ATE313528T1 - 4-(phenyl(piperidin-4-yl)amino) benzamidderivate und deren verwendung zur behandlung von schmerzen,angst oder gastrointestinalen störungen - Google Patents
4-(phenyl(piperidin-4-yl)amino) benzamidderivate und deren verwendung zur behandlung von schmerzen,angst oder gastrointestinalen störungenInfo
- Publication number
- ATE313528T1 ATE313528T1 AT02733702T AT02733702T ATE313528T1 AT E313528 T1 ATE313528 T1 AT E313528T1 AT 02733702 T AT02733702 T AT 02733702T AT 02733702 T AT02733702 T AT 02733702T AT E313528 T1 ATE313528 T1 AT E313528T1
- Authority
- AT
- Austria
- Prior art keywords
- piperidin
- anxiety
- pain
- phenyl
- amino
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/56—Nitrogen atoms
- C07D211/58—Nitrogen atoms attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE0101769A SE0101769D0 (sv) | 2001-05-18 | 2001-05-18 | Novel compounds |
| PCT/SE2002/000944 WO2002094782A1 (en) | 2001-05-18 | 2002-05-16 | 4-(phenyl-(piperidin-4-yl)-amino)-benzamide derativatives and their use for the treatment of pain, anxiety or gastrointestinal disorders |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE313528T1 true ATE313528T1 (de) | 2006-01-15 |
Family
ID=20284172
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02733702T ATE313528T1 (de) | 2001-05-18 | 2002-05-16 | 4-(phenyl(piperidin-4-yl)amino) benzamidderivate und deren verwendung zur behandlung von schmerzen,angst oder gastrointestinalen störungen |
Country Status (26)
| Country | Link |
|---|---|
| US (1) | US7226933B2 (enExample) |
| EP (1) | EP1395555B1 (enExample) |
| JP (1) | JP2005508289A (enExample) |
| KR (1) | KR20030094425A (enExample) |
| CN (1) | CN1639123A (enExample) |
| AR (1) | AR033758A1 (enExample) |
| AT (1) | ATE313528T1 (enExample) |
| BG (1) | BG108330A (enExample) |
| BR (1) | BR0209670A (enExample) |
| CA (1) | CA2446311A1 (enExample) |
| CO (1) | CO5540317A2 (enExample) |
| CZ (1) | CZ20033089A3 (enExample) |
| DE (1) | DE60208192T2 (enExample) |
| EE (1) | EE200300554A (enExample) |
| HU (1) | HUP0401328A2 (enExample) |
| IL (1) | IL158628A0 (enExample) |
| IS (1) | IS7028A (enExample) |
| MX (1) | MXPA03010440A (enExample) |
| NO (1) | NO20035113D0 (enExample) |
| NZ (1) | NZ529398A (enExample) |
| PL (1) | PL366387A1 (enExample) |
| RU (1) | RU2003131966A (enExample) |
| SE (1) | SE0101769D0 (enExample) |
| SK (1) | SK13912003A3 (enExample) |
| WO (1) | WO2002094782A1 (enExample) |
| ZA (1) | ZA200308631B (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2322950T3 (es) * | 2002-03-13 | 2009-07-02 | Janssen Pharmaceutica Nv | Derivados de aminocarbonilo como nuevos inhibidores de histona-desacetilasa. |
| SE0300987D0 (sv) * | 2003-04-03 | 2003-04-03 | Astrazeneca Ab | Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof |
| JP4976134B2 (ja) | 2003-10-01 | 2012-07-18 | アドラー コーポレーション | スピロ環複素環誘導体及びそれらを使用する方法 |
| US7598261B2 (en) | 2005-03-31 | 2009-10-06 | Adolor Corporation | Spirocyclic heterocyclic derivatives and methods of their use |
