ATE314396T1 - G-csf-rezeptoragonist-antikörper und methode zu ihrer isolierung mittels durchmusterung - Google Patents
G-csf-rezeptoragonist-antikörper und methode zu ihrer isolierung mittels durchmusterungInfo
- Publication number
- ATE314396T1 ATE314396T1 AT99918932T AT99918932T ATE314396T1 AT E314396 T1 ATE314396 T1 AT E314396T1 AT 99918932 T AT99918932 T AT 99918932T AT 99918932 T AT99918932 T AT 99918932T AT E314396 T1 ATE314396 T1 AT E314396T1
- Authority
- AT
- Austria
- Prior art keywords
- screening
- csf receptor
- receptor agonist
- agonist antibodies
- receptor
- Prior art date
Links
- 108010054017 Granulocyte Colony-Stimulating Factor Receptors Proteins 0.000 title 1
- 102100039622 Granulocyte colony-stimulating factor receptor Human genes 0.000 title 1
- 238000002955 isolation Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 239000000018 receptor agonist Substances 0.000 title 1
- 229940044601 receptor agonist Drugs 0.000 title 1
- 238000012216 screening Methods 0.000 title 1
- 239000000556 agonist Substances 0.000 abstract 3
- 108020003175 receptors Proteins 0.000 abstract 2
- 101000746364 Homo sapiens Granulocyte colony-stimulating factor receptor Proteins 0.000 abstract 1
- 108091000080 Phosphotransferase Proteins 0.000 abstract 1
- 230000024245 cell differentiation Effects 0.000 abstract 1
- 230000004663 cell proliferation Effects 0.000 abstract 1
- 239000012634 fragment Substances 0.000 abstract 1
- 150000002894 organic compounds Chemical class 0.000 abstract 1
- 230000026731 phosphorylation Effects 0.000 abstract 1
- 238000006366 phosphorylation reaction Methods 0.000 abstract 1
- 102000020233 phosphotransferase Human genes 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/53—Colony-stimulating factor [CSF]
- C07K14/535—Granulocyte CSF; Granulocyte-macrophage CSF
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Veterinary Medicine (AREA)
- Toxicology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Saccharide Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US8357598P | 1998-04-30 | 1998-04-30 | |
| PCT/US1999/009466 WO1999055735A1 (en) | 1998-04-30 | 1999-04-30 | G-csf receptor agonist antibodies and screening method therefor |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE314396T1 true ATE314396T1 (de) | 2006-01-15 |
Family
ID=22179233
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99918932T ATE314396T1 (de) | 1998-04-30 | 1999-04-30 | G-csf-rezeptoragonist-antikörper und methode zu ihrer isolierung mittels durchmusterung |
Country Status (12)
| Country | Link |
|---|---|
| EP (1) | EP1073683B1 (de) |
| JP (1) | JP3979008B2 (de) |
| KR (1) | KR100479790B1 (de) |
| CN (2) | CN101070344A (de) |
| AT (1) | ATE314396T1 (de) |
| AU (2) | AU764653B2 (de) |
| BR (1) | BR9910568A (de) |
| CA (1) | CA2326755A1 (de) |
| DE (1) | DE69929183T2 (de) |
| ES (1) | ES2253887T3 (de) |
| NZ (1) | NZ507782A (de) |
| WO (1) | WO1999055735A1 (de) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030059834A1 (en) * | 2001-02-01 | 2003-03-27 | Chang Nancy T. | Methods to generate and identify monoclonal antibodies to a large number of human antigens |
| MY157796A (en) | 2006-06-08 | 2016-07-29 | Chugai Pharmaceutical Co Ltd | Preventive or remedy for inflammatory disease |
| JP5174019B2 (ja) * | 2007-06-07 | 2013-04-03 | 恵一 福田 | Ｇ−ｃｓｆを用いた心筋細胞への分化誘導方法 |
| CA2708532C (en) | 2007-12-05 | 2018-06-05 | Chugai Seiyaku Kabushiki Kaisha | Anti-il31ra antibody and use thereof |
| GB0812277D0 (en) * | 2008-07-04 | 2008-08-13 | Fusion Antibodies Ltd | Antibody and uses thereof |
| KR20140043720A (ko) | 2011-03-01 | 2014-04-10 | 노보 노르디스크 에이/에스 | 길항성 ｄｒ3 리간드 |
| WO2016167263A1 (ja) | 2015-04-14 | 2016-10-20 | 中外製薬株式会社 | Ｉｌ－３１アンタゴニストを有効成分として含有する、アトピー性皮膚炎の予防用及び／又は治療用医薬組成物 |
| JP5954916B1 (ja) | 2015-04-14 | 2016-07-20 | 中外製薬株式会社 | Ｉｌ−３１アンタゴニストを有効成分として含有する、アトピー性皮膚炎の予防用及び／又は治療用医薬組成物 |
| JP6782716B2 (ja) * | 2015-06-25 | 2020-11-11 | エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ | 抗体またはリガンドの結合および機能を明らかにするための細胞ベースアッセイ法 |
| WO2021100794A1 (ja) | 2019-11-20 | 2021-05-27 | 中外製薬株式会社 | 抗体含有製剤 |
| JPWO2023027177A1 (de) * | 2021-08-26 | 2023-03-02 | ||
| CN114292843B (zh) * | 2021-12-03 | 2023-07-21 | 中国科学院精密测量科学与技术创新研究院 | 一种基因兴奋剂的CRISPR/Cas12a检测体系及其应用 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5362853A (en) * | 1986-12-23 | 1994-11-08 | Kyowa Hakko Kogyo Co., Ltd. | Polypeptide derivatives of human granulocyte colony stimulating factor |
| ATE196548T1 (de) * | 1991-05-10 | 2000-10-15 | Genentech Inc | Auswählen von agonisten und antagonisten von liganden |
| FR2686900B1 (fr) * | 1992-01-31 | 1995-07-21 | Rhone Poulenc Rorer Sa | Nouveaux polypeptides ayant une activite de stimulation des colonies de granulocytes, leur preparation et compositions pharmaceutiques les contenant. |
| US5581476A (en) * | 1993-01-28 | 1996-12-03 | Amgen Inc. | Computer-based methods and articles of manufacture for preparing G-CSF analogs |
| AUPM375094A0 (en) * | 1994-02-08 | 1994-03-03 | Ludwig Institute For Cancer Research | Cytokine receptor interactive molecules and methods for assaying cytokine function |
| WO1995029690A1 (en) * | 1994-04-29 | 1995-11-09 | The Trustees Of The University Of Pennsylvania | Biologically active peptides and methods of identifying the same |
| CA2234042A1 (en) * | 1995-10-05 | 1997-04-10 | G.D. Searle & Co. | Novel g-csf receptor agonists |
-
1999
- 1999-04-30 CA CA002326755A patent/CA2326755A1/en not_active Abandoned
- 1999-04-30 KR KR10-2000-7012001A patent/KR100479790B1/ko not_active Expired - Fee Related
- 1999-04-30 BR BR9910568-3A patent/BR9910568A/pt not_active Application Discontinuation
- 1999-04-30 JP JP2000545893A patent/JP3979008B2/ja not_active Expired - Lifetime
- 1999-04-30 DE DE69929183T patent/DE69929183T2/de not_active Expired - Fee Related
- 1999-04-30 ES ES99918932T patent/ES2253887T3/es not_active Expired - Lifetime
- 1999-04-30 NZ NZ507782A patent/NZ507782A/en not_active Application Discontinuation
- 1999-04-30 AT AT99918932T patent/ATE314396T1/de not_active IP Right Cessation
- 1999-04-30 CN CNA2007101075999A patent/CN101070344A/zh active Pending
- 1999-04-30 AU AU36732/99A patent/AU764653B2/en not_active Ceased
- 1999-04-30 CN CNB998056065A patent/CN1326880C/zh not_active Expired - Fee Related
- 1999-04-30 EP EP99918932A patent/EP1073683B1/de not_active Expired - Lifetime
- 1999-04-30 WO PCT/US1999/009466 patent/WO1999055735A1/en not_active Ceased
-
2003
- 2003-10-07 AU AU2003252863A patent/AU2003252863A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| AU3673299A (en) | 1999-11-16 |
| EP1073683A4 (de) | 2001-08-22 |
| WO1999055735A1 (en) | 1999-11-04 |
| NZ507782A (en) | 2003-12-19 |
| JP3979008B2 (ja) | 2007-09-19 |
| CN1298412A (zh) | 2001-06-06 |
| DE69929183T2 (de) | 2006-08-24 |
| DE69929183D1 (de) | 2006-02-02 |
| EP1073683A1 (de) | 2001-02-07 |
| JP2002512782A (ja) | 2002-05-08 |
| CN1326880C (zh) | 2007-07-18 |
| EP1073683B1 (de) | 2005-12-28 |
| KR100479790B1 (ko) | 2005-03-30 |
| KR20010043112A (ko) | 2001-05-25 |
| AU2003252863A1 (en) | 2003-11-06 |
| CA2326755A1 (en) | 1999-11-04 |
| BR9910568A (pt) | 2001-09-11 |
| CN101070344A (zh) | 2007-11-14 |
| ES2253887T3 (es) | 2006-06-01 |
| AU764653B2 (en) | 2003-08-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |