-05-06 | VIRxSYS Corporation | Lentivirus vector-based approaches for generating an immune response to HIV in humans |
| US20090257983A1 (en) * | 2008-04-11 | 2009-10-15 | Scheiber Lane Bernard | Medical treatment device for treating aids by utilizing modified human immunodeficiency virus virions to insert anti-viral medications into t-helper cells |
| US20110293693A1 (en) * | 2010-05-31 | 2011-12-01 | Scheiber Lane Bernard | Quantum unit of inheritance vector therapy |
| US20110293694A1 (en) * | 2010-05-31 | 2011-12-01 | Scheiber Lane Bernard | Quantum unit of inheritance vector therapy method |
| US9839684B2 (en) | 2011-04-06 | 2017-12-12 | Biovaxim Limited | Pharmaceutical compositions comprising inactivated HIV viral particles and non-pathogenic lactobacilli for the induction of antigen-specific immunotolerance |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5001230A (en) * | 1988-02-18 | 1991-03-19 | Schering Corporation | T cell activation markers |
| GB8923123D0 (en) * | 1989-10-13 | 1989-11-29 | Connaught Lab | A vaccine for human immunodeficiency virus |
| JPH05501201A (ja) * | 1989-10-16 | 1993-03-11 | ホワイトヘツド・インスチチユート・フオー・バイオメデイカル・リサーチ | 非感染性hiv―1粒子およびそれらの使用 |
| EP0502105A4 (en) * | 1989-11-20 | 1993-02-24 | Oncogen Limited Partnership | Non-replicating recombinant-made retroviral particles used as antiviral agents and immunogens |
| JP3494300B2 (ja) * | 1990-04-03 | 2004-02-09 | ジェネンテック・インコーポレーテッド | Hivに対する予防接種のための方法および組成物 |
| AU678152B2 (en) * | 1992-03-27 | 1997-05-22 | Whitehead Institute For Biomedical Research | Non-infectious HIV particles and uses therefor |
| WO1994028929A1 (en) * | 1993-06-07 | 1994-12-22 | Genentech, Inc. | Hiv envelope polypeptides |
| CN1111540C (zh) * | 1993-06-09 | 2003-06-18 | 康诺特实验室有限公司 | 串联的合成hiv-1肽类 |
| US6080408A (en) * | 1994-08-22 | 2000-06-27 | Connaught Laboratories Limited | Human immunodeficiency virus type 1 nucleic acids devoid of long terminal repeats capable of encoding for non-infectious, immunogenic, retrovirus-like particles |
| PT904392E (pt) * | 1996-10-17 | 2001-06-29 | Oxford Biomedica Ltd | Vectores retrovirais |
| IL132164A0 (en) * | 1997-04-09 | 2001-03-19 | Chang Lung Ji | Animal model for evaluation of vaccines |
| US6121021A (en) * | 1997-12-16 | 2000-09-19 | Connaught Laboratories Limited | Constitutive expression of non-infectious HIV-like particles |
-
1997
- 1997-12-16 US US08/991,773 patent/US6121021A/en not_active Expired - Lifetime
-
1998
- 1998-12-14 EP EP98960976A patent/EP1038001B8/en not_active Expired - Lifetime
- 1998-12-14 BR BR9813626-7A patent/BR9813626A/pt not_active Application Discontinuation
- 1998-12-14 PT PT98960976T patent/PT1038001E/pt unknown
- 1998-12-14 ES ES98960976T patent/ES2262250T3/es not_active Expired - Lifetime
- 1998-12-14 AT AT98960976T patent/ATE318909T1/de active
- 1998-12-14 DE DE69833686T patent/DE69833686T2/de not_active Expired - Lifetime
- 1998-12-14 CA CA002312943A patent/CA2312943C/en not_active Expired - Fee Related
- 1998-12-14 DK DK98960976T patent/DK1038001T3/da active
- 1998-12-14 AU AU16577/99A patent/AU749174B2/en not_active Ceased
- 1998-12-14 WO PCT/CA1998/001164 patent/WO1999031250A2/en not_active Ceased
- 1998-12-14 US US09/555,834 patent/US6572863B1/en not_active Expired - Fee Related
- 1998-12-14 JP JP2000539149A patent/JP2004509601A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| BR9813626A (pt) | 2002-07-23 |
| EP1038001B1 (en) | 2006-03-01 |
| AU749174B2 (en) | 2002-06-20 |
| DK1038001T3 (da) | 2006-07-10 |
| DE69833686D1 (de) | 2006-04-27 |
| DE69833686T2 (de) | 2006-11-30 |
| CA2312943A1 (en) | 1999-06-24 |
| ES2262250T3 (es) | 2006-11-16 |
| EP1038001B8 (en) | 2006-09-13 |
| US6121021A (en) | 2000-09-19 |
| WO1999031250A2 (en) | 1999-06-24 |
| EP1038001A2 (en) | 2000-09-27 |
| CA2312943C (en) | 2009-02-24 |
| AU1657799A (en) | 1999-07-05 |
| PT1038001E (pt) | 2006-07-31 |
| US6572863B1 (en) | 2003-06-03 |
| WO1999031250A3 (en) | 1999-08-19 |
| JP2004509601A (ja) | 2004-04-02 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE318909T1 (de) | Konstitutive expression von nicht-infektiöser hiv-ähnlicher teilchen | |
| PL332876A1 (en) | Lentoviral vectors | |
| DE59813758D1 (de) | Herstellung von erythropoietin durch endogene genaktivierung mit viralen promotoren | |
| NO983102L (no) | Uttrykk og forsterkning av sekvenselementer (EASE) for eukaryote ekspresjonssystemer | |
| DK577783A (da) | Vektor for udtrykkelse af et dna-segment i gaer | |
| AU5437886A (en) | Phenotypic modifications of host cells via RNA transformation vector | |
| DK0452484T3 (da) | Fremstilling af proteiner ved homolog rekombination | |
| WO2002088346A3 (en) | A system for inducible expression in eukaryotic cells | |
| TR199801933A2 (xx) | Biyolojik olarak tolare edilebilen d���k molek�ler polietileniminler. | |
| DK1702979T3 (da) | Improved keratinocyte culture and uses thereof | |
| ATE293171T1 (de) | Retrovirale, mit lcmv-glykoprotein pseudotypisierte hybrid-vektoren | |
| AU634289B2 (en) | A multifunctional rna having self-processing activity, the preparation thereof and the use thereof | |
| AU5539898A (en) | Nucleic acid construct for the cell cycle regulated expression of structural genes | |
| TR200001046T2 (tr) | Homolog rekombinasyonda pozitif-negatif seçimi. | |
| AU2520595A (en) | Virosome-mediated intracellular delivery of therapeutic agents | |
| DK0843731T3 (da) | Adenovirusvektorer til genterapi | |
| DE3577994D1 (de) | Vergroessernde virale dna-segmente. | |
| EP0336383A3 (en) | Novel recombinant human lymphotoxin | |
| HUP9902585A2 (hu) | Replikálódó molekulák in vivo előállítása | |
| DK176387D0 (da) | Fremgangsmaade til frembringelse af et funktionelt polypeptid i en eukaryot vaertscelle ved anvendelse af en rekombinant dna udtrykkelsesvektor omfattende en bk virusforstaerker | |
| DK0635061T3 (da) | Fremgangsmåde til begrænsning af genetisk manipulerede organismers overlevelse i deres miljø | |
| EP1032418A4 (en) | COMPACT REPLICONS OF THE EPSTEIN-BARR VIRUS | |
| NO912099L (no) | Ekspresjon av hiv-proteiner i drosophilia-celler. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEFA | Change of the company name | ||
| UEP | Publication of translation of european patent specification |
Ref document number: 1038001 Country of ref document: EP |