| US7576207B2 (en) * | 2006-04-06 | 2009-08-18 | Adolor Corporation | Spirocyclic heterocyclic derivatives and methods of their use |
| MX2009002715A (es) * | 2006-09-12 | 2009-08-12 | Adolor Corp | Metodos para mejorar la funcion cognoscitiva. |
| SI3233825T1 (sl) * | 2014-12-19 | 2020-10-30 | Pharmnovo Ab | Derivati diarilmetiliden-piperidina in njihova uporaba kot agonisti delta opioidnega receptorja |
| WO2022235813A1 (en) * | 2021-05-04 | 2022-11-10 | The Texas A&M University System | Inhibitors of sars-cov-2 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4091096A (en) * | 1976-03-19 | 1978-05-23 | Eli Lilly And Company | Dinitroanilines for the control of phytopathogens |
| EG12406A (en) * | 1976-08-12 | 1979-03-31 | Janssen Pharmaceutica Nv | Process for preparing of novel n-aryl-n-(1-l-4-piperidinyl)-arylacetamides |
| SE441448B (sv) | 1977-05-23 | 1985-10-07 | Pfizer | Sett att framstella hexahydro-gamma-karbolinforeningar |
| US4252812A (en) * | 1977-05-23 | 1981-02-24 | Pfizer Inc. | 2-Substituted-trans-5-aryl-2,3,4,4a,5,9b-hexahydro-1H-pyrido[4,3-b]indoles |
| DE3200304A1 (de) * | 1981-01-16 | 1982-08-26 | Sandoz-Patent-GmbH, 7850 Lörrach | 3-aminopropoxyaryl-derivate, ihre herstellung und sie enthaltende arzneimittel |
| DE3563964D1 (en) * | 1984-10-16 | 1988-09-01 | Synthelabo | Piperidine derivatives, their preparation and their therapeutical application |
| KR940003491B1 (ko) * | 1989-08-10 | 1994-04-23 | 리히터 게데온 베기에스제티 기아르 알.티 | 4,4-이중 치환된 피페리딘 유도체와 그 제조방법 및 상기 화합물을 함유하는 약제학적 조성물 |
| YU150489A (sh) * | 1989-08-10 | 1992-12-21 | W.L. Gore & Co. Gmbh. | Uređaj za ispitivanje odevnih predmeta na nepromočivost |
| US5854245A (en) * | 1996-06-28 | 1998-12-29 | Merck & Co., Inc. | Fibrinogen receptor antagonists |
| TW548271B (en) * | 1996-12-20 | 2003-08-21 | Astra Pharma Inc | Novel piperidine derivatives having an exocyclic double bond with analgesic effects |
| SE9604786D0 (sv) * | 1996-12-20 | 1996-12-20 | Astra Pharma Inc | New compounds |
| ZA9811842B (en) | 1997-12-24 | 2000-06-23 | Ortho Mcneil Pharm Inc | 4-[aryl(piperidin-4-yl)]aminobenzamides. |
| CA2683097A1 (en) | 1998-03-10 | 1999-09-16 | Research Triangle Institute | Novel opiate compounds, methods of making and methods of use |
| SE9904675D0 (sv) | 1999-12-20 | 1999-12-20 | Astra Pharma Inc | Novel compounds |
| IL151550A0 (en) * | 2000-03-03 | 2003-04-10 | Ortho Mcneil Pharm Inc | 3-(diarylmethylene)-8-azabicyclo [3.2.1] octane derivatives |
| SE0001207D0 (sv) * | 2000-04-04 | 2000-04-04 | Astrazeneca Canada Inc | Novel compounds |
| JPWO2009028275A1 (ja) * | 2007-08-28 | 2010-11-25 | コニカミノルタエムジー株式会社 | シンチレータパネル |
-
2001
- 2001-05-18 SE SE0101769A patent/SE0101769D0/xx unknown
-
2002
- 2002-05-16 SK SK1391-2003A patent/SK13912003A3/sk unknown
- 2002-05-16 JP JP2002591455A patent/JP2005508289A/ja active Pending
- 2002-05-16 WO PCT/SE2002/000944 patent/WO2002094782A1/en not_active Ceased
- 2002-05-16 CZ CZ20033089A patent/CZ20033089A3/cs unknown
- 2002-05-16 RU RU2003131966/04A patent/RU2003131966A/ru not_active Application Discontinuation
- 2002-05-16 US US10/477,852 patent/US7226933B2/en not_active Expired - Fee Related
- 2002-05-16 NZ NZ529398A patent/NZ529398A/en unknown
- 2002-05-16 PL PL02366387A patent/PL366387A1/xx not_active Application Discontinuation
- 2002-05-16 CA CA002446311A patent/CA2446311A1/en not_active Abandoned
- 2002-05-16 AT AT02733702T patent/ATE313528T1/de not_active IP Right Cessation
- 2002-05-16 EP EP02733702A patent/EP1395555B1/en not_active Expired - Lifetime
- 2002-05-16 BR BR0209670-6A patent/BR0209670A/pt not_active IP Right Cessation
- 2002-05-16 IL IL15862802A patent/IL158628A0/xx unknown
- 2002-05-16 KR KR10-2003-7014946A patent/KR20030094425A/ko not_active Withdrawn
- 2002-05-16 DE DE60208192T patent/DE60208192T2/de not_active Expired - Fee Related
- 2002-05-16 MX MXPA03010440A patent/MXPA03010440A/es unknown
- 2002-05-16 EE EEP200300554A patent/EE200300554A/xx unknown
- 2002-05-16 AR ARP020101814A patent/AR033758A1/es unknown
- 2002-05-16 CN CNA028141601A patent/CN1639123A/zh active Pending
- 2002-05-16 HU HU0401328A patent/HUP0401328A2/hu unknown
-
2003
- 2003-11-05 ZA ZA200308631A patent/ZA200308631B/xx unknown
- 2003-11-07 BG BG108330A patent/BG108330A/bg unknown
- 2003-11-12 IS IS7028A patent/IS7028A/is unknown
- 2003-11-12 CO CO03100165A patent/CO5540317A2/es not_active Application Discontinuation
- 2003-11-17 NO NO20035113A patent/NO20035113D0/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| NO20035113D0 (no) | 2003-11-17 |
| WO2002094782A1 (en) | 2002-11-28 |
| IS7028A (is) | 2003-11-12 |
| SK13912003A3 (sk) | 2004-04-06 |
| SE0101769D0 (sv) | 2001-05-18 |
| EP1395555A1 (en) | 2004-03-10 |
| CO5540317A2 (es) | 2005-07-29 |
| BR0209670A (pt) | 2004-04-20 |
| NZ529398A (en) | 2005-08-26 |
| IL158628A0 (en) | 2004-05-12 |
| ZA200308631B (en) | 2005-02-07 |
| MXPA03010440A (es) | 2004-03-09 |
| EE200300554A (et) | 2004-02-16 |
| RU2003131966A (ru) | 2005-05-10 |
| PL366387A1 (en) | 2005-01-24 |
| KR20030094425A (ko) | 2003-12-11 |
| BG108330A (bg) | 2004-12-30 |
| JP2005508289A (ja) | 2005-03-31 |
| DE60208192D1 (de) | 2006-01-26 |
| CN1639123A (zh) | 2005-07-13 |
| EP1395555B1 (en) | 2005-12-21 |
| AR033758A1 (es) | 2004-01-07 |
| HUP0401328A2 (hu) | 2004-12-28 |
| CA2446311A1 (en) | 2002-11-28 |
| DE60208192T2 (de) | 2006-07-13 |
| CZ20033089A3 (en) | 2004-06-16 |
| US20040235897A1 (en) | 2004-11-25 |
| US7226933B2 (en) | 2007-06-05 |
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| ATE333452T1 (de) | 4-(penylpiperidin-4-ylidenmethyl)benzamidderiva e und deren verwendung zur behandlung von schmerzen,angstzuständen oder erkrankungen des magen-darm- trakts | |
| ATE313529T1 (de) | 4-(phenyl(piperidin-4-yl)amino) benzamidderivate und deren verwendung zur behandlung von schmerzen,angst oder gastrointestinalen störungen | |
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| DE60117122D1 (de) | Verwendung von mirtazapin zur behandlung von schlafstörungen | |
| EE200300526A (et) | 4-(fenüül(piperidiin-4-üül)amino)bensamiidi derivaadid ja nende kasutamine valu, ärevuse või seedetrakti häirete raviks |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |